In quiet debut, Alzheimer's drug finds questions, skepticism
Persistent concerns about the first new Alzheimer’s treatment in more than 20 years are curbing access more than four months after regulators approved it (Source: ABC News: Health)
Source: ABC News: Health - October 17, 2021 Category: Consumer Health News Tags: Health Source Type: news

In Quiet Debut, Alzheimer's Drug Rollout Slowed By Questions, Skepticism
Persistent concerns about Aduhelm, the disease's first new treatment in about 20 years, are curbing access more than four months after regulators approved it. (Source: Science - The Huffington Post)
Source: Science - The Huffington Post - October 17, 2021 Category: Science Source Type: news

' Fascinating' Link Between Alzheimer's and COVID-19'Fascinating' Link Between Alzheimer's and COVID-19
Alzheimer's risk and susceptibility to severe COVID-19 share a common genetic mechanism; the new findings that could lead to novel treatments to slow progression and severity of both diseases.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - October 13, 2021 Category: Infectious Diseases Tags: Psychiatry News Source Type: news

Ultrasound trial offers hope for brain cancer patients
New technique temporarily allows drugs to cross blood brain barrier to treat tumoursA technique has been developed that could revolutionise thetreatment of brain cancers and neurodegenerative diseases by temporarily allowing drugs and other substances to cross the blood brain barrier – a structure that separates the brain’s blood vessels from the rest of its tissues.A trial in four women whose breast cancer had spread to the brain showed that magnetic resonance-guided focused ultrasound (MRgFUS) could safely deliver the antibody therapy Herceptin into their brain tissue, causing the tumours to shrink.Continue r...
Source: Guardian Unlimited Science - October 13, 2021 Category: Science Authors: Linda Geddes Tags: Medical research Neuroscience Breast cancer Alzheimer's Health Society Source Type: news

Alzheimer’s disease: The personality trait that doubles the risk of mental decline
IN THE absence of disease-halting treatments for Alzheimer's disease, early characterisation of the condition and its risk factors remain the world's best hope for managing the illness. One new study has warned that two personality traits could predispose individuals to cognitive decline. (Source: Daily Express - Health)
Source: Daily Express - Health - October 13, 2021 Category: Consumer Health News Source Type: news

Roche's anti-amyloid beta antibody gantenerumab granted FDA Breakthrough Therapy Designation in Alzheimer's disease
Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that gantenerumab, an anti-amyloid beta antibody developed for subcutaneous administration, has been granted Breakthrough Therapy Designation by the U.S. Food and Drug Administration (FDA) for the treatment of people living with Alzheimer's disease (AD). (Source: World Pharma News)
Source: World Pharma News - October 13, 2021 Category: Pharmaceuticals Tags: Featured Roche Business and Industry Source Type: news

Data up to 8-years for Roche ’s OCREVUS (ocrelizumab) show early and ongoing treatment significantly reduced risk of requiring a walking aid in relapsing multiple sclerosis and disability progression in primary progressive multiple sclerosis
Basel, 13 October 2021 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new long-term data that reinforce the benefit of early initiation and ongoing treatment of OCREVUS® (ocrelizumab) on disability progression in relapsing multiple sclerosis (RMS) and primary progressive MS (PPMS), as well as safety outcomes for an analysis of shorter 2-hour infusion in minority populations. OCREVUS data from all clinical trials consistently show a favourable benefit-risk profile over eight years. Roche and research partners will also present four late-breaking abstracts to share the latest data regarding COVID-19 and vacci...
Source: Roche Media News - October 13, 2021 Category: Pharmaceuticals Source Type: news

Data up to 8-years for Roche ’s OCREVUS (ocrelizumab) show early and ongoing treatment significantly reduced risk of requiring a walking aid in relapsing multiple sclerosis and disability progression in primary progressive multiple sclerosis
Basel, 13 October 2021 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new long-term data that reinforce the benefit of early initiation and ongoing treatment of OCREVUS® (ocrelizumab) on disability progression in relapsing multiple sclerosis (RMS) and primary progressive MS (PPMS), as well as safety outcomes for an analysis of shorter 2-hour infusion in minority populations. OCREVUS data from all clinical trials consistently show a favourable benefit-risk profile over eight years. Roche and research partners will also present four late-breaking abstracts to share the latest data regarding COVID-19 and vacci...
Source: Roche Investor Update - October 13, 2021 Category: Pharmaceuticals Source Type: news

