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Report suggests association between coffee and up to 70 percent reduced risk of liver disease
(Kaizo) A new roundtable report from the Institute for Scientific Information on Coffee (ISIC) in association with the British Liver Trust, on 'Looking after the liver: coffee, caffeine and lifestyle factors' highlights the potential role of coffee consumption in reducing the risk of liver diseases such as liver cancer and cirrhosis, with some studies reporting risk reduction of up to 70% (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 16, 2017 Category: Cancer & Oncology Source Type: news

US elastography for liver evaluation: Worth the cost?
Ultrasound elastography is a relatively new technology that can noninvasively...Read more on AuntMinnie.comRelated Reading: Elastography, color Doppler US avoid breast biopsies Elastography can help evaluate carotid plaque Shear-wave elastography spots Achilles tendinopathy Spleen stiffness correlates with cirrhosis complication Elastography aids assessment of focal prostate lesions (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 13, 2017 Category: Radiology Source Type: news

Statins, Decompensation, and Death in Alcoholic Cirrhosis Statins, Decompensation, and Death in Alcoholic Cirrhosis
Does regular use of statins improve outcomes and reduce mortality in patients with alcoholic cirrhosis?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 9, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

New study identifies targets to lessen the effects of alcoholic liver disease
(Elsevier) Chronic alcohol consumption causes abnormal fat accumulation in liver cells (steatosis) and liver fibrosis, which can lead to hepatitis, cirrhosis, and sometimes liver cancer. A new study in The American Journal of Pathology offers insights into the cellular aging that may trigger excessive fibrosis formation in the liver as well as possible means to inhibit these changes, which may lead to new therapeutic approaches for patients with ALD. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 8, 2017 Category: Biology Source Type: news

Living with NASH: An Unexpected Diagnosis
As our waistlines thicken and our activity levels decrease, another chronic illness threatens to disturb our comfortable lifestyles. And, because it ’s relatively unknown, diagnosis comes as a shock to patients, who usually associate liver disease with heavy consumption of alcohol.Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD), where fat accumulates in the liver. It is most commonly associated with obesity, insulin resistance, metabolic syndrome and/or genetic polymorphisms, and is aggravated by inflammation and fibrosis.  First identified in the 1980s, its ...
Source: EyeForPharma - November 3, 2017 Category: Pharmaceuticals Authors: Mariel Metcalfe Source Type: news

Mortality Rates for Overdose Patients Who Refuse Transport
This study was published March 28, 2016. The data obtained was from 2011-2013. Oh, how quickly things change in the drug trade. The Centers for Disease Control (CDC) reported the number of opioid-related deaths in 2014 was a 9% increase from the previous year.1 The illegal drug trade changes every day. More potent forms of opioids are being manufactured, and with that, more deaths occur. (Source: JEMS Patient Care)
Source: JEMS Patient Care - November 2, 2017 Category: Emergency Medicine Authors: Keith Wesley, MD, FACEP, FAEMS Tags: Patient Care Columns Source Type: news

The importance of addressing poor nutrition in patients with liver failure
(Wiley) Poor nutrition is common in patients with liver failure, or cirrhosis, and it can lead to muscle wasting, weakness, fatigue, and worse outcomes before and after patients undergo liver transplantation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 26, 2017 Category: International Medicine & Public Health Source Type: news

Burden of Cirrhosis Higher with Alcoholism (CME/CE)
(MedPage Today) -- One-third of patients account for half of cirrhosis costs (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 23, 2017 Category: Gastroenterology Source Type: news

Can Aspirin Stop Liver Cancer in Hepatitis B Patients?
FRIDAY, Oct. 20, 2017 -- Daily aspirin may reduce the risk of liver cancer for people with hepatitis B infection, a new study suggests. Hepatitis B virus attacks the liver and can cause cirrhosis and liver cancer. Previous research suggests daily... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 20, 2017 Category: General Medicine Source Type: news

