HCC in Chronic HCV Patients Who Achieved SVR HCC in Chronic HCV Patients Who Achieved SVR
Does achieving SVR with DAAs reduce the incidence of hepatocellular carcinoma in chronic hepatitis C patients, genotype IV with liver cirrhosis and advanced hepatic fibrosis?Journal of Viral Hepatitis (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - July 17, 2020 Category: Infectious Diseases Tags: Gastroenterology Journal Article Source Type: news
Women Suffer Less NAFLD but More Advanced Fibrosis Women Suffer Less NAFLD but More Advanced Fibrosis
Given the higher risk of advanced fibrosis among women compared to men with NAFLD, it is plausible that cirrhosis and its complications may occur with greater frequency among women than in men.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 16, 2020 Category: Gastroenterology Tags: Ob/Gyn & Women ' s Health News Source Type: news
Fat cell hormone boosts potential of stem cell therapy
(Osaka University) Mesenchymal stem cell (MSC) therapy has shown promising results in the treatment of conditions ranging from liver cirrhosis to retinal damage, but results can be variable. Using a mouse heart failure model, researchers led by Osaka University found that levels of a fat cell-derived hormone called adiponectin in the host significantly affect the efficacy of MSC therapy. Administration of a drug that increases adiponectin in combination with MSCs is therefore likely to significantly improve the clinical outcome. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 10, 2020 Category: Biology Source Type: news
Blood tests can predict the risk of liver cirrhosis
(Karolinska Institutet) Repeated measurements of the biomarker FIB-4 in the blood every few years can predict the risk of developing severe liver disease, according to a new study from Karolinska Institutet in Sweden published in the Journal of Hepatology. The risk of liver cirrhosis increases if the levels of this biomarker rise between two testing occasions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 2, 2020 Category: International Medicine & Public Health Source Type: news
Giant leap in diagnosing liver disease
(Salk Institute) A collaborative team of Salk Institute and UC San Diego scientists have created a novel microbiome-based diagnostic tool that, with the accuracy of the best physicians, quickly and inexpensively identifies liver fibrosis and cirrhosis over 90 percent of the time in human patients. The non-invasive method relies on an algorithm to analyze patient stool samples--which contains traces of what lives in the gut--and could lead to improved patient care and treatment outcomes for liver disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 1, 2020 Category: Cancer & Oncology Source Type: news
Universal gut microbiome-derived signature predicts cirrhosis
(University of California - San Diego) UC San Diego School of Medicine researchers report that stool microbiomes of NAFLD patients are distinct enough to potentially be used to accurately predict which persons with NAFLD are at greatest risk for having cirrhosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 30, 2020 Category: International Medicine & Public Health Source Type: news
Transducer shell improves elastography measurements
A 3D-printed device with built-in pressure sensors that fits around an ultrasound...Read more on AuntMinnie.comRelated Reading:
Tongue ultrasound may identify obstructive sleep apnea
SWE effectively predicts cirrhosis complications
Elastography shows high reproducibility in breast lesions
Elastography helps liver transplant patients avoid biopsy
Shear-wave elastography tracks effects of knee surgery (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 23, 2020 Category: Radiology Source Type: news
NAFLD Progression Rates to Cirrhosis, Decompensation, Mortality NAFLD Progression Rates to Cirrhosis, Decompensation, Mortality
This study aimed to elucidate the natural history of NAFLD/NASH by evaluating the impact of liver disease severity and comorbid health conditions on risk of mortality and risk of disease progression.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 22, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Strength training benefits patients with cirrhosis
(Aarhus University) Three hours of weekly strength training combined with protein supplements leads to both bigger and stronger muscles in patients with cirrhosis. This is shown by a new study from Aarhus University and Aarhus University Hospital. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 11, 2020 Category: Biology Source Type: news
What Causes Free Peritoneal Fluid?
Discussion
Peritoneal fluid is normal. It decreases the friction of the peritoneum covering abdominal and pelvic organs and helps to protect them and allow their movement. A normal amount of peritoneal fluid is expected on radiological evaluation. Increased peritoneal fluid is a continuum and is concerning as a wide variety of pathological causes are associated with it such as abdominal trauma and appendicitis. At the far end of the scale is ascites that is the accumulation of free fluid more than 25 ml. It is usually associated with abdominal distension but fluid must accumulate before distension can occur and therefore i...
Source: PediatricEducation.org - June 8, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Women are not more likely to die of cirrhosis than men, despite fewer liver transplants
(Northwestern University) Prior studies suggested women might have higher mortality of cirrhosis of the liver than men. Women are also less likely to receive liver transplantation. But the research was unclear. A comprehensive new Northwestern Medicine study shows women are not more likely to die of liver cirrhosis than men, demonstrating that this liver disease affects men and women similarly. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 4, 2020 Category: International Medicine & Public Health Source Type: news
FDA approves Roche ’s Tecentriq in combination with Avastin for people with the most common form of liver cancer
Basel, 2 June 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the US Food and Drug Administration (FDA) has approved Tecentriq® (atezolizumab) in combination with Avastin® (bevacizumab) for the treatment of people with unresectable or metastatic hepatocellular carcinoma (HCC) who have not received p rior systemic therapy.“We’re excited that today’s approval of Tecentriq in combination with Avastin for unresectable or metastatic hepatocellular carcinoma brings a cancer immunotherapy option to people with this aggressive form of liver cancer,” said Levi Garraway, M.D., Ph.D., Chief Medical Officer ...
Source: Roche Media News - June 2, 2020 Category: Pharmaceuticals Source Type: news
Factors Impacting Fecal Microbiome in Liver Cirrhosis Factors Impacting Fecal Microbiome in Liver Cirrhosis
This study examined the contribution of medications, diet, and disease severity.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 13, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Liver transplant is associated with sustained improvement in tandem gait and risk of falls - Acharya C, White MB, Fagan A, Sterling RK, Stravitz RT, Puri P, Fuchs M, Luketic V, Sanyal AJ, Wade JB, Gilles H, Heuman DM, Tinsley F, Matherly S, Lee H, Siddiqui MS, Thacker LR, Bajaj JS.
BACKGROUND: Cirrhosis is associated with poor health-related quality of life (HRQOL), cognitive dysfunction (CD), and lack of coordination leading to falls. Tandem gait (TG; heel-toe) can be used to assess coordination. The impact and relationship between ... (Source: SafetyLit)
Source: SafetyLit - May 2, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Sugar, Fat, Alcohol … What’s Worse for the Liver?
This webinar will investigate the increasing mortality rates of liver disease in the UK associated with obesity and the excess consumption of alcohol. It will give an overview of non-alcoholic fatty liver disease (NAFLD), which is now the most common of liver disease affecting an estimated 25-30% of adults and 10% of children in the UK and worldwide. Both NAFLD and alcohol-related fatty liver can progress to severe liver disease including fibrosis, cirrhosis and hepatocellular carcinoma. The roles of genetics, obesity and dietary patterns i n the development and progression of liver disease will be discussed. In the c...
Source: The Nutrition Society - April 9, 2020 Category: Nutrition Authors: Jade Mitchell Source Type: news
