Cirrhosis Patients Skimp on Cancer Screening Because of Cost Cirrhosis Patients Skimp on Cancer Screening Because of Cost
Patients at high risk for liver cancer report that expense is often an obstacle to preventive screening and care, putting their lives at risk, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 13, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Patients With Cirrhosis Have Considerable Financial Burden
FRIDAY, Nov. 8, 2019 -- The considerable financial burden of cirrhosis medical care is associated with lower surveillance for hepatocellular carcinoma (HCC), according to a study presented at The Liver Meeting, the annual meeting of the American... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 8, 2019 Category: Pharmaceuticals Source Type: news

Characteristics, Trends of HCC in Patients Without Cirrhosis Characteristics, Trends of HCC in Patients Without Cirrhosis
This study aimed to describe the frequency and characteristics of non-cirrhotic hepatocellular carcinoma. What contribution does NAFLD make to the burden of non-cirrhotic HCC?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 30, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Mayo scientists reverse fibrosis in preclinical studies
ROCHESTER, Minn. -- In cell and mouse models, Mayo Clinic researchers and collaborators have identified a way to slow and reverse the process of uncontrolled internal scarring, called fibrosis. This disease process has few effective therapies, no cure and can be fatal when it occurs in organs such as the liver (cirrhosis) or lungs (pulmonary [...] (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - October 29, 2019 Category: Hospital Management Source Type: news

iRhom2 inhibits bile duct obstruction-induced liver fibrosis
Chronic liver disease can induce prolonged activation of hepatic stellate cells, which may result in liver fibrosis. Inactive rhomboid protein 2 (iRhom2) is required for the maturation of A disintegrin and metalloprotease 17 (ADAM17, also called TACE), which is responsible for the cleavage of membrane-bound tumor necrosis factor–α (TNF-α) and its receptors (TNFRs). Here, using the murine bile duct ligation (BDL) model, we showed that the abundance of iRhom2 and activation of ADAM17 increased during liver fibrosis. Consistent with this, concentrations of ADAM17 substrates were increased in plasma samples f...
Source: Signal Transduction Knowledge Environment - October 28, 2019 Category: Science Authors: Sundaram, B., Behnke, K., Belancic, A., Al-Salihi, M. A., Thabet, Y., Polz, R., Pellegrino, R., Zhuang, Y., Shinde, P. V., Xu, H. C., Vasilevska, J., Longerich, T., Herebian, D., Mayatepek, E., Bock, H. H., May, P., Kordes, C., Aghaeepour, N., Mak, T. W., Tags: STKE Research Articles Source Type: news

Nonalcoholic Steatohepatitis with Compensated Cirrhosis: Developing Drugs for Treatment Guidance for Industry
Guidance for Industry (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 25, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Antibiotic treatment for spontaneous bacterial peritonitis in people with decompensated liver cirrhosis: a network metaanalysis
This review (12 trials, n=1278; 13 antibiotics) found short ‐term mortality after spontaneous bacterial peritonitis (SBP) is approx. 25%. However, authors report significant uncertainty about which antibiotic therapy is better in people with SBP. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 25, 2019 Category: Consumer Health News Source Type: news

Safety of Non-selective b-Blockers in Decompensated Cirrhosis Safety of Non-selective b-Blockers in Decompensated Cirrhosis
Treatment with non-selective beta blockers in patients with decompensated cirrhosis and ascites remains controversial. What factors might contribute to adverse events?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 23, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Mavyret Approved as 8-Week Treatment for Hep C, Compensated Cirrhosis
Title: Mavyret Approved as 8-Week Treatment for Hep C, Compensated CirrhosisCategory: Health NewsCreated: 10/1/2019 12:00:00 AMLast Editorial Review: 10/1/2019 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - October 1, 2019 Category: Nutrition Source Type: news

Mavyret Approved as 8-Week Treatment for Hep C, Compensated Cirrhosis
MONDAY, Sept. 30, 2019 -- Approval of Mavyret (glecaprevir and pibrentasvir) tablets has been expanded to eight-week treatment for treatment-naive patients aged 12 years and older with chronic hepatitis C virus (HCV) genotypes 1 through 6 and... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 30, 2019 Category: General Medicine Source Type: news

