FDDNP-PET shows brain injury effects in military personnel
Researchers have found that changes in PET scans of military personnel with...Read more on AuntMinnie.comRelated Reading: Did PET scan confirm CTE in living NFL player? MRI shows promise in diagnosing CTE in living patients FDDNP-PET gives insight into brain trauma of NFL players FDDNP-PET shows toll of concussions on retired NFL players FDDNP-PET helps predict Alzheimer's progression (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 19, 2018 Category: Radiology Source Type: news

Amyloid pathology fingerprint differentiates post-traumatic stress disorder and traumatic brain injury - Mohamed AZ, Cumming P, Srour H, Gunasena T, Uchida A, Haller CN, Nasrallah F.
INTRODUCTION: Traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) are risk factors for early onset of Alzheimer's disease (AD) and may accelerate the progression rate of AD pathology. As amyloid-beta (A β) plaques are a hallmark of AD pa... (Source: SafetyLit)
Source: SafetyLit - July 19, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Women who have had 5 kids are 70% more likely to develop Alzheimer ’s
The study was carried out on a total of 3,549 women in South Korea and Greece, who were tracked from the age of 71. The findings were published in the journal Neurology. (Source: the Mail online | Health)
Source: the Mail online | Health - July 18, 2018 Category: Consumer Health News Source Type: news

Having 5 or more babies may increase Alzheimer's risk, study finds
Giving birth to five or more children may increase Alzheimer's risk by 70% in old age, according to a new study of women in Korea and Greece. (Source: CNN.com - Health)
Source: CNN.com - Health - July 18, 2018 Category: Consumer Health News Source Type: news

Does a Woman's Childbearing History Affect Her Alzheimer's Risk?
WEDNESDAY, July 18, 2018 -- A woman's pregnancy history may predict her risk for developing Alzheimer's disease, new research suggests. " We found that women who had given birth to five or more children were 70 percent more likely to develop... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 18, 2018 Category: General Medicine Source Type: news

Proteomics studies on the basic biology of Alzheimer's, cancer and listeriosis
(American Society for Biochemistry and Molecular Biology) Recent articles in the journal Molecular& Cellular Proteomics investigate metabolic quirks of cancer cells, the effects of inhibiting the enzyme that generates amyloid beta, and the mechanism by which a bacterial toxin kills host cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 18, 2018 Category: International Medicine & Public Health Source Type: news

Bill Gates jump-starts research on test for Alzheimer's
Bill Gates joins a coalition of investors giving $30 million to find a "reliable, affordable" diagnostic test for Alzheimer's disease. (Source: CNN.com - Health)
Source: CNN.com - Health - July 17, 2018 Category: Consumer Health News Source Type: news

Military personnel show brain changes similar to those in retired football players suspected to have CTE
This study was supported by the Fran and Ray Stark Foundation Fund for Alzheimer ’s Disease Research; the Parlow-Solomon and Plot Professorships; Bob and Marion Wilson; the Ahmanson Foundation; the National Institutes of Health; and the Department of Energy.The FDDNP tracer is intellectual property owned by UCLA and licensed to TauMark LLC. Barrio, Huang, Omalu, Satyamurthy and Small are co-inventors of the marker. Barrio, Fitzsimmons, Huang, Satyamurthy and Small have a financial interest in TauMark. Other disclosures are listed in the study. (Source: UCLA Newsroom: Health Sciences)
Source: UCLA Newsroom: Health Sciences - July 17, 2018 Category: Universities & Medical Training Source Type: news

PET could make synaptic density an Alzheimer's biomarker
Researchers from Yale University are reporting promising results with a PET...Read more on AuntMinnie.comRelated Reading: Are amyloid PET scans ready for the clinical setting? PET links amyloid, vascular factors to cognitive decline PET with novel tracers foretells early Alzheimer's risk PiB-PET study strengthens link between amyloid, dementia High amyloid levels on PET may indicate early Alzheimer's (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 17, 2018 Category: Radiology Source Type: news

Bill Gates, Others Commit $30 Million to Fund Alzheimer's Test Bill Gates, Others Commit $30 Million to Fund Alzheimer's Test
Backed by Bill Gates and others, the Diagnostics Accelerator venture fund will provide grants to researchers working on novel biomarkers for early detection of Alzheimer's and related dementias.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 17, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

It ’s Nearly Impossible to Diagnose Alzheimer’s Disease in Living People. Bill Gates Wants to Change That
Name practically any disease or condition that afflicts the human body and there’s probably a good test for detecting it — preferably early, when there’s a chance that promising treatments can slow it down or even cure it. Cancer, inherited forms of heart disease, diabetes, hypertension, and even certain mental illnesses can be picked up by tracking hormones, genes or other things circulating in the body. But that hasn’t been the case with Alzheimer’s disease, the neurodegenerative condition that was first described in 1906, and more than a century later, still doesn’t have a blood test ...
Source: TIME: Health - July 17, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Disease healthytime onetime Source Type: news

