Many Cirrhosis Patients Harbor Multidrug-Resistant Bugs (CME/CE)
(MedPage Today) -- 18% of North Americans with infections; three-quarters of those in India (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - April 12, 2018 Category: American Health Source Type: news

Non-profit ’s $300 hepatitis C cure as effective as $84,000 alternative
Exclusive: 71 million people stand to benefit from reduced price treatment for virus which can lead to liver cirrhosis, cancer and deathAn affordable hepatitis C treatment has been shown to be safe and effective, with very high cure rates for patients including hard-to-treat cases, in interim clinical trial results that offer hope to the 71 million people living with the disease worldwide. The treatment is expected to cost $300 for 12 weeks, or $3.50 per day, in Malaysia, where trials were conducted along with Thailand – a fraction of the cost of other hepatitis C medicines produced by major drugmakers, which often r...
Source: Guardian Unlimited Science - April 12, 2018 Category: Science Authors: Julia Kollewe Tags: Medical research Hepatitis C Global health Global development Science Society Egypt Pharmaceuticals industry Source Type: news

Sensitive new assay detects hepatitis B infection in single liver cells and serum
(Elsevier) Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples. This assay can be used to diagnose HCC at an earlier stage to manage treatment more effectively. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 12, 2018 Category: International Medicine & Public Health Source Type: news

A third of bacterial infections in patients with cirrhosis across the world are multi-drug resistant
(European Association for the Study of the Liver) An international study reports a high prevalence of multi-drug-resistant bacteria in hospitalized patients with cirrhosis and significant regional differences in risk. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 12, 2018 Category: Biology Source Type: news

Mediterranean-style diet improves gut microbial diversity and reduces hospitalization
(European Association for the Study of the Liver) ILC 2018: Diets rich in vegetables, fermented milk products, tea, coffee and chocolate may improve outcomes in patients with liver cirrhosis. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 12, 2018 Category: Biology Source Type: news

Screening for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis achieving sustained virological response is likely to be cost effective
(European Association for the Study of the Liver) A Canadian study suggests that biannual or annual ultrasound screening for HCC is likely to be cost effective after a sustained virological response in those with hepatitis C-related cirrhosis, but not in those with advanced fibrosis without cirrhosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 12, 2018 Category: Cancer & Oncology Source Type: news

Scotland: Direct-acting antiviral agent therapy reduces the burden of HCV-related decompensated cirrhosis
(European Association for the Study of the Liver) National surveillance data and cost-effectiveness modeling provide complementary evidence to support the scale-up of DAA therapy in Scotland. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 12, 2018 Category: Infectious Diseases Source Type: news

Punjab, India: Mass treatment of a population with chronic hepatitis C infection produces high rates of cure
(European Association for the Study of the Liver) A program of decentralized public healthcare achieves high rates of cure regardless of genotype or the presence of cirrhosis: the Punjab Model. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 12, 2018 Category: Infectious Diseases Source Type: news

Exercise to Prevent Cirrhosis in Overweight and Obese Adults Exercise to Prevent Cirrhosis in Overweight and Obese Adults
Learn more about the preventive role of exercise against the development of cirrhosis among overweight or obese adults.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 5, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Cirrhosis of the liver symptoms: Four signs of long-term damage to the vital organ
CIRRHOSIS of the liver symptoms can be confused for those of less serious health conditions. The condition is scarring caused by long-term liver damage, and scar tissue then prevents the liver working properly. So what are the signs to look out for and is there a way of presenting it happening? (Source: Daily Express - Health)
Source: Daily Express - Health - April 4, 2018 Category: Consumer Health News Source Type: news

IFN-free Chronic HCV Therapy With DAAs and Risk for HCC IFN-free Chronic HCV Therapy With DAAs and Risk for HCC
Does IFN-free therapy with direct-acting antivirals alter the short-term risk for hepatocellular carcinoma in patients with cirrhosis?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 3, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Periodontitis in Patients With Cirrhosis Periodontitis in Patients With Cirrhosis
This study examined the prevalence and predictors of periodontitis in patients with cirrhosis. How is periodontitis related to nutritional and systemic inflammation status in these patients?BMC Oral Health (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 30, 2018 Category: Consumer Health News Tags: Dental & Oral Health Journal Article Source Type: news

Gut microbes could help better predict risk of hospitalization for patients with cirrhosis
(Virginia Commonwealth University) The gut microbiome -- a collection of bacteria and other microbes in the gut -- could be a highly accurate predictor of hospitalizations for patients with cirrhosis, according to a recently published study led by a researcher at Virginia Commonwealth University. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 30, 2018 Category: International Medicine & Public Health Source Type: news

