PhD warns that at least 150,000 Americans have died from covid vaccines (so far)
(Natural News) Based on data collected from the VAERS (Vaccine Adverse Event Reporting System) database, Dr. Jessica Rose, PhD, a computational biologist, molecular biologist and immunologist, has determined that at least 150,000 people in the United States have died from Wuhan coronavirus (Covid-19) “vaccines” as of Aug. 28, 2021. Rose utilized both VAERS data and... (Source: NaturalNews.com)
Source: NaturalNews.com - October 11, 2021 Category: Consumer Health News Source Type: news

$6.2 million NIH grant to support UCLA study of how COVID-19 causes multiple organ failure
Researchers from the  Eli and Edythe Broad Center of  Regenerative Medicine and Stem Cell Research at UCLA have received a $6.2 million grant from the National Institutes of Health to study how the SARS-CoV-2 virus causes damage throughout the body.The Director ’s Transformative Research Award was presented through the NIH’s prestigious High Risk, High Reward program, which supports creative and unconventional approaches to major challenges in biomedical and behavioral research. What makes SARS-CoV-2, the virus that causes COVID-19, so dangerous for some people is that although it is a respi...
Source: UCLA Newsroom: Health Sciences - October 5, 2021 Category: Universities & Medical Training Source Type: news

Oxford Covid biotech firm makes stellar debut on London stock market
Shares of Oxford Nanopore close up 44%, giving co-founder paper fortune of £63mSee all our coronavirus coverageOxford Nanopore, whose DNA sequencing technology has been essential in tracking Covid-19 variants globally, has made a stellar stock market debut in London. A rise in its share price of as much as 47% has left the firm valued at almost £5bn.The flotation of the Oxford University spin-out has given its chief executive and co-founder, Gordon Sanghera, a fortune on paper of £63m.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - September 30, 2021 Category: Science Authors: Julia Kollewe Tags: IPOs FTSE Stock markets Nanotechnology Biochemistry and molecular biology Science University of Oxford Business UK news Source Type: news

Bristol retains Strategic Partnership with the BBSRC and ranks fourth for bioscience research funding  
The   BBSRC, one of the UK ’ s largest UK bioscience funders, has announced Bristol will retain its Strategic Partnership (SP) status. The decision was announced this month following   BBSRC ’ s SP member triannual review. Bristol is one of only ten top-funded university   partners with this status – which it has retained since 2012 recognising the University ’ s long-term record for excellence in biosciences research.   (Source: University of Bristol news)
Source: University of Bristol news - September 30, 2021 Category: Universities & Medical Training Tags: Grants and Awards, Business and Enterprise, Research; Faculty of Life Sciences, Faculty of Life Sciences, School of Biological Sciences, Faculty of Life Sciences, School of Biochemistry, Faculty of Life Sciences, School of Cellular and Molecular Medicine, Source Type: news

Antibodies in breast milk remain for 10 months after Covid infection – study
Exclusive: Researchers believe such antibodies could be used to treat people with severe coronavirusCoronavirus – latest updatesSee all our coronavirus coverageBreastfeeding women who have been infected with Covid-19 continue to secrete virus-neutralising antibodies into their milk for up to 10 months, data suggests.Besides emphasising the important role breastfeeding could play in helping to protect infants from the disease, researchers believe that such antibodies could be used to treat people with severe Covid-19, preventing their condition from getting worse.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - September 27, 2021 Category: Science Authors: Linda Geddes Tags: Breastfeeding Coronavirus Science Infectious diseases Microbiology Immunology World news Medical research Biochemistry and molecular biology Source Type: news

UCLA Broad Stem Cell Research Center receives $5 million CIRM grant for research training program
TheEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLAhas been awarded $5 million by the California Institute for Regenerative Medicine, the state ’s stem cell agency, to train young scientists and physicians to become leaders in the stem cell and regenerative medicine field.The five-year grant will enable the center to expand its Stem Cell Training Program, which was established in 2006 and funded by CIRM until 2015, when the agency changed its funding priorities. Since then, the program has been sustained by philanthropy. With the passage of Proposition 14 last fall, however, CIRM ha...
Source: UCLA Newsroom: Health Sciences - September 23, 2021 Category: Universities & Medical Training Source Type: news

Graduate Student in Cancer Research is First at Dartmouth to Receive Prestigious NCI Award
Jichang Han, BS, is the first at Dartmouth to receive a Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) from the National Cancer Institute (NCI) of the National Institutes of Health (NIH). (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - September 22, 2021 Category: Hospital Management Authors: NonPerson Geisel Web Service Acct Tags: Education News Molecular and Cell Biology Norris Cotton Cancer Center Source Type: news

Rapping molecular scientist offers Nicki Minaj a lesson about COVID vaccines
Dr. Raven “the Science Maven” Baxter, an award-winning science educator, molecular biologist and lyricist, offered rapper Nicki Minaj an... (Source: Reuters: Health)
Source: Reuters: Health - September 17, 2021 Category: Consumer Health News Source Type: news