Bill Gates backs $30 million push for early Alzheimer's diagnostics
Billionaire Bill Gates and Est ée Lauder Cos chairman emeritus Leonard Lauder on Tuesday said they will award $30 million over three years to encourage development of new tests for early detection of Alzheimer's disease. (Source: Reuters: Health)
Source: Reuters: Health - July 17, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Bill Gates Announces Further Investment In Alzheimer's Research, Taking On Disease Detection
Microsoft cofounder Bill Gates revealed more of his plan to invest in Alzheimer's disease research on Tuesday. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 17, 2018 Category: Pharmaceuticals Authors: Michela Tindera, Forbes Staff Source Type: news

Bill Gates jump-starts research for an affordable test for Alzheimer's
Bill Gates joins a coalition of investors giving $30 million to find a "reliable, affordable" diagnostic test for Alzheimer's disease. (Source: CNN.com - Health)
Source: CNN.com - Health - July 17, 2018 Category: Consumer Health News Source Type: news

Dementia and Alzheimer ’s Services @ Your Library
  On May 4, 2018, I was honored to lead a session entitled “Dementia and Alzheimer’s Services @ Your Library” for approximately 40 front line library staff members attending the annual Reaching Forward Conference sponsored by the Illinois Library Association.  In addition to demonstrating how NLM databases such as Medline Plus can provide much needed medical information for those living with dementia and their care partners, I was also able to share some of the knowledge about dementia that I learned during the decade that I cared for my late husband who had been diagnosed with a young onset dem...
Source: The Cornflower - July 17, 2018 Category: Databases & Libraries Authors: Miles Dietz-Castel Tags: Outreach Source Type: news

New Coalition of Philanthropists Including Bill Gates and Leonard Lauder Commit More Than $30 Million to Develop New Tools to Diagnose Alzheimer's Disease
Philanthropist Bill Gates and the Alzheimer's Drug Discovery Foundation (ADDF) co-founder Leonard Lauder have announced a new initiative, Diagnostics Accelerator, to develop novel biomarkers for the early detection of Alzheimer's disease and related dementias. (Source: eHealth News EU)
Source: eHealth News EU - July 17, 2018 Category: Information Technology Tags: Featured Industry Business and Industry Source Type: news

Preclinical PET sheds light on Parkinson's abnormalities
Data collected from preclinical PET scans of rhesus macaque monkeys eventually...Read more on AuntMinnie.comRelated Reading: PET imaging could help personalize cancer treatment Michael J. Fox Foundation launches $2M PET tracer prize FDG-PET predicts survival in Parkinsonian syndrome IDEAS study to explore amyloid PET and Alzheimer's PET imaging shows promise with Parkinson's (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 17, 2018 Category: Radiology Source Type: news

Novel Imaging Tracer May Have Promise in Alzheimer's (CME/CE)
(MedPage Today) -- PET scans targeting SV2A assess synaptic density, small study suggests (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - July 16, 2018 Category: Psychiatry Source Type: news

Genesis of Toxic Tau in Alzheimer's Disease Revealed Genesis of Toxic Tau in Alzheimer's Disease Revealed
New research provides novel insights into the shape-shifting nature of tau protein and suggests new avenues for Alzheimer's drug development.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - July 16, 2018 Category: Pathology Tags: Neurology & Neurosurgery News Source Type: news

Yale-developed test for Alzheimer ’s disease directly measures synaptic loss
A new method, developed and tested at Yale, directly measures loss of synapses in the area of the brain linked to memory loss. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 16, 2018 Category: Universities & Medical Training Source Type: news

Vitamin D No Panacea for Brain Diseases
MONDAY, July 16, 2018 -- Vitamin D does little to defend your brain against multiple sclerosis, Parkinson's disease or Alzheimer's disease, a new review shows. The finding is based on an analysis of more than 70 studies. " Our work counters an... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 16, 2018 Category: General Medicine Source Type: news

1 in 9 U.S. Adults Over 45 Reports Memory Problems
Title: 1 in 9 U.S. Adults Over 45 Reports Memory ProblemsCategory: Health NewsCreated: 7/13/2018 12:00:00 AMLast Editorial Review: 7/16/2018 12:00:00 AM (Source: MedicineNet Alzheimer)
Source: MedicineNet Alzheimer - July 16, 2018 Category: Geriatrics Source Type: news

Implications of unmet promise of a miracle drug for Alzheimer's disease
(Regenstrief Institute) In 'The Unmet Promise of a Miracle Drug for Alzheimer's Disease: Implications for Practice, Policy, and Research,' the authors lament the unmet promise of a miracle drug for Alzheimer disease but are heartened by what they see as encouraging improvements in care (care transformation) for a growing population of older adults, many with dementia. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 16, 2018 Category: International Medicine & Public Health Source Type: news

