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A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment
The limited ability of cytotoxic T cells to infiltrate solid tumors hampers immune surveillance and the efficacy of immunotherapies in cancer. Adenosine accumulates in solid tumors and inhibits tumor-specific T cells. Adenosine inhibits T cell motility through the A2A receptor (A2AR) and suppression of KCa3.1 channels. We conducted three-dimensional chemotaxis experiments to elucidate the effect of adenosine on the migration of peripheral blood CD8+ T cells from head and neck squamous cell carcinoma (HNSCC) patients. The chemotaxis of HNSCC CD8+ T cells was reduced in the presence of adenosine, and the effect was greater o...
Source: Signal Transduction Knowledge Environment - April 24, 2018 Category: Science Authors: Chimote, A. A., Balajthy, A., Arnold, M. J., Newton, H. S., Hajdu, P., Qualtieri, J., Wise-Draper, T., Conforti, L. Tags: STKE Research Articles Source Type: news

NCCN: Screen for Liver Cancer in Patients at Risk NCCN: Screen for Liver Cancer in Patients at Risk
Hepatocellular carcinoma is a'bad actor'with a growing death toll in the United States and Europe; when possible, patients with risk factors should be screened.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 23, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

DAA Treatment for Patients With Hepatocellular Carcinoma DAA Treatment for Patients With Hepatocellular Carcinoma
What factors need to be considered when using DAAs for HCV in patients with HCC? Review recent findings surrounding indications, efficacy and outcomes associated with DAA treatment in these patients.Current Opinion in Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 23, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Vitamin A derivative selectively kills liver cancer stem cells
(RIKEN) Acyclic retinoid, an artificial compound derived from vitamin A, has been found to prevent the recurrence of hepatocellular carcinoma (HCC), the most common form of liver cancer. Now, in research published in Proceedings of the National Academy of Sciences, scientists have discovered that the compound targets one class of cancer stem cells, preventing them from giving rise to new tumors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 23, 2018 Category: Cancer & Oncology Source Type: news

Nivolumab/Ipilimumab Combo Approved for Advanced RCC
In a pivotal trial, combination of nivolumab and ipilimumab yielded improvement in OS and ORR of poor-risk RCC patients. (Source: CancerNetwork)
Source: CancerNetwork - April 19, 2018 Category: Cancer & Oncology Authors: Dylan Fisher Tags: Genitourinary Cancers News Renal Cell Carcinoma Source Type: news

Most Smokers With Head and Neck Cancer Have Tried to Quit
THURSDAY, April 19, 2018 -- Most active smokers with head and neck squamous cell carcinoma (HNSCC) have made one or more quit attempts, according to a study published online April 12 in JAMA Otolaryngology-Head& Neck Surgery. Samir S.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 19, 2018 Category: Pharmaceuticals Source Type: news

Sensus Healthcare inks multiple distro deals, launches global expansion project
Superficial radiation therapy device developer Sensus Healthcare (NSDQ:SRTSU) today released plans for a global expansion, including new distribution agreements in China, Germany, Mexico, Cuba and Costa Rica. Sensus makes low-energy photon X-ray systems for treating non-melanoma skin cancers, including basal cell and squamous cell carcinomas, and keloids. The Boca Raton, Fla.-based company refers to the technology as superficial radiation therapy, and claims that the tech has been sued to “effectively and safely treat oncological and non-oncological skin conditions.” “Following our new partnersh...
Source: Mass Device - April 19, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Distribution Oncology Sensus Healthcare LLC Source Type: news

Immunotherapy Prolongs Hepatocellular Carcinoma Survival Immunotherapy Prolongs Hepatocellular Carcinoma Survival
The benefits of immunotherapy with cytokine-induced killer cells continue to be seen in a follow-up extension study of patients with hepatocellular carcinoma.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 18, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

New Drug Combo Ups Survival in HER2/neu Uterine Serous Cancer
WEDNESDAY, April 18, 2018 -- For patients with human epidermal growth factor receptor 2 (HER2)/neu-positive uterine serous carcinoma, adding intravenous trastuzumab to treatment with carboplatin-paclitaxel is associated with increased... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 18, 2018 Category: Pharmaceuticals Source Type: news