FDA Approves Mavyret (glecaprevir/pibrentasvir) Treatment Duration of Eight Weeks for Treatment-Na ïve Patients with Chronic Hepatitis C and Compensated Cirrhosis Across All Genotypes
NORTH CHICAGO, Ill., Sept. 26, 2019 /PRNewswire/ -- AbbVie (NYSE: ABBV), a research-based global biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has granted approval of Mavyret (glecaprevir/pibrentasvir)... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 27, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Further Expands Approval of HCV Combo Drug Mavyret FDA Further Expands Approval of HCV Combo Drug Mavyret
Mavyret is the first 8-week treatment approved for all treatment-naive adult and certain pediatric patients with any hepatitis C virus genotype, both without cirrhosis and with compensated cirrhosis.FDA Approvals (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - September 27, 2019 Category: Transplant Surgery Tags: Gastroenterology News Alert Source Type: news

Sepsis in patients with cirrhosis awaiting liver transplantation: new trends and management
Bacterial infections are more frequent and severe in patients with advanced liver disease and, therefore, in liver transplant candidates. The increased risk of infection in these patients parallels the severity of the immune dysfunction associated with cirrhosis, featured by systemic inflammation and progressive immunodeficiency. Other factors contribute to this risk, such as genetic polymorphisms, proton-pump inhibitor overuse, the numerous invasive procedures and hospitalizations these patients go through, or the immunosuppressive effects of malnutrition or alcohol abuse. Bacterial infections have a great impact on disea...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Sepsis-related Organ Failure Assessment Score is a strong predictor of survival in acute-on-chronic liver failure
The objective of this study was to identify variables associated with mortality. The mortality was high in these severely ill patients, even when they received optimum supportive therapy in the ICU. The finding that the SOFA score and age best predicted mortality shows that the increased mortality was caused mainly by insufficiency of organs other than the liver. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 4, 2019 Category: Consumer Health News Source Type: news

HCC and DAA Treatment in Decompensated Cirrhosis HCC and DAA Treatment in Decompensated Cirrhosis
This review explores controversies surrounding the potential impact of DAA therapy on the incidence and prognosis of hepatocellular carcinoma in patients with advanced liver disease.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 28, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

The effect of cirrhosis on trauma outcomes: a systematic review and meta-analysis - Serrano E, Liu P, Nwabuo AI, Langness S, Juillard C.
BACKGROUND: The negative effect of cirrhosis on mortality following traumatic injury has been quantified in multiple observational studies. However, to our knowledge, the information contained in these studies has never been synthesized. The aims of this s... (Source: SafetyLit)
Source: SafetyLit - August 10, 2019 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

SWE identifies malignant breast microcalcifications
Ultrasound with a shear-wave elastography (SWE) technique can distinguish benign...Read more on AuntMinnie.comRelated Reading: SWE improves plantar fasciitis diagnosis Shear-wave elastography useful for assessing rectal tumor depth Shear-wave elastography helps diagnose Graves' disease SWE helps clinicians evaluate Achilles tendon health 2D shear-wave elastography diagnoses cirrhosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 29, 2019 Category: Radiology Source Type: news

HCC in Patients With NAFLD Without Cirrhosis HCC in Patients With NAFLD Without Cirrhosis
This study compared the clinical characteristics of patients with non-cirrhotic NAFLD-HCC to those with cirrhosis. Do outcomes differ between the two groups?Liver International (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - July 12, 2019 Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news

The Albumin Effect in Cirrhosis Becomes Clearer The Albumin Effect in Cirrhosis Becomes Clearer
Dr David Johnson on how a new study sheds light on the benefits of IV albumin and why it may soon be standard of care in this indication.Medscape Gastroenterology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 10, 2019 Category: Gastroenterology Tags: Gastroenterology Viewpoint Source Type: news

Outcomes in HBV-related Acute on Chronic Liver Failure Outcomes in HBV-related Acute on Chronic Liver Failure
This study compared the 5-year survival rate and incidence rate of hepatocellular carcinoma between patients with HBV-related acute on chronic liver failure and HBV cirrhosis.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 10, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

SWE improves plantar fasciitis diagnosis
Shear-wave elastography (SWE) boosts diagnostic accuracy in patients with plantar...Read more on AuntMinnie.comRelated Reading: Shear-wave elastography useful for assessing rectal tumor depth Shear-wave elastography helps diagnose Graves' disease SWE helps clinicians evaluate Achilles tendon health 2D shear-wave elastography diagnoses cirrhosis Ultrasound options abound for diagnosing liver disease (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 3, 2019 Category: Radiology Source Type: news