Yale-developed test for Alzheimer's disease directly measures synaptic loss
(Yale University) Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer's disease. The method, which uses PET imaging technology to scan for a specific protein in the brain linked to synapses, has the potential to accelerate research for new Alzheimer's treatments, the researchers said. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 16, 2018 Category: International Medicine & Public Health Source Type: news

Greg Kennedy honored with 2018 Alzheimer Award
(IOS Press) Amsterdam, NL, July 16, 2018 -- The Journal of Alzheimer's Disease (JAD) is pleased to announce that Greg Kennedy, a PhD candidate at the Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, Australia, has been chosen as the recipient of the 2018 Alzheimer Award. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2018 Category: International Medicine & Public Health Source Type: news

New development in 3D super-resolution imaging gives insight on Alzheimer's disease
(Purdue University) One major problem with understanding Alzheimer's is not being able to clearly see why the disease starts. A super-resolution 'nanoscope' developed by Purdue University researchers now provides a 3D view of brain molecules with 10 times greater detail. This imaging technique could help reveal how the disease progresses and where new treatments could intervene. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: Alzheimer's risk 10 times lower with herpes medication
New research offers 'the first population evidence for a causal link' between herpes infection and the development of Alzheimer's disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 15, 2018 Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news

Dementia - the best exercises to reduce Alzheimer’s symptoms revealed
DEMENTIA risk could be reduced by making changes to your diet or exercise plan. These are the best exercises to reduce the symptoms of Alzheimer ’s disease, according to charity the Alzheimer’s Society. (Source: Daily Express - Health)
Source: Daily Express - Health - July 13, 2018 Category: Consumer Health News Source Type: news

Higher Blood Pressure Has Links to Brain Lesions in Older Adults
In a longitudinal study, researchers find that elderly people with higher pressure were more likely to show signs of Alzheimer’s disease in brain tissue. (Source: The Scientist)
Source: The Scientist - July 13, 2018 Category: Science Tags: News & Opinion Source Type: news

Weekly Postings
See something of interest? Please share our postings with colleagues in your institutions! Spotlight The MAReport: Check out the Spring 2018 issue of the MAReport newsletter! This quarter, Executive Director Kate Flewelling talked about attending the All of Us launch event at the historic Abyssinian Baptist Church in Harlem, New York City. Call for Applicants for the Sewell Stipend to Attend the 2018 APHA Annual Meeting – Is your position related to public health? Would you like an opportunity to immerse yourself in the public health field for a few days? Apply for the Sewell Travel Award for Public Health and attend...
Source: NN/LM Middle Atlantic Region Blog - July 13, 2018 Category: Databases & Libraries Authors: Hannah Sinemus Tags: Weekly Postings Source Type: news

Impact of Late-Life Blood Pressure on the Brain Revealed Impact of Late-Life Blood Pressure on the Brain Revealed
Higher late-life systolic blood pressure has been tied to more brain infarcts and more hallmarks of Alzheimer's disease, specifically neurofibrillary tangles, results of a novel autopsy study show.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 13, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

The secret sulfate code that lets the bad Tau in
(American Society for Biochemistry and Molecular Biology) Researchers at the UT Southwestern Medical Center have uncovered details of how cells invite inside corrupted proteins that can turn normal proteins corrupt, leading to neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. Understanding the molecular details of how these proteins spread from cell to cell could lead to therapies to halt disease progression. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2018 Category: International Medicine & Public Health Source Type: news

New research effort to understand role of APOE mutation in Alzheimer's disease
(Jackson Laboratory) Inheriting a specific genetic variant, APOEε4, is linked with 15-20 percent percent rise in risk of developing Alzheimer's, with at least 20 other genes implicated. The National Institute on Aging awarded a five-year grant totaling $4.2 million to Jackson Lab to study how APOEε4 risk depends on other genes, in mice with a wide variety of genetic backgrounds. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2018 Category: International Medicine & Public Health Source Type: news

Native state is fortunate trap in the journey of protein to its destination, fibril state
(Bentham Science Publishers) Arranging into well-organized fibrillar aggregate, commonly known as amyloid fibril is an inherent property of any polypeptide chain. Amyloid fibrils are associated with a number of severe human pathologies like the Alzheimer's disease, Parkinson's disease, type 2 diabetes and many more. This review article includes the recent studies of identification and characterization of possible conformations of proteins which can act as aggregation precursor state (APS). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2018 Category: International Medicine & Public Health Source Type: news

High blood pressure may threaten the aging brain
New research suggests that high blood pressure ​ later in life may contribute to blood vessel blockages and tangles linked to Alzheimer's disease​ (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - July 12, 2018 Category: Consumer Health News Source Type: news

