Oral Combo Tx Soars in HCV (CME/CE)
(MedPage Today) -- The 3D regimen cleared hepatitis C virus, even without ribavirin and in patients with cirrhosis. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 20, 2014 Category: Gastroenterology Source Type: news

HCV: Racial Differences in Progression to Cirrhosis and HCCHCV: Racial Differences in Progression to Cirrhosis and HCC
Are men and women with hepatitis C from certain racial backgrounds more at risk for developing cirrhosis and hepatocellular carcinoma? The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Magnetic resonance helps detect, quantify fat in liver
Excess weight causes important alterations in an organism, one of which affects liver function. Fat accumulates in the liver producing hepatic steatosis which can cause inflammation, fibrosis and cirrhosis. To date, the most reliable method for determining hepatic fat has been hepatic biopsy. Imaging techniques such as abdominal ecography detect, but are less precise for determining the quantity of fat. Now a study has shown that magnetic resonance is a good method -- better still than hepatic biopsy -- for detecting fats in the liver and for quantifying them. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 17, 2014 Category: Science Source Type: news

New Index Helps Predict Course of Early HCV CirrhosisNew Index Helps Predict Course of Early HCV Cirrhosis
A genomic signature, combined with bilirubin and platelet tests, can help identify patients with early hepatitis C virus (HCV) cirrhosis who are at high risk for complications, new research suggests. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 4, 2014 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Impact of Coffee on Liver DiseasesImpact of Coffee on Liver Diseases
This extensive new review examines the association of coffee consumption with liver diseases, such as cirrhosis, hepatitis, and fatty liver disease. What's the verdict? Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 15, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

High HCV Response Rates With Daclatasvir/AsunaprevirHigh HCV Response Rates With Daclatasvir/Asunaprevir
A combination of daclatasvir plus asunaprevir yielded high rates of sustained virological response (SVR) in treatment-naive patients with hepatitis C 1B infection, including those with cirrhosis, in a multinational phase III trial. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 7, 2014 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Model of viral lifecycle could help in finding a cure for hepatitis B
A new technique sustains hepatitis B in liver cells, researchers have discovered, allowing for the study of immune response and drug treatments. Around 400 million people worldwide are infected with the hepatitis B virus (HBV); of those, one-third will go on to develop life-threatening complications, such as cirrhosis and liver cancer. Although there is an effective HBV vaccine, only around 50 percent of people in some countries where the disease is endemic are vaccinated. A complete cure for the disease is very rare, once someone has been chronically infected. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 4, 2014 Category: Science Source Type: news

Minimum unit pricing to help ‘harmful drinkers’
Harmful drinkers with liver cirrhosis would be 200 times more affected by introducing minimum unit pricing for alcohol than low risk drinkers Hide related content:  Show related content read more (Source: Nursing in Practice)
Source: Nursing in Practice - August 4, 2014 Category: Nursing Authors: Lalah-Simone Springer Tags: Alcohol and drugs Substance misuse Editor ' s pick Latest News Source Type: news

Harmful drinkers would be affected 200 times more than low risk drinkers if a Minimum Unit Price was introduced
A new study of liver patients shows that a Minimum Unit Price policy for alcohol is exquisitely targeted towards the heaviest drinkers with cirrhosis. Researchers studied the amount and type of alcohol drunk by 404 liver patients, and also asked patients how much they paid for alcohol. They found that patients with alcohol related cirrhosis were drinking on average the equivalent of four bottles of vodka each week, and were buying the cheapest booze they could find. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 1, 2014 Category: Science Source Type: news

Introducing minimum unit price for alcohol would hit harmful drinkers
Alcohol-related cirrhosis patients ‘seek out the cheapest alcohol they can find’Related items from OnMedicaGovernment consultation into minimum unit alcohol pricing branded a shamMassive rise in alcohol related hospital admissions Chancellor urged to ‘crack down’ on cheap drinkMinimum price for alcohol announced in ScotlandMinimum pricing for alcohol ‘would cut deaths’ (Source: OnMedica Latest News)
Source: OnMedica Latest News - August 1, 2014 Category: UK Health Source Type: news

