Costs of raw material for drugs rise by up to 140%
API prices of certain drugs like fever and pain relief drug paracetamol and life-saving antibiotic Meropenem (also used for Covid), and anti-diabetic metformin, have more than doubled to as high as 139%, 127% and 124% respectively, putting the spotlight back on India ’s near total-dependence on the Dragon. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 20, 2021 Category: Pharmaceuticals Source Type: news

Metformin Use May Curb BCC Risk Metformin Use May Curb BCC Risk
The decrease in basal cell carcinoma (BCC) risk was seen across all metformin dosing levels, but the reason for this remains unclear.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 15, 2021 Category: Cancer & Oncology Tags: Dermatology News Source Type: news

After Metformin, Which Drug Makes the GRADE? After Metformin, Which Drug Makes the GRADE?
Which medication should be added after metformin? The GRADE study attempts to fill the evidence gap.Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 9, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology Commentary Source Type: news

Cadila Healthcare arm recalls 21,240 bottles of diabetes drug in US
Metformin hydrochloride extended-release tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type-2 diabetes mellitus. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 4, 2021 Category: Pharmaceuticals Source Type: news

Synjardy XR (empagliflozin and metformin extended-release)
Title: Synjardy XR (empagliflozin and metformin extended-release)Category: MedicationsCreated: 7/2/2021 12:00:00 AMLast Editorial Review: 7/2/2021 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - July 2, 2021 Category: Endocrinology Source Type: news

What's Best for Diabetes After Metformin? GRADE Outdated at Outset What's Best for Diabetes After Metformin? GRADE Outdated at Outset
The GRADE trial compared four different agents as add-ons to metformin for type 2 diabetes, and while liraglutide and insulin glargine fared best, the study is already outdated, said one commentator.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 30, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

SGLT2 Inhibitor Better Second-Line Diabetes Pick Than Sulfonylurea When Cost Is Not an Issue SGLT2 Inhibitor Better Second-Line Diabetes Pick Than Sulfonylurea When Cost Is Not an Issue
When metformin fails to sufficiently lower blood glucose levels, it's better to add an SGLT2 inhibitor rather than a sulfonylurea, according to a comparative effectiveness analysis.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 30, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Synjardy (empagliflozin and metformin)
Title: Synjardy (empagliflozin and metformin)Category: MedicationsCreated: 6/30/2021 12:00:00 AMLast Editorial Review: 6/30/2021 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - June 30, 2021 Category: Drugs & Pharmacology Source Type: news

Best Blood Sugar Meds for Type 2 Diabetes
Taking metformin for type 2 diabetes but still having trouble controlling your blood sugar? New research reveals which drugs may be most helpful. (Source: WebMD Health)
Source: WebMD Health - June 30, 2021 Category: Consumer Health News Source Type: news

Which Blood Sugar Meds Work Best Against Type 2 Diabetes?
TUESDAY, June 29, 2021 -- You have type 2 diabetes, and you are already taking an old standby drug, metformin. But you still need help controlling your blood sugar levels. Which medication would be the best? New research pitted several diabetes... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 29, 2021 Category: General Medicine Source Type: news

' Stunning' Twincretin Beats Semaglutide in Type 2 Diabetes'Stunning' Twincretin Beats Semaglutide in Type 2 Diabetes
Head-to-head pivotal trial results show weekly tirzepatide injections surpassed 1 mg semaglutide weekly for A1c reduction and weight loss as second-line therapy after metformin in type 2 diabetes.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - June 27, 2021 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

Discontinuing Metformin: The Crowdsourced View Discontinuing Metformin: The Crowdsourced View
Readers were divided on the decision to stop an elderly woman's metformin and reduce her pill burden.Medscape Family Medicine (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - June 23, 2021 Category: Primary Care Tags: Family Medicine/Primary Care Article Source Type: news

FDA Recalls More Metformin Extended-Release Tablets FDA Recalls More Metformin Extended-Release Tablets
Two lots of metformin HCl extended-release tablets have been recalled by Viona Pharmaceuticals because unacceptable levels of nitrosodimethylamine, a likely carcinogen, were found in the 750-mg tablets.News Alerts (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - June 15, 2021 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Alert Source Type: news

