Psychoactive medications increase the risk of falls and fall-related injuries in hospitalized patients with cirrhosis - Tapper EB, Risech-Neyman Y, Sengupta N.
BACKGROUND & AIMS: Reducing or eliminating falls are a focus of patient safety programs as well as health policy. Falls are tied to hospital reimbursement. However, little is known about the risk of falls among hospitalized patients with cirrhosis or facto... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - April 5, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Liver injury in non-alcoholic steatohepatitis leads to a leaky gut
Non-alcoholic steatohepatitis (NASH), the more severe form of non-alcoholic fatty liver disease that can progress to liver fibrosis and cirrhosis, is associated with leakiness of the intestinal wall, which in turn may worsen liver disease, according to research. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 2, 2015 Category: Science Source Type: news

New HCV Drugs Cost-effective for Some With Genotypes 2 and 3New HCV Drugs Cost-effective for Some With Genotypes 2 and 3
At $1000 a pill, interferon-free drugs are a good value for patients with cirrhosis who have not benefited from interferon; if lower prices cannot be negotiated, new drugs should go to the sickest. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 31, 2015 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

New genetic link found for alcohol-related liver cirrhosis
In most people, any liver damage that might occur from drinking alcohol is reversible. However, in 25 to 30 percent of alcoholics what begins as accumulation of fat in the liver progresses to inflammation, fibrosis and ultimately irreversible cirrhosis, for which the only treatment is a liver transplant. A new study indicates that specific gene mutations might predispose some people to irreversible liver cirrhosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 30, 2015 Category: Science Source Type: news

Sofosbuvir Cost-Effective for Hepatitis C Genotype 2 or 3? Only in Certain Patients (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH Sofosbuvir-based therapy is cost-effective in patients with hepatitis C genotype 2 or 3 infection plus cirrhosis and in those who've previously been treated with interferon, according to a simulation study … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 30, 2015 Category: Primary Care Source Type: news

Alterations in Cerebral White Matter and Neuropsychology in Patients with Cirrhosis and Falls - Gómez-Ansón B, Román E, Fernández de Bobadilla R, Pires-Encuentra P, Díaz-Manera J, Núñez F, Martinez-Horta S, Vives-Gilabert Y, Pagonabarraga J, Kulisevsky J, Córdoba J, Guarner C, Soriano G.
BACKGROUND & AIM: Falls are frequent in patients with cirrhosis but underlying mechanisms are unknown. The aim was to determine the neuropsychological, neurological and brain alterations using magnetic resonance-diffusion tensor imaging (MR-DTI) in cirrhot... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - March 28, 2015 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Beta-blockers, PPIs, and Bacterial Infections in CirrhosisBeta-blockers, PPIs, and Bacterial Infections in Cirrhosis
Are patients taking beta-blockers and PPIs more prone to bacterial infections in the presence of cirrhosis and, if so, why? Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 23, 2015 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

UCLA public health researchers go to church to promote hepatitis B screening
UCLA-Kaiser Permanente Center for Health Equity To reach a vulnerable population largely unaware of the health risks, a team from the Fielding School for Public Health held small group discussions in more than 50 Los Angeles-area Korean churches. For the large Korean American-community in Los Angeles, chronic infection with the hepatitis B virus looms as a significant — and too often unspoken — health threat, associated with the highest rates of liver cancer for any ethnic group in Los Angeles. Knowing one’s hepatitis B status can be critical — it allows those who test HBV-negative t...
Source: UCLA Newsroom: Health Sciences - March 21, 2015 Category: Universities & Medical Training Source Type: news

Love Your Liver And Turn Back The Years
Today, I want to talk to you about how important it is to be nice to your liver – especially if you want to keep your body younger than your years. And I’m not talking about cutting out that nice bottle of Bordeaux you might share with a special dinner companion on a Saturday night or depriving yourself of that fine, 18-year-old single malt you love to savor every now then. Of course, I recommend that you always drink responsibly. But if you really want to look after your liver, my advice is to drop excess fat. In fact, at my wellness clinic, taking good care of your liver by staying lean is one of my key anti-...
Source: Al Sears, MD Natural Remedies - March 13, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging Nutrition DNA fat loss supplements toxins Source Type: news

