Mount Sinai Scientists Unlock Secrets of Red Blood Cell Transporter, Potentially Paving the Way for New Drugs
Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings, which were reported in the September 7 issue of Nature Structural & Molecular Biology, could... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - September 8, 2023 Category: Pharmaceuticals Tags: TRI Source Type: news
Life science company founder: Lowering cost of DNA sequencing leads to groundbreaking advancements in personalized medicine
Radoje Drmanac received a Ph.D. in molecular biology from Belgrade University in Serbia in 1988. As a Ph.D. student, he invented a powerful DNA sequencing platform to identify the thousands of DNA variants that impact human health.
In 1990, the international Human Genome Project was launched to discover the estimated 20,000 to 25,000 human genes and make them accessible for further biological study. The project brought Drmanac to Argonne National Labs in Illinois, where he lent his expertise for … (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 8, 2023 Category: Biotechnology Authors: Laura Newpoff Source Type: news
Human ancestors may have survived a brush with extinction 900,000 years ago
About 1 million years ago, our distant ancestors hunted in small bands and gathered their food with sophisticated stone tools. Then, about 900,000 years ago, something happened: The number of breeding individuals dwindled to only about 1300, according to a new study modeling ancient population sizes. Our ancestors came within a hair’s breadth of extinction, and populations remained that low for the next 100,000 years or more, researchers argue today in
Science
.
The work, which relies on a new statistical method for estimating ancient population sizes, provides insight into a critical time for our lineage...
Source: ScienceNOW - August 31, 2023 Category: Science Source Type: news
News at a glance: Moon landing, museum thefts, and gardening for conservation
SPACE SCIENCE
Indian Moon lander begins search for ice
India last week put a spacecraft on the Moon, making it the fourth nation to perform the feat, after the United States, the Soviet Union, and China. The $75 million, robotic Chandrayaan-3 mission is the first to explore a region near the lunar south pole, which is thought to hold frozen water that could be used to support human explorers. The area also contains large impact craters, which could hold clues to the history of the Solar System. Hours after landing, the craft released a solar-powered, suitcase-size rover that will study soil compositi...
Source: ScienceNOW - August 31, 2023 Category: Science Source Type: news
Genetics and epigenetics of human aggression - Odintsova VV, Hagenbeek FA, Van der Laan CM, van de Weijer S, Boomsma DI.
There is substantial variation between humans in aggressive behavior, with its biological etiology and molecular genetic basis mostly unknown. This review chapter offers an overview of genomic and omics studies revealing the genetic contribution to aggress... (Source: SafetyLit)
Source: SafetyLit - August 28, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Why do cats love tuna so much? Scientists may finally know
Apart from Garfield’s legendary love of lasagna, perhaps no food is more associated with cats than tuna. The dish is a staple of everything from
The New Yorker
cartoons
to
Meow Mix jingles
—and more than 6% of all wild-caught fish goes into cat food. Yet tuna (or any seafood for that matter) is an odd favorite for an animal that evolved in the desert. Now, researchers say they have found a biological explanation for this curious craving.
In a study published this month in
Chemical Senses
, scientists report that
cat taste buds contain the receptors needed to detect umam...
Source: ScienceNOW - August 25, 2023 Category: Science Source Type: news
‘Magic’ Mushrooms Set Forest Aglow in Mesmerizing Display – Metro
Read article - Jay Dunlap, a professor of molecular and systems biology and of biochemistry and cell biology, is featured in an article about a rush of bioluminescent mushrooms carpeting the forest floor in the Mhadei Wildlife Sanctuary in northeastern Goa, India. “It looks like the mushroom is making its own light, and it’s quite magical,” Dunlap said. (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - August 17, 2023 Category: Hospital Management Authors: Geisel Communications Tags: News Source Type: news
New study identifies genes linked to high production of key antibody
Key takeawaysResearchers studying white blood cells identified an atlas of genes linked to high production and release of the most common type of antibody found in the human body, known as immunoglobulin G.The finding could be a step toward new antibody-based treatments and improvements in the effectiveness of cell therapies.The researchers used microscopic containers called nanovials, which were developed at UCLA, to capture the individual cells they studied.A collaboration led by UCLA and the Seattle Children ’s Research Institute has yielded new knowledge about the genes responsible for the production and release of i...