Repurposed Drug Reverses Signs of Alzheimer's in Mice, Human Cells
Researchers say they hope to launch a clinical trial to test bumetanide, a diuretic approved in 2002, but how it might improve neural functioning is unclear. (Source: The Scientist)
Source: The Scientist - October 12, 2021 Category: Science Tags: News & Opinion Source Type: news

DTI-MRI could help predict onset of Alzheimer's disease
MRI with a diffusion-tensor imaging (DTI) protocol could help clinicians predic...Read more on AuntMinnie.comRelated Reading: Could machine learning help clinicians better diagnose autism? MRI finds brain structure changes in elite rugby players MRI shows how head impacts affect brains of young football players Up to 40% of COVID-19 survivors experience neurological effects DTI-MRI shows effects of anesthesia on brain's white matter (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 12, 2021 Category: Radiology Source Type: news

New report shows more than 260 medicines in development to fight neurodegenerative diseases
With neurodegenerative diseases affecting millions of individuals in the United States, now is an important time to spotlight the increasing impact these diseases have on our country ’s aging population and their families. (Source: The Catalyst)
Source: The Catalyst - October 12, 2021 Category: Pharmaceuticals Tags: Medicines in Development Research and Development Alzheimer's Chronic Disease Parkinson's Source Type: news

Older blood pressure drug may reduce Alzheimer's disease risk, study finds
A diuretic commonly used to treat high blood pressure may help prevent the onset of Alzheimer's disease in people who have a high genetic risk, a study published Monday by Nature Aging found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 11, 2021 Category: Consumer Health News Source Type: news

Evidence may be lacking for automated MRI analysis in dementia
There's currently a "significant evidence gap" for the use of many availabl...Read more on AuntMinnie.comRelated Reading: MRI links obstructive sleep apnea and dementia MRI shows link between white-matter hyperintensities and brain health Tau PET bests amyloid PET, MRI in Alzheimer's prognostic study MRI study looks for signs of Alzheimer's disease MRI links air pollution to dementia risk in women (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 11, 2021 Category: Radiology Source Type: news

Dementia diet: Eating just a tablespoon of this food every day can reduce risk
DEMENTIA diet: Research suggests cutting certain foods from your daily life can slash your risk of developing dementia and Alzheimer's disease. But could just one tablespoon of this food reduce your risk of high cholesterol? (Source: Daily Express - Health)
Source: Daily Express - Health - October 11, 2021 Category: Consumer Health News Source Type: news

How biodiversity loss is jeopardising the drugs of the future
From willow bark to mosquitoes, nature has been a source of vital medications for centuries. But species die-off caused by human activity is putting this at riskWhat will biodiversity loss mean for drug discovery?Traditionally used as a painkiller for headaches, snowdrops are now known to slow the onset of dementia.In the 1950s, a natural alkaloid called galantamine was extracted from the bulbs. Today, a synthesised version of this is used to treatAlzheimer ’s disease and scientists are investigating further to see if snowdrops might also be effectivein the treatment of HIV.However, over-harvesting has resulted inman...
Source: Guardian Unlimited Science - October 9, 2021 Category: Science Authors: Katherine Latham Tags: Biodiversity Science Alzheimer's Medicine Malaria Parkinson's disease Antibiotics Plants Insects Environment Health Wildlife Conservation Source Type: news

Alzheimer ’s Risk Gene Paradoxically Protects Against Memory Loss
A new study links a variant of the apolipoprotein E gene called APOE ?4 to better memory in older age, even in the presence of amyloid plaques —a possible explanation for the variant’s persistence... (Source: The Scientist)
Source: The Scientist - October 8, 2021 Category: Science Tags: News & Opinion Source Type: news

A New Tool for Predicting Alzheimer's? A New Tool for Predicting Alzheimer's?
A higher polygenic risk score has shown potential in predicting late-onset Alzheimer's disease, new research shows.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 8, 2021 Category: Neurology Tags: Psychiatry News Source Type: news

Precision medicine data dive shows water pill may be viable to test as Alzheimer ’s treatment
NIH-funded research reveals clinical trial candidate for those with genetic risk. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - October 8, 2021 Category: American Health Source Type: news