Exploration of < em > In-silico < /em > Screening of Therapeutic Agents Against SARS-CoV-2
Chem Phys. 2021 Sep 4:111354. doi: 10.1016/j.chemphys.2021.111354. Online ahead of print.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the at...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > Screening of Therapeutic Agents Against SARS-CoV-2
Chem Phys. 2021 Sep 4;551:111354. doi: 10.1016/j.chemphys.2021.111354. Online ahead of print.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for th...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > Screening of Therapeutic Agents Against SARS-CoV-2
Chem Phys. 2021 Sep 4;551:111354. doi: 10.1016/j.chemphys.2021.111354. Online ahead of print.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for th...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > Screening of Therapeutic Agents Against SARS-CoV-2
Chem Phys. 2021 Sep 4;551:111354. doi: 10.1016/j.chemphys.2021.111354. Online ahead of print.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for th...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > Screening of Therapeutic Agents Against SARS-CoV-2
Chem Phys. 2021 Sep 4;551:111354. doi: 10.1016/j.chemphys.2021.111354. Online ahead of print.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for th...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Exploration of < em > In-silico < /em > screening of therapeutic agents against SARS-CoV-2
Chem Phys. 2021 Nov 1;551:111354. doi: 10.1016/j.chemphys.2021.111354. Epub 2021 Sep 4.ABSTRACTIn the present investigation, molecular docking studies have been performed using AutoDock Vina to investigate the role of ligand-binding affinity at the hydrophobic pocket of COVID-19. The knowledge of the binding of protein receptors with ligand molecules is essential in drug discovery processes. Hydroxamic acids with reported biological activity, have been investigated for docking to an important target, SARS-CoV-2, in order to predict their therapeutic efficacy. The spike protein of the coronavirus is responsible for the atta...
Source: Chemical Physics - September 13, 2021 Category: Chemistry Authors: Yamini Thakur Rama Pande Source Type: news

Oxford Covid biotech firm plans £2.4bn flotation on LSE
Business founded in 2005 has won contracts worth £144m from the UK government during pandemicOxford Nanopore, whose Covid-19 technology wassnapped up by the UK government and used to track variants of the virus globally, has unveiled its plans to float in one of the biggest London debuts this year.The company, a startup spun out from Oxford University, hopes to exceed a £2.4bn valuation achieved at a fundraising round in May. It has laid out plans to tap into the growing genomic sequencing market, estimated to be worth $5.7bn globally. Its revenues more than doubled to £114m last year, from £52m in ...
Source: Guardian Unlimited Science - September 9, 2021 Category: Science Authors: Julia Kollewe Tags: IPOs Biochemistry and molecular biology Coronavirus Nanotechnology University of Oxford Business Stock markets Science Infectious diseases Source Type: news

UK scientists win £2.2m Breakthrough prize for DNA reading advances
Creators of next-generation genome sequencing take science ’s most lucrative awardTwo British researchers have won the most lucrative prize in science for work that dramatically improved the speed and reduced the cost of reading DNA, the molecular instructions for life.Sir Shankar Balasubramanian and Sir David Klenerman, both professors at the University of Cambridge, share the $3m ( £2.2m) Breakthrough prize in life sciences with Pascal Mayer, the founder of the French firm Alphanosos, for creating next-generation genome sequencing, or NGS.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - September 9, 2021 Category: Science Authors: Ian Sample Science editor Tags: Science Genetics Vaccines and immunisation Coronavirus UK news Biology Health Society Infectious diseases Source Type: news

AI algorithm solves structural biology challenges
Determining the 3D shapes of biological molecules is one of the hardest problems in modern biology and medical discovery. Companies and research institutions often spend millions of dollars to determine a molecular structure - and even such massive efforts are frequently unsuccessful. (Source: World Pharma News)
Source: World Pharma News - August 26, 2021 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

[Ad hoc announcement pursuant to Art. 53 LR] Phase III study shows Roche's Polivy plus R-CHP is the first regimen in 20 years to significantly improve outcomes in previously untreated aggressive form of lymphoma compared to standard of care
Basel, 9 August 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the pivotal phase III POLARIX trial investigating Polivy ® (polatuzumab vedotin) in combination with MabThera®/Rituxan® (rituximab) plus cyclophosphamide, doxorubicin and prednisone (R-CHP) versus MabThera/Rituxan plus cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP), met its primary endpoint by demonstrating significantly improved an d clinically meaningful progression-free survival in people with previously untreated diffuse large B-cell lymphoma (DLBCL). Safety outcomes were consistent with those seen in previous...
Source: Roche Investor Update - August 9, 2021 Category: Pharmaceuticals Source Type: news

