Plasmid Analysis Using the Agilent Fragment Analyzer System
Verifying plasmid quality is critical for molecular biology and biomanufacturing applications. (Source: The Scientist)
Source: The Scientist - March 13, 2023 Category: Science Tags: The Marketplace Source Type: news
Compilation of CDER New Molecular Entity (NME) Drug and New Biologic Approvals
This dataset provides a listing of all New Molecular Entities (NMEs) approved from 1985 – 2019 and regulated by the Center for Drug Evaluation and Research (CDER). The listed NMEs include both small molecule drugs approved under a New Drug Application (NDA) and new biological products approved under (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 13, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news
The battle to boost our deep sleep – and help stop dementia
The biological ‘brainwashing’ that happens while you are sleeping is crucial for filtering out toxins. Here’s how to optimise your overnight cycleTonight, and almost every night, something amazing will happen inside your brain. As you turn off the light switch and fall asleep, you will be switching on the neurological equivalent of a dishwasher deep-clean cycle. First, the activity of billions of brain cells will begin to synchronise, and oscillate between bursts of excitation and rest. Coupled with these “slow waves”, blood will begin to flow in and out of your brain, allowing pulses of the straw-coloured cerebr...
Source: Guardian Unlimited Science - March 13, 2023 Category: Science Authors: Linda Geddes Tags: Sleep Neuroscience Human biology Health & wellbeing Life and style Society Dementia Source Type: news
Molecular Biologist Michael Green Dies at 69
Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. (Source: The Scientist)
Source: The Scientist - March 8, 2023 Category: Science Tags: News & Opinion Source Type: news
Alpaca-derived antibodies could protect plants from disease
COVID-19 has tragically given many people a crash course in the importance of antibodies, pathogen-targeting proteins produced by the sophisticated immune systems of humans and other animals. Now, researchers from a U.K. plant research institute have found a way to endow plants with an antibody-based defense for a specific threat, potentially speeding the creation of crops resistant to any kind of emerging virus, bacterium, or fungus.
“It’s a really creative and bold approach,” says Jeff Dangl, a plant immunologist at the University of North Carolina, Chapel Hill. Roger Innes, a plant geneticist at Indiana Univ...
Source: ScienceNOW - March 2, 2023 Category: Science Source Type: news
Ancient DNA upends European prehistory
Thirty thousand years ago, Europe was a land of open steppes with herds of grazing mammoth and other megafauna—and a strikingly uniform human culture. Its inhabitants, whom archaeologists call the Gravettians, dwelled in caves or in shelters built of mammoth bones. They carved palm-size sculptures from mammoth tusk, depicting mammoths, cave lions, and stylized female figurines with elaborate headdresses and exaggerated breasts and buttocks, and left their distinctive art and artifacts from Spain to western Russia. “You can make a case for saying the Gravettian is the first pan-European culture,” says University of T...
Source: ScienceNOW - March 1, 2023 Category: Science Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
