Intestinal fungi worsen alcoholic liver disease
(University of California - San Diego) Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse. Yet apart from alcohol abstinence, there are no specific treatments to reduce the severity of alcohol-associated liver disease. Researchers at University of California San Diego School of Medicine and J. Craig Venter Institute (JCVI) have linked intestinal fungi to increased risk of death for patients with alcohol-related liver disease. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 22, 2017 Category: International Medicine & Public Health Source Type: news

Primary biliary cirrhosis
(Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - May 16, 2017 Category: Consumer Health News Source Type: news

New pill spares women trauma of liver transplant
In the UK, 20,000 people – 90 per cent of them women – suffer from primary biliary cholangitis, also known as primary biliary cirrhosis (PBC). (Source: the Mail online | Health)
Source: the Mail online | Health - May 13, 2017 Category: Consumer Health News Source Type: news

Gene Variant Predicts Liver Recovery After HCV Cure (CME/CE)
(MedPage Today) -- Finding might help treatment options in decompensated cirrhosis (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 8, 2017 Category: Gastroenterology Source Type: news

Gene Variation Predicts Recovery in Decompensated Hep C Gene Variation Predicts Recovery in Decompensated Hep C
Genetic differences that are associated with recovery in patients with hepatitis C and decompensated cirrhosis who achieve a sustained virologic response could someday guide liver transplantation.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 7, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Study: Genetic markers may predict which HCV, cirrhosis patients improve with treatment
This study was presented at Digestive Disease Week ® (DDW) 2017, the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 6, 2017 Category: Global & Universal Source Type: news

Stool microbes predict advanced liver disease
Nonalcoholic fatty liver disease (NAFLD) -- a condition that can lead to liver cirrhosis and cancer -- isn't typically detected until well advanced. Even then, diagnosis requires a biopsy. To more easily detect NAFLD, researchers report that the microbial makeup of a patient's stool -- gut microbiome -- can be used to predict advanced NAFLD with 88 to 94 percent accuracy. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 2, 2017 Category: Science Source Type: news

Managing Upper GI Bleeding Due to Portal Hypertension Managing Upper GI Bleeding Due to Portal Hypertension
Dr Rowan Zetterman examines new practice guidance for the diagnosis and management of patients with cirrhosis and portal hypertension.Medscape Gastroenterology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - April 27, 2017 Category: Gastroenterology Tags: Gastroenterology Expert Column Source Type: news

New System Detects Cirrhosis in Fatty Liver Disease New System Detects Cirrhosis in Fatty Liver Disease
With up to 40% of patients in primary care in the US and Europe affected by fatty liver disease, identifying who will develop fibrosis or cirrhosis is a challenge, but a new strategy appears to help.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 26, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Long-Term Albumin Tx Ups Survival in Liver Failure (CME/CE)
(MedPage Today) -- Patients with decompensated cirrhosis also report better quality of life (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 25, 2017 Category: Gastroenterology Source Type: news

Sofosbuvir Plus an NS5A Inhibitor for HCV GT3 and Cirrhosis Sofosbuvir Plus an NS5A Inhibitor for HCV GT3 and Cirrhosis
This study evaluated the efficacy of regimens of SOF plus an NS5A inhibitor with or without RBV in this group.Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 25, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Albumin Improves Survival in Decompensated Cirrhosis Albumin Improves Survival in Decompensated Cirrhosis
A new study answers an old question by showing that adjunctive albumin improves survival and reduces complications in patients with decompensated cirrhosis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 24, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Climate Tied to Alcohol-Related Liver Disease
(MedPage Today) -- Is alcoholic cirrhosis a product of cold, gray weather? (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 24, 2017 Category: Gastroenterology Source Type: news

