Fight Aging! Newsletter, April 22nd 2019

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is published under the Creative Commons Attribution 4.0 International License. You are encouraged to republish and rewrite it in any way you see fit, the only requirements being that you provide attribution and a link to Fight Aging! To subscribe or unsubscribe please visit: https://www.fightaging.org/newsletter/ Contents Calorie Restriction Affects the Plasticity of Fat Tissue, Not Just the Amount of Fat Tissue The Healthy Longevity Global Grand Challenge at the National Academy of Medicine A Few of the Many Interviews Conducted at the Undoing Aging 2019 Conference A Selection of Recent Research into the Impact of Diet and Exercise on Aging To What Degree is Chronic Inflammation the Cause of Thymic Involution with Age? An Interview with Felix Werth of the German Party for Health Research The Progression of Alzheimer's Disease ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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Many experts now view the individual mandate as a policy that did little to increase health coverage — but did a lot to invite political backlash.
Source: NYT - Category: American Health Authors: Tags: Health Insurance and Managed Care Patient Protection and Affordable Care Act (2010) United States Economy Fines (Penalties) United States Politics and Government Source Type: news
Authors: Hwang S, Ren T, Gao B Abstract Obesity and binge drinking often coexist and work synergistically to promote steatohepatitis; however, the underlying mechanisms remain obscure. In this mini-review, we briefly summarize clinical evidence of the synergistical effect of obesity and heavy drinking on steatohepatitis and discuss the underlying mechanisms obtained from the study of several mouse models. High-fat diet (HFD) feeding and binge ethanol synergistically induced steatohepatitis and fibrosis in mice with significant intrahepatic neutrophil infiltration; such HFD-plus-ethanol treatment markedly up-regulat...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
CONCLUSIONS: The COI of liver diseases in Japan has been decreasing for the past 15 years. In the future, a further reduction in patients with hepatitis C is expected, and even if the incidence of NASH and alcoholic liver disease increases, that of cirrhosis and liver cancer will likely continue to decrease. PMID: 32942026 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Publication date: November 2020Source: Research in Developmental Disabilities, Volume 106Author(s): Franceli L. Cibrian, Melisa Madrigal, Marina Avelais, Monica Tentori
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
CONCLUSION: Our study expands the mutation spectrum of WSF1 mutations with three novel mutations. Homozygosity mapping may provide enrichment for molecular genetic analysis and early diagnosis of WS1 patients with incomplete phenotype, particularly in consanguineous pedigrees. PMID: 32938580 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
This study aims to determine the incidence of T1D in children under the age of 15 years, living in Tlemcen in Northwest Algeria. METHODS: A retrospective study conducted on data of children (
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Authors: Theodosis-Nobelos P, Filotheidou A, Triantis C Abstract The clinical role of the placebo effect is a topic of increasing interest for the scientific community. Focus is shifting from the inert role of placebos in randomized controlled trials (RCTs) to potential effects in clinical applications, since the phenomenon is thought to be inherent in routine clinical practice, affecting therapy success rates. Mediation of the mind-brain-body relationship involves both psychosocial and neurobiological factors, the interaction of which comprises the placebo mechanisms. Psychosocial factors include environmentally i...
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
Publication date: Available online 17 September 2020Source: Stem Cell ResearchAuthor(s): Huifang Zhao, Lang He, Hualin Huang, Shuai Li, Na Cheng, Feng Tang, Xiaobo Han, Zuoxian Lin, Rongqi Huang, Peng Zhou, Sihao Deng, Jufang Huang, Zhiyuan Li
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 17 September 2020Source: Stem Cell ReportsAuthor(s): Andrejs Ivanovs, Stanislav Rybtsov, Richard A. Anderson, Alexander Medvinsky
Source: Stem Cell Reports - Category: Stem Cells Source Type: research
Publication date: Available online 17 September 2020Source: Stem Cell ReportsAuthor(s): Dominic C.H. Ng, Dominic K. Richards, Richard J. Mills, Uda Y. Ho, Hannah L. Perks, Callum R. Tucker, Holly K. Voges, Julia K. Pagan, James E. Hudson
Source: Stem Cell Reports - Category: Stem Cells Source Type: research
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