Medical News Today: Vitamin D offers no protection against Alzheimer's
Systematic review of clinical studies finds no robust evidence that vitamin D protects the brain against diseases such as Alzheimer's, MS, and Parkinson's. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 12, 2018 Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news

Vitamin D offers no protection against Alzheimer's
Systematic review of clinical studies finds no robust evidence that vitamin D protects the brain against diseases such as Alzheimer's, MS, and Parkinson's. (Source: Parkinson's Disease News From Medical News Today)
Source: Parkinson's Disease News From Medical News Today - July 12, 2018 Category: Neurology Tags: Alzheimer's / Dementia Source Type: news

Assessing wandering risk among individuals with Alzheimer's disease and dementia: a pilot study - Barnard-Brak L, Richman DM, Owen DC.
We examined a screening instrument to assess risk for wandering among individuals with Alzheimer's disease and dementia according to caregiver informants. METHODS: Pilot data were collected on the Risk of Wandering (RoW) screening instr... (Source: SafetyLit)
Source: SafetyLit - July 12, 2018 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

A look at the $14 million in Louisville health care projects approved by the state
Kentucky's Division of Certificate of Need has given approval five projects that could bring millions in potential health care development in Louisville, according to its most recent newsletter. In total, estimated costs for the projects are about $14.7 million — the largest of which is a new $13.2 million, 64-bed personal care facility at 4922 Brownsboro Road for seniors with Alzheimer's disease and other forms of dementia. Virginia-based senior-care company Artis Senior Living LLC i s building… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 12, 2018 Category: Pharmaceuticals Authors: Chris Larson Source Type: news

Medical News Today: High blood pressure may increase dementia risk
A new study looking at links between hypertension in later life and brain health finds an increased risk of Alzheimer's hallmarks and brain lesions. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 12, 2018 Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news

New study highlights Alzheimer's herpes link, experts say
(University of Manchester) A new commentary by scientists at the Universities of Manchester and Edinburgh on a study by Taiwanese epidemiologists supports the viability of a potential way to reduce the risk of Alzheimer's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 12, 2018 Category: International Medicine & Public Health Source Type: news

Study: High Blood Pressure Threatens Aging Brain
Older people with high systolic blood pressure readings (the top number) had higher risks of having blood vessel blockages in the brain and tangles linked to Alzheimer's disease, researchers found in a study that tracked more than 1,300 people until they died. (Source: WebMD Health)
Source: WebMD Health - July 11, 2018 Category: Consumer Health News Source Type: news

Blood pressure linked to Alzheimer's: Higher than average reading raises risk by 46%, study warns
Scientists from Rush Alzheimer ’s Disease Center in Chicago found a link between high blood pressure and brain tangles, but taking blood pressure medications did not make any difference. (Source: the Mail online | Health)
Source: the Mail online | Health - July 11, 2018 Category: Consumer Health News Source Type: news

This Surprising Factor May Raise Your Risk of Alzheimer ’s
Outside of your genetic makeup, few things are definitively linked to Alzheimer’s disease and other degenerative brain conditions. Unlike heart disease, which is affected by behaviors like diet, exercise and smoking, science hasn’t documented many risk factors that make the brain more vulnerable to dementia—although there are hints that things like physical activity and brain games might help to protect against cognitive decline. But in a study published in the journal Neurology, researchers led by Dr. Zoe Arvanitakis, medical director of the Rush Memory Clinic at Rush Alzheimer’s Disease Center, fi...
Source: TIME: Health - July 11, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Alzheimer's Blood Pressure Brain healthytime Heart Disease Source Type: news

Blood pressure linked to lesions, signs of Alzheimer's in autopsied brains
Older people with higher-than-average blood pressure have more markers of brain disease than their average-pressure peers, according to a study published Wednesday in the journal Neurology. In particular, the researchers saw increased signs of brain infarcts, or areas of dead tissue caused by a block in the blood supply to the brain, when looking at postmortem tissue under a microscope. (Source: CNN.com - Health)
Source: CNN.com - Health - July 11, 2018 Category: Consumer Health News Source Type: news

High Blood Pressure Threatens Aging Brain, Study Says
WEDNESDAY, July 11, 2018 -- Here's yet another reason to get your blood pressure under control: High blood pressure later in life may contribute to blood vessel blockages and tangles linked to Alzheimer's disease, new research suggests. Tracking... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 11, 2018 Category: General Medicine Source Type: news

Dementia: assessment, management and support for people living with dementia and their carers
This guideline covers diagnosing and managing dementia (including Alzheimer's disease). It aims to improve care by making recommendations on training staff and helping carers to support people living with dementia. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 11, 2018 Category: Consumer Health News Source Type: news

Morning Break: Suicide'Always an Option'; Dying Heart Revived; Alzheimer's Big Bang
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - July 11, 2018 Category: American Health Source Type: news