Obesity, T2DM: Risk Factors Underlying Undiagnosed Cirrhosis Obesity, T2DM: Risk Factors Underlying Undiagnosed Cirrhosis
This study used transient elastography to screen for cirrhosis in a primary care setting.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 29, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Sofosbuvir/Velpatasvir in HCV With Cirrhosis or Fibrosis Sofosbuvir/Velpatasvir in HCV With Cirrhosis or Fibrosis
Is the combination of sofosbuvir and velpastavir a safe and effective therapeutic option for patients with HCV and advanced fibrosis or cirrhosis?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 29, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Twin saved by liver transplant, but it was too late for his brother
Devin and Nick Coats, 18, of Slidell, Louisiana, were diagnosed with stage 4 cirrhosis of the liver in March 2017. However, only one of them received a transplant while the other twin died. (Source: the Mail online | Health)
Source: the Mail online | Health - March 21, 2018 Category: Consumer Health News Source Type: news

Teenage twins needed liver transplants. One of them lived long enough to get his.
Eighteen-year-old Devin Coats was fighting for a second chance to live. His brother, Nicholas, was waiting to die. The identical twin brothers had both been diagnosed last year with Stage 4 cirrhosis of the liver — severe scarring commonly associated with alcoholism. In this case, it was the result of a gene mutation, and both […]Related:Former FDA commissioners say right-to-try bills could endanger ‘vulnerable patients’Top candidate to lead CDC is an HIV/AIDS researcher5 interesting findings about U.S. abortions from a new report on the current science (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - March 21, 2018 Category: Consumer Health News Source Type: news

WATCH: Twins suffering from liver disease, transplant saves one but other dies
Devin and Nick Coats were both diagnosed with stage 4 cirrhosis of the liver. (Source: ABC News: Health)
Source: ABC News: Health - March 21, 2018 Category: Consumer Health News Tags: Health Source Type: news

Oral Oxycodone/Naloxone for Pain Control in Cirrhosis Oral Oxycodone/Naloxone for Pain Control in Cirrhosis
Management of moderate-to-severe pain in patients with cirrhosis and HCC is challenging due to the high risk of serious adverse effects. Can an oral combination of oxycodone/naloxone be used safely?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 8, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

OBV/PTV/r + Sofosbuvir With or Without RBV for HCV Gt2 or 3 OBV/PTV/r + Sofosbuvir With or Without RBV for HCV Gt2 or 3
This study investigated the efficacy and safety of 12-week OBV/PTV/r + SOF with or without RBV in patients with HCV genotype 2 or 3 infection, including those with cirrhosis.Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 6, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Increased morbidity and mortality associated with falls among patients with cirrhosis - Ezaz G, Murphy SL, Mellinger J, Tapper EB.
BACKGROUND: Injuries are more morbid and complicated to manage in patients with cirrhosis. However, data are limited regarding the relative risk of injury and severity of injury from falls in patients with cirrhosis compared to those without cirrhosis. ... (Source: SafetyLit)
Source: SafetyLit - February 19, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Adding blood test to US improves liver cancer diagnosis
Performing a blood test in addition to an ultrasound exam improved the sensitivity...Read more on AuntMinnie.comRelated Reading: Lancet: Cancer survival rates improve but vary widely US elastography for liver evaluation: Worth the cost? JAMA: Cancer deaths fall 20% in U.S. since 1980 Cancer mortality continues to drop in U.S. HCC screening boosts survival rate in cirrhosis patients (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 12, 2018 Category: Radiology Source Type: news

HBV Reactivation in Patients With HCV/HBV Cirrhosis on DAAs HBV Reactivation in Patients With HCV/HBV Cirrhosis on DAAs
Does clearance or suppression of HCV by direct-acting antivirals in patients with chronic HCV hepatitis and HBV coinfection increase the risk of HBV reactivation?Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 29, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Cirrhosis Overview Video Cirrhosis Overview Video
This video discusses the pathophysiology of a cirrhotic liver as well as major complications and clinical signs and symptoms of cirrhosis.Osmosis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 26, 2018 Category: Consumer Health News Tags: Med Students Commentary Source Type: news