Visceral Adipose Tissue Index IDs Risk of HCC in Cirrhosis
High VATI is also linked to risk of HCC recurrence in males with HCC who underwent liver transplant (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 18, 2017 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Internal Medicine, Oncology, Pathology, Journal, Source Type: news

Ethiopia: Sustaining HBV Intervention Success Stories
[Ethiopian Herald] Viral hepatitis result in a potentially life-threatening inflammation of the liver, which is characterized by complications of liver disease. Specifically, hepatitis B (HBV) and C (HCV) viruses alone cause chronic viral hepatitis which is a major global health problem responsible for 57_per cent of liver cirrhosis and 75_per cent of primary liver cancer cases, respectively. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 11, 2017 Category: African Health Source Type: news

Worse than liquor for your liver
Most people think liver disease only happens to alcoholics. But the truth is that being overweight or obese actually puts you at a much higher risk for liver damage than alcohol. In fact, alcohol contributes to only 6% of liver damage. But obesity contributes to 52% of liver disease. And if you’re obese, you’re 400% more likely to develop liver damage than a normal-weight individual.1 That’s why about 30% of people in America have some form of chronic fatty liver disease. It’s called non-alcoholic fatty liver disease (NAFLD). NAFLD causes painful swelling and scarring of the liver.  And I blame...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Health Weight Loss Source Type: news

Raised serum lactate in a cirrhotic patient presenting after a trivial fall - Ayeko OM, Barrow J, Ayeko MO.
We present the case of a pelvic fracture in a 69-year-old man with Child-Pugh class C cirrhosis who presented to the Accident and Emergency department after a slip on wet grass. After initially being systemically well, he became haemodynamically unstable i... (Source: SafetyLit)
Source: SafetyLit - October 4, 2017 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

QuickStats: Death Rates for Chronic Liver Disease and Cirrhosis, by Sex and Age Group — National Vital Statistics System, United States, 2000 and 2015
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - September 28, 2017 Category: American Health Source Type: news

Three or more cups of coffee daily halves mortality risk in patients with both HIV and HCV
(Elsevier) Patients infected by both HIV and hepatitis C virus are at specific risk of end-stage liver disease and greater risk of cardiovascular diseases and cancer. In addition, HIV infection accelerates the progression of chronic hepatitis C to fibrosis and development of cirrhosis and end-stage liver disease. In these HIV-HCV co-infected patients, drinking at least three cups of coffee each day halved the risk of all-cause mortality according to a new study published in the Journal of Hepatology. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 25, 2017 Category: Infectious Diseases Source Type: news

Statin Use Tied to Lower Mortality in Alcoholic Cirrhosis Statin Use Tied to Lower Mortality in Alcoholic Cirrhosis
Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 20, 2017 Category: Gastroenterology Tags: Diabetes & Endocrinology News Source Type: news

Is There a Standard for Surgical Therapy of HCC? Is There a Standard for Surgical Therapy of HCC?
This study compared different guidelines regarding indication for resection and transplantation in patients with hepatocellular carcinoma, with and without underlying cirrhosis. Is there a consensus?BMJ Open Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 13, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Drinks industry accused of downplaying 'alcohol-cancer risk'
Conclusion This qualitative analysis aimed to determine the accuracy of health information circulated by the alcohol industry on the links between alcohol and cancer. It found the industry and affiliated organisations use three main approaches: denial of the link between alcohol and cancer misinterpretation of the risk distraction by focusing on other risk factors This analysis highlights how these strategies could be detrimental to public health. Of course, it's possible, given this data was collected in 2016, that some of the websites and documents analysed by the researchers have since been updated. Regardless, the...
Source: NHS News Feed - September 8, 2017 Category: Consumer Health News Tags: Cancer Source Type: news

Statins slash the risk of death from cirrhosis by half
Researchers from the University Hospital of Hvidovre in Denmark found statins reduce the risk of dying from the alcohol-related disorder by 43 per cent but doctors are reluctant to prescribe them. (Source: the Mail online | Health)
Source: the Mail online | Health - September 7, 2017 Category: Consumer Health News Source Type: news