Viona Pharmaceuticals Inc., Issues Voluntary Nationwide Recall of Metformin HCl Extended-Release Tablets, USP 750 mg, Due to the Detection of N-Nitrosodimethylamine (NDMA) Impurity
Viona Pharmaceuticals Inc., is voluntarily recalling 2 (two) lots of Metformin Hydrochloride Extended-Release Tablets, USP 750 mg to the retail level. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - June 11, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Common diabetes drug shows promise as treatment for COVID-19 lung inflammation
Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans. Metformin works by lowering glucose production in the liver, reducing blood sugar levels that, in turn, improve the body's response to insulin. (Source: World Pharma News)
Source: World Pharma News - June 10, 2021 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Common diabetes drug shows promise as treatment for COVID-19 lung inflammation
(University of California - San Diego) Researchers identify molecular mechanism for the anti-inflammatory activity of diabetes drug metformin and, in mouse studies, say it prevents lung inflammation in animals infected with SARS-CoV-2, the virus that causes COVID-19. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 10, 2021 Category: Infectious Diseases Source Type: news

' Remarkable' Response to Diabetes Drug for Bipolar Depression'Remarkable' Response to Diabetes Drug for Bipolar Depression
Patients with treatment-resistant bipolar depression with insulin resistance showed marked improvement in depressive symptoms after their insulin-resistance was mitigated by treatment with metformin.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - June 7, 2021 Category: Internal Medicine Tags: Psychiatry News Source Type: news

AstraZeneca Pharma, Abbott Healthcare terminate distribution agreements for diabetes drug in India
AstraZeneca India will continue to independently market Dapagliflozin, the combinations of Dapagliflozin and Metformin as well as Dapagliflozin and Saxagliptin in India under the brand names Forxiga, Xigduo and Qtern respectively, the filing said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - May 28, 2021 Category: Pharmaceuticals Source Type: news

U of M Medical School receives $1.5M for nation's first ivermectin COVID-19 clinical trial
(University of Minnesota Medical School) An ongoing COVID-19 clinical trial studying the outpatient use of metformin, a generic medication for type 2 diabetes, has expanded and will now be the nation's first to include fluvoxamine, an antidepressant, and ivermectin, an antiparasitic, as possible treatment options to prevent hospitalization and " long COVID. " (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 25, 2021 Category: International Medicine & Public Health Source Type: news

Sun Pharma recalls 50,868 bottles of diabetes drug in US
Drug major Sun Pharma is recalling 50,868 bottles of diabetes drug Metformin HCl extended-release tablets in the US market, according to the US Food and Drug Administration (USFDA). (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - May 21, 2021 Category: Pharmaceuticals Source Type: news

Right Time to Deprescribe This Frail Patient's Metformin? Right Time to Deprescribe This Frail Patient's Metformin?
Check out this case, and see whether you agree with Dr Vega's opinion on deprescribing metformin in an elderly patient.Medscape Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2021 Category: Consumer Health News Tags: Family Medicine/Primary Care Article Source Type: news

Diabetes drug shows potential in fighting cancer
(Massachusetts General Hospital) Phenformin, in combination with immunotherapies like PD-1 immune checkpoint inhibitors, shows greater promise than phenformin or metformin alone. A clinical trial is under way at MGH to evaluate the use of phenformin with an inhibitor of the BRAF-mutated gene, present in roughly half of all melanomas. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 14, 2021 Category: Cancer & Oncology Source Type: news

How to live longer: Anti-diabetic drug shown to reduce cancer risk to boost longevity
HOW TO live longer could be as simple as popping a pill daily, according to studies. Metformin has shown impressive results to help not only reduce cancer and cardiovascular disease risk, but also in helping to delay the ageing process. How? (Source: Daily Express - Health)
Source: Daily Express - Health - April 6, 2021 Category: Consumer Health News Source Type: news

Diabetes drug may be a new weapon against HIV
(University of North Carolina Health Care) A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2021 Category: International Medicine & Public Health Source Type: news

Metformin trial dramatically reduces seizures in tuberous sclerosis
(University College London) A team of researchers led by UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) has found that metformin - a drug commonly used to treat Type 2 diabetes - can successfully reduce symptoms associated with tuberous sclerosis complex (TSC), including reduction in the frequency of seizures and the size of brain tumours. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2021 Category: International Medicine & Public Health Source Type: news