AI cuts PET scan time in Alzheimer's disease
An artificial intelligence (AI) algorithm was able to reduce the time require...Read more on AuntMinnie.comRelated Reading: Tau PET best for imaging Alzheimer's disease progression PET radiotracer tweaked for greater precision in AD detection 'Early frame' PET may reduce cost and burden in Alzheimer's disease PET/MRI study looks at head injuries and Alzheimer's disease PET shows aerobic exercise has little effect on amyloid (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 8, 2021 Category: Radiology Source Type: news

Life in the present tense
It was the cards I noticed first this morning. Each one neatly placed on the windowsill. Carefully butted up against the thin line of mastic securing glass into frame; they were spaced almost exactly it seemed, but without the benefit of a ruler I couldn’t be sure. They ran in order, Hearts, then Spades, Diamonds and finally Clubs; each suit starting Ace’s low. You were moving slowly, gathering them up into a neat stack and beginning to lay them out again. I watched you for a while before going to the kitchen to make the first of many cups of tea. The kettle boiled, I poured water into two mugs on top of the te...
Source: The Hysterectomy Association - October 7, 2021 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Fiction alzheimers short story Source Type: news

Dementia: 'Better memory' could be a risk factor for Alzheimer's - surprising finding
UNDERSTANDING the mechanisms that drive dementia raises the possibility of thwarting its development. A team of scientists at UCL have found that having an Alzheimer's risk gene is also linked to "better visual memory" - a finding that at first glance will seem counterintuitive. (Source: Daily Express - Health)
Source: Daily Express - Health - October 7, 2021 Category: Consumer Health News Source Type: news

ANOTHER study finds Alzheimer's may be detectable years before symptoms begin
The disease, which is the most common cause of dementia in the UK, may trigger detectable changes in the brain structure of people who have a higher risk of developing the condition. (Source: the Mail online | Health)
Source: the Mail online | Health - October 7, 2021 Category: Consumer Health News Source Type: news

You may now be able to assess your dementia risk 'long before' symptoms show - major study
EARLY dementia detection is key to slowing down and even forestalling brain decline. A new study published today suggests changes in healthy people who have a genetic risk of Alzheimer's disease can be picked up "long before" symptoms surface. (Source: Daily Express - Health)
Source: Daily Express - Health - October 6, 2021 Category: Consumer Health News Source Type: news

Alzheimer’s disease: The sign when brushing your teeth that could indicate rapid decline
ALZHEIMER'S disease is a crippling condition characterised by progressive cognitive impairment, beyond what can be expected as a consequence of old age. One sign when brushing your teeth may signal you're at risk. (Source: Daily Express - Health)
Source: Daily Express - Health - October 6, 2021 Category: Consumer Health News Source Type: news

New brain maps could help the search for Alzheimer's treatments
Scientists have created detailed maps of the brain area that controls movement in mice, monkeys and people. The maps could help explain human ailments like Alzheimer's and Lou Gehrig's disease. (Image credit: Allen Institute for Brain Science) (Source: NPR Health and Science)
Source: NPR Health and Science - October 6, 2021 Category: Consumer Health News Authors: Jon Hamilton Source Type: news

UTSA gets nearly $13M for brain cancer research
UTSA will assist in the five-year study into the treatment of elimination of multiple neurological diseases, including epilepsy and Alzheimer ’s. (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - October 6, 2021 Category: Health Management Authors: W. Scott Bailey Source Type: news

NIH Director Francis S. Collins to Step Down by End of Year
Dr. Francis S. Collins, director of the National Institutes of Health for 12 years, said Tuesday he is stepping down, capping a career in which he directed crucial research into the human genome and the fight against serious diseases like cancer, Alzheimer’s, diabetes and COVID-19. Collins said he was “grateful and proud of the NIH staff and the scientific community, whose extraordinary commitment to lifesaving research delivers hope to the American people and the world every day.” He said the decision to step down at year’s end was “a difficult one.” “I fundamentally believe, howe...
Source: TIME: Health - October 5, 2021 Category: Consumer Health News Authors: DINO HAZELL/AP Tags: Uncategorized Public Health wire Source Type: news

MRI links obstructive sleep apnea and dementia
Brain MRI findings suggest treating people with obstructive sleep apnea coul...Read more on AuntMinnie.comRelated Reading: Brain MRI shows link between atrial fibrillation and cognitive decline MRI shows link between white-matter hyperintensities and brain health PET/MRI study looks at head injuries and Alzheimer's disease MRI shows slimmer tongue reduces sleep apnea MRI shows less gray matter in kids with sleep apnea (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 5, 2021 Category: Radiology Source Type: news