Alcoholic Cirrhosis Linked to Increased Admissions, Costs
Compared with non - alcoholic cirrhosis, excess 30 - day readmissions total 29.2 per 100 patients (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - September 1, 2017 Category: Psychiatry Tags: Family Medicine, Geriatrics, Gastroenterology, Internal Medicine, Critical Care, Nursing, Pathology, Psychiatry, Journal, Source Type: news

Cirrhosis
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - August 31, 2017 Category: General Medicine Source Type: news

Shorter Anti-HCV Regimen Effective in Patients With or Without Cirrhosis Shorter Anti-HCV Regimen Effective in Patients With or Without Cirrhosis
An eight-week regimen containing grazoprevir-ruzasvir-uprifosbuvir appears to be effective for treating hepatitis C virus (HCV) infection in patients with or without cirrhosis, according to findings from a pair of randomized phase 2 open-label trials.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 21, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Alcohol warning: THIS trendy spice can protect you from liver disease caused by drinking
ALCOHOL consumed in large amounts is the main cause in the Western world of liver disease, which includes fatty liver, alcoholic hepatitis, and chronic hepatitis with liver fibrosis or cirrhosis. However, a popular spice may provide a beneficial effect if you ’ve overdone the drinking. (Source: Daily Express - Health)
Source: Daily Express - Health - August 15, 2017 Category: Consumer Health News Source Type: news

TRIF-dependent Toll-like receptor signaling suppresses Scd1 transcription in hepatocytes and prevents diet-induced hepatic steatosis
Nonalcoholic fatty liver disease (NAFLD) includes a spectrum of diseases that ranges in severity from hepatic steatosis to steatohepatitis, the latter of which is a major predisposing factor for liver cirrhosis and cancer. Toll-like receptor (TLR) signaling, which is critical for innate immunity, is generally believed to aggravate disease progression by inducing inflammation. Unexpectedly, we found that deficiency in TIR domain–containing adaptor-inducing interferon-β (TRIF), a cytosolic adaptor that transduces some TLR signals, worsened hepatic steatosis induced by a high-fat diet (HFD) and that such exacerbati...
Source: Signal Transduction Knowledge Environment - August 8, 2017 Category: Science Authors: Chen, J., Li, J., Yiu, J. H. C., Lam, J. K. W., Wong, C.-M., Dorweiler, B., Xu, A., Woo, C. W. Tags: STKE Research Articles Source Type: news

FDA OKs 8-Week Mavyret for Hepatitis C FDA OKs 8-Week Mavyret for Hepatitis C
Glecaprevir/pibrentasvir is the first HCV treatment of this duration approved for genotypes 1 through 6 in previously untreated adults without cirrhosis.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 3, 2017 Category: Consumer Health News Tags: Gastroenterology News Alert Source Type: news

FDA Approves Mavyret (glecaprevir and pibrentasvir) for Hepatitis C
August 3, 2017 -- The U.S. Food and Drug Administration today approved Mavyret (glecaprevir and pibrentasvir) to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis, including... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

FDA approves Mavyret for Hepatitis C
The U.S. Food and Drug Administration today approved Mavyret (glecaprevir and pibrentasvir) to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis, including patients with moderate to severe kidney disease and those who are on dialysis. Mavyret is also approved for adult patients with HCV genotype 1 infection who have been previously treated with a regimen either containing an NS5A inhibitor or an NS3/4A protease inhibitor but not both. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 3, 2017 Category: American Health Source Type: news