Ultrasound useful for evaluating liver steatosis
Ultrasound is a reliable alternative to MRI for assessing liver steatosis in...Read more on AuntMinnie.comRelated Reading: Ultrasound identifies alcohol-induced liver disease Steatosis complicates MR elastography for liver fibrosis US elastography for liver evaluation: Worth the cost? HCC screening boosts survival rate in cirrhosis patients Practice of Ultrasound: Part 13 -- Liver fat and fibrosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - May 31, 2019 Category: Radiology Source Type: news

Cirrhosis, cancer risks higher with fatty liver - especially in diabetics
(Reuters Health) - Fatty liver disease that's not related to alcohol use is linked with an increased risk of cirrhosis and liver cancer, especially in people with diabetes, according to a large study from Europe. (Source: Reuters: Health)
Source: Reuters: Health - May 27, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Adverse Liver Outcomes Up With Diagnosis of NAFLD/NASH
WEDNESDAY, May 22, 2019 -- The risks for cirrhosis and hepatocellular carcinoma (HCC) are increased for patients with a recorded diagnosis of nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH), according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 22, 2019 Category: Pharmaceuticals Source Type: news

Medical News Today: Cirrhosis and liver cancer risk higher in people with type 2 diabetes
A large European study now suggests that many diagnoses of cirrhosis and liver cancer come too late, and that diabetes might be an independent risk factor. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 21, 2019 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Walking and strength training may decrease the risk of dying from liver disease
(Digestive Disease Week) Physical activity, including walking and muscle-strengthening activities, were associated with significantly reduced risk of cirrhosis-related death, according to research presented at Digestive Disease Week ® (DDW) 2019. Chronic liver disease is increasing, partly due to the obesity epidemic, and currently there are no guidelines for the optimal type of exercise for the prevention of cirrhosis-related mortality. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 19, 2019 Category: International Medicine & Public Health Source Type: news

Diabetes patients at higher risk of deadly liver disease, finds study of 18 million people
(Queen Mary University of London) Many patients with potentially deadly liver cirrhosis and liver cancer are being diagnosed at late advanced stages of disease, according to a study led by Queen Mary University of London and the University of Glasgow. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 19, 2019 Category: International Medicine & Public Health Source Type: news

Shear-wave elastography useful for assessing rectal tumor depth
Shear-wave elastography (SWE) is a useful way to evaluate the depth of invasion...Read more on AuntMinnie.comRelated Reading: Shear-wave elastography helps diagnose Graves' disease SWE helps clinicians evaluate Achilles tendon health 2D shear-wave elastography diagnoses cirrhosis Ultrasound options abound for diagnosing liver disease Elastography works for diagnosing soft-tissue lesions (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - May 17, 2019 Category: Radiology Source Type: news

Effect of a multistrain probiotic on cognitive function and risk of falls in patients with cirrhosis: a randomized trial - Rom án E, Nieto JC, Gely C, Vidal S, Pozuelo M, Poca M, Juárez C, Guarner C, Manichanh C, Soriano G.
Probiotics can modulate gut microbiota, intestinal permeability, and immune response and could therefore improve cognitive dysfunction and help avoid potential consequences, such as falls, in patients with cirrhosis. The aim of this study was to evaluate t... (Source: SafetyLit)
Source: SafetyLit - May 10, 2019 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Shear-wave elastography helps diagnose Graves' disease
Shear-wave elastography (SWE) is an effective additional tool to complement...Read more on AuntMinnie.comRelated Reading: Elastography can help characterize breast tumors SWE helps clinicians evaluate Achilles tendon health 2D shear-wave elastography diagnoses cirrhosis Ultrasound options abound for diagnosing liver disease Elastography works for diagnosing soft-tissue lesions (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 24, 2019 Category: Radiology Source Type: news

New class of medicines shows promise
'Gene silencing' spares patients the crippling pain of intermittent porphyria Related items fromOnMedica Higher cancer risk from chronic diseases Hepatocellular carcinoma risk, cirrhosis and hepatitis C Kidney disease hits 850 million people Commonest genetic mutation causes much morbidity Prevention screening for one third of population (Source: OnMedica Latest News)
Source: OnMedica Latest News - April 14, 2019 Category: UK Health Source Type: news