How Common is α -1-Antitrypsin Deficiency?
Discussion α-1-Antitrypsin Deficiency (A1AT) is a common single-gene mutation disease that is homozygous recessive. The normal allele is called M and the most common abnormal allele is Z. There are other alleles though. The gene codes for one of the primary protease inhibitors in the serum, thus those who are homozygous for the Z gene are sometimes referred to as “PIZZ” or “PIZ.” α-1-Antitrypsin is found in all body tissues but is especially important in the serum and lung. As noted it is one of the primary neutrophil protease inhibitors in the serum, and acts to neutralize these enzymes...
Source: PediatricEducation.org - April 24, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Cold weather, fewer sun hours are associated with increased rates of alcoholic cirrhosis
Colder and less sunny regions of the world have higher rates of alcoholic cirrhosis, a disease caused by excessive drinking which results in irreversible scarring of the liver, new research shows. An international team of scientists found that every increase in temperature of one degree Celsius was linked with a decrease in the alcohol-attributable fraction of cirrhosis of 0.3 percent. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 23, 2017 Category: Science Source Type: news

HCV Treatment Can Avert Transplant Even in Severe Disease
(MedPage Today) -- A quarter of patients with decompensated cirrhosis could safely get off waiting list (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 22, 2017 Category: Gastroenterology Source Type: news

Long-term treatment of decompensated cirrhosis with human albumin improves survival
(European Association for the Study of the Liver) Results from the ANSWER study showed that long-term administration of human albumin improves the survival rate of patients with decompensated cirrhosis. The study, presented at The International Liver Congress ™ 2017 in Amsterdam, The Netherlands, demonstrated that treatment with human albumin also improved the management of ascites (accumulation of fluid in the abdominal cavity) and quality of life, and reduced the incidence of severe complications of the disease and the need for hospitalization. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 22, 2017 Category: Global & Universal Source Type: news

Cold weather & fewer sun hours are associated with increased rates of alcoholic cirrhosis
(European Association for the Study of the Liver) New data presented at The International Liver Congress ™ 2017 in Amsterdam, The Netherlands, suggests that colder and less sunny regions of the world have higher rates of alcoholic cirrhosis, a disease caused by excessive drinking which results in irreversible scarring of the liver. An international team of scientists found that every increase in temperature of one degree Celsius was linked with a decrease in the alcohol-attributable fraction of cirrhosis of 0.3 percent. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 22, 2017 Category: Global & Universal Source Type: news

Eight Weeks of Treatment with AbbVie's Investigational, Pan-Genotypic Regimen of Glecaprevir/Pibrentasvir (G/P) Achieved High SVR(12) Rates in Challenging to Treat Genotype 3 Chronic Hepatitis C
95 percent of patients infected with genotype 3 (GT3) chronic hepatitis C virus (HCV), without cirrhosis and who are new to treatment, achieved SVR(12) with 8 weeks of treatment(1) Together with previously reported data, these study results support the ... Biopharmaceuticals AbbVie, glecaprevir, pibrentasvir, hepatitis C, ENDURANCE-3 (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 21, 2017 Category: Pharmaceuticals Source Type: news

Antibiotic Cuts Death Risk in Severe Cirrhosis (CME/CE)
(MedPage Today) -- Analysis also shows reduced rate of infection (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 20, 2017 Category: Gastroenterology Source Type: news

New Hep C Combo Cures Most Patients with Cirrhosis (CME/CE)
(MedPage Today) -- Glecaprevir/pibrentasvir highly effective against most hepatitis C genotypes (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 20, 2017 Category: Gastroenterology Source Type: news

Gum Disease, Mortality Linked in Cirrhosis
(MedPage Today) -- Severity of periodontitis increases risk (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 20, 2017 Category: Gastroenterology Source Type: news

Investigational DAA treatment combination effective and improves patient-reported outcomes
(European Association for the Study of the Liver) Analysis of patient outcome data from the POLARIS-1, 2, 3 and 4 studies demonstrate that patients with HCV and cirrhosis have greatest improvements of PRO scores when taking treatment with sofosbuvir + velpatasvir, ± voxilaprevir, an anti-HCV regimen that has been shown to be safe and effective against all HCV genotypes. The analysis, presented at The International Liver Congress ™ 2017 in Amsterdam, The Netherlands, showed that achievement of SVR12 was associated with improvements in PROs. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 20, 2017 Category: Infectious Diseases Source Type: news

