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Bone Health Drug Inhibits Mesothelioma Tumor Growth
A drug used to treat bone disease and high blood calcium levels may carry benefits as part of a combination treatment for malignant pleural mesothelioma, a recent study concluded. Researchers at the University of Alabama at Birmingham Comprehensive Cancer Center conducted a pilot study testing the effects of zoledronic acid — a bisphosphonate, or bone health drug, marketed as Reclast and Zometa — against a small group of patients with unresectable pleural mesothelioma. The study, published in the June edition of Lung Cancer: Targets and Therapy journal, was a follow-up to preclinical research showing zoledron...
Source: Asbestos and Mesothelioma News - July 20, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: bone disease treatment keytruda mesothelioma treatments Muhammad Omer Jamil reclast treating malignant pleural mesothelioma University of Alabama at Birmingham Comprehensive Cancer Center Zoledronic acid zometa Source Type: news

Asbestos Found in Children ’ s Makeup
Justice, a national retail chain marketed to young girls, has stopped selling a cosmetics product after discovering it contained talc contaminated with asbestos fibers. The government-licensed Scientific Analytical Institute (SAI) in Greensboro, North Carolina, confirmed the asbestos contamination after testing the product as part of a Durham-based WTVD-TV news investigation. The tainted product was Just Shine Shimmer Powder, which the company stopped selling at stores and removed from its website, according to a Tuesday post on its Facebook page. “Our suppliers are required to produce all products in compliance wit...
Source: Asbestos and Mesothelioma News - July 19, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: asbestos contaminates makeup asbestos in children's makeup asbestos in makeup asbestos in products asbestos in talcum powder asbestos in toys makeup with asbestos Source Type: news

Mesothelioma Clinical Trial Combines Immunotherapy Drugs
Dr. Tawee Tanvetyanon at the Moffitt Cancer Center in Tampa rarely sounds this enthused about the future prospects for patients with pleural mesothelioma. Finally, he has something promising to offer. Tanvetyanon is the principal investigator of a much-anticipated phase II clinical trial involving an immunotherapy drug combination with considerable potential for extending survival. “This is exciting. We now can offer something with realistic hope,” he told Asbestos.com. “We haven’t had anything like this for mesothelioma in a long time. I really look forward to speaking with these patients now.&rdqu...
Source: Asbestos and Mesothelioma News - July 13, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Abramson Cancer Center Aduro Biotech CRS-207 Dr. Tawee Tanvetyanon FDA approval Keytruda improving mesothelioma prognosis Merck mesothelioma chemotherapy mesothelioma clinical trials mesothelioma immunotherapy moffitt cancer center m Source Type: news

Asbestos Type Has No Effect on Mesothelioma Latency Period
New research from scientists in Germany sheds more light on the unusually long latency period associated with mesothelioma and other asbestos-related diseases. The study, published earlier this year in the European Respiratory Journal, is the first to track the presence of asbestos fibers in lung tissue over time. Mesothelioma has one of the longest latency periods of any cancer. It typically takes anywhere from 20 to 50 years after a person’s initial exposure to asbestos before symptoms arise. Using the German Mesothelioma Register, researchers at Ruhr-University Bochum discovered the volume of asbestos fibers in...
Source: Asbestos and Mesothelioma News - July 11, 2017 Category: Environmental Health Authors: Matt Mauney Tags: amosite amphibole asbestos exposure asbestos fiber burden asbestos fibers in lungs biopersistence of asbestos bronchoalveolar lavage Chrysotile asbestos Chrysotile asbestos fibers European Respiratory Journal German Mesothelioma Regist Source Type: news

SMART Protocol for Mesothelioma Adds Immunotherapy
In conclusion, we demonstrated the importance of the immune system in the benefit of clinical protocols using…radiation followed by surgery.” The post SMART Protocol for Mesothelioma Adds Immunotherapy appeared first on Mesothelioma Center - Vital Services for Cancer Patients & Families. (Source: Asbestos and Mesothelioma News)
Source: Asbestos and Mesothelioma News - July 6, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: emerging treatments for mesothelioma immunotherapy for mesothelioma SMART mesothelioma SMART protocol mesothelioma smart protocol mix with immunotherapy Source Type: news

BAP1 Mesothelioma Mutation Focus of Upcoming Clinical Trial
Researchers at the University of Hawaii believe they are close to a fix for the genetic mutation that makes certain people more susceptible to developing mesothelioma cancer and more resistant to chemotherapy. Dr. Michele Carbone, director of thoracic oncology at the UH Cancer Center, said the BAP1 genetic mutation his research first uncovered in 2011 will be key to future prevention and treatment of mesothelioma. “I do not like to make promises,” Carbone told Asbestos.com. “But our record shows that we’ve always delivered more than we planned for. We have a pretty good idea how to fix it.” Hi...
Source: Asbestos and Mesothelioma News - July 5, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: bap1 gene mutation doctor michele carbone gene therapy for mesothelioma mesothelioma clinical trial university of hawaii cancer center Source Type: news

Seattle Cancer Center Opens Latest Mesothelioma Clinical Trial
The Seattle Cancer Care Alliance has opened a phase II clinical trial involving durvalumab, the promising immunotherapy drug, in combination with chemotherapy for the first-line treatment of unresectable pleural mesothelioma. The U.S. Food and Drug Administration (FDA) already granted accelerated approval to durvalumab in May for the treatment of bladder cancer. Researchers have also lauded the drug for its effectiveness in earlier lung cancer clinical trials. “We have every reason to believe it will be effective with mesothelioma, too,” Dr. Bernardo Goulart, chief trial investigator and medical oncologist at t...
Source: Asbestos and Mesothelioma News - June 27, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: cancer in seattle doctor Bernardo Goulart mesothelioma clinical trials mesothelioma in seattle mesothelioma treatment seattle cancer care alliance Source Type: news