Medical News Today: What to eat if you have hepatitis C
Hepatitis C can damage the liver and lead to cirrhosis, or scarring of the liver. Damage to the liver may mean that a person needs to modify their diet. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 25, 2018 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Teen Drinking Ups Risk for Liver Diseases Later
MONDAY, Jan. 22, 2018 -- Men who started drinking in their teens are at increased risk for liver disease, Swedish researchers report. " Our study showed that how much you drink in your late teens can predict the risk of developing cirrhosis later in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 22, 2018 Category: General Medicine Source Type: news

Alcohol consumption in late teens can lead to liver problems in adulthood
(Elsevier) Alcohol is the leading cause of liver cirrhosis and liver-related deaths. Results of a large long-term study in Sweden have confirmed that drinking during late adolescence could be the first step towards liver problems in adulthood and that guidelines for safe alcohol intake in men might have to be revised downwards, reports the Journal of Hepatology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 21, 2018 Category: International Medicine & Public Health Source Type: news

Impact of HBV/HCV Coinfection on Cirrhosis Impact of HBV/HCV Coinfection on Cirrhosis
How does HBV and HCV coinfection impact liver fibrosis as compared with monoinfected patients? How should treatment be approached in this group?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 19, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Medical News Today: What is palmar erythema?
Palmar erythema is a rare condition that makes the palms of the hands turn red. Learn about the causes, including pregnancy and liver cirrhosis. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 12, 2018 Category: Consumer Health News Tags: Dermatology Source Type: news

Cirrhosis Is a Risk Factor for Atrial Fibrillation Cirrhosis Is a Risk Factor for Atrial Fibrillation
Is cirrhosis an independent risk factor for development of atrial fibrillation?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 10, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

An App to Prevent Hepatic Encephalopathy-related Readmissions An App to Prevent Hepatic Encephalopathy-related Readmissions
Can an easy-to-use mobile app which focuses on hepatic encephalopathy, ascites, and fall prevention help reduce readmissions in patients with cirrhosis?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 29, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Scientists discover a mutation could cause bad breath
Scientists from the University of California, Davis, believe it is important to identify the cause of persistent bad breath as it could be gum disease or, in more serious cases, liver cirrhosis. (Source: the Mail online | Health)
Source: the Mail online | Health - December 20, 2017 Category: Consumer Health News Source Type: news

What is DIOS?
Discussion Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane receptor (CFTR). It is found in the epithelium of the bronchi, intestine, pancreatic duct and biliary tree. It regulates chloride, bicarbonate and water secretion. The heterozygous state helps prevent against secretory diarrhea, but the homozygous state causes thickened secretions in the hollow tubes of the lungs and digestive tract. There are multiple mutations (> 2000) which have been currently classified into classes depending on their protein production and activity. CF patients generally are l...
Source: PediatricEducation.org - December 18, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Simeprevir + Daclatasvir in HCV GT1b With Advanced Disease Simeprevir + Daclatasvir in HCV GT1b With Advanced Disease
This study investigated the efficacy and safety of simeprevir plus daclatasvirin in a population of treatment-naive patients with chronic GT1b HCV infection with advanced fibrosis or cirrhosis.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 15, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Primary Biliary Cirrhosis
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - December 12, 2017 Category: General Medicine Source Type: news

YouTube star Angry Grandpa dies aged 67 of cirrhosis
Charles Marvin Green Jr., also known as Angry Grandpa, of Summerville, South Carolina, died on Sunday five months after being diagnosed with cirrhosis, his son Michael announced. (Source: the Mail online | Health)
Source: the Mail online | Health - December 11, 2017 Category: Consumer Health News Source Type: news

A South American amphibian could potentially hold the key in curing cirrhosis
(University of Surrey) The unique liver function of a South American amphibian, Siphonops annulatus, could pave the way to finding a cure to the devastating liver condition cirrhosis, a new study published in the prestigious Journal of Anatomy reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 6, 2017 Category: International Medicine & Public Health Source Type: news

Galectin slumps after NASH drug misses main goal of mid-stage trial
(Reuters) - Galectin Therapeutics Inc said its drug for the complex progressive fatty liver disease NASH led to some clinically meaningful results in patients with cirrhosis, but failed to achieve the main goal of a mid-stage trial, sending its shares plunging 48 percent on Tuesday. (Source: Reuters: Health)
Source: Reuters: Health - December 5, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Galectin says NASH drug misses main goal of midstage trial
(Reuters) - Galectin Therapeutics Inc said on Tuesday its experimental drug for the complex progressive fatty liver disease NASH led to some clinically meaningful results in patients with cirrhosis, but failed to achieve the main goal of a midstage trial. (Source: Reuters: Health)
Source: Reuters: Health - December 5, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

