Nonalcoholic fatty liver disease, commonly associated with diabetes, increases the risk of heart disease, and liver, colorectal, and breast cancers
(Natural News) In a new study that was published in the Journal of Hepatology, researchers were able to surmise that nonalcoholic fatty liver disease (NAFLD) is not only associated with hepatocellular carcinoma (HCC), but also to cancers that have nothing to do with the liver, such as colorectal and breast cancers. “NAFLD is a very... (Source: NaturalNews.com)
Source: NaturalNews.com - February 21, 2019 Category: Consumer Health News Source Type: news

Could whole grains, dietary fiber be associated with lower risk of liver cancer?
(JAMA Network) This   study used data for participants followed-up for 24 years as part of two well-known study groups to examine the association between whole grain and dietary fiber intake with the risk of hepatocellular carcinoma, a predominant form of liver cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2019 Category: Cancer & Oncology Source Type: news

Being overweight in adolescence may increase kidney cancer risk later in life
(Wiley) Being overweight has been linked with a higher risk of developing a form of kidney cancer called renal cell carcinoma (RCC) among adults, but it's unclear if this risk is present during adolescence. In an International Journal of Cancer study of adolescents who were followed for 37 years, researchers observed a trend for higher RCC risk with increasing body mass index during adolescence, where one-unit increase in body mass index conferred a six percent increased risk of RCC. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2019 Category: Cancer & Oncology Source Type: news

Pembrolizumab Plus Axitinib a New Standard in Metastatic RCC Pembrolizumab Plus Axitinib a New Standard in Metastatic RCC
First-line treatment with the anti-PD-1 immunotherapy pembrolizumab plus the VEGF-targeted tyrosine-kinase inhibitor axitinib extended overall survival and progression-free survival in patients with clear-cell metastatic renal cell carcinoma (mRCC), compared with the current standard of care, sunitinib, in the phase 3 KEYNOTE-426 trial.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - February 21, 2019 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news

Dr. McDermott on Single-Agent Pembrolizumab in Advanced RCC
In this video, David F. McDermott, MD, director of the Biologic Therapy Program at Beth Israel Deaconess Medical Center, discusses the use of single-agent pembrolizumab (Keytruda) in the treatment of patients with advanced non –clear cell renal cell carcinoma (RCC).02/20/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 20, 2019 Category: Urology & Nephrology Source Type: news

Pembrolizumab Active in Non-Clear Cell Kidney Cancer Pembrolizumab Active in Non-Clear Cell Kidney Cancer
Pembrolizumab monotherapy demonstrated promising antitumor activity when used as a first-line therapy agent in patients with non-clear cell renal carcinoma.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 20, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Glottic Carcinoma Can Be HPV - Related Disease in Young Adults
Cases of glottic carcinoma in patients aged 30 years or younger tested positive for high - risk HPV (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 20, 2019 Category: Cancer & Oncology Tags: Infections, Oncology, ENT, Pathology, Journal, Source Type: news

Combo Regimens Effective for Tx of Metastatic Renal Cell Cancer
WEDNESDAY, Feb. 20, 2019 -- For first-line therapy of metastatic renal cell carcinoma, pembrolizumab plus axitinib and avelumab plus axitinib both show improved survival versus sunitinib, according to two studies published online Feb. 16 in the New... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 20, 2019 Category: Pharmaceuticals Source Type: news

Glottic Carcinoma Can Be HPV-Related Disease in Young Adults
WEDNESDAY, Feb. 20, 2019 -- An increased incidence of glottic carcinoma related to human papillomavirus (HPV) has been documented in recent years among young patients, according to a study published online Jan. 27 in the Annals of Otology, Rhinology... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 20, 2019 Category: Pharmaceuticals Source Type: news

' Exciting Times' With Immunotherapy for Kidney Cancer'Exciting Times' With Immunotherapy for Kidney Cancer
New combinations with immunotherapy are going to change the standard of care in metastatic renal cell carcinoma, but questions remain, and there are technicalities to consider, according to some experts.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 19, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

ASCO GU 2019: First-line Pembrolizumab Monotherapy for Advanced Non-Clear Cell Renal Cell Carcinoma: Results from KEYNOTE-427 Cohort B
Keynote 427 Cohort B results demonstrate promising anti-tumor activity with first line pembrolizumab monotherapy in non-clear cell advanced RCC.02/19/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 19, 2019 Category: Urology & Nephrology Source Type: news

