Smartphone app found to be valid tool in screening for minimal hepatic encephalopathy
(Virginia Commonwealth University) A smartphone app can quickly screen for cognitive dysfunction often found in patients with cirrhosis, according to a new Virginia Commonwealth University study. The cognitive dysfunction, known as minimal hepatic encephalopathy, has been difficult to diagnose. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 18, 2013 Category: Global & Universal Source Type: news

Acetaminophen Toxicity in an Alcoholic Man
Dramatically elevated liver enzyme elevations in this man with alcoholic cirrhosis and clouded sensorium suggest a hepatocellular rather than an obstructive cause. (Source: Consultant Live)
Source: Consultant Live - August 11, 2013 Category: Primary Care Source Type: news

Alcoholic Cirrhosis and Elevated Liver Enzymes: Your Dx?
Dramatically elevated aminotransferases may be the result of medication toxicity, acute viral hepatitis, or ischemic injury to the liver. Your assessment? (Source: Consultant Live)
Source: Consultant Live - August 9, 2013 Category: Primary Care Source Type: news

WHO urges governments to act on hepatitis threat
24 July 2013 -- On World Hepatitis Day (28 July), WHO is urging governments to act against the five hepatitis viruses that can cause severe liver infections and lead to 1.4 million deaths every year. Some of these hepatitis viruses, most notably types B and C, can also lead to chronic and debilitating illnesses such as liver cancer and cirrhosis, in addition to loss of income and high medical expenses for hundreds of millions of people worldwide. (Source: WHO news)
Source: WHO news - July 24, 2013 Category: Global & Universal Source Type: news

Prescribing Medications in Patients With CirrhosisPrescribing Medications in Patients With Cirrhosis
What should clinicians understand before prescribing medications to be used by patients with cirrhosis? Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 21, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Disruption Of Iron Uptake Receptor Identified In Hepatitis C
Hepatitis C virus (HCV) infects more than 170 million people worldwide. Approximately 80 percent of infections lead to chronic illness including fibrosis, cirrhosis, cancer and also hepatic iron overload. A new study completed by researchers at Loyola University Chicago Stritch School of Medicine reveals that HCV not only alters expression of the iron-uptake receptor known as transferrin receptor 1 (TfR1) but that TfR1 also mediates HCV entry... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 12, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

'Early death map' shows English health inequality
“North and South health divide: Chilling study reveals premature death is 'postcode lottery',” the Daily Mirror reports. The news is based on a new interactive map showing the variation in premature death rates across England. The Longer Lives map, created by the new organisation Public Health England, ranks 150 local authorities by their premature death rates (deaths occurring before age 75). The interactive map also enables users to compare these areas by five common causes of premature (and potentially preventable) deaths: cancer heart disease stroke lung diseases, such as chronic obstructive pu...
Source: NHS News Feed - June 11, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Cancer QA articles Source Type: news

Element of the week: thorium | video | @GrrlScientist
What does toothpaste, the Norse god of thunder and the word "pyrophoric" share in common?This week, we meet thorium, a chemical element with the symbol Th and atomic number 90. This element is a bit unusual since it is the first element we've met that was named for a character in Norse mythology: it was named in honour of the Norse god of thunder (and war), Thor. Swedish chemist Jöns Jakob Berzelius initially thought he had discovered this element in 1815 but soon realised that he had misidentified yttrium phosphate as being a new element, thorium. Berzelius apparently liked the name "thorium", sin...
Source: Guardian Unlimited Science - June 7, 2013 Category: Science Authors: GrrlScientist Tags: Blogposts guardian.co.uk Science Source Type: news

Blood Tests Diagnose Fibrosis, Cirrhosis in Chronic Hepatitis CBlood Tests Diagnose Fibrosis, Cirrhosis in Chronic Hepatitis C
Several blood tests, alone and in combination, can diagnose hepatitis C virus (HCV)-related fibrosis or cirrhosis, a systematic review indicates. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - June 4, 2013 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Blood Tests OK for Fibrosis Dx in Hep C (CME/CE)
(MedPage Today) -- Blood testing can accurately identify clinically significant fibrosis and cirrhosis in people with hepatitis C virus infection and may be an alternative to liver biopsy in some patients, a new study found. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 3, 2013 Category: Gastroenterology Source Type: news