Long-term antibiotic prophylaxis reduces mortality in people with advanced liver disease
(European Association for the Study of the Liver) A multicenter, randomized, controlled study presented today found that long-term oral antibiotic therapy with norfloxacin improved the prognosis of people with life-threatening advanced liver disease. The study, presented at The International Liver Congress ™ 2017 in Amsterdam, The Netherlands, showed that norfloxacin administration for six months was associated with a reduced risk of death and infection at six months in patients with Child-Pugh class C cirrhosis, a very severe and advanced stage of liver disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 20, 2017 Category: Infectious Diseases Source Type: news

Severe gum disease strongly predicts higher mortality in cirrhosis
(European Association for the Study of the Liver) Results presented today from a prospective study in patients with irreversible scarring of the liver (cirrhosis) demonstrates that severe periodontitis (an inflammatory gum disease) strongly predicts higher mortality in this population, after adjustments for various risk factors. The study was presented at The International Liver Congress ™ 2017 in Amsterdam, The Netherlands. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 20, 2017 Category: Global & Universal Source Type: news

Worldwide lack of early referral of patients with alcoholic liver disease
(European Association for the Study of the Liver) Results from an analysis of over 3,000 patients highlights there is significant disparity in the referral of patients with liver disease, and that those with alcoholic liver disease (ALD) are 12 times more likely to present at an advanced rather than early stage. The study, presented at The International Liver Congress ™ 2017 in Amsterdam, showed that in those patients with two causes of cirrhosis, alcohol abuse also leads to a more advanced stage of presentation. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 20, 2017 Category: Global & Universal Source Type: news

This molecule stops pancreatic cancer cells from spreading
This micrograph shows pancreatic ductal adenocarcinoma (the most common type of pancreatic cancer). [Image by KGH – Own work, CC BY-SA 3.0]Wake Forest Baptist Medical Center scientists have identified molecules that could be the next therapeutic solution for pancreatic cancer. Pancreatic cancer is one of the most lethal forms of cancer. About 53,670 people are expected to be diagnosed with pancreatic cancer this year with 43,090 dying from it, according to the American Cancer Society. The lifetime risk of developing pancreatic cancer is about 1 in 65 but can be reduced by knowing the risk factors. The risk ...
Source: Mass Device - April 19, 2017 Category: Medical Equipment Authors: Danielle Kirsh Tags: Biotech Oncology Cancer pancreatic cancer Tianjin Medical University University of Texas Wake Forest Baptist Medical Center Source Type: news

Nutrient offers hope to stop deadly march toward cirrhosis, liver cancer
(Oregon State University) A new study suggests that one type of omega 3 fatty acid offers people who are obese or have a poor diet a chance to avoid serious liver damage. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 19, 2017 Category: Cancer & Oncology Source Type: news

Hep C Treatment Triumph Drives Broader Focus for ILC 2017 Hep C Treatment Triumph Drives Broader Focus for ILC 2017
Clinical trial results for biliary cirrhosis and hepatocellular carcinoma are highly anticipated at the upcoming International Liver Congress (ILC).Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 11, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Cirrhosis Paradox: Is the Risk for Clotting or for Bleeding? Cirrhosis Paradox: Is the Risk for Clotting or for Bleeding?
Previously thought to be'anticoagulated,'patients with cirrhosis really might be hypercoagulable. Dr David Johnson explains why this paradox is a'must understand'for all who manage this condition.Medscape Gastroenterology (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - April 10, 2017 Category: Surgery Tags: Gastroenterology Commentary Source Type: news