HIV: An antidiabetic drug to reduce chronic inflammation
(University of Montreal Hospital Research Centre (CRCHUM)) Metformin, a drug used to treat type-2 diabetes, could help reduce chronic inflammation in people living with HIV (PLWH) who are being treated with antiretroviral therapy (ART), according to researchers at the University of Montreal Hospital Research Centre (CRCHUM). (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 18, 2021 Category: Infectious Diseases Source Type: news

Anion Gap in Diagnosis of Metformin-associated Lactic Acidosis Anion Gap in Diagnosis of Metformin-associated Lactic Acidosis
This study casts doubt on the utility of anion gap measurement as an approach for diagnosis of metformin-associated lactic acidosis.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 4, 2021 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Goldenseal May Interfere With Metformin, Jeopardize Glucose Control Goldenseal May Interfere With Metformin, Jeopardize Glucose Control
The natural botanical product may interfere with intestinal absorption of metformin, potentially compromising blood glucose control in patients with type 2 diabetes, according to investigators.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - February 24, 2021 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

Goldenseal Interferes With Metformin for Diabetes
Does Goldenseal Interfere With Metformin for Diabetes? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 24, 2021 Category: General Medicine Source Type: news

Predictors of Death, Discharge ID ’ d for Diabetes Patients With COVID - 19
Younger age, routine metformin therapy, and longer symptom duration on admission positively linked to discharge (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 23, 2021 Category: Respiratory Medicine Tags: Endocrinology, Infections, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Pharmacy, Pulmonology, Geriatrics, Journal, Source Type: news

Metformin for Diabetes Has No Effect on COVID-19 Infection, Death Metformin for Diabetes Has No Effect on COVID-19 Infection, Death
With propensity score matching and inclusion of nonhospitalized primary care patients, metformin use did not influence COVID-19 susceptibility or mortality in those with diabetes.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 17, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Study Looks at T2DM, Metformin Use, and Breast Cancer Risk
Links between T2DM with metformin use and breast cancer risk appear to be affected by hormone receptor status (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 10, 2021 Category: Cancer & Oncology Tags: Endocrinology, Family Medicine, Gynecology, Internal Medicine, Oncology, Pharmacy, Journal, Source Type: news

Study Looks at T2DM, Metformin Use, and Breast Cancer Risk
WEDNESDAY, Feb. 10, 2021 -- The risks for breast cancer in women with type 2 diabetes (T2D) may be influenced by long-term metformin use, according to a study published online Jan. 28 in the Annals of Oncology. Yong-Moon Mark Park, M.D., Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 10, 2021 Category: Pharmaceuticals Source Type: news

Long-Term Metformin Use Linked to Fewer ER+ Breast Cancers Long-Term Metformin Use Linked to Fewer ER+ Breast Cancers
Observational data from over 40,000 women with type 2 diabetes documents fewer estrogen receptor-positive breast cancers in those treated with metformin long-term; editorialists question conclusions, however.Medscape Medical News (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - February 3, 2021 Category: Radiology Tags: Hematology-Oncology News Source Type: news

Metformin Tied to Longer Gestation in Women With Preeclampsia Metformin Tied to Longer Gestation in Women With Preeclampsia
The small study does not suggest it's time for any clinical practice changes but provides evidence that it may be possible to reduce preterm births due to preeclampsia.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 2, 2021 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Diabetes Drug Metformin Could Help Prevent Breast Cancer
Title: Diabetes Drug Metformin Could Help Prevent Breast CancerCategory: Health NewsCreated: 2/1/2021 12:00:00 AMLast Editorial Review: 2/2/2021 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - February 2, 2021 Category: Cancer & Oncology Source Type: news

Type 2 Diabetes Drug Metformin Could Help Prevent Some Breast Cancers
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 2, 2021 Category: Cancer & Oncology Tags: Gynecology, Oncology, Diabetes, News, Source Type: news

Metformin Could Help Prevent Some Breast Cancers
Women with type 2 diabetes may be more likely to develop breast cancer, but taking the diabetes drug metformin appears to reduce their risk for the most common type, new research finds. (Source: WebMD Health)
Source: WebMD Health - February 1, 2021 Category: Consumer Health News Source Type: news

Type 2 Diabetes Drug Metformin Could Help Prevent Some Breast Cancers
MONDAY, Feb. 1, 2021 -- Women with type 2 diabetes may be more likely to develop breast cancer, but taking the diabetes drug metformin appears to reduce their risk for the most common type, new research finds. Compared to women without diabetes,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 1, 2021 Category: General Medicine Source Type: news