How to Celebrate the Life of Slayer’s Jeff Hanneman
A fitting tribute to the life of Slayer’s Jeff Hanneman would be to not have a drink in his memory.read more (Source: Psychology Today Addiction Center)
Source: Psychology Today Addiction Center - May 23, 2013 Category: Addiction Authors: William Irwin, Ph.D. Tags: Addiction Creativity Media Philosophy alcoholism american medical association band mates bloody reign cause of death cirrhosis of the liver disease of alcoholism fasciitis flesh eating disease heavy drinker Jeff Hanneman joel Source Type: news

Adverse Events Common With Triple Therapy in HCV CirrhosisAdverse Events Common With Triple Therapy in HCV Cirrhosis
In cirrhotic patients, triple-therapy against hepatitis C virus (HCV) produces a high virological response rate, but at the cost of a high rate of serious adverse events, French researchers say. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 22, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Clinical Digest: Hepatitis C and Dietary Supplements
Hepatitis C, a contagious liver disease, is caused by the hepatitis C virus. People can get hepatitis C through contact with blood from a person who is already infected or, less commonly, through having sex with an infected person. The infection usually becomes chronic. Chronic hepatitis C often is treated with drugs that can eliminate the virus. This may slow or stop liver damage, but the drugs may cause side effects, and for some people, treatment is ineffective. Some people with hepatitis C also try complementary health approaches, especially dietary supplements. Several herbal supplements have been studied for hepatit...
Source: NCCAM Featured Content - May 13, 2013 Category: Complementary Medicine Authors: NCCAM Source Type: news

What Precautions Should Be Used for a Child Whose Parent is Hepatitis C Positive?
Discussion Hepatitis C virus (HCV) is a single-stranded RNA Flavivus that was first identified in 1989 and universal screening in the blood supply was begun in 1992 in the United States. Overall incidence of acute HCV in children under age 19 is 0.1 per 100,000. In adults, the transmission is mainly from contaminated blood and body fluids, primarily intravenous drug use. It is the most common reason for liver transplantation in adults. Of those that acquire the acute infection, about 70% go on to become chronically infected. Adults have a slow progression of their disease with 20% having cirrhosis within 20 years. Being ma...
Source: PediatricEducation.org - May 13, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Celiac Disease and Primary Biliary Cirrhosis: An Immune LinkCeliac Disease and Primary Biliary Cirrhosis: An Immune Link
What do scientists know about the connection between celiac disease and primary biliary cirrhosis, and how does this knowledge translate into treatement strategies for both diseases? Expert Review of Gastroenterology and Hepatology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - May 3, 2013 Category: Gastroenterology Tags: Gastroenterology Journal Article Source Type: news

Beta Blockers Ameliorate GI Permeability in CirrhosisBeta Blockers Ameliorate GI Permeability in Cirrhosis
Nonselective beta-blocker therapy improves gastrointestinal permeability, decreases intestinal bacterial translocation, and reduces variceal bleeding in patients with cirrhosis and esophageal varices. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 3, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

New Advances In The Management Of Patients With Cirrhosis
New data from clinical studies presented for the first time at the International Liver Congress™ 2013 provide new rationale for an old and established treatment option for portal hypertension.1 Additionally, spleen stiffness predicts the occurrence of clinical complications, which is of paramount importance in clinical practice.2 In patients with cirrhosis, increasing blood pressure in the abdominal circulatory system (known as portal hypertension) leads to potentially lethal complications which might be prevented with simple medical treatment... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 30, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Improved Screening Tests For Liver Cancer
New data from two clinical trials presented at the International Liver Congress™ 2013 demonstrate substantial improvements in the detection of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) using diagnostic urine tests. HCC is common throughout the world and most often develops as a late complication of chronic viral hepatitis or cirrhosis of any cause. The overall survival rate of HCC is poor and so screening for HCC offers the best hope for early detection, eligibility for treatment, and improved survival... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 29, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Triple Therapy Can Help in Advanced Hep C (CME/CE)
AMSTERDAM (MedPage Today) -- About 40% of people with advanced hepatitis C (HCV) can benefit from triple therapy even if they have cirrhosis and previous treatment failures, a researcher said here. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 28, 2013 Category: Gastroenterology Source Type: news