Preventing Mortality in Patients With Cirrhosis and HCVPreventing Mortality in Patients With Cirrhosis and HCV
What is the number needed to treat in order to prevent mortality and complications in cirrhotic patients with HCV genotype 1? Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 31, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Harmful drinkers would be affected 200 times more than low risk drinkers with an MUP
(University of Southampton) A new study of liver patients by the University of Southampton shows that a minimum unit price (MUP) policy for alcohol is exquisitely targeted towards the heaviest drinkers with cirrhosis. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 31, 2014 Category: Global & Universal Source Type: news

FibroTest/Fibrosure for Liver Fibrosis and Cirrhosis in HBVFibroTest/Fibrosure for Liver Fibrosis and Cirrhosis in HBV
How accurate and effective are noninvasive alternatives like FibroTest/Fibrosure in determining the extent of liver fibrosis in patients with chronic hepatitis B? The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 29, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Hepatitis C annual report
Hospital admissions from hepatitis C-related end stage liver disease have risen from 608 in 1998 to 2,390 in 2012, while deaths have risen from 98 in 1996 to 428 in 2012. Liver transplants first registrations where post-hepatitis C cirrhosis was an indication for transplant have quadrupled from 45 in 1996 to 188 in 2013. These figures are released as part of the Public Health England (PHE) annual report on hepatitis C in the UK. (Source: NHS Networks)
Source: NHS Networks - July 29, 2014 Category: UK Health Authors: Maria Axford Source Type: news

New oral drug regimens cure hardest-to-treat hepatitis C infected patients, could improve treatment uptake
Two new pill-only antiviral drug regimens could provide shorter, more effective treatment options with fewer side effects for the majority of patients infected with hepatitis C, even those most difficult to treat, according to the results of two studies. Around 150 million people worldwide have chronic hepatitis C virus (HCV) infection, a condition that is a major cause of liver cirrhosis and liver cancer. In the USA, numbers of people with HCV-related liver failure and liver cancer are expected to treble by 2030 because of low treatment rates. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 28, 2014 Category: Science Source Type: news

Probiotics in Cirrhosis: Do We Expect Too Much?Probiotics in Cirrhosis: Do We Expect Too Much?
Is there enough evidence that probiotics are effective in the treatment of cirrhosis? Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 4, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

'Supercooling' may extend life of transplant organs
Conclusion When organs are removed from a living body their cells immediately begin to die, meaning they need to be transplanted into the donor as soon as possible to give the best chances of a successful transplant. The number of people needing organ transplant always outnumbers the number of suitable matched donors available. So having a technique that could preserve organs for longer and potentially allow them to be transported across greater distances to suitable recipients could, as the researchers say, be a great breakthrough. This is especially important as it can often be difficult to find a suitably matched donor ...
Source: NHS News Feed - June 30, 2014 Category: Consumer Health News Tags: Medical practice Source Type: news

Forgotten In The Sovaldi Price Debate: Hep-C Patients And Healthcare Savings
?My sister is a Genome 1 Registered Nurse who was infected by a patient with HCV more than 30 years ago. She is already in mid-stage cirrhosis and, if she lived long enough, her only prospect was a liver transplant using her son as a donor. We are all grateful for Sovaldi, which she starts next week. Although her insurance covers 90%, Gilead will contribute all but the last $20.? (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 25, 2014 Category: Pharmaceuticals Authors: John LaMattina Source Type: news

Well: Ask Well: Diagnosing Fatty Liver
A reader asks: How do they diagnose fatty liver disease? What harm does it cause the body in its early stages, before cirrhosis, liver cancer and liver failure? (Source: NYT)
Source: NYT - June 25, 2014 Category: American Health Authors: By ANAHAD O'CONNOR Tags: Ask Well Liver medicine and health Cirrhosis Diabetes Featured Source Type: news

Well: Ask Well: Diagnosing Fatty Liver
A reader asks: How do they diagnose fatty liver disease? What harm does it cause the body in its early stages, before cirrhosis, liver cancer and liver failure? (Source: NYT Health)
Source: NYT Health - June 25, 2014 Category: Consumer Health News Authors: By ANAHAD O'CONNOR Tags: Ask Well Liver medicine and health Cirrhosis Diabetes Featured Source Type: news

