To Salt or Not to Salt?--That Is the Question in Cirrhosis To Salt or Not to Salt?--That Is the Question in Cirrhosis
Should patients with cirrhosis be on a salt-restricted diet? This review examines the role of sodium balance in cirrhosis, and weighs the pros and cons of dietary restriction.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 2, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Shear-wave elastography works to evaluate liver disease
Two-dimensional shear-wave elastography is an effective tool for identifying...Read more on AuntMinnie.comRelated Reading: AIUM: Can deep learning classify liver fibrosis on US? Adding blood test to US improves liver cancer diagnosis How accurate are SRU guidelines for advanced fibrosis? Spleen stiffness correlates with cirrhosis complication Quantitative ultrasound method stages fatty liver (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 30, 2018 Category: Radiology Source Type: news

D.C. Rap Up: Smallpox Rx; Essure Goes Away; Cirrhosis Deaths Spike
(MedPage Today) -- MedPage Today's weekly summary of policy news gets a hip-hop reboot from Cleavon Gilman, MD (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - July 23, 2018 Category: OBGYN Source Type: news

America ’s Drinking Habits Are Killing More Young People, Study Suggests
Liver disease deaths are growing more common in the U.S. and disproportionately affecting younger Americans, according to a recent study. The paper, published in The BMJ just a day after a Centers for Disease Control and Prevention (CDC) report on rising liver cancer death rates, paints a troubling picture of how Americans’ drinking habits may be affecting their health. While the new study couldn’t prove causation, the researchers say drinking is likely to blame for the growing number of adults aged 24 to 35 who are dying from cirrhosis, or scarring of the liver. The researchers used deaths logged in the CDC&r...
Source: TIME: Health - July 21, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime Research Source Type: news

Liver disease deaths skyrocket among young adults
Deaths caused by liver disease are up dramatically and young adults were the hardest hit. A new study, published in the British Medical Journal, said cirrhosis-related deaths increased by 65 percent from 1999 to 2016, and deaths from liver cancer doubled, The Washington Post reported. The rise in death rates was driven predominantly by alcohol-induced disease, the study said. People aged 25 to 34 had the highest increase in cirrhosis deaths among the demographic groups studied, averaging a 10.5… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 20, 2018 Category: Pharmaceuticals Authors: Anne Stych Source Type: news

Liver disease deaths spike among young Americans
More Americans, especially young people, are dying of conditions related to liver cirrhosis, according to a new study. (Source: CNN.com - Health)
Source: CNN.com - Health - July 19, 2018 Category: Consumer Health News Source Type: news

240% spike in young adults dying of alcohol-related liver disease
A new study from the University of Michigan Medicine has found that alcohol is fueling a rise in young adults dying from cirrhosis, or liver scarring, increasing by 65 percent between 1999 and 2016. (Source: the Mail online | Health)
Source: the Mail online | Health - July 19, 2018 Category: Consumer Health News Source Type: news

Patients with compensated cirrhosis are also at risk of falling - Rom án E, Gely C, Flavià M, Poca M, Alvarado E, Vargas V, Guarner C, Soriano G.
Some years ago, we observed that falling in the previous year was more frequent in patients with cirrhosis than in healthy controls, and showed for the first time that cirrhotic patients, mainly those with cognitive dysfunction, are predisposed to falling ... (Source: SafetyLit)
Source: SafetyLit - July 19, 2018 Category: International Medicine & Public Health Tags: Falls Source Type: news

Young Adults Are Drinking Themselves To Death, Study Finds
ANN ARBOR, Mich. (CBS Local) – A disturbing new study declares that a growing number of young Americans are drinking themselves to death. The findings point to a skyrocketing increase in cirrhosis and liver cancer deaths over the last decade. According to the report published in the journal BMJ, deaths due to cirrhosis increased by 65 percent from 2009 to 2016. Deaths from liver cancer doubled (from more than 5,100 to nearly 11,100) during the same time period. Americans between 25-34 were found to be the largest group affected. Cirrhosis is a disease commonly caused by excessive drinking or ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 19, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Alcohol Drinking liver disease Local TV talkers Source Type: news