GI Bleeding in Cirrhosis Patients With CAD and Cardiac Stents GI Bleeding in Cirrhosis Patients With CAD and Cardiac Stents
Cirrhotic patients often have varices and coagulopathy. Is it safe to treat these patients with dual antiplatelet therapy after cardiac stenting?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 3, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Gore touts reduced portal hypertension, complications in Viatorr Tips trial
W.L. Gore & Associates today released preliminary data from a trial of its Viatorr Tips endoprosthesis with controlled expansion, touting reduced portal hypertension treatment complications when compared to the company’s legacy Tips device and bare metal stents. Data from the study was presented at The International Liver Congress 2017 in Amsterdam, the Flagstaff, Ariz.-based company said. Preliminary data from the trial, which has 21 patients currently and is still enrolling, also indicated a reduction in hospital admissions from cirrhosis-related complications, including refractory ascites and sepsis, when the ...
Source: Mass Device - August 1, 2017 Category: Medical Devices Authors: Fink Densford Tags: Blood Management Clinical Trials Stent Grafts Stents Vascular W.L. Gore & Associates Source Type: news

Liver disease and alcohol: How YOU could find out if you have symptomless disease
LIVER disease and cirrhosis - can increase the risk of cancer and can be caused by drinking too much alcohol. (Source: Daily Express - Health)
Source: Daily Express - Health - July 31, 2017 Category: Consumer Health News Source Type: news

Combo Tx Fares Well in HIV-Positive Patients with HCV (CME/CE)
(MedPage Today) -- Sustained response in all HIV-positive patients without cirrhosis (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - July 26, 2017 Category: Consumer Health News Source Type: news

FDA approves Vosevi for Hepatitis C
The U.S. Food and Drug Administration has approved Vosevi to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis. Vosevi is a fixed-dose, combination tablet containing two previously approved drugs - sofosbuvir and velpatasvir - and a new drug, voxilaprevir. (Source: World Pharma News)
Source: World Pharma News - July 19, 2017 Category: Pharmaceuticals Tags: Featured FDA Regulatory Affairs Source Type: news

FDA Approves Vosevi (sofosbuvir, velpatasvir and voxilaprevir) for Hepatitis C
July 18, 2017 -- The U.S. Food and Drug Administration today approved Vosevi to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis. Vosevi is a fixed-dose, combination tablet... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - July 18, 2017 Category: Drugs & Pharmacology Source Type: news

FDA approves Vosevi for Hepatitis C
The U.S. Food and Drug Administration today approved Vosevi to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis. (Source: Food and Drug Administration)
Source: Food and Drug Administration - July 18, 2017 Category: American Health Source Type: news

Liver damage and alcohol: How do you know if you have symptomless cirrhosis?
CIRRHOSIS - is long-term liver damage that can eventually lead to liver failure and even increase the risk of cancer. (Source: Daily Express - Health)
Source: Daily Express - Health - July 12, 2017 Category: Consumer Health News Source Type: news

The Link Between Cirrhosis and Stroke: New Findings The Link Between Cirrhosis and Stroke: New Findings
Stroke incidence in patients with cirrhosis was double that of those without cirrhosis. Several factors probably explain why.Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 12, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery Viewpoint Source Type: news

DAAs for Chronic HCV in a Population Aged 65 Years and Older DAAs for Chronic HCV in a Population Aged 65 Years and Older
Are direct-acting antivirals safe and effective in elderly patients with HCV-related advanced fibrosis or cirrhosis?Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 12, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Hepatitis B jab to be added to immunisations of babies born in UK
Babies born from the 1 August will be offered new “hexavalent” jab in effort to clamp down on infections that cause cirrhosis and liver cancerAll babies born in the UK will receive the hepatitis B jab as part of their routine immunisations from the autumn in an effort to drive down viral infections that cause cirrhosis and liver cancer.The hepatitis B vaccine is to be added to the 5-in-1 jab that is already given to babies across the UK to protect them from diphtheria, tetanus, whooping cough, polio and bacterial infections known as Hib, or haemophilus influenzae type b, health officials said.Continue reading.....
Source: Guardian Unlimited Science - July 9, 2017 Category: Science Authors: Ian Sample Science editor Tags: Hepatitis B Science Society Children UK news Source Type: news