Time Between Surgeries Helps Predict Mesothelioma Survival
A new study from researchers at the City of Hope cancer center in Los Angeles and Wake Forest University School of Medicine in Winston-Salem, North Carolina, reveals how the length of time between initial and follow-up cytoreduction surgery and HIPEC plays a role in patient survival. The study, published in June in the Journal of Surgical Oncology, shows peritoneal mesothelioma patients who repeat the procedure between one and two years after the initial surgery have the most favorable outcome, with a median overall survival of nearly four years. Peritoneal mesothelioma is an aggressive, asbestos-related cancer, and recu...
Source: Asbestos and Mesothelioma News - June 23, 2017 Category: Environmental Health Authors: Matt Mauney Tags: appendiceal cancer city of hope cancer center colon cancer cytoreduction surgery debulking surgery Dr. Konstantinos Votanopoulos gastrointestinal cancer heated intraperitoneal chemotherapy HIPEC Journal of Surgical Oncology moffitt can Source Type: news

Can a Breath Test Diagnose Mesothelioma in the Early Stages?
Much of mesothelioma research centers on identifying new and noninvasive biomarkers for earlier detection of the asbestos-related cancer. Progress has been made in finding biomarkers in blood and pleural effusions, but researchers in Belgium now believe the next breakthrough in early diagnosis for mesothelioma cancer may be a breath test. Researchers at Ghent University Hospital and Antwerp University Hospital recently highlighted the potential of breath analysis, called breathomics, as a noninvasive screening tool for malignant pleural mesothelioma. The Oncotarget medical journal published the study in May. Breath tests...
Source: Asbestos and Mesothelioma News - June 20, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Antwerp University Hospital biomarkers breath tests biomarkers for mesothelioma biopsies mesothelioma breath analysis mesothelioma breath test mesothelioma breathomics chromatography-mass spectrometry early detection of mesothelioma elec Source Type: news

Mesothelioma Clinical Trial Opens with High Expectations
Newly diagnosed mesothelioma patients around the world have begun enrolling in a much-anticipated, phase III clinical trial involving an immunotherapy drug combination with groundbreaking potential. The trial, designed as first-line therapy for unresectable pleural mesothelioma, will measure the effectiveness of nivolumab (Opdivo) and ipilimumab (Yervoy) against standard-of-care chemotherapy. A presentation this month at the 2017 American Society of Clinical Oncology (ASCO) annual meeting sparked high expectations for the trial, detailing early, impressive effectiveness involving the two drugs in second-line and third-lin...
Source: Asbestos and Mesothelioma News - June 16, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Abramson Cancer Center American Society of Clinical Oncology Bristol-Myers Squibb cancer immunotherapy research cisplatin for mesothelioma Cleveland Clinic Cancer Center CRS-207 disease control rate Dr. Arnaud Scherpereel Dr. Patrick Ma Source Type: news

How Math Is Reshaping Mesothelioma Chemotherapy
This study demonstrates the feasibility of this approach since both preliminary encouraging signs of activity and no unexpected toxicities were observed, in this heavily pre-treated patients’ population.” Study Size and Rarity of Mesothelioma Present Challenges As a phase I clinical trial, it is a novel approach at this point but a promising step for future chemotherapy treatment plan protocols. The limited number of patients in the study — nine NSCLC and three mesothelioma — is also problematic, but the planned second phase of the study will include the new model’s effect on the immune syste...
Source: Asbestos and Mesothelioma News - June 13, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Aix-Marseille University anemia chemotherapy best vinorelbine regimen chemotherapy side effects Fabrice Barlesi low-dose oral chemotherapy drugs math cancer chemotherapy math to fight cancer mathematical modeling cancer mesothelioma chem Source Type: news

Chemotherapy Mix Doubles Peritoneal Mesothelioma Survival
Surgeon Paul Sugarbaker at the Washington Cancer Institute has nearly doubled the five-year survival rate for patients with peritoneal mesothelioma by adding long-term regional chemotherapy to his already groundbreaking protocol. Sugarbaker, a pioneer in advancing peritoneal mesothelioma treatment for more than two decades, believes this latest development could have far-reaching implications. “This could be a game changer,” Sugarbaker told Asbestos.com. “The reaction has been, ‘Wow! [It’s] hard to believe.’ We’ve got to exploit this [advancement] as best as we can.” Sugarbak...
Source: Asbestos and Mesothelioma News - June 7, 2017 Category: Environmental Health Authors: Matt Mauney Tags: cytoreductive surgery epithelioid cell type European Journal of Surgical Oncology HIPEC hyperthermic perioperative chemotherapy International Journal of Hyperthermia intraperitoneal chemotherapy long-term regional chemotherapy MedStar Wash Source Type: news