Well: Ask Well: Diagnosing Fatty Liver
A reader asks: How do they diagnose fatty liver disease? What harm does it cause the body in its early stages, before cirrhosis, liver cancer and liver failure? (Source: NYT)
Source: NYT - June 25, 2014 Category: Nutrition Authors: By ANAHAD O'CONNOR Tags: Ask Well Liver medicine and health Cirrhosis Diabetes Featured Source Type: news

Melanoma is now fifth most common cancer in England
Figures show dramatic rise in rates of liver and skin cancer over past ten yearsRelated items from OnMedicaGP melanoma biopsy speeds referralMonitor people with cirrhosis for liver cancerMapping cancer risks Patients miss gravity of cancer symptomsHalf of all cancer patients now survive a decade (Source: OnMedica Latest News)
Source: OnMedica Latest News - June 23, 2014 Category: UK Health Source Type: news

Mayo Clinic Study Reverses Current Thought on Treatment of Cirrhosis
https://www.youtube.com/watch?v=dGd5cIM5U0Q&feature=youtu.be&hd=1 ROCHESTER, Minn. — Researchers at Mayo Clinic released a new study reversing current thought on the treatment of cirrhotic patients with type 2 diabetes. The study found that the continuation of metformin after a cirrhosis diagnosis improved survival rates among diabetes patients. Metformin is usually discontinued once cirrhosis is diagnosed because of concerns about [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 18, 2014 Category: Databases & Libraries Source Type: news

State of the Art: Treatment of Nonalcoholic SteatohepatitisState of the Art: Treatment of Nonalcoholic Steatohepatitis
Patients with NASH are at an increased risk for developing cirrhosis and hepatocellular carcinoma. How can clinicians best treat these patients to prevent these more serious diseases from occurring? Current Opinion in Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 17, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Probiotics prevent deadly complications of liver disease
Probiotics are effective in preventing hepatic encephalopathy in patients with cirrhosis of the liver, according to a new study. The investigators conducted trial with cirrhosis patients who showed risk factors for hepatic encephalopathy, but had yet to experience an obvious episode. When comparing treatment with probiotics versus placebo, the researchers found that the incidence of hepatic encephalopathy was lower in patients treated with probiotics. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 6, 2014 Category: Science Source Type: news

Probiotics prevent deadly complications of liver disease, study finds
Probiotics are effective in preventing hepatic encephalopathy in patients with cirrhosis of the liver, according to a new study. The investigators conducted trial with cirrhosis patients who showed risk factors for hepatic encephalopathy, but had yet to experience an obvious episode. When comparing treatment with probiotics versus placebo, the researchers found that the incidence of hepatic encephalopathy was lower in patients treated with probiotics. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 6, 2014 Category: Science Source Type: news

Probiotics prevent deadly complications of liver disease
(American Gastroenterological Association) Probiotics are effective in preventing hepatic encephalopathy in patients with cirrhosis of the liver, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 6, 2014 Category: Cancer & Oncology Source Type: news

Cirrhosis
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - May 28, 2014 Category: Journals (General) Source Type: news

Make the diagnosis, Sherlock!
This is a case recently reported in the Medical Journal of Australia.  A 50-year-old woman presented with a read, painful, scaling rash on her hand an forearms, and around her eyes. She reported that sun exposure aggravated the dermal symptoms. She also gave a history of intermittent diarrhea. Examination revealed a scaly hyperpigmented lesion on her upper chest, in the distribution of a broad collar. The patient was a smoker and said she consumed half a bottle of gin daily. The skin manifestations did not respond to antibiotics or steroids. Click on the following questions to reveal the answers. Was is the diagn...
Source: The Poison Review - May 22, 2014 Category: Toxicology Authors: Leon Tags: Medical dermatitis niacin deficiency pellagra Source Type: news

Researchers propose treating prison population to fight US hepatitis C epidemic
(University of California - Riverside) Nearly four million Americans may be infected with the hepatitis C virus, with many people unaware of their status. The virus can take decades to make those infected ill with cirrhosis, cancer or liver failure. Three researchers argue in the May 15 issue of the New England Journal of Medicine that America's oversized prison population provides a critical opportunity to tackle the US hepatitis C epidemic. One in six prisoners is infected with the virus. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 14, 2014 Category: Cancer & Oncology Source Type: news