Liver Disease-Related Deaths Up Sharply From 1999 to 2016
THURSDAY, July 19, 2018 -- Liver disease-related deaths, particularly due to cirrhosis, have been increasing in the United States since 2009, according to a study published online July 18 in The BMJ. Elliot B Tapper, M.D., and Neehar D Parikh, M.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 19, 2018 Category: Pharmaceuticals Source Type: news

Deaths by alcohol-related liver disease skyrocket among young adults, U.S. study shows
Cirrhosis deaths among people 25 to 34 years old rose 10.5 per cent between 2009 and 2016 in the U.S., according to new data. (Source: CBC | Health)
Source: CBC | Health - July 19, 2018 Category: Consumer Health News Tags: News/Health Source Type: news

U.S. Deaths From Liver Disease Rising Rapidly
A growing number of Americans are dying from liver disease and liver cancer.The increase among 25- to 34-year-olds is especially troubling because the deaths are due to cirrhosis, a disease caused by excessive drinking, the authors of a new study said. The researchers suspect the economic downturn in 2008 prompted people to comfort themselves with alcohol. (Source: WebMD Health)
Source: WebMD Health - July 19, 2018 Category: Consumer Health News Source Type: news

Cirrhosis Deaths Spiked 1999-2016
(MedPage Today) -- Another study finds worrisome trends (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - July 19, 2018 Category: American Health Source Type: news

HCV Eradication by DAAs Improves Glucose Tolerance HCV Eradication by DAAs Improves Glucose Tolerance
Chronic HCV genotype 1 is associated with a higher incidence of type 2 diabetes in its advanced stages. Could early HCV eradication improve glucose tolerance in patients with HCV-related cirrhosis?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 19, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Take a Number: More Americans Are Dying of Cirrhosis and Liver Cancer
Death rates from both diseases have risen sharply, particularly among young adults over the last decade. A possible villain: the Great Recession. (Source: NYT Health)
Source: NYT Health - July 18, 2018 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Liver Cirrhosis Liver Cancer Alcoholic Beverages Deaths (Fatalities) BMJ (Journal) United States Source Type: news

Liver disease: Five early symptoms of organ damage caused by too much alcohol
LIVER disease is often caused by drinking too much alcohol. If the misuse of alcohol continues, it can lead to a condition called alcohols-related cirrhosis and serious complications can occur. The early stages of the organ damage can be reversed, so what are the early signs to watch out for? (Source: Daily Express - Health)
Source: Daily Express - Health - July 18, 2018 Category: Consumer Health News Source Type: news

TGen-led study shows DNA methylation related to liver disease among obese patients
(The Translational Genomics Research Institute) A TGen-led team has identified how DNA methylation is associated with a condition known as non-alcoholic fatty liver disease (NAFLD), which can lead to liver cirrhosis and death, and is one of the leading indicators for liver transplants. In one of the most exacting studies of its kind, TGen scientists found evidence that DNA methylation has a role in the initiation of NAFLD-related fibrosis, according to a study published in the journal Clinical Epigenetics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 18, 2018 Category: International Medicine & Public Health Source Type: news

Liver Cancer Death Rate In US Surged 43% In 16 Years
(CNN) — Death rates from liver cancer increased 43% for American adults from 2000 to 2016, according to a report released Tuesday by the US Centers for Disease Control and Prevention’s National Center for Health Statistics. The increase comes even as mortality for all cancers combined has declined. Liver cancer death rates increased for both men and women 25 and older, as well as white, black and Hispanic people. Only Asians and Pacific Islanders saw a decrease in mortality from liver cancer. The rise in mortality doesn’t mean that liver cancer is deadlier than before, according to Dr. Jiaquan Xu, the aut...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 17, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Cancer Liver Cancer Source Type: news

Alcoholic liver disease: Take this many hours off drinking a week to slash your risk
ALCOHOLIC liver disease is a problem caused by drinking too much alcohol, but symptoms usually only show when the organ has been severely damaged. It ’s important to recognise these signs as repeated damage can lead to cirrhosis - permanent scarring of the liver. One way to avoid the condition developing in the first place is to avoid drinking regularly. You should also have a certain time off drinking a week to allow your liver to recover. (Source: Daily Express - Health)
Source: Daily Express - Health - July 4, 2018 Category: Consumer Health News Source Type: news