Metformin may affect risk of breast cancer in women with type 2 diabetes
(European Society for Medical Oncology) A study in Annals of Oncology of 44,541 women has found that there appears to be no association between type 2 diabetes and developing breast cancer overall. This may be because most women in the study with type 2 diabetes were taking metformin, a medication widely used to treat type 2 diabetes, whose actions may help to reduce the risk of developing oestrogen positive (ER-positive) breast cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 28, 2021 Category: Cancer & Oncology Source Type: news

Metformin Use for T2DM May Reduce COVID - 19 Mortality
Odds of contracting COVID - 19, COVID - 19 - related mortality higher for individuals with diabetes (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - January 27, 2021 Category: Respiratory Medicine Tags: Endocrinology, Family Medicine, Geriatrics, Gynecology, Infections, Internal Medicine, Critical Care, Nursing, Pharmacy, Pulmonology, Journal, Source Type: news

Metformin Use for T2DM May Reduce COVID-19 Mortality
WEDNESDAY, Jan. 27, 2021 -- Diabetes is associated with increased odds of contracting COVID-19 and with increased COVID-19 mortality, while metformin treatment before diagnosis of COVID-19 is associated with reduced odds of related mortality,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 27, 2021 Category: Pharmaceuticals Source Type: news

Nostrum Laboratories, Inc. Expands Voluntary Nationwide Recall of Metformin HCl Extended Release Tablets, USP 750 mg, Due to N-Nitrosodimethylamine (NDMA) Content Above the Acceptable Daily Intake (ADI) Limit
Nostrum Laboratories, Inc. is voluntarily recalling one lot of Metformin HCl Extended Release Tablets, USP 750 mg (generic equivalent to Glucophage Tablets) to the consumer level. The Metformin HCl Extended Release Tablets, USP 750 mg (generic equivalent to Glucophage Tablets) have been found to con (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 25, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Metformin Treatment Again Linked to Fewer Deaths From COVID-19 Metformin Treatment Again Linked to Fewer Deaths From COVID-19
The latest of several studies, this time in a very diverse population, shows a striking threefold reduction in deaths from COVID-19 in those taking this leading treatment for type 2 diabetes.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - January 20, 2021 Category: Intensive Care Tags: Infectious Diseases News Source Type: news

Metformin Treatment Again Linked to Fewer Deaths From COVID-19 Metformin Treatment Again Linked to Fewer Deaths From COVID-19
The latest of several studies, this time in a very diverse population, shows a striking threefold reduction in deaths from COVID-19 in those taking this leading treatment for type 2 diabetes.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - January 20, 2021 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Metformin use reduces risk of death for patients with COVID-19 and diabetes
Use of the diabetes drug metformin - before a diagnosis of COVID-19 - is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham. Diabetes is a significant comorbidity for COVID-19. (Source: World Pharma News)
Source: World Pharma News - January 18, 2021 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Metformin use reduces risk of death for patients with COVID-19 and diabetes
(University of Alabama at Birmingham) Use of the diabetes drug metformin -- before a diagnosis of COVID-19 -- is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham. Diabetes is a significant comorbidity for COVID-19. This beneficial effect remained, even after correcting for age, sex, race, obesity, and hypertension or chronic kidney disease and heart failure. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 14, 2021 Category: Infectious Diseases Source Type: news

Granules gets American drug regulator's nod for diabetes management drug Metformin
The US Food and Drug Administration (USFDA) has granted final approval for the company's abbreviated new drug application (ANDA) for Metformin Hydrochloride extended-release tablets USP, 500 mg and 1000 mg, Granules said in a regulatory filing. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - January 13, 2021 Category: Pharmaceuticals Source Type: news

Another Lot of Extended-Release Metformin Is Recalled in the US Another Lot of Extended-Release Metformin Is Recalled in the US
Adding to two lots recalled in November, Nostrum Laboratories has issued a voluntary recall for another lot of extended-release metformin 750 mg due to possible contamination with NDMA.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - January 7, 2021 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

More Metformin Is Recalled
Another Lot of Extended-Release Metformin Is Recalled in the US (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 7, 2021 Category: General Medicine Source Type: news