LR-M category tied to lower survival in HCC resection patients

Non-liver cancer-specific malignant lesions (LR-M) on CT or MRI are tied to lower overall survival in patients with solitary hepatocellular carcinoma (HCC) undergoing resection, a study published February 27 in Radiology found. Researchers led by Roberto Cannella, MD, from the University of Palermo in Italy also found that the presence of at least one non-targetoid feature is linked to increased recurrence risk, regardless of LI-RADS category. “Overall, our results confirm that the LR-M category should be considered in addition to pathology,” Cannella and colleagues wrote. The Liver Imaging Reporting and Data System (LI-RADS) and histopathologic features provide prognostic information to radiologists for evaluating patients with HCC. However, the researchers pointed out that it’s not well known whether LI-RADS is independently tied to survival. Cannella and co-authors explored these associations, focusing on LI-RADS categories and features and their potential ties to survival outcomes in patients with solitary resected HCC. The team included retrospective data from 360 patients with an average age of 64 years in its study. The patients were examined in three institutions and underwent preoperative contrast-enhanced CT and/or MRI between 2008 and 2019. For the study, three independent readers assessed the LI-RADS version 2018 categories and features. The team also recorded the following histopathologic features: World Health Organization (WHO) tumor grade, microvas...
Source: AuntMinnie.com Headlines - Category: Radiology Authors: Tags: CT MRI Source Type: news