Using Viruses to Boost Mesothelioma Immunotherapy
Immunotherapy through clinical trials is becoming a promising treatment option for some mesothelioma patients. Checkpoint inhibitor drugs, such as Keytruda, already have U.S. Food and Drug Administration (FDA) approval as first-line treatments for non-small cell lung cancer (NSCLC), edging immunotherapy drugs closer to becoming a viable second-line therapy for other thoracic cancers, including pleural mesothelioma. However, overall response to immune therapies remains relatively low. Researchers across the country are striving to enhance responsiveness to immunotherapy drugs. Leading that trend is viroimmunotherapy, or t...
Source: Asbestos and Mesothelioma News - June 6, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Biomedicines checkpoint blockade Checkpoint inhibitor drugs clinical trials for mesothelioma Dr. Alexander Dash Dr. Manish Patel FDA approval Keytruda immune response cancer immunotherapy response mesothelioma intratumoral injections k Source Type: news

Methanol from African Plants Kills Mesothelioma Cells
This study provides evidences of the cytotoxicity of the tested plant extract and highlights the good activity of Elephantopus mollis and Kalanchoe crenata,” Kuete wrote. “They deserve more exploration to develop novel cytotoxic drugs.” The post Methanol from African Plants Kills Mesothelioma Cells appeared first on Mesothelioma Center - Vital Services for Cancer Patients & Families. (Source: Asbestos and Mesothelioma News)
Source: Asbestos and Mesothelioma News - June 2, 2017 Category: Environmental Health Authors: Matt Mauney Tags: African medicinal plants African whitewood apoptosis mesothelioma BMC Complementary and Alternative Medicine breast cancer Cameroon cancer chemotherapy colon cancer cytotoxicity against mesothelioma cells doxorubicin Dr. Victor Kuete Source Type: news

New Study Hopes to Improve Early Detection of Mesothelioma
Researchers in Germany have developed a novel blood test for mesothelioma cancer that could lead to earlier detection of the disease and a better prognosis for patients. The test involves calretinin, a blood-based protein that is overexpressed when mesothelioma tumors cells are present. The advancement stems from a study using a new enzyme-linked immunosorbent assay (ELISA) for detecting the biomarker more effectively. In the past, mesothelioma has been difficult to diagnose. It’s mostly accomplished with a combination of invasive tissue biopsies and detailed imaging tests after symptoms become obvious. A reliable bl...
Source: Asbestos and Mesothelioma News - May 30, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: biomarkers for mesothelioma calretinin assay epithelioid mesothelioma Georg Johnen Mesomark blood assay mesothelioma cancer research mesothelioma cancer treatment Source Type: news

New Bill Could Further Deregulate the Asbestos Industry
National environmental groups are banding together to fight the Regulatory Accountability Act, a bill they say would make it harder to protect consumers from dangerous substances such as asbestos. Officially known as the Regulatory Accountability Act (RAA) of 2017, it passed the U.S. House of Representatives in January and is now on the U.S. Senate floor. It combines six previously passed bills to eliminate what sponsors call “overly burdensome red tape and regulation,” while promising to hold federal agencies more accountable and create a more transparent rulemaking process. But critics claim the RAA has not...
Source: Asbestos and Mesothelioma News - May 25, 2017 Category: Environmental Health Authors: Matt Mauney Tags: asbestos ban Asbestos Ban and Phase-Out Rule asbestos legislation Corrosion Proof Fittings deregulation bills Donald Trump environmental protection agency Frank R. Lautenberg Chemical Safety for the 21st Century Act Natural Resources Defen Source Type: news

Mesothelioma Study Using Fitbit to Monitor Patient Recovery
Millions of Americans use Fitbit devices to track their daily activities, exercise and sleep patterns. But a student intern at the Pacific Heart, Lung & Blood Institute (PHLBI) in California is using the popular fitness tracker for a different purpose — as a tool to measure postsurgery recovery for mesothelioma patients. Blair Kimble, a third-year undergraduate student at UCLA, is leading the latest clinical research project for the Pacific Mesothelioma Center (PCM), a division of PHLBI. Kimble is working closely with mesothelioma surgeon Dr. Robert Cameron, the scientific advisor at PHLBI. The study investigat...
Source: Asbestos and Mesothelioma News - May 23, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Blair Kimble cancer immunotherapy research cryotherapy Dr. Raymond Wong Dr. Robert Cameron Dr. Steven Ching extrapleural pneumonectomy fitbit fitbit cancer recovery heated intraperitoneal chemotherapy Loyola Marymount University meso Source Type: news

Genetic Biomarkers Key to Future Mesothelioma Treatment
Researchers in Slovenia have developed a unique, treatment-recommendation model for mesothelioma patients based heavily upon individualized, genetic biomarkers. They believe their model will lead to better patient outcomes and significantly improve the response rate to chemotherapy, which is still less than 40 percent with mesothelioma. “This is just a start, but it’s going to be the way to go in the future, personalizing treatment,” Dr. Vita Dolzan, founder of Pharmacogenetics Laboratory at the University of Ljubljana’s Institute of Biochemistry, told Asbestos.com. “We’re excited about ...
Source: Asbestos and Mesothelioma News - May 22, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Anhovo Asbestos Valley Slovenia chemotherapy drugs for mesothelioma cisplatin CRP protein Dr. Vita Dolzan gemcitabine genetic biomarkers genetic makeup mesothelioma patients Genotyping mesothelioma treatment strategies pemetrexed p Source Type: news