FDA approves combination for advanced renal cell carcinoma
The approvals were based on CheckMate 214 (NCT02231749), a randomized open-label trial. Patients with previously untreated advanced RCC received nivolumab (3 mg/kg) plus ipilimumab (1 mg/kg) every 3 weeks for 4 doses followed by nivolumab monotherapy (3 mg/kg) every 2 weeks, or sunitinib 50 mg daily for 4 weeks followed by 2 weeks off every cycle.04/17/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - April 17, 2018 Category: Urology & Nephrology Source Type: news

Antibiotics Reduced Efficacy of Checkpoint Inhibitors in RCC, NSCLC
Antibiotics administered within 30 days of starting immunotherapy reduced both PFS and OS for patients with advanced RCC and NSCLC. (Source: CancerNetwork)
Source: CancerNetwork - April 16, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Genitourinary Cancers News Renal Cell Carcinoma Source Type: news

FDA Approves IO Combo for Advanced Renal Cell Cancer FDA Approves IO Combo for Advanced Renal Cell Cancer
The approval of the nivolumab and ipilimumab combination provides a new first-line treatment option for a segment of patients with advanced renal cell carcinoma.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

Trastuzumab Effective in Uterine Serous Carcinoma (CME/CE)
(MedPage Today) -- In patients overexpressing HER2, a 5-month boost in PFS when added to carboplatin-paclitaxel (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 14, 2018 Category: Hematology Source Type: news

Inhibiting metabolism found to be effective in treating aggressive form of lung cancer
FINDINGSResearchers from UCLA and Long Beach Memorial Medical Center have found that two targeted therapies could be more effective if used in combination to treat squamous cell carcinomas of the lung. The two drugs, MLN128 and CB-839, individually target the metabolism of key nutrients glucose and glutamine, respectively, prohibiting the cancer from switching metabolic gears between glucose (a simple sugar) and glutamine (an amino acid) to tap vital sources of energy. This switch enables the cancer cells to adapt their metabolism and evade treatments.BACKGROUNDNon-small cell lung cancer makes up about 85 percent of all lu...
Source: UCLA Newsroom: Health Sciences - April 13, 2018 Category: Universities & Medical Training Source Type: news

US study reports dramatic reduction in likelihood of liver transplantation in patients with hepatoce
(European Association for the Study of the Liver) ILC 2018: Although hepatocellular carcinoma is now the leading indication for liver transplantation in the USA, the probability of patients receiving a transplant has declined significantly in recent years. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2018 Category: International Medicine & Public Health Source Type: news

Selective internal radiation therapy (SIRT) fails to extend survival in the SORAMIC study palliative cohort
(European Association for the Study of the Liver) ILC 2018: The addition of SIRT to sorafenib in patients with advanced hepatocellular carcinoma was associated with no overall survival benefits compared with sorafenib alone, but may offer benefits in some subgroups of patients (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 13, 2018 Category: Cancer & Oncology Source Type: news

Inhibiting metabolism found to be effective in treating aggressive form of lung cancer
(University of California - Los Angeles Health Sciences) Researchers from UCLA and Long Beach Memorial Medical Center have found that two targeted therapies could be more effective if used in combination to treat squamous cell carcinomas of the lung (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 12, 2018 Category: Cancer & Oncology Source Type: news

Screening for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis achieving sustained virological response is likely to be cost effective
(European Association for the Study of the Liver) A Canadian study suggests that biannual or annual ultrasound screening for HCC is likely to be cost effective after a sustained virological response in those with hepatitis C-related cirrhosis, but not in those with advanced fibrosis without cirrhosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 12, 2018 Category: Cancer & Oncology Source Type: news

Sensitive new assay detects hepatitis B infection in single liver cells and serum
(Elsevier) Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples. This assay can be used to diagnose HCC at an earlier stage to manage treatment more effectively. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 12, 2018 Category: International Medicine & Public Health Source Type: news

Drop in Thyroidectomy Rates for Thyroid Carcinoma Drop in Thyroidectomy Rates for Thyroid Carcinoma
The rates of upfront total thyroidectomy and completion thyroidectomy for well-differentiated thyroid carcinoma (WDTC) have decreased since implementation of the updated 2015 American Thyroid Association guidelines.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - April 10, 2018 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Nivolumab/Ipilimumab Combo Bests Sunitinib in Advanced RCC
A phase III study by Dr. Robert Motzer and colleagues in NEJM found significantly higher OS and ORRs with the immunotherapy combination. (Source: CancerNetwork)
Source: CancerNetwork - April 9, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Immuno Oncology News Renal Cell Carcinoma Source Type: news