Liver damage: Drinking this much alcohol a day can lead to organ failure
LIVER damage, or liver disease as it ’s also referred, is commonly caused by obesity, an undiagnosed hepatitis infection and alcohol misuse. Drinking too much alcohol can lead to a condition called alcohol-relate cirrhosis and serious complications can occur. But what counts as excessive drinking and what’s the recommended number o f units of alcohol that should be consumed in a day? (Source: Daily Express - Health)
Source: Daily Express - Health - July 2, 2018 Category: Consumer Health News Source Type: news

A flavonoid in fruits and vegetables found to prevent hepatitis B
(Natural News) Naringenin is a dietary flavonoid present in many fruits, herbs, and vegetables. Taiwanese researchers believe this phytochemical can stop the hepatitis B virus (HBV) from causing hepatitis, liver cirrhosis, and liver cancer. The virus spreads by infecting the host DNA with the HBV X protein (HBx). Even as the liver heals following every instance of... (Source: NaturalNews.com)
Source: NaturalNews.com - June 29, 2018 Category: Consumer Health News Source Type: news

Liver disease symptoms: Two toilet habits that could indicate you have severe organ damage
LIVER disease symptoms, caused by excessive alcohol intake, usually only show when the organ has been severely damaged. Cirrhosis is the name given to scarring of the liver caused by long-term liver damage. There are two signs linked to your toilet habits that can indicate this. (Source: Daily Express - Health)
Source: Daily Express - Health - June 28, 2018 Category: Consumer Health News Source Type: news

Follow-up of Patients With HCV, Liver Disease After DAAs Follow-up of Patients With HCV, Liver Disease After DAAs
This study evaluated the long-term success of viral eradication in patients with advanced fibrosis or cirrhosis treated with DAAs.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 28, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Liver disease symptoms: Seven signs your organ has been severely damaged by alcohol
LIVER disease symptoms, caused by excessive alcohol intake, usually only show when the organ has been severely damaged. It ’s important to recognise these signs as repeated damage can lead to alcoholic liver cirrhosis. There are seven symptoms to look out for. (Source: Daily Express - Health)
Source: Daily Express - Health - June 19, 2018 Category: Consumer Health News Source Type: news

Researchers find a promising new approach for treating liver cirrhosis
(Elsevier) In a study in The American Journal of Pathology, investigators report that treatment with aleglitazar, a dual peroxisome proliferator-activated receptor-alpha/gamma (PPARα/γ) agonist, reduced inflammation, vasoconstriction, angiogenesis, mucosal disruption, and tumor necrosis factor (TNF)-α overproduction in cirrhotic rats with PH. This suggests a promising new approach for treating liver cirrhosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Chronic Viral Hepatitis, Alcoholism, Cirrhosis Linked to Liver Cancer
Title: Chronic Viral Hepatitis, Alcoholism, Cirrhosis Linked to Liver CancerCategory: Doctor's& Expert's views on SymptomsCreated: 10/31/2001 12:00:00 AMLast Editorial Review: 6/13/2018 2:55:10 PM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - June 13, 2018 Category: Cancer & Oncology Source Type: news

Liver Cancer Screening in At-Risk Patients Underused (CME/CE)
(MedPage Today) -- Cirrhosis patients, others not getting tested, study finds (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - June 6, 2018 Category: Hematology Source Type: news

Eating a Mediterranean-style diet protects your liver
(Natural News) If you want a healthy liver and gut, an article on EurekAlert! recommended taking up a Mediterranean-style diet. A study on American and Turkish patients with liver cirrhosis showed that eating fermented milk products and vegetables – plus moderate amounts of chocolate, coffee, and tea – could reduce the chances of serious complications that... (Source: NaturalNews.com)
Source: NaturalNews.com - May 9, 2018 Category: Consumer Health News Source Type: news