Latest Keytruda Approval Promising for Mesothelioma Patients
The U.S. Food and Drug Administration (FDA) expanded its approval of pembrolizumab for first-line treatment of metastatic non-small cell lung cancer last week, moving it closer to becoming a viable treatment option for patients with pleural mesothelioma. Pembrolizumab is marketed by Merck & Co. under the brand name Keytruda. It helps the body’s immune system detect and destroy cancer cells. The FDA approved its first-line use in combination with pemetrexed and carboplatin, two chemotherapy agents used regularly for mesothelioma. Pembrolizumab, the most well-known immunotherapy drug, is being studied for use with...
Source: Asbestos and Mesothelioma News - May 19, 2017 Category: Environmental Health Authors: Matt Mauney Tags: carboplatin chemotherapy for mesothelioma Dr. Raymond Wong Dr. Tawee Tanvetyanon FDA approval Keytruda first line treatment for mesothelioma Hodgkin lymphoma jimmy carter keytruda clinical trial keytruda for mesothelioma melanoma Mer Source Type: news

Asbestos Blocked for 6th Time from Hazardous Substances List
The fight to impose tough trade restrictions on chrysotile asbestos — a toxic mineral that causes mesothelioma cancer and other serious health conditions — will have to wait at least another two years. For the sixth consecutive time, a handful of countries blocked the inclusion of the carcinogenic mineral from the Rotterdam Convention Hazardous Substances list (Annex III). Chemicals on the list are subject to restrictions that prevent the export of a product without the consent of the importing country. Representatives from 157 countries met in Geneva, Switzerland, for the eighth Conference of the Parties (CO...
Source: Asbestos and Mesothelioma News - May 17, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Andrew Dettmer Annex III asbestos ban in canada asbestos ban in united states Asbestos Disease Awareness Organization asbestos export regulations Australian Manufacturing Workers Union Belarus Chrysotile asbestos fibers Conference of the Source Type: news

Study Links Mesothelioma in Women to Cloth Dolls in Factory
A rising number of women are diagnosed with mesothelioma cancer each year. Researchers in Italy are the latest to study this growing trend and show that asbestos exposure — the main cause of mesothelioma — doesn’t only affect men working certain blue-collar jobs. The report, published in the Italian medical journal La Medicina del Lavoro in April, analyzes possible asbestos exposure in a cloth doll factory. Using data from the Province of Brescia Mesothelioma Registry, researchers found three cases of pleural mesothelioma cancer diagnosed in young women who had worked for two doll manufacturing companies....
Source: Asbestos and Mesothelioma News - May 16, 2017 Category: Environmental Health Authors: Matt Mauney Tags: asbestos cloth doll factory asbestos doll manufacturing environmental asbestos exposure La Medicina del Lavoro mesothelioma cloth doll workers mesothelioma in Italy occupational asbestos exposure Pietrogino Barbieri Province of Brescia Mes Source Type: news

Multiple Sclerosis Drug Effectively Stops Mesothelioma Cells
Research from the University of Hawaii Cancer Center shows an immune suppression drug already used to treat multiple sclerosis could become an effective tool against malignant mesothelioma. The drug, fingolimod (FTY720), showed an ability to shrink mesothelioma tumors cells in the laboratory and in animal models without causing substantial side effects. Fingolimod, which is derived from the fungus isaria sinclairii, also is being studied for potential use with cervical, breast, lung and prostate cancers. This was the first study of its effectiveness with mesothelioma. The Journal of Translational Medicine published the res...
Source: Asbestos and Mesothelioma News - May 11, 2017 Category: Environmental Health Authors: Matt Mauney Tags: anti-cancer effect on mesothelioma cells Dr. Haining Yang fingolimod mesothelioma FTY720 immune suppression drugs isaria sinclairii Journal of Translational Medicine mesothelioma life expectancy multiple sclerosis drugs Repurposing drugs Source Type: news

New VA Health Care Bill Can Help Mesothelioma Patients
A recent extension and reform of the Veterans Choice Program could allow for better access to care for veterans diagnosed with rare cancers such as mesothelioma. President Donald Trump signed the Veterans Choice Program Extension and Improvement Act (S.544) into law on April 18. The bill amends the Veterans Access, Choice, and Accountability Act of 2014, eliminating the Aug. 7, 2017, expiration date and allowing the program to operate until the remaining $950 million in the Veterans Choice Fund is expended. Under the new law, military veterans can continue receiving health care in the private sector when care isn’...
Source: Asbestos and Mesothelioma News - May 10, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Aaron Munz David Shuklin Donald Trump mesothelioma life expectancy military veterans asbestos exposure pending VA claims President Barack Obama private health care for veterans Trump executive orders VA accountability and whistleblower p Source Type: news

FDA Cracks Down on Fake Mesothelioma Treatments
Stories abound of a “cancer-curing” tea from the forests of Canada. Herbal blends claim to “attack cancer at the DNA level.” For many years, mesothelioma patients have turned to alternative medicines like these as treatment options for the rare asbestos-related cancer. Sometimes these options are a last resort, after traditional treatments fail. They may be used in conjunction with standard treatment (complementary medicine) or on their own as the main approach. But the U.S. Food and Drug Administration (FDA) recently issued warning letters to companies that manufacture or market products claimin...
Source: Asbestos and Mesothelioma News - May 2, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Alternative medicine Asparagus Extract BioStar Technology International Budwig Protocol cancer supplements cannabis oil cancer CellAssure Centers for Disease Control and Prevention Chelated Boron Circulatory Detox & Support Syrup compl Source Type: news