WHO issues its first hepatitis B treatment guidelines
WHO today issued its first-ever guidance for the treatment of chronic hepatitis B, a viral infection which is spread through blood and body fluids, attacking the liver and resulting in an estimated 650 000 deaths each year – most of them in low- and middle-income countries. Worldwide, some 240 million people have chronic hepatitis B virus with the highest rates of infection in Africa and Asia. People with chronic hepatitis B infection are at increased risk of dying from cirrhosis and liver cancer. (Source: WHO news)
Source: WHO news - March 12, 2015 Category: Global & Universal Tags: hepatitis [subject], jaundice, hepatitis a, hepatitis b, hepatitis c, hepatitis e, hepatitis [subject], jaundice, hepatitis a, hepatitis b, hepatitis c, hepatitis e, Press release [doctype] Source Type: news

PPIs, Liver Disease, and Mortality in Patients With CirrhosisPPIs, Liver Disease, and Mortality in Patients With Cirrhosis
What does the latest research tell us about PPI use and the risk for severe liver disease and mortality in patients with cirrhosis? Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 9, 2015 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Cirrhosis Regression in HCV Patients After Antiviral TherapyCirrhosis Regression in HCV Patients After Antiviral Therapy
Do the majority of patients with cirrhosis who achieve a sustained virological response develop cirrhosis regression? This new study investigates. Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 2, 2015 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Finding the Patient With Primary Biliary CirrhosisFinding the Patient With Primary Biliary Cirrhosis
If you don't consider it, you might miss the diagnosis of this slowly progressive autoimmune disorder. Medscape Gastroenterology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 28, 2015 Category: Gastroenterology Tags: Gastroenterology Expert Column Source Type: news

Researchers wind up a 40 year old debate on betaretrovirus infection in humans
New light has been shed on primary biliary cirrhosis, a rare liver disease that affects up to one in 500 middle aged women. In a study, researchers demonstrate that patients with the disease are infected with human betaretrovirus -- a virus resembling a mouse mammary tumor virus. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 19, 2015 Category: Science Source Type: news

UAlberta researchers wind up a 40-year-old debate on betaretrovirus infection in humans
(University of Alberta Faculty of Medicine & Dentistry) Research from the University of Alberta is shedding new light on primary biliary cirrhosis, a rare liver disease that affects up to one in 500 middle-aged women. In a study published in the journal Alimentary Pharmacology and Therapeutics, Andrew Mason, a professor of medicine in the Department of Medical Microbiology and Immunology, proves that patients with the disease are infected with human betaretrovirus -- a virus resembling a mouse mammary tumor virus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2015 Category: Global & Universal Source Type: news

Learn about the impact of diet on diabetes, cancer and heart disease
The Nutrition Society’s next scientific conference on 25-26 March in Aberdeen, Scotland, will focus on Diet, Gene Regulation and Metabolic Disease, and brings together leading scientific speakers on these topics from around the world: Professor Donald B Jump, Nutrition Program, School of Biological and Population Health Sciences, Oregon State University, USA;    Professor Romano Regazzi, Vice-Director of the School of Medicine, Department of Fundamental Neurosciences, University of Lausanne, Switzerland; Professor Loranne Agius, Professor of Metabolic Biochemistry, Institute of Cellular Medicine, Newcastle ...
Source: The Nutrition Society - February 17, 2015 Category: Nutrition Authors: RB Source Type: news

Rwanda: Why You Must Test for Hepatitis
[New Times]It is more infectious than HIV. And like HIV, you can carry the Hepatitis virus for ages without knowing that you have it. But Hepatitis B and C are fatal and can lead to liver failure and death. If left untreated, Hepatitis can lead to cirrhosis, liver cancer, liver failure and death. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 16, 2015 Category: African Health Source Type: news