Source: UCLA Newsroom: Health Sciences - August 14, 2023 Category: Universities & Medical Training Source Type: news
News at a glance: A win for obesity drugs, NIH unionization roadblocks, and Mexican fireflies under threat
CONSERVATION
Researchers raise alarm over threat to Mexican fireflies
Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species
Photinus palaciosi
. Endemic to Mexico’s Tlaxcala forests,
P. palaciosi
is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ ...
Source: ScienceNOW - August 10, 2023 Category: Science Source Type: news
The big idea: should we bring extinct creatures back to life?
We might be able to genetically engineer something like woolly mammoths, but is it a good idea?We may weep for the dodo, but could and should we bring this lovely bird back from the dead? De-extinction is the science ofrestoring lost species and it has been in the news, sporadically, for decades.The story in modern times began in 1990 whenMichael Crichton published his science fiction novel Jurassic Park, in which he imagined a world where scientists were able to bring dinosaurs back to life. Crichton had trained as a biomedical scientist, so he was aware of the then newpolymerase chain reaction (PCR) technology that was r...
Source: Guardian Unlimited Science - August 7, 2023 Category: Science Authors: Mike Benton Tags: Extinct wildlife Science and nature books Biotechnology industry Genetics Culture Source Type: news
This longevity scientist tells Dr. Sanjay Gupta his mission is to'cure aging' through biohacking
What do molecular hydrogen, nutrient drips, and a cocktail of supplements all have in common? They are all part of the Fountain of Youth quest as people “biohack” their lives in the name of longevity. Optimizing your biology or biohacking is often seen as “skirting along the edges of science, and…#fountainofyouth #sanjaygupta #chasinglife #fda #nirbarzilai #barzilai #doriangray #peterpan (Source: Reuters: Health)
Source: Reuters: Health - August 1, 2023 Category: Consumer Health News Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche reports strong growth in both divisions ’ base business; Group sales and profit reflect declining demand for COVID-19 products
Excluding COVID-19 products,Groupsales increase strongly by 8%1at constant exchange rates (CER)In line with the expected declining demand for COVID-19 products,Groupsales decrease 2% (-8% in Swiss francs)Pharmaceuticals Division sales grow strongly by 8% due to continued high demand for newer medicines; new eye medicine Vabysmo is the strongest growth driverDiagnostics Division ’s base businesscontinues its good growth momentum with an increase of 6%, while total divisional sales are 23% lower due to exceptionally high demand for COVID-19 tests in the first half of 2022Core earnings per share decrease 5%, driven by lower...
Source: Roche Investor Update - July 27, 2023 Category: Pharmaceuticals Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche reports strong growth in both divisions ’ base business; Group sales and profit reflect declining demand for COVID-19 products
Basel, 27 July 2023Excluding COVID-19 products,Groupsales increase strongly by 8%1at constant exchange rates (CER)In line with the expected declining demand for COVID-19 products,Groupsales decrease 2% (-8% in Swiss francs)Pharmaceuticals Division sales grow strongly by 8% due to continued high demand for newer medicines; new eye medicine Vabysmo is the strongest growth driverDiagnostics Division ’s base businesscontinues its good growth momentum with an increase of 6%, while total divisional sales are 23% lower due to exceptionally high demand for COVID-19 tests in the first half of 2022Core earnings per share decrease ...
Source: Roche Media News - July 27, 2023 Category: Pharmaceuticals Source Type: news
Development of a procedure involving artifact examination to determine the species affiliation of its biological material, as illustrated by an attempt to demystify an alleged Nazi lampshade made from human skin - Trzci ński M, Karpiewska A, Hałoń A, Jonkisz A, Lebioda A, Jurek T, Dobosz T.
OBJECTIVES: The main purpose of the study was to identify the species origin of the material from which the incriminating lampshade bought at a flea market had been made. METHODS: The histological and molecular biology methods commonly used in fore... (Source: SafetyLit)
Source: SafetyLit - July 10, 2023 Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news
Extra chromosomes —long a mystery in tumors—may help them grow
Cancer cells are sloppy with their DNA, often gaining entire chromosomes as they proliferate. Now, researchers have found that this extra DNA can rev up the cells' growth and stymie one of the body's main anticancer defenses. This chromosomal hoarding may leave some tumors susceptible to certain drugs, however, opening the possibility of tailored treatments.
The study, in which researchers used gene editing to compare cells with and without extra chromosomes, "is important, it's novel, and it was carried out in a very elegant way," says cell biologist Uri Ben-David of Tel Aviv University, who wasn't connected to the ...
Source: ScienceNOW - July 6, 2023 Category: Science Source Type: news