New Mesothelioma Clinical Trial for Pleural, Peritoneal Patients
Pleural and peritoneal mesothelioma patients are eligible for a new clinical trial that combines the latest antibody-drug conjugate with standard-of-care chemotherapy at the Ochsner Medical Center in New Orleans. The drug, anetumab ravtansine (BAY 94-9343), is the highly touted conjugate that mixes immunotherapy with cytotoxic therapy and targets mesothelin, the tumor surface protein found in 85-90 percent of mesothelioma cancer patients. The Ochsner trial, which is currently recruiting participants, is the first time researchers will administer anetumab ravtansine in a first-line setting for mesothelioma. “It’...
Source: Asbestos and Mesothelioma News - April 28, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: anetumab ravtansine mesothelioma chemotherapy mesothelioma clinical trial new mesothelioma treatment ochsner clinical trial Source Type: news

Moffitt Opens Mesothelioma Study for Rare Cancer Subtypes
The Moffitt Cancer Center in Tampa has opened a mesothelioma clinical trial involving an anti-cancer enzyme drug showing unprecedented success with the most difficult disease subtypes. Patients with sarcomatoid and biphasic histology — the most treatment-resistant subtypes of mesothelioma — can now enroll in a phase 2/3 clinical trial involving the effectiveness of ADI-PEG 20 (pegylated arginine deiminase) in combination with standard chemotherapy. Thoracic surgeon Dr. Jacques Fontaine, director of the Mesothelioma Research and Treatment Center at Moffitt, told Asbestos.com that he and fellow investigators are ...
Source: Asbestos and Mesothelioma News - April 25, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: doctor jacques fontaine improving mesothelioma prognosis mesothelioma chemotherapy with cisplatin mesothelioma clinical trial mesothelioma treatments moffitt cancer center Source Type: news

Select Mesothelioma Patients Still Benefit from EPP Surgery
The controversial extrapleural pneumonectomy (EPP) surgery should remain a viable option for select patients with malignant mesothelioma, despite a growing reluctance today among thoracic surgeons to recommend the procedure. When combined with intensity modulated radiation therapy (IMRT), the EPP still can benefit some patients and improve survival times significantly, according to a recent study at the Baylor Scott & White Medical Center in Temple, Texas. The retrospective look at 18 patients who underwent the EPP/IMRT combination found an average, overall survival rate of 38.2 months and a median relapse-free surviva...
Source: Asbestos and Mesothelioma News - April 17, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: extrapleural pneumonectomy intensity modulated radiation therapy mesothelioma life expectancy mesothelioma surgery mesothelioma survival rates Source Type: news

Asbestos Contaminates Canadian University Labs
Fear and frustration best describes emotions felt by University of Toronto faculty and students after they say administration delayed notification that asbestos contaminated some of the university’s science labs. “The emotional experience is really devastating,” said physiology and medicine professor Adria Giacca in an interview with CBC News. Another professor, who didn’t want to be identified, told the Globe and Mail: “I’ve lost confidence, and my lab people have lost confidence…[It] perpetuates fear whenever you see dust, you now worry. Am I going to get cancer 20 years from no...
Source: Asbestos and Mesothelioma News - April 12, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: asbestos ban in canada asbestos exposure in canada asbestos exposure in schools asbestos in canada Source Type: news

Shorter Mesothelioma Survival Linked to High Platelet Count
A disorder that forces the body to overproduce platelets is now linked to worsening the prognosis of peritoneal mesothelioma patients, according to researchers at the University of Maryland School of Medicine. Previous clinical trials associated a high platelet count, also known as thrombocytosis, with poor outcomes for various malignancies. However, the recent study at The Greenebaum Comprehensive Cancer Center in Baltimore is the first to evaluate the clinical significance of thrombocytosis with mesothelioma cancer. The study, published March 21 in the Annals of Surgical Oncology, analyzed overall survival for peritoneal...
Source: Asbestos and Mesothelioma News - April 3, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: chemotherapy for mesothelioma heated intraperitoneal chemotherapy hyperthermic intraperitoneal chemotherapy mesothelioma survival peritoneal mesothelioma survival platelet count for mesothelioma thrombocytosis for mesothelioma Source Type: news

Keytruda Proves Effectiveness with Mesothelioma
This study provides evidence that some patients [with mesothelioma] can have long-term disease control with this drug, which we haven’t seen before,” Alley said in a press release. “This drug appears to be well tolerated.” Real Need for Second-Line Therapy Standard first-line therapy for mesothelioma includes a combination of chemotherapy, radiation and surgery, but it remains relatively ineffective as a long-term solution. Alley believes pembrolizumab, classified as a checkpoint inhibitor drug, can provide a needed advancement in treatment. Checkpoint inhibitors allow the immune system to fight off...
Source: Asbestos and Mesothelioma News - March 31, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Abramson Cancer Center checkpoint inhibitors Dr. Evan Alley keytruda keytruda clinical trials keytruda for mesothelioma Merck & Co. PD-L1 proteins pembrolizumab Pembrolizumab mesothelioma Penn Medicine Penn Presbyterian Medical Cente Source Type: news

Nutritional Index Helps Predict Mesothelioma Prognosis
A recent study further expands on the important role nutrition plays in how well mesothelioma patients will respond to treatments. Researchers in Japan evaluated the Controlling Nutritional Status (CONUT) score — an index developed as a screening tool for early detection of poor nutritional status — as a predictive marker for mesothelioma prognosis. CONUT has been used to predict the prognosis of other cancers, but never for malignant pleural mesothelioma (MPM), a rare and aggressive cancer caused by exposure to asbestos. “The CONUT score was an independent predictor of a poor prognosis in the patients...
Source: Asbestos and Mesothelioma News - March 29, 2017 Category: Environmental Health Authors: Matt Mauney Tags: bap1 gene mutation Controlling Nutritional Status score CONUT score malignant pleural mesothelioma mesothelioma malnutrition mesothelioma nutrition Mesothelioma prognosis mesothelioma stages nutrition mesothelioma survival Osaka City Uni Source Type: news