Boceprevir Combo Helpful in Compensated HCV CirrhosisBoceprevir Combo Helpful in Compensated HCV Cirrhosis
In well-compensated cirrhotic patients with HCV-1, peginterferon/ribavirin along with boceprevir appears to have a generally favorable benefit-risk profile, according to pooled data from phase 3 studies. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - May 13, 2014 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

WHO calls on governments to do more to prevent alcohol-related deaths and diseases
12 May 2014 -- Worldwide, 3.3 million deaths in 2012 were due to harmful use of alcohol, says a new report launched by WHO today. Alcohol consumption can not only lead to dependence but also increases people’s risk of developing more than 200 diseases including liver cirrhosis and some cancers. In addition, harmful drinking can lead to violence and injuries. (Source: WHO news)
Source: WHO news - May 12, 2014 Category: Global & Universal Tags: alcohol [subject], injuries [subject], Press release [doctype], substance abuse [subject], violence [subject], Audio, Fact Sheets, media center, media centre, Notes for the Press, Photographs, Press Releases, statements, Visual, news release, press releas Source Type: news

VIDEO: PCPs fuzzy on HCC surveillance in cirrhosis
Read the full story on MD Consult: VIDEO: PCPs fuzzy on HCC surveillance in cirrhosis (Source: MD Consult: News: Top Stories)
Source: MD Consult: News: Top Stories - May 9, 2014 Category: Journals (General) Source Type: news

New Drug Combination Highly Effective For Hepatitis C
Hepatitis C, a bloodborne liver disease, primarily acquired via unscreened blood products or blood transfusions, IV drug use, or inadequate sterilization of medical equipment in the healthcare setting, can potentially result in a condition known as cirrhosis or scarring of the liver and lead to liver cancer. Hepatitis C represents the most common chronic viral infection in the US, ranging in severity from a mild illness lasting a few weeks to a serious, lifelong ailment. It is estimated that 130–150 million people globally have chronic hepatitis C infection, with about 3.5-4 million in the US alone, and nearly 350,0...
Source: Forbes.com Healthcare News - May 8, 2014 Category: Pharmaceuticals Authors: Robert Glatter, MD Source Type: news

Hepatocellular Carcinoma: Clinical Frontiers and PerspectivesHepatocellular Carcinoma: Clinical Frontiers and Perspectives
Hepatocellular carcinoma often develops in patients with cirrhosis. What treatment options, both surgical and medical, are available to treat this liver disease? Gut (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - May 7, 2014 Category: Gastroenterology Tags: Gastroenterology Journal Article Source Type: news

Screening May Help Boost Liver Cancer Survival Rates
Simple tests for people with scarring of the liver spot tumors early, researchers report Source: HealthDay Related MedlinePlus Pages: Cirrhosis, Liver Cancer, Ultrasound (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 7, 2014 Category: Consumer Health News Source Type: news

Liver cancer screening highly beneficial for people with cirrhosis
Liver cancer survival rates could be improved if more people with cirrhosis are screened for tumors using inexpensive ultrasound scans and blood tests, according to a review by doctors at UT Southwestern. (Source: UT Southwestern Medical Center News)
Source: UT Southwestern Medical Center News - May 5, 2014 Category: Hospital Management Source Type: news

Liver cancer screening highly beneficial for people with cirrhosis
(UT Southwestern Medical Center) Liver cancer survival rates could be improved if more people with cirrhosis are screened for tumors using inexpensive ultrasound scans and blood tests, according to a review by doctors at UT Southwestern Medical Center. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 5, 2014 Category: Cancer & Oncology Source Type: news

Critical end-stage liver disease discovery made
The discovery of an unknown cellular pathway has helped scientists and physicians better understand end-stage liver disease and offers a potential target for new therapeutics that could slow or even reverse the disease's progression. Although cirrhosis of the liver is most commonly associated with alcohol or drug abuse, the condition -- marked by scar tissue replacing healthy liver tissue -- also can result from viral hepatitis, obesity and diabetes, as well as certain inherited diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 25, 2014 Category: Science Source Type: news