Man Tells 7th Circuit Judge Erred When Making Disability Determination
CHICAGO - A man who suffering from invasive basal cell carcinoma in the right ear tells the Seventh Circuit U.S. Court of Appeals in a Jan. 19 brief that a federal judge in Illinois erred when finding that he was not entitled to total disability benefits from his insurer because he cannot complete the duties that his work requires (Henry Fiorentini v. Paul Revere Life Insurance Co., No. 17-3137, 7th Cir.). (Source: LexisNexis® Mealey's™ Disability Insurance Legal News)
Source: LexisNexis® Mealey's™ Disability Insurance Legal News - April 9, 2018 Category: Medical Law Source Type: news

Payments to doctors linked to prescription practices for two cancer types
(UNC Lineberger Comprehensive Cancer Center) Compared to physicians who didn't receive any payments, those who received general payments for meals and lodging from a drug manufacturer had higher odds of prescribing that company's particular drug for metastatic renal cell carcinoma and for chronic myeloid leukemia. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 9, 2018 Category: Cancer & Oncology Source Type: news

First-Line Avelumab/Axitinib Encouraging in Advanced RCC
First-line combination therapy with the PD-L1 inhibitor avelumab and the VEGFR TKI axitinib yielded antitumor activity in previously untreated RCC. (Source: CancerNetwork)
Source: CancerNetwork - April 5, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Genitourinary Cancers News Renal Cell Carcinoma Source Type: news

NIH researchers use genomics to set squamous cell carcinomas apart from other cancers
Results could advance treatments for head and neck and other cancers. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - April 5, 2018 Category: American Health Source Type: news

Combinations: The Future of Renal Cell Carcinoma Treatment?
Renal cell carcinoma (RCC) is the most common form of kidney cancer, with an estimated 65,340 patients expected to be diagnosed in 2018 in the United States alone. Nearly a third of those patients will be diagnosed with the advanced or metastatic disease.04/05/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - April 5, 2018 Category: Urology & Nephrology Source Type: news

Nivolumab, ipilimumab combination improves advanced renal cell carcinoma survival
Nivolumab plus ipilimumab improved OS and objective response rates compared with sunitinib among patients with intermediate- and poor-risk advanced renal-cell carcinoma, according to findings published in The New England Journal of Medicine.04/04/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - April 4, 2018 Category: Urology & Nephrology Source Type: news

TIVO-1 Crossover: Tivozanib Active for Advanced RCC
Compared with sorafenib, tivozanib significantly improved PFS and OS, and yielded significantly higher ORRs, a crossover analysis of TIVO-1 found. (Source: CancerNetwork)
Source: CancerNetwork - April 4, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Tags: News Renal Cell Carcinoma Source Type: news

IFN-free Chronic HCV Therapy With DAAs and Risk for HCC IFN-free Chronic HCV Therapy With DAAs and Risk for HCC
Does IFN-free therapy with direct-acting antivirals alter the short-term risk for hepatocellular carcinoma in patients with cirrhosis?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 3, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Colleen's Dream Foundation funds ovarian cancer clinical trial
(The Translational Genomics Research Institute) Colleen's Dream Foundation, a Scottsdale-based nonprofit dedicated to supporting ovarian cancer research, recently awarded Translational Genomics Research Institute (TGen) $450,000 to fund a clinical trial for a newly developed ovarian cancer drug treatment. TGen, based in Phoenix, alongside an international team of collaborators, discovered a mutation in a gene known as SMARCA4, which drives a specific type of extremely aggressive ovarian cancer known as Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 3, 2018 Category: Cancer & Oncology Source Type: news

Thyroidectomy Rates Lower After Guideline Implementation
MONDAY, April 2, 2018 -- Implementation of the 2015 American Thyroid Association guidelines on surgery for well-differentiated thyroid carcinoma was associated with a significant decrease in the rates of both up-front total thyroidectomy and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 2, 2018 Category: Pharmaceuticals Source Type: news