Lady Gaga Recalls Moment Tony Bennett Remembered Her Name Amid Alzheimer ’s Battle: “My Friend Saw Me”
The musician and actress appeared on Sunday’s episode of '60 Minutes' to talk about performing with Bennett, who was diagnosed with... (Source: Reuters: Health)
Source: Reuters: Health - October 4, 2021 Category: Consumer Health News Source Type: news

ADHD Med May Reduce Apathy in Alzheimer's Disease ADHD Med May Reduce Apathy in Alzheimer's Disease
Methylphenidate is associated with a significantly greater reduction in apathy in patients with Alzheimer's disease compared with placebo -- and has a good safety profile, a new phase 3 trial suggests.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 4, 2021 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Getting flu jab for six years in a row cuts risk of developing dementia by 14%
Britain faces an epidemic of Alzheimer's disease and dementia due to an ageing population. The numbers affected are forecast to jump from to more than 1.2million in England and Wales in 2040. (Source: the Mail online | Health)
Source: the Mail online | Health - October 4, 2021 Category: Consumer Health News Source Type: news

Revolutionary drug 'could reverse damage' caused by Alzheimer's
Paul Brennan, chief executive of Canadian biotech firm NervGen, said a revolutionary new drug, codenamed NVG-291, could transform the treatment of Alzheimer's. (Source: the Mail online | Health)
Source: the Mail online | Health - October 4, 2021 Category: Consumer Health News Source Type: news

Levetiracetam Well Tolerated for Alzheimer Disease
Does not improve primary outcome, but did improve performance on certain cognitive tasks in those with epileptiform activity (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - October 1, 2021 Category: Psychiatry Tags: Neurology, Pharmacy, Psychiatry, Journal, Source Type: news

Scientists Untangle Why Diabetes Might Raise Alzheimer's Risk
Title: Scientists Untangle Why Diabetes Might Raise Alzheimer's RiskCategory: Health NewsCreated: 10/1/2021 12:00:00 AMLast Editorial Review: 10/1/2021 12:00:00 AM (Source: MedicineNet Alzheimer)
Source: MedicineNet Alzheimer - October 1, 2021 Category: Geriatrics Source Type: news

Yeast Models Provide New Insights into Neurodegenerative Diseases
The single-celled fungus allows researchers to study Alzheimer ’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale. (Source: The Scientist)
Source: The Scientist - October 1, 2021 Category: Science Tags: Features Magazine Issue Source Type: news

New Bloomberg Distinguished Professor
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Source: Johns Hopkins University and Health Systems Archive - September 30, 2021 Category: Nursing Source Type: news

Diagnosing Alzheimer's: Which Blood Test Is Best? Diagnosing Alzheimer's: Which Blood Test Is Best?
Blood tests are a promising approach to Alzheimer's disease screening, but new research shows that some tests are more much accurate than others.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - September 30, 2021 Category: Internal Medicine Tags: Psychiatry News Source Type: news

Driving and Alzheimer's dementia or mild cognitive impairment: a systematic review of the existing guidelines emphasizing on the neurologist's role - Stamatelos P, Economou A, Stefanis L, Yannis G, Papageorgiou SG.
BACKGROUND: Driving is a complex task requiring the integrity and the cooperation of cognition, motor, and somatosensory skills, all of which are impacted by neurological diseases. OBJECTIVE: Identification of neurologist's role when assessing fitn... (Source: SafetyLit)
Source: SafetyLit - September 30, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

More setbacks for Biogen: state's largest hospital system spurns Alzheimer's drug
The state's largest health care provider has declined to administer Biogen Inc.'s new Alzheimer's drug, citing concerns over its safety and efficacy months after a controversial FDA approval. Mass General Brigham told the Boston Globe on Tuesday that it would not be using the drug, Aduhelm, generically known as aducanumab. The provider joins a growing cadre of health systems and insurers who are spurning the drug; that group also includes insurance provider Point32Health, one of the la rgest health… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - September 29, 2021 Category: American Health Authors: Rowan Walrath Source Type: news