Hope For Improved Management Of Cirrhosis
New data from clinical studies presented for the first time at the International Liver Congress™ 2013 provide new rationale for an old and established treatment option for portal hypertension. Additionally, spleen stiffness predicts the occurrence of clinical complications, which is of paramount importance in clinical practice. In patients with cirrhosis, increasing blood pressure in the abdominal circulatory system (known as portal hypertension) leads to potentially lethal complications which might be prevented with simple medical treatment... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 27, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

New advances in the management of patients with cirrhosis
(European Association for the Study of the Liver) New data from clinical studies presented for the first time at the International Liver Congress™ 2013 provide new rationale for an old and established treatment option for portal hypertension. Additionally, spleen stiffness predicts the occurrence of clinical complications, which is of paramount importance in clinical practice. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 25, 2013 Category: Global & Universal Source Type: news

Research May Lead To Better Treatment For Liver Disease
A certain number of patients hospitalised for cirrhosis complications soon develop a syndrome characterised by acute liver failure and/or the failure of other vital organs (ACLF). This syndrome had no specific diagnostic criteria hitherto. In this prospective study, led by Dr Richard Moreau, INSERM Research Director (Mixed Research Unit 773 "Centre de Recherche biomedicale Bichat-Beaujon"; INSERM/Universite Paris Diderot) who is also a practitioner attached to the Hepatology Department of the Beaujon Hospital (AP-HP), researchers studied a cohort of 1343 patients from 12 European countries... (Source: Health News...
Source: Health News from Medical News Today - April 22, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Liver disease: Understanding it will enable the provision of better treatment
(INSERM (Institut national de la santé et de la recherche médicale)) A certain number of patients hospitalized for cirrhosis complications soon develop a syndrome characterized by acute liver failure and/or the failure of other vital organs. This syndrome had no specific diagnostic criteria hitherto. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 18, 2013 Category: Global & Universal Source Type: news

Scarring May Raise Death Risk from Fatty Liver Disease
Study looked at liver condition not tied to alcoholism Source: HealthDay Related MedlinePlus Pages: Cirrhosis, Liver Diseases (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 16, 2013 Category: Consumer Health News Source Type: news

Liver transplantation for patients with genetic liver conditions has high survival rate
This study is a first-of-its-kind, single-institution comparison of outcomes for both pediatric and adult patients undergoing liver transplantation for lethal genetic syndromes. Researchers found that children with genetic disorders that cause fibrosis, cirrhosis, and other liver conditions, which can affect other organs, have a good chance of still being alive five -- and even 20 years after a liver transplant operation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 5, 2013 Category: Global & Universal Source Type: news

Calling On The UK To Implement Minimum Pricing For Alcohol
According to WHO, liver cirrhosis accounts for 1.8% (i.e. 170,000) of all deaths in Europe. In recent years liver cirrhosis has become a serious health threat in some Western European countries such as Ireland and the United Kingdom, where over the last 10 years the associated mortality has increased . The European Association for the Study of the Liver (EASL) urges the UK government to press ahead with its proposed implementation of the minimum unit pricing of alcohol... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 17, 2013 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Do Nutritional Supplements Improve Cirrhosis Outcomes?Do Nutritional Supplements Improve Cirrhosis Outcomes?
A new meta-analysis couldn't prove that oral or enteral nutritional supplements help patients with cirrhosis, but the Canadian researchers remain hopeful. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 15, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