ASCO GU 2019: Analysis of Overall Survival Based on Early Tumor Shrinkage in the Phase III METEOR Study of Cabozantinib versus Everolimus in Advanced Renal Cell Carcinoma
During the Rapid Abstract Session on Renal Cell Cancer at the Annual ASCO GU 2019 meeting in San Francisco, CA, Dr. Duran presented on the analysis of overall survival (OS) based on early tumor shrinkage in the phase III METEOR study of cabozantinib (cabo) versus everolimus (eve) in advanced renal cell carcinoma (RCC).02/18/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 18, 2019 Category: Urology & Nephrology Source Type: news

ASCO GU 2019: Genetic Evolution of Metastatic Renal Cell Cancer
At ASCO GU in San Francisco, Dr. Samra Turajlic discussed the evolution of metastatic renal cell carcinoma.02/18/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 18, 2019 Category: Urology & Nephrology Source Type: news

Glottic Cancer Rates Rising in Young People Glottic Cancer Rates Rising in Young People
Glottic carcinoma rates in children and young adults have increased over the past three decades, according to a retrospective review.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 15, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Pembrolizumab Plus Axitinib vs Standard Treatment For mRCC
Treatment with pembrolizumab plus axitinib improved response and survival compared with sunitinib in patients with advanced, or metastatic clear-cell renal cell carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - February 13, 2019 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Direct - Acting Antivirals Cut Mortality in Chronic Hepatitis C
Mortality, hepatocellular carcinoma risk reduced after adjustment for potential confounders (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 12, 2019 Category: Cancer & Oncology Tags: Gastroenterology, Infections, Oncology, Pharmacy, Journal, Source Type: news

New Standard of Care for Metastatic Renal Cell Carcinoma New Standard of Care for Metastatic Renal Cell Carcinoma
Combination treatment with pembrolizumab and axitinib significantly improved survival outcomes as compared with sunitinib.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 12, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Direct-Acting Antivirals Cut Mortality in Chronic Hepatitis C
TUESDAY, Feb. 12, 2019 -- For adults with chronic hepatitis C virus (HCV) infection, direct-acting antivirals are associated with a reduced risk for mortality and hepatocellular carcinoma, according to a study published online Feb. 11 in The... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 12, 2019 Category: Pharmaceuticals Source Type: news

New diagnostic technique reveals a protein biomarker that accurately differentiates bladder cancer from benign inflammation
(Elsevier) Label-free digital pathology using infrared (IR) imaging with subsequent proteomic analysis for bladder cancer (BC) has revealed the first protein biomarker (AHNAK2) for BC. AHNAK2 differentiates between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type BC (carcinoma in situ) which is challenging to diagnose. A report in The American Journal of Pathology describes this new diagnostic procedure, which is label-free, automated, observer-independent, and as sensitive and specific as established histopathological methods. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 12, 2019 Category: Cancer & Oncology Source Type: news

Hep C Antivirals Tied to Lower Mortality and Cancer Risk
(MedPage Today) -- 52% drop in all-cause mortality, 34% drop in hepatocellular carcinoma cases (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - February 11, 2019 Category: Gastroenterology Source Type: news

Novel Therapies in Urothelial Carcinoma: Biomarker Approach Novel Therapies in Urothelial Carcinoma: Biomarker Approach
Which immunotherapies are showing promise for metastatic urothelial carcinomas?Annals of Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 11, 2019 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Immune Response Markers in Matched RCC Tissue Specimens Immune Response Markers in Matched RCC Tissue Specimens
Do renal clear cell carcinoma primary tumors and metastatic deposits demonstrate discordance in the expression of immune checkpoint proteins PD-L1, PD-1, and PD-L2?American Journal of Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 11, 2019 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Immunotherapy drug used as 1st-line therapy for Merkel cell carcinoma improved survival
(Louisiana State University Health Sciences Center) A multi-center phase II clinical trial investigating pembrolizumab as a first-line and programmed cell death-1 therapy in patients with advanced Merkel cell carcinoma reports lasting tumor control, generally manageable side effects and improved overall survival. Dr. Adam Riker led the study at LSU Health New Orleans. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2019 Category: International Medicine & Public Health Source Type: news

Immunotherapy appears better than chemotherapy for aggressive type of skin cancer
(Johns Hopkins Medicine) The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2019 Category: International Medicine & Public Health Source Type: news