This Diet May Guard Against Alzheimer's
Title: This Diet May Guard Against Alzheimer'sCategory: Health NewsCreated: 9/29/2021 12:00:00 AMLast Editorial Review: 9/29/2021 12:00:00 AM (Source: MedicineNet Alzheimer)
Source: MedicineNet Alzheimer - September 29, 2021 Category: Geriatrics Source Type: news

MIND Diet Preserves Cognition With Alzheimer's
MIND Diet Preserves Cognition Even in the Presence of Alzheimer's Pathology (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 29, 2021 Category: General Medicine Source Type: news

MIND Diet Preserves Cognition, New Data Show MIND Diet Preserves Cognition, New Data Show
Better adherence to the MIND diet can improve memory and thinking skills of older adults, even in the presence of Alzheimer's disease pathology, new data indicate.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - September 28, 2021 Category: Internal Medicine Tags: Psychiatry News Source Type: news

Dementia: Five early warning signs of Alzheimer's in a person's 40s, 50s or 60s
ALZHEIMER'S disease affecting people under the age of 65 can be attributed to risk factors, such as smoking, drinking too much alcohol, a sedentary lifestyle and unhealthy diet. (Source: Daily Express - Health)
Source: Daily Express - Health - September 28, 2021 Category: Consumer Health News Source Type: news

FDA issues draft guidance for electronic 510(k)s
The U.S. Food and Drug Administration (FDA) has issued a draft guidance fo...Read more on AuntMinnie.comRelated Reading: FDA faces research hurdles in regulating AI for imaging FDA launches online 510(k) submission tracker FDA warns of poor image quality at NY breast center FDA approves Alzheimer's treatment under accelerated pathway FDA releases final guidance on medical device safety for MRI (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 28, 2021 Category: Radiology Source Type: news

Feasibility and acceptability of a web-based caregiver decision aid (Safety in Dementia) for firearm access: pilot randomized controlled trial - Betz ME, Polzer E, Nearing K, Knoepke CE, Johnson RL, Meador L, Matlock DD.
BACKGROUND: Firearms are common in the households of persons with Alzheimer disease and related dementias (ADRD). Safety in Dementia (SiD) is a free web-based decision aid that was developed to support ADRD caregivers in addressing firearm access. ... (Source: SafetyLit)
Source: SafetyLit - September 24, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

New Way to Spot Early Alzheimer's
Title: New Way to Spot Early Alzheimer'sCategory: Health NewsCreated: 9/23/2021 12:00:00 AMLast Editorial Review: 9/24/2021 12:00:00 AM (Source: MedicineNet Alzheimer)
Source: MedicineNet Alzheimer - September 24, 2021 Category: Geriatrics Source Type: news

Dementia: The 'subtle' symptoms that can show up '18 years' before a diagnosis - study
DEMENTIA research aims to forestall brain decline by identifying the earliest indicators of it. A pioneering test found "subtle" indications of Alzheimer's disease - the most common form of dementia - 18 years before a diagnosis. (Source: Daily Express - Health)
Source: Daily Express - Health - September 23, 2021 Category: Consumer Health News Source Type: news

3 charged in death of 86-year-old woman left outside in heat
Colorado officials say three assisted living facility workers are being prosecuted in the death of an 86-year-old woman with Alzheimer’s disease who was allegedly left outside in sweltering weather (Source: ABC News: Health)
Source: ABC News: Health - September 22, 2021 Category: Consumer Health News Tags: Health Source Type: news

3 charged in death of elderly woman left outside in heat
Colorado officials say three assisted living facility workers are being prosecuted in the death of an 86-year-old woman with Alzheimer’s disease who was allegedly left outside in sweltering weather (Source: ABC News: Health)
Source: ABC News: Health - September 22, 2021 Category: Consumer Health News Tags: Health Source Type: news

Traumatic brain injury accelerates the onset of cognitive dysfunction and aggravates Alzheimer's-like pathology in the hippocampus by altering the phenotype of microglia in the APP/PS1 mouse model - Wu D, Kumal JPP, Lu X, Li Y, Mao D, Tang X, Nie M, Liu X, Sun L, Liu B, Zhang Y.
An increasing number of studies have suggested that traumatic brain injury (TBI) is associated with some neurodegenerative diseases, including Alzheimer's disease (AD). Various aspects of the mechanism of TBI-induced AD have been elucidated. However, there... (Source: SafetyLit)
Source: SafetyLit - September 22, 2021 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news