Overweight young men 'more likely to get severe liver disease'
Conclusion This cohort study aimed to assess whether a high BMI in late adolescence is associated with an increased risk of severe liver disease and liver cancer in later life. The researchers generally found a higher BMI was associated with an increased risk of severe liver disease, including liver cancer. A diagnosis of type 2 diabetes during follow-up was associated with a further increased risk of severe liver disease, regardless of BMI at the start of the study. This study included a very large population, and has used reliable sources of data for medical diagnoses and cause of death. But there are limitations to ...
Source: NHS News Feed - March 21, 2017 Category: Consumer Health News Tags: Obesity Cancer Source Type: news

Teens are getting liver damage from overeating
British teenagers are now being treated for cirrhosis of the liver caused by overeating. The disease, where the liver becomes scarred, lumpy and shrunken, is associated with alcoholism. (Source: the Mail online | Health)
Source: the Mail online | Health - March 18, 2017 Category: Consumer Health News Source Type: news

Julie G. Anderson Joins BioVie as Independent Director and Investor
BEVERLY, MA--(Healthcare Sales & Marketing Network) - BioVie Inc. (BIVI), a development-stage company focused on the discovery, development, and commercialization of innovative drug therapies for liver disease, is pleased to announce the appointment of Jul... Biopharmaceuticals, Personnel BioVie, cirrhosis, liver disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 15, 2017 Category: Pharmaceuticals Source Type: news

How Hepatitis Became A Hidden Epidemic In Africa
This article was originally published on The Conversation. Read the original article. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website. (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - March 10, 2017 Category: Consumer Health News Source Type: news

Liver Cirrhosis Tied to Increased Stroke Risk Liver Cirrhosis Tied to Increased Stroke Risk
A study challenges the notion that ischemic stroke does not occur in patients with liver cirrhosis and calls for heightened awareness of the risk for hemorrhagic stroke in these patients, researchers say.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - March 7, 2017 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Philips wins FDA clearance for ElastQ liver imaging tech
Royal Philips (NYSE:PHG) said today that it won 510(k) clearance from the FDA for its ElastQ imaging technology, which allows for simultaneous imaging and assessment of tissue stiffness to diagnose liver conditions such as hepatitis B and cirrhosis. The company’s technology uses shear wave elastography to focus sound waves and assess soft tissue stiffness, according to Philips. Traditionally, healthcare practitioners perform liver biopsies to determine the stage of liver disease and these procedures can be costly and painful. Philips touts its ultrasound technology as a non-invasive alternative to conventional liver ...
Source: Mass Device - February 27, 2017 Category: Medical Equipment Authors: Sarah Faulkner Tags: 510(k) Food & Drug Administration (FDA) Imaging Regulatory/Compliance Ultrasound Wall Street Beat Royal Philips Source Type: news

Virus passed through SEX could cause cirrhosis or 'silent killer' cancer
LIVER CANCER and cirrhosis are just two of the risks with can arise from contracting hepatitis B - a virus which can be spread through unprotected sex. (Source: Daily Express - Health)
Source: Daily Express - Health - February 17, 2017 Category: Consumer Health News Source Type: news

Simeprevir+Sofosbuvir in Patients With HCV Genotype 4 Simeprevir+Sofosbuvir in Patients With HCV Genotype 4
This study assessed the combination of simeprevir and sofosbuvir for 12 weeks in treatment-naive or -experienced HCV genotype 4-infected patients, with and without compensated cirrhosis.Alimentary Pharmacology & Therapeutics (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - February 16, 2017 Category: Transplant Surgery Tags: Gastroenterology Journal Article Source Type: news

The Impact of Infection by MDRAs in Patients With Cirrhosis The Impact of Infection by MDRAs in Patients With Cirrhosis
How prevalent are multi-drug resistant infections in patients with cirrhosis, and what is the impact on treatment and outcomes?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 9, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