Shocking video reveals how alcohol wrecks your liver
Celebrity doctor Drew Pinsky, who hosts the show Dr Drew's Lifechangers in the US, tells two heavy-drinking twins how alcohol could give them cirrhosis and one day kill them. (Source: the Mail online | Health)
Source: the Mail online | Health - May 9, 2018 Category: Consumer Health News Source Type: news

Study: Alcohol-related cirrhosis patients are sicker, costlier and often female
(Michigan Medicine - University of Michigan) A new review by Michigan Medicine finds that women drinkers are disproportionately affected in alcohol-related cirrhosis cases. Why -- and what's next. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 7, 2018 Category: International Medicine & Public Health Source Type: news

CBCT-guided radiotherapy shows promise for HCC
A novel radiotherapy technique using conebeam CT (CBCT) shows promise as a...Read more on AuntMinnie.comRelated Reading: Adding blood test to US improves liver cancer diagnosis Contrast US clears up indeterminate HCC cases on MRI US surveillance of HCC subject to image quality issues HCC screening boosts survival rate in cirrhosis patients Dual-tracer PET/CT helps pick patients for liver transplant (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 24, 2018 Category: Radiology Source Type: news

What Causes Hyponatremia?
Discussion Normal kidneys regulate water balance to maintain a plasma osmolality of 275-290 mOsm/kg normally. Thirst and arginine vasopressin or antidiuretic hormone (ADH) are the primary regulators of plasma osmolality. ADH is made in the hypothalamus and released by the posterior pituitary gland. ADH acts on the kidney’s distal collecting duct to increase water reabsorption. ADH is appropriately released in hypovolemic states, such as dehydration caused by gastroenteritis. ADH has an ~10 minute half-life and therefore can respond to rapid changes in volume status. Sodium balance is regulated by aldosterone (as part...
Source: PediatricEducation.org - April 23, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Unlocking the Potential of AI For Fatty Liver Treatments
ReviveMed, a Massachusetts Institute of Technology (MIT) spinout, is using artificial intelligence (AI) to unlock the power of metabolomics to discover new therapies to treat diseases. Metabolomics is the large-scale study of small molecules like glucose or cholesterol produced by cellular activity. ReviveMed’s platform could help pharmaceutical companies redesign existing drugs or develop new drugs to help patients suffering from disease. The Cambridge, MA-based company recently raised funding to help further develop its AI solution, closing an oversubscribed seed round of $1.5 million. Rivas Capital led the round, ...
Source: MDDI - April 19, 2018 Category: Medical Devices Authors: Omar Ford Tags: Software Source Type: news

OBV/PTV/r+DSV+RBV in Patients With HCV Cirrhosis OBV/PTV/r+DSV+RBV in Patients With HCV Cirrhosis
Does real-life data confirm the results of clinical trials regarding the efficacy and safety profile of this DAA regimen in patients with HCV infection and cirrhosis?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 19, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Liver Transplant in Patients With Alcoholic Liver Disease Liver Transplant in Patients With Alcoholic Liver Disease
Some transplant centers are reluctant to perform liver transplants in patients with alcoholic liver disease. Do these patients have worse outcomes than those transplanted for viral cirrhosis?Alcohol and Alcoholism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 17, 2018 Category: Consumer Health News Tags: Transplantation Journal Article Source Type: news

Costs Balloon after Cirrhosis Diagnosis for NAFLD/NASH (CME/CE)
(MedPage Today) -- Experts say study emphasizes importance of identifying patients early (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 16, 2018 Category: Primary Care Source Type: news

A Mediterranean diet may boost the health of the liver
Adopting the diet, loaded with fruit and veg, whole grains, olive oil and fish, lowers the risk of hospitalisation in patients with cirrhosis, experts at Virginia Commonwealth University found. (Source: the Mail online | Health)
Source: the Mail online | Health - April 16, 2018 Category: Consumer Health News Source Type: news