Does Trastuzumab Plus Carbo/Paclitaxel Up PFS in Advanced HER2+ Uterine Carcinoma?
At SGO 2018, an early study showed ‘encouraging’ PFS with trastuzumab added to combination carboplatin/paclitaxel for advanced HER2/neu-overexpressing uterine serous carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - March 30, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Tags: Gynecologic Cancers News Conferences/SGO Source Type: news

New Standard of Care in Advanced Renal Cell Carcinoma? New Standard of Care in Advanced Renal Cell Carcinoma?
Combination immunotherapy significantly improved overall survival as compared to standard care with sunitinib as first-line therapy in patients with intermediate- and poor-risk disease.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 29, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Resection Bests Chemoembolization in Selected Liver Cancer Patients Resection Bests Chemoembolization in Selected Liver Cancer Patients
Resection offers survival benefits in carefully selected patients with intermediate-to-advanced hepatocellular carcinoma (HCC), researchers in Korea suggest.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 29, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Reduced Overall Survival for Alcohol-Related Liver Cancer
WEDNESDAY, March 28, 2018 -- Reduced overall survival (OS) is seen for patients with alcohol-related hepatocellular carcinoma (HCC), according to a study published online March 28 in Cancer. Charlotte E. Costentin, M.D., from the Public Hospital... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 28, 2018 Category: Pharmaceuticals Source Type: news

Dietary fibre for the prevention of recurrent colorectal adenomas and carcinomas
This Cochrane Review has led to a practice changing update on DynaMed Plus. It concludes that dietary fiber with wheat bran, ispaghula husk, or high fiber sources of food might increase risk of colorectal cancer in patients with history of adenomatous polyps. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 28, 2018 Category: Consumer Health News Source Type: news

Everolimus Plus Letrozole Effective in Endometrial Carcinoma
Findings from the GOG-3007 study suggest everolimus plus letrozole might be effective in advanced persistent or recurrent endometrial carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - March 27, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Tags: Endometrial Cancer News Conferences/SGO Source Type: news

Accurately identifying aggressive head and neck cancers
(Case Western Reserve University) Case Western Reserve University's Center for Computational Imaging and Personalized Diagnostics (CCIPD) is leading a partnership working toward the first clinical trials to determine the aggressiveness of-and appropriate treatment for-certain head and neck cancers.Head and neck cancers (squamous cell carcinomas or HNSCC) represent more than half-a-million cases and 300,000 deaths a year, making them the sixth-leading cancer worldwide, according to the World Health Organization. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 27, 2018 Category: Cancer & Oncology Source Type: news

Treatment Options Expanding in Renal Carcinoma
First- and second-line treatment of clear cell RCC has changed dramatically, Dr. Eric Jonasch said during the NCCN Annual Conference in Orlando. (Source: CancerNetwork)
Source: CancerNetwork - March 26, 2018 Category: Cancer & Oncology Authors: Roxanne Nelson Tags: Conferences/NCCN News Renal Cell Carcinoma Source Type: news

EU committee backs dosing changes for Bristol-Myers Squibb ’ s immunotherapy
A committee for the European Union’s pharmaceutical regulatory agency backed changes to the dosing schedule for Bristol-Myers Squibb‘s (NYSE:BMY) Opdivo cancer drug, the company touted today. The Committee for Medicinal Products for Human Use recommended that the European Commission approve a dosing schedule of 480-mg infused over 60 minutes every four weeks as an option for patients with advanced melanoma and previously-treated renal cell carcinoma. The committee also backed a shorter dosing option of 240-mg infused over 30 minutes every two weeks for Opdivo’s six approved monotherapy indications in...
Source: Mass Device - March 26, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Oncology Pharmaceuticals Regulatory/Compliance Wall Street Beat Bristol-Myers Squibb Co. Source Type: news

Incidence of Merkel Cell Carcinoma Rising Sharply
The incidence of Merkel cell carcinoma, an aggressive neuroendocrine skin cancer, has grown rapidly since the disease was first described in 1972. (Source: CancerNetwork)
Source: CancerNetwork - March 23, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Tags: News Skin Cancer Source Type: news