Smoking Causes More Kinds Of Deaths Than We Ever Thought
Breast cancer, prostate cancer, and even routine infections. A new report ties these and other maladies to smoking and says an additional 60,000 to 120,000 deaths each year in the United States are probably due to tobacco use. The study by the American Cancer Society and several universities, published in Thursday's New England Journal of Medicine, looks beyond lung cancer, heart disease and other conditions already tied to smoking, and the 480,000 U.S. deaths attributed to them each year. "Smokers die, on average, more than a decade before nonsmokers," and in the U.S., smoking accounts for one of every five de...
Source: Science - The Huffington Post - February 12, 2015 Category: Science Source Type: news

Daily Drinking May Raise Risk of Liver Cirrhosis, Study Warns
Title: Daily Drinking May Raise Risk of Liver Cirrhosis, Study WarnsCategory: Health NewsCreated: 1/27/2015 12:00:00 AMLast Editorial Review: 1/28/2015 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - January 28, 2015 Category: Nutrition Source Type: news

Daily Drinking May Raise Risk of Liver Cirrhosis, Study Warns
Everyday habits appear to matter more than lifetime consumption, research suggests (Source: WebMD Health)
Source: WebMD Health - January 27, 2015 Category: Consumer Health News Source Type: news

Daily Drinking May Raise Risk of Liver Cirrhosis
Everyday habits appear to matter more than lifetime consumption, research suggests Source: HealthDay Related MedlinePlus Pages: Alcoholism and Alcohol Abuse, Cirrhosis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - January 27, 2015 Category: Consumer Health News Source Type: news

Daily drinking increases risk of alcoholic cirrhosis
(Elsevier Health Sciences) Approximately 170,000 people die from alcoholic cirrhosis of the liver in Europe every year. Although alcohol is the most important risk factor, less is known about the significance of different patterns of drinking. Currently scientists believe that cirrhosis is a function of the volume of alcohol consumed irrespective of patterns of drinking. Investigators have now established that alcohol drinking pattern has a significant influence on the risk of cirrhosis and that daily drinking increases that risk compared with drinking less frequently. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 26, 2015 Category: Global & Universal Source Type: news

January 20th Webinar Topic: Fatty Liver Disease and Liver Transplantation
Webinar Topic: Fatty Liver Disease and Liver Transplantation: For Adults and Children, What Patients Need to Know Join us on Tuesday, January 20th, 12:00 p.m CT to discuss the management of fatty liver disease in adults & children. Also learn about liver transplantation as a treatment for advanced disease and cirrhosis. Click on Mayo Clinic Connect [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - January 15, 2015 Category: Databases & Libraries Source Type: news

Viekirax and Exviera for the Treatment of Chronic Hepatitis C Virus Infection
Viekirax (ombitasvir / paritaprevir / ritonavir) and Exviera (dasabuvir) is indicated for the treatment of genotype 1 chronic hepatitis C virus (HCV) infection and compensated cirrhosis. (Source: Drug Development Technology)
Source: Drug Development Technology - January 13, 2015 Category: Pharmaceuticals Source Type: news

Conatus Says Data Supports Moving Forward With Liver Disease DrugConatus Says Data Supports Moving Forward With Liver Disease Drug
Conatus Pharmaceuticals Inc said on Thursday initial results from small early stage trials supported continued development of its experimental drug for patients with cirrhosis and liver impairment. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - January 9, 2015 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Study: more people have liver cirrhosis than previously thought
(NaturalNews) Researchers from the Loyola University Health System have discovered that liver cirrhosis, which can lead to liver cancer and liver failure, is more common than previously thought. After examining information from the National Health and Nutrition Examination Survey... (Source: NaturalNews.com)
Source: NaturalNews.com - January 9, 2015 Category: Consumer Health News Source Type: news

Biliary Cirrhosis Therapeutic Pipeline Review H2 2014 Report at...
ReportsnReports.com adds “Biliary Cirrhosis - Pipeline Review, H2 2014” to its store. The report provides an overview of the Biliary Cirrhosis therapeutic pipeline.(PRWeb January 05, 2015)Read the full story at http://www.prweb.com/releases/2014-h2-biliary-cirrhosis/pipeline-review-market/prweb12422863.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - January 6, 2015 Category: Pharmaceuticals Source Type: news

