SUMOylated IL-33 in the nucleus stabilizes the transcription factor IRF1 in hepatocellular carcinoma cells to promote immune escape | Science Signaling
Antitumor immunity against liver cancer is impaired by SUMOylation of intracellular IL-33. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 14, 2023 Category: Science Source Type: news
Novel PET Imaging Agent Accurately IDs Clear Cell Renal Cancers
(MedPage Today) -- An investigational PET imaging agent -- zirconium-89 (89Zr)-deferoxamine (DFO)-girentuximab -- identified clear cell renal cell carcinoma (ccRCC) with high sensitivity and specificity, according to results from the phase... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 13, 2023 Category: Hematology Source Type: news
Benefits Persist for Lenvatinib, Pembrolizumab in Renal Cell Cancer
MONDAY, March 13, 2023 -- For patients with advanced renal cell carcinoma, progression-free survival and overall survival are improved with lenvatinib plus pembrolizumab versus sunitinib, according to a study published in the March issue of The... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 13, 2023 Category: Pharmaceuticals Source Type: news
Key Abstracts in Renal Cell Carcinoma From ASCO GU 2023 Key Abstracts in Renal Cell Carcinoma From ASCO GU 2023
Key data in renal cell carcinoma from ASCO GU 2023 include phase 3 results on girentuximab and updates of CheckMate 9ER and COSMIC-313, which examined combination therapies in the frontline setting.Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 10, 2023 Category: Consumer Health News Tags: None ReCAP Source Type: news
New BAP1 Finding Could Be Key to Regulating Mesothelioma
Mesothelioma is a rare cancer most often caused by exposure to asbestos fibers. Our researchers at the University of Hawaii Cancer Center have discovered how asbestos causes mesothelioma, which we linked mainly to the protein HMGB1.
After several years of studying a unique mesothelioma epidemic in Cappadocia, Turkey, we noted that in certain families, up to 50% of family members developed mesothelioma. We demonstrated that susceptibility to mesothelioma was transmitted genetically from one generation to the next.
Following this discovery, several U.S. families with multiple mesothelioma cases contacted us...
Source: Asbestos and Mesothelioma News - March 9, 2023 Category: Environmental Health Authors: Fran Mannino Tags: Clinical Trials/Research/Emerging Treatments Mesothelioma Source Type: news
Joe Biden's Basal Cell Carcinoma
(MedPage Today) -- Last month, President Biden had a skin lesion removed from his chest. White House physician Kevin O'Connor, DO, is now reporting that the biopsy results of the lesion confirmed that the growth was a basal cell carcinoma (BCC... (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - March 8, 2023 Category: Dermatology Source Type: news
Taking a Break From TKIs Unlikely to Shorten Survival Taking a Break From TKIs Unlikely to Shorten Survival
A unique study in patients with renal cell carcinoma on tyrosine kinase inhibitors (TKIs) shows that taking a break from the drugs is feasible and cost-effective.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 7, 2023 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Genomic Sequencing Predicts Risk of Kidney Cancer Relapse Genomic Sequencing Predicts Risk of Kidney Cancer Relapse
Twelve genetic mutations in clear-cell renal cell carcinoma may predict which patients will experience recurrence; they could also help personalize adjuvant treatment, researchers say.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 7, 2023 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Biden's Skin Cancer; 'Butt Lift' Deaths Continue; Arrest Warrant for TB Patient
(MedPage Today) -- Note that some links may require subscriptions.
President Biden's doctor, Kevin O'Connor, DO, said the skin lesion removed from the president's chest was a basal cell carcinoma, a common type of skin cancer. (AP)
The White... (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - March 6, 2023 Category: Dermatology Source Type: news
President Biden Has Skin Cancer Removed From Chest, No Further Treatment Needed
MONDAY, March 6, 2023 – A lesion that was found and removed from President Joe Biden’s chest during his recent physical was determined to be a common type of skin cancer known as basal cell carcinoma.
“All cancerous tissue was successfully... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 6, 2023 Category: General Medicine Source Type: news
Long-Term Benefit From Nivolumab Plus Cabozantinib in RCC Long-Term Benefit From Nivolumab Plus Cabozantinib in RCC
First-line nivolumab plus cabozantinib continues to show superiority to sunitinib in the treatment of patients with advanced advanced renal cell carcinoma (RCC).Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 3, 2023 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Mutational Signature Indicates Risk of Kidney Cancer Recurrence
DNA sequencing can identify mutations that predict recurrence of renal cell carcinoma and may help low-risk patients avoid unnecessary treatment, a study finds. (Source: The Scientist)
Source: The Scientist - March 1, 2023 Category: Science Tags: News & Opinion Source Type: news
Alembic Pharma gets USFDA nod to market generic cancer drug
Docetaxel Injections are indicated for breast cancer, non-small cell lung cancer, castration-resistant prostate cancer, gastric adenocarcinoma and squamous cell carcinoma of head and neck. According to IQVIA data, Docetaxel injection has an estimated market size of USD 11 million in the US market. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 1, 2023 Category: Pharmaceuticals Source Type: news
Liver Fibrosis Among Relatives of Mexican Americans With HCC Liver Fibrosis Among Relatives of Mexican Americans With HCC
Mexican Americans are disproportionately affected by obesity and metabolic syndrome. Does hepatocellular carcinoma increase the familial risk for liver fibrosis in this population?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 28, 2023 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Hepatocellular Carcinoma and Hepatitis C Virus Treatments Hepatocellular Carcinoma and Hepatitis C Virus Treatments
This review elucidates the pathogenesis of chronic HCV-induced hepatocellular carcinoma, discussing the relationship between hepatic carcinogenesis and viral eradication by antivirals.Journal of Viral Hepatitis (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - February 27, 2023 Category: Infectious Diseases Tags: Gastroenterology Journal Article Source Type: news