Women With DCIS Who Are at Low Risk for Recurrence Identified Women With DCIS Who Are at Low Risk for Recurrence Identified
Women with ductal carcinoma in situ (DCIS) who are at low risk for disease recurrence after conservative breast surgery and radiotherapy, and whose treatment could be reduced, have been identified.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 22, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Hurricane Katrina survivor beats five bouts of adrenal gland cancer
Charlotte Strecker, 46, of Tyler, Texas, was diagnosed with stage 3 adrenal carcinoma five times before beating the cancer in May 2005. (Source: the Mail online | Health)
Source: the Mail online | Health - March 22, 2018 Category: Consumer Health News Source Type: news

Zimbabwe:33% of Cancers Aids Related
[263Chat] Aids related cancers namely Kaposi Sarcoma, Cervical Cancer, Non-Hodgkins Lymphoma and Squamous Cell Carcinoma of the conjunctiva continue to occupy high positions in cancer rankings, according to Zimbabwe National Cancer Registry report. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 22, 2018 Category: African Health Source Type: news

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
During metastasis, malignant cells escape the primary tumor, intravasate lymphatic vessels, and reach draining sentinel lymph nodes before they colonize distant organs via the blood circulation. Although lymph node metastasis in cancer patients correlates with poor prognosis, evidence is lacking as to whether and how tumor cells enter the bloodstream via lymph nodes. To investigate this question, we delivered carcinoma cells into the lymph nodes of mice by microinfusing the cells into afferent lymphatic vessels. We found that tumor cells rapidly infiltrated the lymph node parenchyma, invaded blood vessels, and seeded lung ...
Source: ScienceNOW - March 22, 2018 Category: Science Authors: Brown, M., Assen, F. P., Leithner, A., Abe, J., Schachner, H., Asfour, G., Bago-Horvath, Z., Stein, J. V., Uhrin, P., Sixt, M., Kerjaschki, D. Tags: Medicine, Diseases reports Source Type: news

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice
Lymph node metastases in cancer patients are associated with tumor aggressiveness, poorer prognoses, and the recommendation for systemic therapy. Whether cancer cells in lymph nodes can seed distant metastases has been a subject of considerable debate. We studied mice implanted with cancer cells (mammary carcinoma, squamous cell carcinoma, or melanoma) expressing the photoconvertible protein Dendra2. This technology allowed us to selectively photoconvert metastatic cells in the lymph node and trace their fate. We found that a fraction of these cells invaded lymph node blood vessels, entered the blood circulation, and colon...
Source: ScienceNOW - March 22, 2018 Category: Science Authors: Pereira, E. R., Kedrin, D., Seano, G., Gautier, O., Meijer, E. F. J., Jones, D., Chin, S.-M., Kitahara, S., Bouta, E. M., Chang, J., Beech, E., Jeong, H.-S., Carroll, M. C., Taghian, A. G., Padera, T. P. Tags: Medicine, Diseases reports Source Type: news

Managing Ductal Carcinoma In Situ in the Era of Genomic Profiling
At the 2018 Miami Breast Cancer Conference, Dr. Patrick Borgen presented information related to gene expression profiling as a tool for managing DCIS. (Source: CancerNetwork)
Source: CancerNetwork - March 20, 2018 Category: Cancer & Oncology Authors: Patrick I. Borgen, MD Tags: Breast Cancer Conference Report Conferences/MBCC Source Type: news

Scientists caution that a rare childhood liver cancer can spread to the brain
(Rockefeller University) A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer spreads to the brain from the liver. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 19, 2018 Category: International Medicine & Public Health Source Type: news

Response and Development of Immune-Related Adverse Events in an 83-Year-Old Man With Metastatic Urothelial Cancer
An 83-year-old man was diagnosed with multiple low-grade transitional cell carcinomas over a 6-year period. A surveillance cystoscopy in year 7 showed high-grade noninvasive papillary urothelial carcinoma in the bladder trigone. A CT urogram showed a soft-tissue mass with diffuse enhancement in the lower pole of the left kidney, concerning for malignancy. (Source: CancerNetwork)
Source: CancerNetwork - March 15, 2018 Category: Cancer & Oncology Authors: Daniel P. Petrylak, MD Karishma K. Mehra, MD Tags: Bladder Cancer Genitourinary Cancers Oncology Journal Source Type: news

Poor Adherence to Hepatocellular Carcinoma Surveillance Poor Adherence to Hepatocellular Carcinoma Surveillance
In this study, the current adherence rates to HCC surveillance guidelines are examined.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 15, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news