Statins May Curb Progression of Chronic Liver Disease Statins May Curb Progression of Chronic Liver Disease
Statins may slow the progression of hepatic fibrosis, prevent cirrhosis-related hepatic decompensation and reduce all-cause mortality in patients with chronic liver disease - but the evidence is low, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 26, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Relatives of people with fatty liver cirrhosis also at risk
(Reuters Health) - If a parent or sibling has cirrhosis due to non-alcoholic fatty liver disease, a person's odds of having liver scarring are more than 12 times higher than for people without close relatives who have this condition, a small study finds. (Source: Reuters: Health)
Source: Reuters: Health - June 22, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Case Report: Hyperammonemia to Be Considered in Cirrhosis Setting
Authors describe case of 58 - year - old man who received blood obtained 17, 20 days earlier (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 14, 2017 Category: Cancer & Oncology Tags: Family Medicine, Geriatrics, Gastroenterology, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Oncology, Pathology, Journal, Source Type: news

Antiviral therapy is effective in fighting hepatitis C | Letters
The Cochrane analysis casting doubt on this life-saving therapy is flawed and may deter patients from seeking it, say clinicians and scientistsWe are clinicians and scientists who have studied and treated patients with chronic hepatitis C virus infection over many years and patient groups that represent those affected by hepatitis C. We write in response to your article on the effectiveness of antiviral therapy (Hepatitis ‘wonder drug’ may be clinically ineffective, say experts, 9 June). The Cochrane review that you highlight analysed clinical trials, which are by nature short term, where the sole purpose was t...
Source: Guardian Unlimited Science - June 13, 2017 Category: Science Authors: Letters Tags: Hepatitis C Health Pharmaceuticals industry Medical research Drugs Business Science UK news Society Source Type: news

Cirrhosis Tied to Increased Stroke Risk (CME/CE)
(MedPage Today) -- Strongest association seen with subarachnoid and intracerebral hemorrhage (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 6, 2017 Category: Gastroenterology Source Type: news

Liver disease: Deadly form of the condition can also increase risk of stroke
LIVER damage can cause cirrhosis where the liver stops functioning properly. (Source: Daily Express - Health)
Source: Daily Express - Health - June 6, 2017 Category: Consumer Health News Source Type: news

Take a coffee or tea break to protect your liver
Chronic liver diseases rank as the 12th cause of death worldwide and many of these disorders are associated with unhealthy lifestyles. Conversely, a healthier lifestyle can help prevent or reverse liver disease. Liver-related mortality is closely related to the development of cirrhosis, the final consequence of progressive fibrosis, i.e. scarring of the liver resulting from chronic inflammation. According to a new study published in the Journal of Hepatology, researchers found that drinking coffee and herbal tea may protect against liver fibrosis, estimated as the degree of liver stiffness, which is high in extensive scarr...
Source: World Pharma News - June 6, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Cirrhosis Could Raise Stroke Risk
Title: Cirrhosis Could Raise Stroke RiskCategory: Health NewsCreated: 6/5/2017 12:00:00 AMLast Editorial Review: 6/6/2017 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - June 6, 2017 Category: Cardiology Source Type: news

Cirrhosis Tied to Stroke Risk (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Cirrhosis is associated with increased risk for stroke in older adults, according to a JAMA … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 5, 2017 Category: Primary Care Source Type: news

Study: Cirrhosis may increase risk for stroke
Cirrhosis -- a stiffening of liver tissue often tied to excessive drinking of alcohol -- may also raise an older person's odds for a stroke, a new study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 5, 2017 Category: Consumer Health News Source Type: news

Cirrhosis Could Raise Stroke Risk
Average yearly rate of the attacks doubled in people with the liver disease, study found Source: HealthDay Related MedlinePlus Pages: Cirrhosis, Stroke (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - June 5, 2017 Category: Consumer Health News Source Type: news

Cirrhosis Could Raise Stroke Risk
MONDAY, June 5, 2017 -- Cirrhosis -- a stiffening of liver tissue that's often tied to excessive drinking of alcohol -- may also raise an older person's odds for a stroke, a new study suggests. " In a nationally representative sample of elderly... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 5, 2017 Category: General Medicine Source Type: news