Liver cirrhosis more common than previously thought, study finds
(Loyola University Health System) Cirrhosis of the liver is more common than previously thought, affecting more than 633,000 adults yearly. And surprisingly, 69 percent of the adults identified as possibly having cirrhosis may not know they have the disease. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 5, 2015 Category: Global & Universal Source Type: news

Liver cirrhosis more common than previously thought, study finds
Cirrhosis of the liver is more common than previously thought, affecting more than 633,000 adults yearly. And surprisingly, 69 percent of the adults identified as possibly having cirrhosis may not know they have this disease, researchers report. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 4, 2015 Category: Science Source Type: news

Mechanics of cells' long-range communication modeled by researchers
Interdisciplinary research is showing how cells interact over long distances within fibrous tissue, like that associated with many diseases of the liver, lungs and other organs. By developing mathematical models of how the collagen matrix that connects cells in tissue stiffens, the researchers are providing insights into the pathology of fibrosis, cirrhosis of the liver and certain cancers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 23, 2014 Category: Science Source Type: news

Viekira Pak Approved for Hepatitis C (FREE)
By Amy Orciari Herman Edited by André Sofair, MD, MPH The FDA on Friday approved a new, all-oral, interferon-free treatment for patients with hepatitis C genotype 1, including those with cirrhosis. Viekira Pak includes a combination ombitasvir/paritaprevir/ritonavir tablet (two tablets taken once daily) plus a dasabuvir tablet … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - December 22, 2014 Category: Primary Care Source Type: news

FDA approves Viekira Pak to treat hepatitis C
The U.S. Food and Drug Administration today approved Viekira Pak (ombitasvir, paritaprevir and ritonavir tablets co-packaged with dasabuvir tablets) to treat patients with chronic hepatitis C virus (HCV) genotype 1 infection, including those with a type of advanced liver disease called cirrhosis. (Source: Food and Drug Administration)
Source: Food and Drug Administration - December 19, 2014 Category: American Health Source Type: news

Liver Fibrosis Develops Early After HCV SeroconversionLiver Fibrosis Develops Early After HCV Seroconversion
Liver fibrosis develops early after hepatitis C virus (HCV) seroconversion and progresses quickly to cirrhosis in many patients, according to new findings. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 15, 2014 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Identifying the cellular origin of fibrosis
(Brigham and Women's Hospital) Researchers from Brigham and Women's Hospital have identified what they believe to be the cells responsible for fibrosis, the buildup of scar tissue. Fibrotic diseases, such as chronic kidney disease and failure, lung disease, heart failure and cirrhosis of the liver, are estimated to be responsible for up to 45 percent of deaths in the developed world. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 2, 2014 Category: Global & Universal Source Type: news

Ten-point plan to tackle liver disease published
"Doctors call for tougher laws on alcohol abuse to tackle liver disease crisis," The Guardian reports. But this is just one of 10 recommendations for tackling the burden of liver disease published in a special report in The Lancet.The report paints a grim picture of an emerging crisis in liver disease in the UK, saying it is one of the few countries in Europe where liver disease and deaths have actually increased rapidly over the last 30 years. It concludes with 10 recommendations to tackle the burden of liver disease.The media has approached the recommendations from many different angles, with many sources only ...
Source: NHS News Feed - November 27, 2014 Category: Consumer Health News Tags: Food/diet Lifestyle/exercise QA articles Source Type: news

GPs need more training to avoid missing liver disease
Late detection and high alcohol intake behind huge rise in liver morbidity and mortalityRelated items from OnMedicaHospitals missing chance to tackle alcohol problems and save livesBreakthrough in liver researchMonitor people with cirrhosis for liver cancerAlcohol linked to 40% rise in liver disease deathsHeavy drinkers will be eligible for liver transplants for the first time (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 27, 2014 Category: UK Health Source Type: news