The Big Number: 17.6 million Americans suffer from alcoholism
Beyond affecting everyday life functioning, alcohol abuse increases risk of cancer, liver cirrhosis, heart problems and stroke. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - April 6, 2019 Category: Consumer Health News Authors: Linda Searing Source Type: news

Fecal Microbiome Signature Detects Cirrhosis in Nonalcoholic Fatty-Liver Disease Fecal Microbiome Signature Detects Cirrhosis in Nonalcoholic Fatty-Liver Disease
A fecal microbiome signature accurately detects cirrhosis in patients with nonalcoholic fatty-liver disease (NAFLD), researchers report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 5, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Glecaprevir/Pibrentasvir in Chronic HCV Genotype 3 Infection Glecaprevir/Pibrentasvir in Chronic HCV Genotype 3 Infection
Is glecaprevir/pibrentasvir effective in patients with chronic HCV genotype 3 infection and compensated cirrhosis?Journal of Viral Hepatitis (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - April 3, 2019 Category: Intensive Care Tags: Gastroenterology Journal Article Source Type: news

Exosomes from Blood Carry RNA Signatures of Liver Cancer
A small study finds that the tiny extracellular vesicles from patients with hepatocellular carcinoma have RNA content distinct from patients with cirrhosis only. (Source: The Scientist)
Source: The Scientist - April 2, 2019 Category: Science Tags: News & Opinion Source Type: news

Researcher finds dangerous levels of metals in liquor sold in Uganda
UCLA Extension ’s Ochan Otim is a chemist who specializes in developing methods for quantifying and assessing the health risk associated with organic and metal contaminants in the environment. For the last few years, Otim, who grew up in Uganda, has been driven to use his expertise to try to help solve a dangero us mystery in his country of birth.Why were so many people having health problems and even dying because of alcohol consumption?The two-decade civil war in Uganda beginning in the late 1980s ravaged the country with violence, abductions, concentration camps and  starvation. The inhumane conditions and ab...
Source: UCLA Newsroom: Health Sciences - April 1, 2019 Category: Universities & Medical Training Source Type: news

What Does the Liver Do?
Discussion The liver is one of the largest organs in the body, weighing just over 3 pounds in an adult. It is found in the upper right abdomen, under the right dome of the diaphragm. Grossly, it has asymmetric lobes with the right being larger than the left. The lobes are separated by a fibrous connective tissue band that also anchors the liver in the abdominal cavity. The gallbladder is located on the inferior surface of the liver and stores bile, which is then released into the duodenum. Microscopically, the liver cells are arranged in lobules with canals carrying blood vessels and bile ducts. At any moment about 10-13% ...
Source: PediatricEducation.org - April 1, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Movement toward a poop test for liver cirrhosis
(University of California - San Diego) In a study of people with nonalcoholic fatty liver disease and their twins and other close relatives, UC San Diego researchers were able to diagnose liver cirrhosis simply by analyzing a person's stool microbes. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 29, 2019 Category: Biology Source Type: news

What is liver cirrhosis? (and is alcohol always the cause of it?)
(Natural News) Cirrhosis is a term for advanced liver scarring. For the most part, it’s usually associated with drinking too much over time — and for good reason. According to data from the Centers for Disease Control and Prevention, excessive drinking can lead to both short-term and long-term damage. Immediate effects include injuries (such as vehicle crashes or... (Source: NaturalNews.com)
Source: NaturalNews.com - March 26, 2019 Category: Consumer Health News Source Type: news

Mayo Clinic researchers identify potential new therapy for liver diseases
(Mayo Clinic) Drug therapy may effectively treat a potentially life-threatening condition associated with cirrhosis and other chronic liver diseases, according to a new study by Mayo Clinic researchers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 22, 2019 Category: International Medicine & Public Health Source Type: news

Mayo Clinic researchers identify potential new therapy for liver diseases
ROCHESTER, Minn. -- Drug therapy may effectively treat a potentially life-threatening condition associated with cirrhosis and other chronic liver diseases, according to a new study by Mayo Clinic researchers. The study was posted in March on Gastroenterology, the online journal of the American Gastroenterological Association. Print publication is scheduled for July. While therapies have been [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 21, 2019 Category: Research Source Type: news