Mesothelioma Researcher Questions Benefits of EPP Surgery
Former thoracic surgeon Dr. Tom Treasure at University College London was never a believer in the aggressive extrapleural pneumonectomy (EPP) surgery still performed today for patients with malignant pleural mesothelioma. As a researcher now, he dismisses the potential benefit with even more conviction. “Doing the EPP can’t be justified anymore,” Treasure told Asbestos.com. “One more [of these surgeries] is one too many. I feel more confident about that now than ever before. We really have to spare people from the treatments that don’t help.” In recent years, the mesothelioma community h...
Source: Asbestos and Mesothelioma News - March 27, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: doctor david sugarbaker Doctor Tom Treasure EPP surgery for mesothelioma lung institute at baylor mesothelioma surgery mesothelioma treatment pleurectomy decortication Source Type: news

Veterans with Mesothelioma Benefit from Telephone Triage
U.S. military veterans with malignant pleural mesothelioma can rely on the VA Boston Healthcare System’s national phone triage for improved access to specialized surgical advice and better treatment recommendations, according to a retrospective study. Thoracic surgeons Drs. Abraham Lebenthal and Jeff Siegert helped establish the open access telephone triage in 2011, shortening the average time between a veteran’s initial phone screen and face-to-face surgical consultation to 14 days. Many veterans facing a potential diagnosis of mesothelioma must navigate the historically mismanaged federal agency to get the tr...
Source: Asbestos and Mesothelioma News - March 20, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Boston VA Brigham and Women’s Hospital Dr. Abraham Lebenthal Dr. Jeff Siegert malignant pleural mesothelioma military veterans mesothelioma Telephone triage VA benefits Source Type: news

Trump Will Likely Support Asbestos FACT Act
A House Judiciary Committee approved the Furthering Claims Transparency Act of 2017, one of numerous iterations of the legislation since 2004, which asbestos foes claim will hurt those seeking much-deserved compensation. Repeatedly stalled in the legislature in previous years with a promised veto from President Barack Obama, supporters are hopeful President Donald Trump will support the bill as part of a reform package. Republican sponsor U.S. Rep. Blake Farenthold of Texas introduced the bill in February. Opponents Fear Asbestos Victims’ Privacy Is at Stake Linda Reinstein, president of the Asbestos Disease Awarenes...
Source: Asbestos and Mesothelioma News - March 7, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: Asbestos Disease Awareness Organization asbestos trust claims asbestos trusts FACT Act filing an asbestos trust claim Furthering Claims Transparency Act of 2017 Linda Reinstein trump asbestos U.S. Rep. Blake Farenthold Source Type: news

Hospice Program Eases Breathing for Mesothelioma Patients
Dr. Michael Shapiro has developed a program that should make breathing easier for a patient with malignant pleural mesothelioma. He equates his breathing program to teaching an elite athlete how to better utilize his lung capacity by using similar concepts that assist people struggling with serious respiratory issues in hospice care. “We’re not reinventing the wheel, by any stretch of the imagination,” Shapiro told Asbestos.com. “But there are ways to teach people, at all levels, to breath more efficiently. Our goal is to help provide a better quality of life for a patient.” Shapiro is the chi...
Source: Asbestos and Mesothelioma News - March 3, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: breathing exercises for mesothelioma dr. michael shapiro hospice care for mesothelioma mesothelioma treatment Source Type: news

Firefighters with Mesothelioma Protected by New Ohio Law
A new piece of legislation extends workers’ compensation rights for Ohio firefighters to include occupational cancers such as mesothelioma. Ohio Gov. John Kasich signed the Michael Louis Palumbo Jr. Act into law Jan. 4. The bill essentially classifies cancer as an occupational disease for firefighters, allowing firefighters who have cancer to file claims with the Ohio Bureau of Workers’ Compensation. More than 30 states already have similar laws. Doug Stern of the Ohio Association of Professional Firefighters (OAPFF) said the legislation is based on scientific research that links asbestos-related cancers, suc...
Source: Asbestos and Mesothelioma News - January 30, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: firefighters asbestos exposure firefighters with mesothelioma governor john kasich occupational mesothelioma cancer ohio law protects firefighters Source Type: news

$80M Asbestos Settlement Reached in Kansas City
An $80 million asbestos settlement involving two former Jackson County courthouse employees led to Missouri’s largest medical monitoring fund established in an asbestos case. The class-action asbestos lawsuit settled more than 30 years after a renovation exposed thousands of government workers to deadly asbestos fibers. Jackson County and Kansas City-based U.S. Engineering, the firm responsible for the asbestos removal, agreed to settle the case in October 2016, just a week prior to the opening trial date. An estimated 7,500 people — former courthouse employees, jurors, attorneys and jail inmates — could...
Source: Asbestos and Mesothelioma News - January 25, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: asbestos in kansas city courthouse asbestos lawsuit asbestos litigation in missouri asbestos settlement kansas city asbestos lawsuit kansas city asbestos settlement mesothelioma lawsuit mesothelioma lawyer in missouri Source Type: news