Primary Biliary Cirrhosis (PBC)
Title: Primary Biliary Cirrhosis (PBC)Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 4/23/2014 2:58:18 PM (Source: MedicineNet Crohn's Disease General)
Source: MedicineNet Crohn's Disease General - April 23, 2014 Category: Gastroenterology Source Type: news

Drinking coffee reduces chances of dying from liver cirrhosis
(Source: NaturalNews.com)
Source: NaturalNews.com - April 22, 2014 Category: Consumer Health News Source Type: news

Triple Combination Works in Cirrhotic Hepatitis C PatientsTriple Combination Works in Cirrhotic Hepatitis C Patients
The all-oral antiviral regimen was highly effective and well tolerated in a hard-to-treat group of patients with hepatitis C genotype 1 and cirrhosis. Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - April 15, 2014 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

3D Combo Works in Cirrhotic HCV Patients, Too
LONDON (MedPage Today) -- A drug combination with striking efficacy in relatively healthy hepatitis C patients had similar outcomes in patients with compensated cirrhosis, a researcher said. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 14, 2014 Category: Gastroenterology Source Type: news

New hepatitis C drug treatment 'shows promise'
Conclusion Although designed as an RCT, the study had an analysis of drug effectiveness that becomes more like a single cohort of people receiving an active treatment, with no comparison arm. People were assigned to the five-drug combination or matching placebos for 12 weeks. During this time, the side effects in both treatment groups were monitored and these could be compared, with itching and anaemia occurring more commonly in the active treatment group. However, the double-blind drug treatment period was completed at 12 weeks and response outcomes were then assessed 12 weeks later. Twelve weeks later, the active treatm...
Source: NHS News Feed - April 14, 2014 Category: Consumer Health News Tags: Medication Medical practice Source Type: news

New hepatitis C drug treatment 'shows promise'
Conclusion Although designed as an RCT, the study had an analysis of drug effectiveness that becomes more like a single cohort of people receiving an active treatment, with no comparison arm. People were assigned to the five-drug combination or matching placebos for 12 weeks. During this time, the side effects in both treatment groups were monitored and these could be compared, with itching and anaemia occurring more commonly in the active treatment group. However, the double-blind drug treatment period was completed at 12 weeks and response outcomes were then assessed 12 weeks later. Twelve weeks later, the active treatm...
Source: NHS News Feed - April 14, 2014 Category: Consumer Health News Tags: Medication Medical practice Source Type: news

Obeticholic Acid Tx Tied to Clinical Benefit in PBC
LONDON (MedPage Today) -- The investigational compound obeticholic acid holds promise for people with primary biliary cirrhosis (PBC) -- the first new potential treatment in 2 decades, a researcher said here. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 13, 2014 Category: Gastroenterology Source Type: news

New Compound Tied to Clinical Benefit in PBC
LONDON (MedPage Today) -- The investigational compound obeticholic acid holds promise for people with primary biliary cirrhosis (PBC) -- the first new potential treatment in 2 decades, a researcher said here. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 13, 2014 Category: Gastroenterology Source Type: news

Mechanism, possible treatment, for immune suppression in liver disease uncovered
The mechanism that underlies the susceptibility of liver disease patients to life-threatening infection has been uncovered by medical scientists, who have also suggested a possible treatment to reverse immune suppression in these patients. Liver disease, or cirrhosis, patients are more than five times more likely to pick up infections in hospital than patients with other chronic conditions, due to reduced immunity which is a well-recognized feature of the disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 13, 2014 Category: Science Source Type: news

Hepatitis C treatment cures over 90 percent of patients with cirrhosis
Twelve weeks of an investigational oral therapy cured hepatitis C infection in more than 90 percent of patients with liver cirrhosis and was well tolerated by these patients, according to a new study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 12, 2014 Category: Science Source Type: news

Hepatitis C treatment cures over 90 percent of patients with cirrhosis
(University of Texas Health Science Center at San Antonio) Twelve weeks of an investigational oral therapy cured hepatitis C infection in more than 90 percent of patients with liver cirrhosis and was well tolerated by these patients, according to an international study that included researchers from UT Medicine San Antonio and the Texas Liver Institute. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 12, 2014 Category: Infectious Diseases Source Type: news