MRI-guided cryoablation a boon for HCC patients
With a 1-tesla open scanner and some finesse, Chinese researchers are using...Read more on AuntMinnie.comRelated Reading: CBCT-guided radiotherapy shows promise for HCC 3D printing enables CT- and MR-guided ablation simulation Contrast US clears up indeterminate HCC cases on MRI US surveillance of HCC subject to image quality issues HCC screening boosts survival rate in cirrhosis patients (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 21, 2019 Category: Radiology Source Type: news

A Patient with Chronic Pancreatitis, Requesting Demerol
A 47 y/o woman with cirrhosis, HCV, and chronic pancreatitis requests Demerol for the worst abdominal pain she has ever had. What's your diagnosis?   (Source: ConsultantLive)
Source: ConsultantLive - March 10, 2019 Category: Internal Medicine Authors: Brady Pregerson, MD Tags: Gastrointestinal Disorders Source Type: news

A Gulp Of Genetically Modified Bacteria Might Someday Treat A Range Of Illnesses
Researchers think genetically engineered versions of microbes that can live in humans could help treat some rare genetic disorders and perhaps help with Type 1 diabetes, cirrhosis and cancer.(Image credit: Julia Ritchey/KUER) (Source: NPR Health and Science)
Source: NPR Health and Science - March 8, 2019 Category: Consumer Health News Authors: Rob Stein Source Type: news

Liver Transplant Listing for HCV-associated Cirrhosis and HCC Liver Transplant Listing for HCV-associated Cirrhosis and HCC
How has the availability of direct-acting antiviral therapy impacted liver transplantation indications and waiting list outcomes in patients with chronic hepatitis C?Journal of Viral Hepatitis (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - March 6, 2019 Category: Transplant Surgery Tags: Gastroenterology Journal Article Source Type: news

US equipment manufacturers show versatility, usability at ECR
Ultrasound users have had a clear message for the imaging industry: Make the...Read more on AuntMinnie.comRelated Reading: Ultrasound equal to DEXA for assessing bone health Transcranial sonography identifies Parkinson's earlier SWE helps clinicians evaluate Achilles tendon health Start-up BURL develops ultrasound-based 'ECG for stroke' 2D shear-wave elastography diagnoses cirrhosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 5, 2019 Category: Radiology Source Type: news

Weighing Bariatric Surgery Costs, Benefits, and Risks in NASH Cirrhosis Patients (CME/CE)
(MedPage Today) -- Could be cost-effective in NASH with compensated cirrhosis, modeling study suggests (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - March 5, 2019 Category: Endocrinology Source Type: news

Towards a blood test for early-stage liver disease
(EMBO) One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease -- non-alcoholic fatty liver disease (NAFLD) -- causes no symptoms initially but can develop into end-stage liver cirrhosis. A discovery, published today in Molecular Systems Biology, paves the way for a simple blood test to detect early stages of NAFLD, opening up the possibility of preventing the development of liver cirrhosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2019 Category: International Medicine & Public Health Source Type: news

Cannabis can reverse the effects of alcohol-induced liver damage
(Natural News) A January 2018 study published in Liver International concluded that cannabis may reduce the incidence of liver disease in alcoholics. The study found that using cannabis correctly significantly lowered the odds of various liver diseases such as hepatitis, cirrhosis, and even hepatocellular carcinoma, a type of liver cancer. These findings were based on... (Source: NaturalNews.com)
Source: NaturalNews.com - March 1, 2019 Category: Consumer Health News Source Type: news

Researchers identify potential mechanism to control nonalcoholic fatty liver disease
FINDINGSIn a comprehensive, nine-year-long study in mice, researchers profiled more than 300 liver and plasma lipid species and more than 5,000 liver proteins. The combined data helped researchers to identify new mechanisms that control the metabolism of lipids (molecules that include fat) and to discover a protein that regulates lipids. They found that silencing one particular protein, called PSMD9, is a potential therapeutic strategy to reduce nonalcoholic fatty liver disease.BACKGROUNDNonalcoholic fatty liver disease is the buildup of excess fat in liver cells not caused by alcohol. The disease affects about 25 percent ...
Source: UCLA Newsroom: Health Sciences - February 28, 2019 Category: Universities & Medical Training Source Type: news