Study Finds Unique Mesothelioma Incidence Rates in China
A study analyzing mesothelioma incidence rates in Eastern China produced unusual findings, contrasting significantly from statistics of the asbestos-related cancer in the U.S. Reported incidence rates in China are significantly lower than the U.S. Only 15 percent of cases examined in the study were linked to asbestos exposure, the overwhelming cause of mesothelioma in most countries around the world. China’s results are contradictory for a country which remains one of the world’s largest producers and users of the carcinogenic mineral. Other contrasting findings from the study: Peritoneal mesothelioma cas...
Source: Asbestos and Mesothelioma News - January 23, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: asbestos exposure in china asbestos use in china mesothelioma in china nonasbestos mesothelioma peritoneal mesothelioma in china Source Type: news

EPA: ‘ Last Call ’ for Asbestos Cleanup in Libby, Montana
The U.S. Environmental Protection Agency (EPA) has made a “last call” at the Libby Asbestos Superfund site, giving residential and commercial property owners one final chance to benefit from its asbestos cleanup efforts. Property owners in Libby and nearby Troy, Montana, will have until March 31 to sign up, bringing closure to the largest, longest-running asbestos cleanup project in American history. “This last call really signals the end of the project, which has been a bit of a dark cloud hanging over our area for some time,” Nick Raines, manager of the Lincoln County Asbestos Resources Program, t...
Source: Asbestos and Mesothelioma News - January 18, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: asbestos cleanup in libby montana asbestos exposure in montana asbestos in libby asbestos regulations asbestos removal in libby montana asbestos superfund site in libby asbestos superfund sites epa asbestos cleanup Source Type: news

Mesothelioma Vaccine Aims to Stop Cancer Before It Begins
Dr. Pietro Bertino can envision a time when mesothelioma cancer no longer exists. He can see it through the work he does every day. Bertino is an assistant researcher in the Cell and Molecular Biology Department at the John A. Burns School of Medicine at the University of Hawaii. The U.S. Department of Defense awarded Bertino a three-year, $550,000 research grant to advance the development of a multiantigen mesothelioma vaccine aimed at prevention and therapeutics. His early work shows significant promise. “We are making progress. You can already see it,” Bertino told Asbestos.com. “It’s going to ...
Source: Asbestos and Mesothelioma News - January 17, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: bap1 gene mutation john a burns school of medicine mesothelioma grants mesothelioma research grant mesothelioma vaccine pietro bertino university of hawaii cancer center Source Type: news

Heating Tumors May Improve Mesothelioma Treatments
A recent study shows heating malignant tumors could improve treatments for mesothelioma and other cancers. Researchers in France successfully softened malignant tumors by heating them, a process known as nanohyperthermia, which altered the collagen fibers and reduced the rigidity and volume of the tumors, making them more susceptible to chemotherapy and other therapeutic treatments. Malignant tumors, such as those found in mesothelioma patients, demonstrate a mechanical resistance to standard treatments, hindering efforts to defeat cancers. Stiffening is a characteristic of cancer cells, and one that may help the cells p...
Source: Asbestos and Mesothelioma News - January 13, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: heating cancer tumors mesothelioma treatments new mesothelioma treatments treating cancer with carbon nanotubes treating peritoneal mesothelioma treating pleural mesothelioma Source Type: news

Mesothelioma Patients Benefit from Integrative Medicine Expert
Dr. Ka-Kit Hui is no expert on mesothelioma cancer, but he helps mesothelioma patients live longer and better lives every day. Committed to teaching the benefits of integrative medicine, Hui’s vision blends the best of traditional Chinese and conventional Western medicines, skillfully bridging the gap between the two. He launched the UCLA Center for East-West Medicine in 1993 — one of the first integrative medicine centers in the U.S. — leading it to national prominence. Clinically proven to improve health and healing, its programs often increase survival time. “Our hope is to do things that impro...
Source: Asbestos and Mesothelioma News - January 12, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: doctor ka-kit hui at ucla east west medicine integrative medicine for mesothelioma international symposium on malignant mesothelioma mesothelioma research Source Type: news

Early Detection of Mesothelioma Lies in HMGB1 Isoforms
An international research team is exploring how variants of an important blood protein could be the key to prevention and early detection of malignant mesothelioma. Dr. Haining Yang at the University of Hawaii Cancer Center is leading the research and recently presented potential strategies at the 6th International Symposium on Malignant Pleural Mesothelioma. Previously, Yang and her team showed how the High-Mobility Group Box 1 (HMGB1) protein sparks the proliferation and survival of cancerous mesothelioma cells. Yang and colleagues recently discovered that isoforms or “protein variants” of HMGB1 could be a ...
Source: Asbestos and Mesothelioma News - January 9, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: early detection of mesothelioma early diagnosis of mesothelioma early mesothelioma diagnosis hmgb1 isoforms malignant pleural mesothelioma mesothelioma research mesothelioma survival Source Type: news

Canada Will Ban Asbestos by 2018
After the latest push from unions and federal labor advocates, the Canadian government is moving to ban asbestos by 2018. Science Minister Kirsty Duncan announced the long-awaited news in late December. The ban will apply to the manufacture of any products containing asbestos, as well as imports made with the deadly mineral. It could be extended to products already manufactured. New Democrat Party Critic for Labour Sheri Benson introduced Bill C-321 in November to help speed the process. Despite a steep decline in global demand and Canada’s last asbestos mines closing in 2012, the Canadian government continued to dr...
Source: Asbestos and Mesothelioma News - January 4, 2017 Category: Environmental Health Authors: Walter Pacheco Tags: asbestos ban asbestos ban in canada asbestos deaths in canada asbestos in canada justin trudeau asbestos ban mesothelioma in canada Source Type: news