EASL calls on UK to tackle alcohol consumption problem through implementation of minimum pricing
(European Association for the Study of the Liver) EASL urges UK government to press ahead with proposed implementation of the minimum unit pricing of alcohol. EASL's most publication The burden of liver disease in Europe: a review of available epidemiological data highlights the fact that alcohol consumption is one the leading causes of cirrhosis in Europe. Alcohol is the main cause of liver disease, including liver cirrhosis, and there is a clear correlation between an increase in alcohol-related cirrhosis and increases in alcohol consumption. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 13, 2013 Category: Global & Universal Source Type: news

Acute Variceal Bleed Treatments in Cirrhotic PatientsAcute Variceal Bleed Treatments in Cirrhotic Patients
How do variceal bleed treatments work for patients with various liver diseases, including cirrhosis? The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 28, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

New Mouse Research May Lead To Liver Stem Cell Therapy For Chronic Liver Disease In Humans
For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique - until now... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 27, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Publication Of First Comprehensive Literature Review On The Burden Of Liver Disease In Europe: EASL
Major progress has been made in the past 30 years in the knowledge and management of liver disease, yet approximately 29 million Europeans still suffer from a chronic liver condition. The European Association for the Study of the Liver (EASL) has unveiled its new publication The burden of liver disease in Europe: a review of available epidemiological data. Key findings in the report suggest that alcohol consumption, viral hepatitis B and C and metabolic syndromes related to overweight and obesity are the leading causes of cirrhosis and primary liver cancer in Europe... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 25, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

OHSU scientists first to grow liver stem cells in culture, demonstrate therapeutic benefit
(Oregon Health & Science University) For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique -- until now. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 25, 2013 Category: Global & Universal Source Type: news

How Surprisingly Potent Hepatitis C Drug Works Revealed By Computer Modeling
A study by researchers from Los Alamos National Laboratory and a multinational team reveals how daclatasvir, a direct-acting antiviral agent in development for the treatment of hepatitis C virus (HCV), targets one of its proteins and causes the fastest viral decline ever seen with anti-HCV drugs - within 12 hours of treatment. Chronic infection with hepatitis C virus affects about 150 million people worldwide. It is the leading cause of cirrhosis, liver cancer and liver transplants and results in some 350,000 deaths worldwide every year... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 22, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

EASL publishes first comprehensive literature review on the burden of liver disease in Europe
(European Association for the Study of the Liver) Major progress has been made in the past 30 years in the knowledge and management of liver disease, yet approximately 29 million Europeans still suffer from a chronic liver condition.Key findings in the report suggest that alcohol consumption, viral hepatitis B and C and metabolic syndromes related to overweight and obesity are the leading causes of cirrhosis and primary liver cancer in Europe. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 21, 2013 Category: Global & Universal Source Type: news

Hepatitis C New Study On Drug Treatment In Vivo And In Vitro
Hepatitis C virus (HCV) infection affects about 4.1 million in the United States and is the primary cause of liver cirrhosis and liver cancer. Current therapy against HCV is suboptimal. Daclatasvir, a direct acting antiviral (DAA) agent in development for the treatment of HCV, targets one of the HCV proteins (i.e., NS5A) and causes the fastest viral decline (within 12 hours of treatment) ever seen with anti-HCV drugs... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

It Seems No One Ever Dies a Natural Death
When people die, it is not unusual to blame somebody—anybody.read more (Source: Psychology Today Relationships Center)
Source: Psychology Today Relationships Center - February 19, 2013 Category: Psychiatry & Psychology Authors: Fredric Neuman, M.D. Tags: Behavioral Economics Health Integrative Medicine Relationships acid indigestion bill of health brother cirrhosis dad death drugs dying elevator GERD heart attack hepatitis liver transplant magical thinking. nbsp nbsp nb Source Type: news