Comparative study of renal cell carcinoma in patients less than 40 years of age and older age patients: A retrospective single-center study
Renal cell carcinoma (RCC) is typically found in the older age group between 50 and 70 years of age. However, diagnosis of renal cancer is increasing more rapidly in patients less than 40 years if age compared to older age patients.02/06/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 6, 2019 Category: Urology & Nephrology Source Type: news

Timing of brain metastases development in metastatic renal cell cancer patients treated with targeted therapies and survival outcomes: An Australian multicenter study
Targeted therapy (TT) has improved survival for metastatic renal cell carcinoma (mRCC). However, survival is usually limited if brain metastases (BMs) develop.02/06/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 6, 2019 Category: Urology & Nephrology Source Type: news

Mother, 26, dies following two-year battle with rare form of kidney cancer
Rhianna Ferguson, from Trafford, Manchester, died last week after suffering from renal medullary carcinoma, which is very rare and does not respond to treatment with chemotherapy. (Source: the Mail online | Health)
Source: the Mail online | Health - February 4, 2019 Category: Consumer Health News Source Type: news

Targeted and Immune Therapeutics for Basal Cell Cancer Targeted and Immune Therapeutics for Basal Cell Cancer
Review the use of hedgehog pathway inhibitors and other novel treatment options for metastatic basal cell carcinoma.Annals of Oncology (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - February 4, 2019 Category: Radiology Tags: Hematology-Oncology Journal Article Source Type: news

Crunching the data: New liver cancer subtypes revealed immunologically
(Tokyo Medical and Dental University) Tokyo Medical and Dental University (TMDU) researchers used substantial datasets on liver cancer patients to develop a new classification of hepatocellular carcinoma (HCC) into three distinct subgroups with different genetic, immunological, and clinical features. The findings of HCC subtypes related to metabolic disease, immunosuppression, or mitogenic/stem-cell-like tumors should aid the development of more targeted treatment and promote the fight against this devastating disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 1, 2019 Category: Biology Source Type: news

Avelumab promising cost-effective option for Merkel cell carcinoma
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - February 1, 2019 Category: Drugs & Pharmacology Source Type: news

First-Line TKIs Less Effective in Non-Clear-Cell Renal Cell Carcinoma
According to a study that was published in Urologic Oncology, patients with metastatic non-clear-cell renal cell carcinoma (nccRCC) have worse outcomes from first-line therapy with tyrosine kinase inhibitors (TKIs) than patients with metastatic clear-cell RCC (ccRCC).01/31/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - January 31, 2019 Category: Urology & Nephrology Source Type: news

Genetic causes of tumors in salivary glands
(University of Erlangen-Nuremberg) Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland. Until now, the molecular causes for the illness were unknown. Researchers at Universit ä tsklinikum Erlangen at FAU, the German Cancer Research Centre in Heidelberg and the Berlin Institute of Health have now been able to shed light on them. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 30, 2019 Category: Cancer & Oncology Source Type: news

Fibrosis Markers Tied to Mortality After Liver Cancer Surgery Fibrosis Markers Tied to Mortality After Liver Cancer Surgery
Noninvasive markers of fibrosis are associated with perioperative mortality and survival after liver resection for hepatocellular carcinoma, a retrospective study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 29, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

The efficacy and safety of sunitinib given on an individualised schedule as first-line therapy for metastatic renal cell carcinoma: A phase 2 clinical trial
Sunitinib is administered on a rigid schedule that may not be optimal for all patients. We hypothesised that toxicity-driven dose and schedule changes would optimise drug exposure and outcome for each patient.01/29/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - January 29, 2019 Category: Urology & Nephrology Source Type: news

Obesity Factors May Increase Kidney Cancer Risk
According to recent research conducted by Spectrum Health, certain factors such as diastolic blood pressure and fasting insulin were found to be associated with renal cell carcinoma.01/28/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - January 28, 2019 Category: Urology & Nephrology Source Type: news

BTG touts use of radiopaque drug-eluting bead
BTG (LON:BTG) said this month that an Australian patient was treated with its radiopaque drug-eluting bead. The DC Bead Lumi product is the first commercial drug-eluting bead that can be loaded with doxorubicin or irinotecan to treat tumors in patients with hepatocellular carcinoma and liver metastases from colorectal cancer, according to BTG. Get the full story at our sister site, Drug Delivery Business News. The post BTG touts use of radiopaque drug-eluting bead appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - January 28, 2019 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Featured Oncology Pharmaceuticals Wall Street Beat BTG Source Type: news

