CCR Grand Rounds: Immunotherapy of Liver Cancer: From Bench to Bedside and Back to the Bench
CCR Grand Rounds“ Immunotherapy of Liver Cancer: From Bench to Bedside and Back to the Bench ”
Tim F. Greten, M.D.
Deputy Chief, Thoracic and GI Malignancies Branch
Co-Director, NCI CCR Liver Cancer Program
Center for Cancer Research, NCI
Dr. Greten is a physician-scientist who uses his medical expertise in gastroenterology, hepatology and medical oncology along with his research expertise in tumor immunology to develop novel treatments for patients with cancer. He heads a research team to study the tumor microenvironment in the li ver in the context of hepatocellular carcinoma, cholangiocarcinoma and liver metasta...
Source: Videocast - All Events - September 13, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar Series: Development of targeted and immune-based therapies for urothelial carcinomas and rare genitourinary tumors
Dr. Apolo ’ s work has focused on the development of targeted therapies, with a focus on angiogenesis, MET inhibitors, and immunotherapies for the treatment of urothelial cancer and rare genitourinary tumors, and to further our understanding of the pathways driving these diseases. She has investigated the patterns of oncogenic tyrosine-kinase pathway-related alterations in bladder cancer for targeted therapy approaches and has demonstrated the innate and adaptive immunomodulatory properties of cabozantinib. From these mechanisms, she has conducted pioneering research into novel therapies for bladder, kidney, and rare gen...
Source: Videocast - All Events - September 26, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
CC Grand Rounds :The Advantages of Studying a Rare Cancer at the NIH, Lessons from Merkel Cell Carcinoma.
CC Grand Rounds :The Advantages of Studying a Rare Cancer at the NIH, Lessons from Merkel Cell CarcinomaFor more information go tohttps://cc.nih.gov/about/news/grcurrent.htmlAir date: 9/15/2021 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 17, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Human Oncogenic Viruses: Nature, Discovery, and Running Around in Circles
Wednesday Afternoon Lecture Series
Annual George Khoury Lecture
Dr. Chang is Distinguished Professor of Pathology in the Cancer Virology Program, University of Pittsburgh Cancer Institute. Her laboratory performs basic and applied research on viral oncogenesis with efforts focused in three areas: Merkel cell carcinoma and Merkel cell polyomavirus, the latter of which she discovered; Kaposi ’ s sarcoma-associated herpesvirus, the most common AIDS-associated malignancy; and new pathogen discovery.
Seven viruses collectively comprise an important cause of cancer, particularly in less-developed countries and under conditions...
Source: Videocast - All Events - May 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Human Oncogenic Viruses: Nature and Discovery
This is the annual George Khoury Lecture. Speaker Yuan Chang, M.D., University of Pittsburgh, performs basic and applied research on viral oncogenesis with efforts focused in the following three areas. Merkel cell carcinoma and Merkel cell polyomavirus: We recently discovered a new human polyomavirus, that we call Merkel cell polyomavirus (MCV). This virus is etiologically associated with a rare, but one of the most clinically aggressive skin cancers in humans. We are currently involved in the primary characteristics of this virus including transcript mapping, transforming properties, origin replication, transmission, and ...
Source: Videocast - All Events - February 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
The Case for BK Polyomavirus as a Cause of Bladder Cancer
NCI ’ s Center for Cancer Research (CCR) Grand Rounds
Dr. Buck ’ s lab studies polyomaviruses. A great majority of healthy adults chronically shed
polyomavirus virions in their urine and from the surface of their skin. Although these lifelong infections generally aren't known to cause symptoms in healthy individuals, under conditions of immune impairment polyomaviruses can cause disease. For example, BK polyomavirus (BKV) causes kidney and bladder damage in organ transplant patients, while its close relative JCV causes a lethal brain disease in patients on immunosuppressive therapies and in individuals suffering from ...
Source: Videocast - All Events - March 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Rear Admiral (Upper Half) Richard W. Childs Flag Promotion Ceremony
The United States Public Health Service Flag Promotion ceremony for Rear Admiral (RADM) Richard W. Childs, promoted to RADM Upper Half O-8 in January 2020, is being webcast live on 3/27/2020 from Masur Auditorium. Richard Childs, MD serves as the Clinical Director of the National Heart, Lung, and Blood Institute (NHLBI) at the National Institutes of Health (NIH). He was commissioned in the USPHS Commissioned Corps as a Lieutenant in 1995 when joined the NCI as an Oncology Fellow. Following fellowship training, he was appointed a tenure-track investigator in the Hematology Branch of the NHLBI where he continues to conduct r...