Early PBC prognosis advocated
Biochemical response to ursodeoxycholic acid at 6 months is a better predictor for primary biliary cirrhosis prognosis than the current standard of 1 year, study results suggest. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - February 19, 2013 Category: Gastroenterology Source Type: news

95 patients infected with hepatitis C linked to Chinese clinic
Hepatitis C causes liver disease which can range from a mild illness to a serious, lifelong condition that can lead to cirrhosis or liver cancer (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 5, 2013 Category: Consumer Health News Source Type: news

Featured in Journal Watch: Preventing Death from Septic Shock in Cirrhosis
(Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - February 3, 2013 Category: Primary Care Tags: Medical News Source Type: news

The Effects Of Binge Drinking On The Liver
Alcoholic liver disease (ALD) is characterized by a fatty liver, hepatitis, fibrosis, and cirrhosis. Binge drinking is on the rise worldwide, and is particularly common in the U.S. A review of studies addressing the effects of binge drinking on the liver underscores the complex interactions among various immune, signaling pathways, epigenetic, and metabolic responses of the liver to binge drinking. Results will be published in the April 2013 issue of Alcoholism: Clinical & Experimental Research and are currently available at Early View... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 24, 2013 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Harmful Cells May Have A Role To Play In Liver Repair, Study Suggests
Liver damage could be repaired by the same cells that harm the organ in the first place, a study suggests. The cells - called macrophages - cause tissue to become scarred, which can lead to cirrhosis of the liver. Scientists at the University of Edinburgh have now found that the macrophages also have a role in breaking down and getting rid of damaged tissue so that the normal liver structure and function is restored. Macrophages are found throughout the body and help fight infection by breaking down bacteria... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 18, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Pulmonary Complications of CirrhosisPulmonary Complications of Cirrhosis
The key pulmonary vascular complications of cirrhosis are comprehensively reviewed. Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 16, 2013 Category: Consumer Health News Tags: Gastroenterology Expert Column Source Type: news

The Importance Of Interleukin (IL)-28 For Hepatitis C Treatment
A metanalysis published in BioMed Central's open access journal BMC Medicine has confirmed that polymorphisms (SNP) in the gene coding for interleukin-28 (IL28B) influence natural hepatitis C viral (HCV) clearance and response to pegylated interferon-α plus ribavirin (PEG-IFN/RBV). Information about IL28B genotype could be used to provide personalized medicine and target treatment options effectively. Over 200 million people worldwide are chronically infected with hepatitis C virus (HCV) and about a quarter of these will go on to develop cirrhosis of the liver... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 8, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Anti-HBV Nucleos(t)ide Analogues in HBV/HCV CirrhosisAnti-HBV Nucleos(t)ide Analogues in HBV/HCV Cirrhosis
What is the most effective way to treat HBV/HCV chronic co-infections? Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 4, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

UPDATE: After liver transplant for HCV, better antiviral results with cyclosporine
NEW YORK (Reuters Health) - In patients transplanted for hepatitis C cirrhosis, the virus inevitably recurs. Now a new meta-analysis suggests that cyclosporine-based immunosuppression may be associated with a better response to antiviral therapy after transplant than tacrolimus-based protocols. (Source: Modern Medicine)
Source: Modern Medicine - January 2, 2013 Category: Journals (General) Source Type: news

After liver transplant for HCV, better antiviral results with cyclosporine
NEW YORK (Reuters Health) - In patients transplanted for hepatitis C cirrhosis, the virus inevitably recurs. Now a new meta-analysis suggests that cyclosporine-based immunosuppression may be associated with a better response to antiviral therapy after transplant than tacrolimus-based protocols. (Source: Modern Medicine)
Source: Modern Medicine - January 2, 2013 Category: Journals (General) Source Type: news

Increased risk of fractures seen in patients with cirrhosis
NEW YORK (Reuters Health) - Patients with cirrhosis face an increased risk of orthopedic fracture, researchers from Taiwan report. (Source: Modern Medicine)
Source: Modern Medicine - January 1, 2013 Category: Journals (General) Source Type: news