Direct-Acting Antivirals Not Tied to Liver Cancer Recurrence
FRIDAY, Jan. 25, 2019 -- Direct-acting antiviral (DAA) therapy is not associated with increased overall or early hepatocellular carcinoma (HCC) recurrence among patients with a previous complete response to HCC treatment, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 25, 2019 Category: Pharmaceuticals Source Type: news

Medical News Today: How aspirin may benefit some people with head and neck cancer
Regular use of aspirin or other NSAIDs increased survival in people with head and neck squamous cell carcinoma and alteration in the PIK3CA gene. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 25, 2019 Category: Consumer Health News Tags: Head and Neck Cancer Source Type: news

Study Investigates Survival Rates in Patients with Medullary Thyroid Carcinoma
Researchers conducted the first population-based study of an unselected MTC cohort compared with the general population. (Source: CancerNetwork)
Source: CancerNetwork - January 25, 2019 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

Utilizing US Features and BRAFV600E Mutation Status to Stratify Papillary Thyroid Carcinoma
Clinicians may be able to utilize this information as an effective preoperative tool to stratify risk and determine an initial surgical approach for patients with PTC. (Source: CancerNetwork)
Source: CancerNetwork - January 25, 2019 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

Study Investigates Survival Rates in Patients with Medullary Thyroid Carcinoma
Researchers conducted the first population-based study of an unselected MTC cohort compared with the general population. (Source: CancerNetwork)
Source: CancerNetwork - January 25, 2019 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

Utilizing US Features and BRAFV600E Mutation Status to Stratify Papillary Thyroid Carcinoma
Clinicians may be able to utilize this information as an effective preoperative tool to stratify risk and determine an initial surgical approach for patients with PTC. (Source: CancerNetwork)
Source: CancerNetwork - January 25, 2019 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

Low-risk cancers should be renamed 'indolent', oncologist urges
Birte Twisselmann (pictured) - an editor at The BMJ - was reassured following her basal cell carcinoma diagnosis when a colleague said 'well, it ’s not really cancer - you won’t die from it'. (Source: the Mail online | Health)
Source: the Mail online | Health - January 23, 2019 Category: Consumer Health News Source Type: news

Cutaneous metastasis of renal cell carcinoma: Fine needle aspiration provides rapid diagnosis
The diagnosis of cutaneous metastasis of renal cell carcinoma is challenging in a young person in absence of a prior history of cancer. In such situation, fine needle aspiration alone as a minimally invasive procedure can provide rapid, accurate and cost effective diagnosis, even in case of unknown primary.01/23/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - January 23, 2019 Category: Urology & Nephrology Source Type: news

Patient-reported outcomes of patients with advanced renal cell carcinoma treated with nivolumab plus ipilimumab versus sunitinib (CheckMate 214): a randomised, phase 3 trial
In the ongoing phase 3, CheckMate 214 trial, nivolumab plus ipilimumab improved overall survival compared with sunitinib in patients with intermediate or poor risk, previously untreated, advanced renal cell carcinoma.01/23/2019 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - January 23, 2019 Category: Urology & Nephrology Source Type: news

NHS England beats off drug company challenge
High Court dismisses AbbVie ’s case against NHS England’s hepatitis C programme Related items fromOnMedica England aims to be first in the world to eliminate hepatitis C Hepatocellular carcinoma risk, cirrhosis and hepatitis C New drive launched to trace hepatitis C patients Deaths from hepatitis C drop 11% in past year (Source: OnMedica Latest News)
Source: OnMedica Latest News - January 23, 2019 Category: UK Health Source Type: news

Topical Photodynamic Therapy for Basal Cell Carcinoma Topical Photodynamic Therapy for Basal Cell Carcinoma
How does topical photodynamic therapy compare in efficacy with other treatment options for low-risk basal cell carcinoma?The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 21, 2019 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Are Response Rates Predictive of Survival Outcome in HCC?
An analysis found that tumor response as assessed using modified RECIST criteria is an independent predictor of overall survival in hepatocellular carcinoma patients. (Source: CancerNetwork)
Source: CancerNetwork - January 20, 2019 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Amateur motorcyclist discovered he had mouth cancer after his wisdom tooth was removed
Andy Gale, 50, of  Bridgwater, Somerset was told he had stage-four squamous cell carcinoma in January 2014 after the wound left behind by a removed wisdom tooth failed to heal. (Source: the Mail online | Health)
Source: the Mail online | Health - January 17, 2019 Category: Consumer Health News Source Type: news