Fight Aging! Newsletter, April 22nd 2019

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is published under the Creative Commons Attribution 4.0 International License. You are encouraged to republish and rewrite it in any way you see fit, the only requirements being that you provide attribution and a link to Fight Aging! To subscribe or unsubscribe please visit: https://www.fightaging.org/newsletter/ Contents Calorie Restriction Affects the Plasticity of Fat Tissue, Not Just the Amount of Fat Tissue The Healthy Longevity Global Grand Challenge at the National Academy of Medicine A Few of the Many Interviews Conducted at the Undoing Aging 2019 Conference A Selection of Recent Research into the Impact of Diet and Exercise on Aging To What Degree is Chronic Inflammation the Cause of Thymic Involution with Age? An Interview with Felix Werth of the German Party for Health Research The Progression of Alzheimer's Disease ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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This study investigates the distribution of femoral metastases in cancer patients, specifically addressing the incidence of distal femoral metastases. PET/CT examinations routinely extend only to mid-thigh level, precluding detection of distal metastases. We found a total of 208 femoral metastases in 112 patients. 30% had distal femoral metastases in addition to other areas of involvement. 7% of patients with femoral metastases had only distal femur disease. 6 patients had distal pathologic fractures. Exclusion of the distal femur during PET/CT may result in a missed or delayed diagnosis that could contribute to the develo...
Source: Cancer Investigation - Category: Cancer & Oncology Tags: Cancer Invest Source Type: research
ABSTRACTX ‐linked hypophosphatemia (XLH) is characterized by increased activity of circulating FGF23 resulting in renal phosphate wasting and abnormal bone mineralization. Hyperparathyroidism may develop in XLH patients; however its prevalence, pathogenesis and clinical presentation are not documented.This observational study (CNIL 2171036 v 0) recruited XLH adult patients in a single tertiary referral center. Each patient was explored in standardized conditions and compared with two healthy volunteers, matched for sex, age and 25 ‐OH vitamin D concentrations. The primary endpoint was the proportion of patients with hy...
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
In conclusion, implementation of FLS was associated with a reduced risk of recurrent fracture, indicating that FLSs should be included routinely at hospitals treating fracture patients.This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
Authors: Xu H, Dong L, Bin Z, Yansong H, Shaofeng L, Chang L, Chen C, Changli W Abstract Despite the excellent efficacy and low toxicity of photoresponse therapy, which has attracted considerable attention for use in non-small cell lung cancer (NSCLC) therapy, unsatisfactory cellular permeability, and instability, both in vitro and in vivo have limited further clinical applications of indole cyanine photosensitizers. Here, we explore the supramolecular self-assembly of a 'hyalurosome' that is mediated by calcium phosphate nanonuclei. Through hyaluronate-mediated CD44 targeting, the constructed hyalurosome...
Source: Drug Delivery - Category: Drugs & Pharmacology Tags: Drug Deliv Source Type: research
To compare pre- and postoperative MRI-based anatomical findings following native tissue prolapse repair.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Non-Oral Poster Source Type: research
To evaluate whether oxycodone use for postoperative pain control after hysterectomy for benign disease differs based on hysterectomy route.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Non-Oral Poster Source Type: research
To compare the outcomes of laparoscopic retroperitoneal hysterectomy (LRH) in morbidly obese patients (BMI ≥ 40 k/m2) versus non-obese patients (BMI
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Non-Oral Poster Source Type: research
To assess factors and charges associated with hospital revisits following benign hysterectomy in the United States.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Non-Oral Poster Source Type: research
The aim of this study is to assess whether the use of MRI as part of preoperative workup in the setting of patients with chronic pelvic pain and presumed diagnosis of endometriosis is predictive of pathology-proven endometriosis.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Non-Oral Poster Source Type: research
To compare changes in body image among women with uterovaginal prolapse undergoing vaginal mesh hysteropexy (mesh hysteropexy) or vaginal hysterectomy with uterosacral ligament suspension (hysterectomy).
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Non-Oral Poster Source Type: research
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