[Ad hoc announcement pursuant to Art. 53 LR] Phase III study shows Roche's Polivy plus R-CHP is the first regimen in 20 years to significantly improve outcomes in previously untreated aggressive form of lymphoma compared to standard of care
Basel, 9 August 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the pivotal phase III POLARIX trial investigating Polivy ® (polatuzumab vedotin) in combination with MabThera®/Rituxan® (rituximab) plus cyclophosphamide, doxorubicin and prednisone (R-CHP) versus MabThera/Rituxan plus cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP), met its primary endpoint by demonstrating significantly improved an d clinically meaningful progression-free survival in people with previously untreated diffuse large B-cell lymphoma (DLBCL). Safety outcomes were consistent with those seen in previous...
Source: Roche Media News - August 9, 2021 Category: Pharmaceuticals Source Type: news

Emerging roles of PLC{gamma}1 in endothelial biology
Phospholipase C 1 (PLC1) is a member of the PLC family that functions as signal transducer by hydrolyzing membrane lipid to generate second messengers. The unique protein structure of PLC1 confers a critical role as a direct effector of VEGFR2 and signaling mediated by other receptor tyrosine kinases. The distinct vascular phenotypes in PLC1-deficient animal models and the gain-of-function mutations of PLC1 found in human endothelial cancers point to a major physiological role of PLC1 in the endothelial system. In this review, we discuss aspects of physiological and molecular function centering around PLC1 in the context o...
Source: Signal Transduction Knowledge Environment - August 3, 2021 Category: Science Authors: Chen, D., Simons, M. Tags: STKE Reviews Source Type: news

FDA accepts application for Roche ’s faricimab for the treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME)
Basel, 29 July 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has accepted the company ’s Biologics License Application (BLA), under Priority Review, for faricimab for the treatment of neovascular or “wet” age-related macular degeneration (nAMD) and diabetic macular edema (DME). The FDA has also accepted the company’s submission for diabetic retinopathy.Faricimab will be the first and only bispecific antibody designed for the eye, if approved. It targets two distinct pathways – via angiopoietin-2 (Ang-2) and vascular endothelial growt...
Source: Roche Media News - July 29, 2021 Category: Pharmaceuticals Source Type: news

FDA accepts application for Roche ’s faricimab for the treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME)
Basel, 29 July 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has accepted the company ’s Biologics License Application (BLA), under Priority Review, for faricimab for the treatment of neovascular or “wet” age-related macular degeneration (nAMD) and diabetic macular edema (DME). The FDA has also accepted the company’s submission for diabetic retinopathy.Faricimab will be the first and only bispecific antibody designed for the eye, if approved. It targets two distinct pathways – via angiopoietin-2 (Ang-2) and vascular endothelial growt...
Source: Roche Investor Update - July 29, 2021 Category: Pharmaceuticals Source Type: news

Richard Lewontin obituary
Pioneering biologist and geneticist whose research showed the emptiness of traditional biological concepts of raceThe American scientist Richard Lewontin, who has died aged 92, was intimately involved in some of the most important discoveries, and feuds, of evolutionary biology during the decades in which it passed from knowing that genes existed to specifying them in precise molecular terms.His greatest contribution came in the 1960s, when he demonstrated the existence of very widespread genetic variation within species as well as between them. This research, with John Hubby at the University of Chicago, which had started...
Source: Guardian Unlimited Science - July 28, 2021 Category: Science Authors: Andrew Brown and Steven Rose Tags: Genetics Science Biology US news Harvard University Research Education Source Type: news

Marnie Halpern Named the Andrew Thomson, Jr., MD 1946 Professor
Renowned researcher Marnie Halpern, PhD, chair and professor of molecular and systems biology at Dartmouth’s Geisel School of Medicine, has been named the Andrew Thomson, Jr., MD 1946 Professor. (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - July 22, 2021 Category: Hospital Management Authors: Timothy Dean Tags: News Marnie Halpern professorship Source Type: news

Early-life social connections influence gene expression, stress resilience
(University of Colorado at Boulder) Having friends may not only be good for the health of your social life, but also for your actual health--if you're a hyena, that is. Strong social connections and greater maternal care early in life can influence molecular markers related to gene expression in DNA and future stress response, suggests a new University of Colorado Boulder study of spotted hyenas in the wild. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 22, 2021 Category: Biology Source Type: news

SMART breakthrough in detection of SARS-CoV-2 variant in wastewater
(Singapore-MIT Alliance for Research and Technology (SMART)) Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, alongside collaborators from Biobot Analytics, Nanyang Technological University (NTU) and Massachusetts Institute of Technology (MIT), have successfully developed an innovative, open-source molecular detection method that is able to detect and quantify the B.1.1.7 (Alpha) variant of SARS-CoV-2. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 21, 2021 Category: Biology Source Type: news

Zero-dimensional molecular sieve membranes enhance gas separation selectivity
(Dalian Institute of Chemical Physics, Chinese Academy Sciences) Scientists proposed zero-dimensional molecular sieve membranes that could enhance the separation selectivity of hydrogen and carbon dioxide. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 21, 2021 Category: Biology Source Type: news