High Rates of Hepatocellular Carcinoma After Hepatitis C Treatment High Rates of Hepatocellular Carcinoma After Hepatitis C Treatment
Patients treated with direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV)-related cirrhosis appear to have high rates of hepatocellular carcinoma (HCC). (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 8, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Gold standard monitoring of HCC in patients with cirrhosis is cost-effective
(Wiley) Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis. A new analysis indicates that following screening guidelines for HCC in cirrhotic patients is lifesaving and cost-effective compared with 'real life' monitoring. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 8, 2017 Category: Global & Universal Source Type: news

Risk of liver cancer is low in patients with cirrhosis
(Wiley) Although one of the most serious complications of cirrhosis is liver cancer, or hepatocellular carcinoma (HCC), an analysis of health records revealed that the 10-year incidence of HCC in UK patients with cirrhosis is 4 percent or lower. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 1, 2017 Category: Cancer & Oncology Source Type: news

Opioid Use, Gut Microbiota, and Cirrhosis Readmissions Opioid Use, Gut Microbiota, and Cirrhosis Readmissions
This study indicates that chronic opioid therapy in patients with cirrhosis may have an adverse effect on gut microbiota composition and functionality.Alimentary Pharmacology & Therapeutics (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - January 25, 2017 Category: Surgery Tags: Gastroenterology Journal Article Source Type: news

Liver Cirrhosis: Are implants an option?
This dental implant patient presented yesterday at the wax try in for the denture set up and informed me he was recently diagnosed with cirrhosis of the liver. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - January 24, 2017 Category: Dentistry Authors: osseonews Tags: Clinical Cases Surgical Source Type: news

Nuchal septations increase risk for fetal anomalies
Nuchal septations are a powerful independent risk factor for chromosomal fetal...Read more on AuntMinnie.comRelated Reading: Repeat fetal ultrasound screenings may be unnecessary Smoking adversely affects patellar, Achilles tendons 3D/4D ultrasound matures as it shows clinical value Contrast US boosts diagnostic power of breast ultrasound Spleen stiffness correlates with cirrhosis complication (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 19, 2017 Category: Radiology Source Type: news

Liver Cirrhosis Tied to Hepatocellular Cancer Recurrence Liver Cirrhosis Tied to Hepatocellular Cancer Recurrence
Compared with patients with a normal liver who undergo curative hepatectomy because of de novo hepatocellular carcinoma (HCC), those with liver cirrhosis may have a higher hepatocarcinogenic potential, researchers say.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - January 13, 2017 Category: Surgery Tags: Gastroenterology News Source Type: news

What Precautions Should A Childcare Center Take For A Child with Hepatitis C Infection?
Discussion It is estimated that 180 million people worldwide are infected with Hepatitis C (HCV) which includes ~11 million children. In the United States it is estimated that there were 30,500 acute HCV cases in 2014, and 2.7-3.9 million people with chronic HCV. Many infections are not identified. It is estimated that “…only 5-15% of HCV-infected children in the United States are identified.” Problems associated with HCV include acute hepatitis (including fever, malaise, dark-urine, abdominal pain, jaundice, appetite loss, nausea, emesis, clay-colored stools), acute fulminant hepatitis (not common in c...
Source: PediatricEducation.org - January 9, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Covert hepatic encephalopathy: can my patient drive? - Shaw J, Bajaj JS.
Liver cirrhosis is a public health problem and hepatic encephalopathy is one of its main complications, which can be either overt meaning thereby evident and readily diagnosed, or covert/minimal (covert hepatic encephalopathy-CHE) needing psychometric test... (Source: SafetyLit)
Source: SafetyLit - December 29, 2016 Category: Global & Universal Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

NICE focuses on improving treatment and diagnosis of liver disease
Almost 1.9 million harmful drinkers in England could be sent for scans for cirrhosis by their GPs to detect disease early so treatment and lifestyle changes are more effective. (Source: NHS Networks)
Source: NHS Networks - December 20, 2016 Category: UK Health Source Type: news