Update on new treatments for liver diseases
Cirrhosis and nonalcoholic fatty liver disease are two serious liver conditions with limited pharmacological treatments. The December issues of Clinical Gastroenterology and Hepatology and Gastroenterology highlights important updates into treatments for these two debilitating diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 21, 2014 Category: Science Source Type: news

Update on new treatments for liver diseases
(American Gastroenterological Association) Cirrhosis and nonalcoholic fatty liver disease are two serious liver conditions with limited pharmacological treatments. The December issues of AGA's journals -- Clinical Gastroenterology and Hepatology and Gastroenterology -- highlight important updates into treatments for these two debilitating diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2014 Category: Global & Universal Source Type: news

New liver gives mother of three a life without pain
Mrs. Linss’ medical problem was diagnosed as primary biliary cirrhosis (PBC), a disease in which the bile ducts are damaged, causing bile to build up in the liver. (Source: UT Southwestern Medical Center News)
Source: UT Southwestern Medical Center News - November 20, 2014 Category: Hospital Management Source Type: news

Early-TIPSS Placement in Patients With Variceal BleedingEarly-TIPSS Placement in Patients With Variceal Bleeding
Does early-TIPSS placement improve rebleeding and reduce mortality, compared to standard management in high-risk patients with cirrhosis and variceal bleeding? Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 18, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Ledipasvir Sofosbuvir Combination Cuts Cirrhotic Hepatitis CLedipasvir Sofosbuvir Combination Cuts Cirrhotic Hepatitis C
Patients with chronic hepatitis C infection and compensated cirrhosis had a high rate of sustained viral response with the fixed-dose combination, with or without ribavirin. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 13, 2014 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Well-Controlled Hepatitis C No Dent on LifespanWell-Controlled Hepatitis C No Dent on Lifespan
Survival in patients with chronic hepatitis C virus infection and advanced fibrosis or cirrhosis who achieved sustained virological response is similar to that of the general population. Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - November 13, 2014 Category: Internal Medicine Tags: Gastroenterology News Source Type: news

HCV Combo Overcomes Cirrhosis, Tx Failure
(MedPage Today) -- Treatment times with costly drugs can be cut in half by adding ribavirin. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - November 12, 2014 Category: Gastroenterology Source Type: news

Liver Disease - Related Deaths Up Sharply From 1999 to 2016
Adults aged 25 to 34 show greatest relative increase in mortality, driven by alcoholic cirrhosis (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 11, 2014 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Internal Medicine, Oncology, Journal, Source Type: news

Patients With Cirrhosis Have Considerable Financial Burden
Lack of insurance, financial distress resulting in delayed medical care tied to lower odds of HCC surveillance (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 11, 2014 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Internal Medicine, Oncology, Pharmacy, Journal, Source Type: news

Transferring Liver Patients May Do More Harm Than Good
(MedPage Today) -- Moving patients with decompensated liver cirrhosis from hospital to liver transplant center has pitfalls. (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - November 9, 2014 Category: Journals (General) Source Type: news

Intercept Announces Additional Data for OCA in Primary Biliary Cirrhosis
(Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - November 9, 2014 Category: Pharmaceuticals Source Type: news

Hepatitis B vaccine’s efficacy in doubt
The vaccination aims to reduce the number of chronic carriers who could infect others and themselves develop liver cancers or cirrhosis later in life. (Source: The Economic Times)
Source: The Economic Times - November 7, 2014 Category: Consumer Health News Source Type: news

Sleep Disorders in Cirrhotics; How Can We Detect?Sleep Disorders in Cirrhotics; How Can We Detect?
Are sleep disorders common in patients with cirrhosis, and how can clinicians best diagnose and evaluate them? Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 24, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

3D Plus Ribavirin Improves Liver Function in Cirrhosis3D Plus Ribavirin Improves Liver Function in Cirrhosis
A novel interferon-free oral regimen leads to an improvement in early measures of liver function, according to a new analysis of the TURQUOISE-II study in hepatitis C patients with cirrhosis. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 23, 2014 Category: Consumer Health News Tags: Gastroenterology News Source Type: news