Difficult-to-Treat Sclerosing Cholangitis Eased With Statins Difficult-to-Treat Sclerosing Cholangitis Eased With Statins
Primary sclerosing cholangitis is progressive, and there is no known therapy to prevent cirrhosis, liver transplant, or progression to cancer, but a new investigation suggests statins might help.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 13, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Germany: compensated cirrhosis substantially increases comorbidities and healthcare costs for patients with non-alcoholic fatty liver disease/non-alcoholic steatohepatitis
(European Association for the Study of the Liver) Compensated cirrhosis substantially increases comorbidities and healthcare costs for patients with non-alcoholic fatty liver disease/non-alcoholic steatohepatitis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2018 Category: International Medicine & Public Health Source Type: news

Long-term obeticholic acid treatment leads to reversal or stabilization of fibrosis/cirrhosis in patients with PBC
(European Association for the Study of the Liver) After three years of treatment with obeticholic acid, 85 percent of patients with PBC and an incomplete response to UDCA experienced stabilization or regression of fibrosis/cirrhosis in the POISE biopsy sub-study. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2018 Category: International Medicine & Public Health Source Type: news

' Alarming' New Numbers on Bacterial Infection in Cirrhosis'Alarming' New Numbers on Bacterial Infection in Cirrhosis
One-third of infections in cirrhotic patients around the world are caused by multidrug-resistant organisms, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 12, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Many Cirrhosis Patients Harbor Multidrug-Resistant Bugs (CME/CE)
(MedPage Today) -- 18% of North Americans with infections; three-quarters of those in India (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - April 12, 2018 Category: American Health Source Type: news

Non-profit ’s $300 hepatitis C cure as effective as $84,000 alternative
Exclusive: 71 million people stand to benefit from reduced price treatment for virus which can lead to liver cirrhosis, cancer and deathAn affordable hepatitis C treatment has been shown to be safe and effective, with very high cure rates for patients including hard-to-treat cases, in interim clinical trial results that offer hope to the 71 million people living with the disease worldwide. The treatment is expected to cost $300 for 12 weeks, or $3.50 per day, in Malaysia, where trials were conducted along with Thailand – a fraction of the cost of other hepatitis C medicines produced by major drugmakers, which often r...
Source: Guardian Unlimited Science - April 12, 2018 Category: Science Authors: Julia Kollewe Tags: Medical research Hepatitis C Global health Global development Science Society Egypt Pharmaceuticals industry Source Type: news

Sensitive new assay detects hepatitis B infection in single liver cells and serum
(Elsevier) Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples. This assay can be used to diagnose HCC at an earlier stage to manage treatment more effectively. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 12, 2018 Category: International Medicine & Public Health Source Type: news

A third of bacterial infections in patients with cirrhosis across the world are multi-drug resistant
(European Association for the Study of the Liver) An international study reports a high prevalence of multi-drug-resistant bacteria in hospitalized patients with cirrhosis and significant regional differences in risk. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 12, 2018 Category: Biology Source Type: news

Mediterranean-style diet improves gut microbial diversity and reduces hospitalization
(European Association for the Study of the Liver) ILC 2018: Diets rich in vegetables, fermented milk products, tea, coffee and chocolate may improve outcomes in patients with liver cirrhosis. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 12, 2018 Category: Biology Source Type: news

Screening for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis achieving sustained virological response is likely to be cost effective
(European Association for the Study of the Liver) A Canadian study suggests that biannual or annual ultrasound screening for HCC is likely to be cost effective after a sustained virological response in those with hepatitis C-related cirrhosis, but not in those with advanced fibrosis without cirrhosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 12, 2018 Category: Cancer & Oncology Source Type: news

Scotland: Direct-acting antiviral agent therapy reduces the burden of HCV-related decompensated cirrhosis
(European Association for the Study of the Liver) National surveillance data and cost-effectiveness modeling provide complementary evidence to support the scale-up of DAA therapy in Scotland. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 12, 2018 Category: Infectious Diseases Source Type: news

Punjab, India: Mass treatment of a population with chronic hepatitis C infection produces high rates of cure
(European Association for the Study of the Liver) A program of decentralized public healthcare achieves high rates of cure regardless of genotype or the presence of cirrhosis: the Punjab Model. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 12, 2018 Category: Infectious Diseases Source Type: news