FDA Approves MRI Software for Fatty Liver Disease Screening FDA Approves MRI Software for Fatty Liver Disease Screening
The diagnosis of nonalcoholic fatty liver disease, which can rapidly progress to cirrhosis or liver cancer, could become easier with new multiparametric MRI software.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 4, 2017 Category: Consumer Health News Tags: Radiology News Source Type: news

Bad breath warning: These FIVE hidden health problems could be REVEALED by foul smell
BAD BREATH is unpleasant, but it could also be a sign of an underlying health condition, such as kidney disease or cirrhosis, says an expert. (Source: Daily Express - Health)
Source: Daily Express - Health - November 22, 2017 Category: Consumer Health News Source Type: news

Developing a New Score: How Machine Learning Improves Risk Prediction
Composite risk scores have been used for decades to identify disease risk and health status in the general population. However, current approaches often fail to identify people who would benefit from intervention or recommend unnecessary intervention. Machine learning promises to improve accuracy, ensuring targeted treatment for patients that need it and reducing unnecessary intervention. Framingham Risk Score, the gold standard for predicting the likelihood of heart disease, predicts hospitalizations with about 56% accuracy. It uses factors such as age, gender, smoking, cholesterol levels, and systolic blood pre...
Source: MDDI - November 17, 2017 Category: Medical Devices Authors: Heather R. Johnson Tags: R & D Source Type: news

Report suggests association between coffee and up to 70 percent reduced risk of liver disease
(Kaizo) A new roundtable report from the Institute for Scientific Information on Coffee (ISIC) in association with the British Liver Trust, on 'Looking after the liver: coffee, caffeine and lifestyle factors' highlights the potential role of coffee consumption in reducing the risk of liver diseases such as liver cancer and cirrhosis, with some studies reporting risk reduction of up to 70% (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 16, 2017 Category: Cancer & Oncology Source Type: news

US elastography for liver evaluation: Worth the cost?
Ultrasound elastography is a relatively new technology that can noninvasively...Read more on AuntMinnie.comRelated Reading: Elastography, color Doppler US avoid breast biopsies Elastography can help evaluate carotid plaque Shear-wave elastography spots Achilles tendinopathy Spleen stiffness correlates with cirrhosis complication Elastography aids assessment of focal prostate lesions (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 13, 2017 Category: Radiology Source Type: news

Statins, Decompensation, and Death in Alcoholic Cirrhosis Statins, Decompensation, and Death in Alcoholic Cirrhosis
Does regular use of statins improve outcomes and reduce mortality in patients with alcoholic cirrhosis?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 9, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

New study identifies targets to lessen the effects of alcoholic liver disease
(Elsevier) Chronic alcohol consumption causes abnormal fat accumulation in liver cells (steatosis) and liver fibrosis, which can lead to hepatitis, cirrhosis, and sometimes liver cancer. A new study in The American Journal of Pathology offers insights into the cellular aging that may trigger excessive fibrosis formation in the liver as well as possible means to inhibit these changes, which may lead to new therapeutic approaches for patients with ALD. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 8, 2017 Category: Biology Source Type: news

Living with NASH: An Unexpected Diagnosis
As our waistlines thicken and our activity levels decrease, another chronic illness threatens to disturb our comfortable lifestyles. And, because it ’s relatively unknown, diagnosis comes as a shock to patients, who usually associate liver disease with heavy consumption of alcohol.Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD), where fat accumulates in the liver. It is most commonly associated with obesity, insulin resistance, metabolic syndrome and/or genetic polymorphisms, and is aggravated by inflammation and fibrosis.  First identified in the 1980s, its ...
Source: EyeForPharma - November 3, 2017 Category: Pharmaceuticals Authors: Mariel Metcalfe Source Type: news

Mortality Rates for Overdose Patients Who Refuse Transport
This study was published March 28, 2016. The data obtained was from 2011-2013. Oh, how quickly things change in the drug trade. The Centers for Disease Control (CDC) reported the number of opioid-related deaths in 2014 was a 9% increase from the previous year.1 The illegal drug trade changes every day. More potent forms of opioids are being manufactured, and with that, more deaths occur. (Source: JEMS Patient Care)
Source: JEMS Patient Care - November 2, 2017 Category: Emergency Medicine Authors: Keith Wesley, MD, FACEP, FAEMS Tags: Patient Care Columns Source Type: news