Sugarbaker Touts New Clinical Study for Mesothelioma Patients
This study expands on what we already know about surgery and chemotherapy for mesothelioma, and combines them in a new way…with the goal of reducing recurrence rates and improving survival and quality of life,” Groth said in a press release from the Baylor Medical Center. “The heated chemotherapy fluid is effective at killing cancer and making the chemotherapy work better.” Baylor also has other ongoing mesothelioma clinical trials: A phase II study of anetumab ravtansine for patients with unresectable pleural mesothelioma and high expression of mesothelin, a vulnerable, tumor-surface protein link...
Source: Asbestos and Mesothelioma News - December 22, 2016 Category: Environmental Health Authors: Walter Pacheco Tags: baylor college of medicine chemotherapy for mesothelioma dr. david sugarbaker mesothelioma chemotherapy drugs mesothelioma clinical trial mesothelioma treatment center at baylor Source Type: news

Mesothelioma Trial for Nintedanib Shows Positive Results
Researchers have reported more promising results from an international, multicenter phase II clinical trial of the drug nintedanib, moving it another step closer to standard-of-care treatment for pleural mesothelioma. Nintedanib is a small-molecule enzyme inhibitor being studied as a way to increase the effectiveness of chemotherapy on mesothelioma and certain types of lung cancer. Researchers presented the results earlier this month at the World Conference on Lung Cancer in Vienna, Austria. The randomized clinical trial treated mesothelioma patients with a placebo and chemotherapy (pemetrexed/cisplatin) or nintedanib and ...
Source: Asbestos and Mesothelioma News - December 22, 2016 Category: Environmental Health Authors: Walter Pacheco Tags: chemotherapy clinical trial chemotherapy for mesothelioma extending mesothelioma survival mesothelioma treatment nintedanib Source Type: news

Study Shows Impact of Chemotherapy on Mesothelioma
A U.S.-based study confirms what oncology experts have suggested for years — chemotherapy treatment prolongs life expectancy for malignant mesothelioma patients. Wayne State University School of Medicine researchers linked data from the National Cancer Institute’s Surveillance, Epidemiology and End Results (SEER) database with Medicare claims data. The study took into account patient characteristics such as age, gender and amount of asbestos exposure. Not only did the findings show mesothelioma patients who have chemotherapy live longer, but it also proved multimodal therapy increases survival even more. The s...
Source: Asbestos and Mesothelioma News - December 19, 2016 Category: Environmental Health Authors: Walter Pacheco Tags: chemotherapy clinical trial chemotherapy for mesothelioma doctor shirish gadgeel first line treatment for mesothelioma Human Investigation Committee at Wayne State mesothelioma diagnosis peritoneal mesothelioma wayne state university Source Type: news

Pearl Harbor: 75th Anniversary & Future Asbestos Dangers for Veterans
Seventy-five years later, Dec. 7, 1941, still lives in infamy. Wednesday marks the 75th anniversary of the attack on Pearl Harbor. The surprise Japanese military strike killed 2,403 Americans and wounded another 1,178, devastating the U.S. naval base and dragging the nation into World War II. But the death toll continued to rise decades after the attack because more than 10,000 veterans who served in Pearl Harbor were exposed to deadly asbestos released at the shipyards on the day of the attack. As we remember the lives lost in the attack and honor the survivors still with us today on Pearl Harbor Day, it is important to ...
Source: Asbestos and Mesothelioma News - December 6, 2016 Category: Environmental Health Authors: Walter Pacheco Tags: 75 years after pearl harbor pearl harbor 75th anniversary pearl harbor attack pearl harbor attack anniversary veterans exposed to asbestos Source Type: news

Cryoablation Successfully Treats Recurrent Mesothelioma
Radiologists at the UCLA Medical Center are successfully killing tumor cells with extreme cold, also known as cryoablation, in patients with recurrent pleural mesothelioma. An outpatient procedure with few complications, cryoablation freezes the localized tumors with argon gas or liquid nitrogen, allowing patients to fight the almost-inevitable cancer recurrence after surgery. Dr. Fereidoun Abtin, a UCLA radiologist who performs the procedure, told Asbestos.com he is “convinced it works well for these patients.” “The results have been impressive, a lot better than what else is out there in the literature ...
Source: Asbestos and Mesothelioma News - December 6, 2016 Category: Environmental Health Authors: Walter Pacheco Tags: cryoablation for cancer cryoablation for mesothelioma cryosurgery for mesothelioma cryotherapy for mesothelioma freezing cancer tumors mesothelioma treatment Source Type: news

Extending Late-Stage Mesothelioma Survival with Light Energy
Thoracic surgeon Dr. Joseph Friedberg and his colleagues identified a subset of patients with pleural mesothelioma who achieved a median overall survival of 7.3 years — an impressive survival compared to the usual one-year prognosis. The findings, which were published recently in The Annals of Thoracic Surgery, stemmed from a retrospective study that detailed significant progress in the fight against this incurable, asbestos-related cancer. The study included 73 patients with epithelioid mesothelioma who were treated at the Penn Medicine Abramson Cancer Center, where Friedberg practiced before taking the role of dire...
Source: Asbestos and Mesothelioma News - December 1, 2016 Category: Environmental Health Authors: Walter Pacheco Tags: doctor joseph friedberg late stage mesothelioma stage 3 mesothelioma stage 4 mesothelioma stage III mesothelioma stage IV mesothelioma treatment for late stage mesothelioma treatment for pleural mesothelioma Source Type: news