Source: Videocast - All Events - February 24, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Mining the Unexplored Cancer Kinome for Novel Therapeutic Targets in Squamous Cell Carcinomas
NCI ’ s Center for Cancer Research (CCR) Grand Rounds
Cancer genomic sequencing has significantly impacted the understanding of the temporal and spatial genetic alterations that lead to tumorigenesis. This information enables the development of targeted therapies that result in durable and less toxic responses in patients. In regard to kinases, the biomedical community has focused research efforts on approximately 200 kinases among the 538 kinases present in the human kinome, yet siRNA screens and cancer genomic studies indicate that the vast majority of these unexplored kinases (approximately 300) are implicated in canc...
Source: Videocast - All Events - December 9, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Neal D. Shore, MD, FACS - Advancing the Management of Urothelial Cancer With Immuno-Oncology and Targeted Approaches: Key Concepts for Urology Professionals on the Front Lines of Care
Go online to PeerView.com/XNW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The therapeutic landscape of advanced urothelial carcinoma of the bladder has undergone significant transformation in the last 2 years, with the emergence of immune checkpoint inhibitors as an essential component of the treatment armamentarium. Extensive research is also focused on newer approaches, such as antibody-drug conjugates and FGFR inhibitors, against actionable targets on urothelial cancer cells. This rapid expansion in the field poses several challenges for urologists and other hea...
Source: Peerview CME/CE Video Podcast - Internal Medicine International - June 19, 2019 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Jorge A. Marrero, MD, MS - Surveying the View From the Driver ’s Seat in Hepatocellular Carcinoma: Bringing Into Focus Hepatology’s Key Role in Guiding HCC Care Down the Path to Improved Outcomes
Surveying the View From the Driver’s Seat in Hepatocellular Carcinoma: Bringing Into Focus Hepatology’s Key Role in Guiding HCC Care Down the Path to Improved Outcomes (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - January 11, 2019 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Jorge A. Marrero, MD, MS - Surveying the View From the Driver ’s Seat in Hepatocellular Carcinoma: Bringing Into Focus Hepatology’s Key Role in Guiding HCC Care Down the Path to Improved Outcomes
Surveying the View From the Driver’s Seat in Hepatocellular Carcinoma: Bringing Into Focus Hepatology’s Key Role in Guiding HCC Care Down the Path to Improved Outcomes (Source: Peerview CME/CE Video Podcast - Internal Medicine International)
Source: Peerview CME/CE Video Podcast - Internal Medicine International - January 11, 2019 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Jorge A. Marrero, MD, MS - Surveying the View From the Driver ’s Seat in Hepatocellular Carcinoma: Bringing Into Focus Hepatology’s Key Role in Guiding HCC Care Down the Path to Improved Outcomes
Surveying the View From the Driver’s Seat in Hepatocellular Carcinoma: Bringing Into Focus Hepatology’s Key Role in Guiding HCC Care Down the Path to Improved Outcomes (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - January 11, 2019 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Riccardo Lencioni, MD, FSIR, EBIR - At the Intersection of Local and Systemic Therapy in the Management of Hepatocellular Carcinoma: Preparing for the Next Evolution in Multimodal Treatment
At the Intersection of Local and Systemic Therapy in the Management of Hepatocellular Carcinoma: Preparing for the Next Evolution in Multimodal Treatment (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - May 28, 2018 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Ghassan Abou-Alfa, MD, MBA - New Options, Emerging Combinations in Advanced Hepatocellular Carcinoma: Are Management Approaches Poised For Transformation?
New Options, Emerging Combinations in Advanced Hepatocellular Carcinoma: Are Management Approaches Poised For Transformation? (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - April 13, 2018 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Clinicopathologic Grand Rounds: Clinical Cases from the NIH Clinical Center: Targeting the Genetic and Metabolic Basis of Fumarate Hydratase-Deficient Kidney Cancer: Hereditary Leiomyomatosis and Renal Cell Carcinoma
For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 5/31/2017 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 15, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video
