Diabetes drug shows potential in fighting cancer
(Massachusetts General Hospital) Phenformin, in combination with immunotherapies like PD-1 immune checkpoint inhibitors, shows greater promise than phenformin or metformin alone. A clinical trial is under way at MGH to evaluate the use of phenformin with an inhibitor of the BRAF-mutated gene, present in roughly half of all melanomas. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 14, 2021 Category: Cancer & Oncology Source Type: news

How to live longer: Anti-diabetic drug shown to reduce cancer risk to boost longevity
HOW TO live longer could be as simple as popping a pill daily, according to studies. Metformin has shown impressive results to help not only reduce cancer and cardiovascular disease risk, but also in helping to delay the ageing process. How? (Source: Daily Express - Health)
Source: Daily Express - Health - April 6, 2021 Category: Consumer Health News Source Type: news

Diabetes drug may be a new weapon against HIV
(University of North Carolina Health Care) A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2021 Category: International Medicine & Public Health Source Type: news

Metformin trial dramatically reduces seizures in tuberous sclerosis
(University College London) A team of researchers led by UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) has found that metformin - a drug commonly used to treat Type 2 diabetes - can successfully reduce symptoms associated with tuberous sclerosis complex (TSC), including reduction in the frequency of seizures and the size of brain tumours. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2021 Category: International Medicine & Public Health Source Type: news

HIV: An antidiabetic drug to reduce chronic inflammation
(University of Montreal Hospital Research Centre (CRCHUM)) Metformin, a drug used to treat type-2 diabetes, could help reduce chronic inflammation in people living with HIV (PLWH) who are being treated with antiretroviral therapy (ART), according to researchers at the University of Montreal Hospital Research Centre (CRCHUM). (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 18, 2021 Category: Infectious Diseases Source Type: news

Anion Gap in Diagnosis of Metformin-associated Lactic Acidosis Anion Gap in Diagnosis of Metformin-associated Lactic Acidosis
This study casts doubt on the utility of anion gap measurement as an approach for diagnosis of metformin-associated lactic acidosis.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 4, 2021 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Goldenseal May Interfere With Metformin, Jeopardize Glucose Control Goldenseal May Interfere With Metformin, Jeopardize Glucose Control
The natural botanical product may interfere with intestinal absorption of metformin, potentially compromising blood glucose control in patients with type 2 diabetes, according to investigators.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - February 24, 2021 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

Goldenseal Interferes With Metformin for Diabetes
Does Goldenseal Interfere With Metformin for Diabetes? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 24, 2021 Category: General Medicine Source Type: news

Predictors of Death, Discharge ID ’ d for Diabetes Patients With COVID - 19
Younger age, routine metformin therapy, and longer symptom duration on admission positively linked to discharge (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 23, 2021 Category: Respiratory Medicine Tags: Endocrinology, Infections, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Pharmacy, Pulmonology, Geriatrics, Journal, Source Type: news

Metformin for Diabetes Has No Effect on COVID-19 Infection, Death Metformin for Diabetes Has No Effect on COVID-19 Infection, Death
With propensity score matching and inclusion of nonhospitalized primary care patients, metformin use did not influence COVID-19 susceptibility or mortality in those with diabetes.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 17, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Study Looks at T2DM, Metformin Use, and Breast Cancer Risk
Links between T2DM with metformin use and breast cancer risk appear to be affected by hormone receptor status (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 10, 2021 Category: Cancer & Oncology Tags: Endocrinology, Family Medicine, Gynecology, Internal Medicine, Oncology, Pharmacy, Journal, Source Type: news

Study Looks at T2DM, Metformin Use, and Breast Cancer Risk
WEDNESDAY, Feb. 10, 2021 -- The risks for breast cancer in women with type 2 diabetes (T2D) may be influenced by long-term metformin use, according to a study published online Jan. 28 in the Annals of Oncology. Yong-Moon Mark Park, M.D., Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 10, 2021 Category: Pharmaceuticals Source Type: news

Long-Term Metformin Use Linked to Fewer ER+ Breast Cancers Long-Term Metformin Use Linked to Fewer ER+ Breast Cancers
Observational data from over 40,000 women with type 2 diabetes documents fewer estrogen receptor-positive breast cancers in those treated with metformin long-term; editorialists question conclusions, however.Medscape Medical News (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - February 3, 2021 Category: Radiology Tags: Hematology-Oncology News Source Type: news

Metformin Tied to Longer Gestation in Women With Preeclampsia Metformin Tied to Longer Gestation in Women With Preeclampsia
The small study does not suggest it's time for any clinical practice changes but provides evidence that it may be possible to reduce preterm births due to preeclampsia.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 2, 2021 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Diabetes Drug Metformin Could Help Prevent Breast Cancer
Title: Diabetes Drug Metformin Could Help Prevent Breast CancerCategory: Health NewsCreated: 2/1/2021 12:00:00 AMLast Editorial Review: 2/2/2021 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - February 2, 2021 Category: Cancer & Oncology Source Type: news

Type 2 Diabetes Drug Metformin Could Help Prevent Some Breast Cancers
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 2, 2021 Category: Cancer & Oncology Tags: Gynecology, Oncology, Diabetes, News, Source Type: news

Metformin Could Help Prevent Some Breast Cancers
Women with type 2 diabetes may be more likely to develop breast cancer, but taking the diabetes drug metformin appears to reduce their risk for the most common type, new research finds. (Source: WebMD Health)
Source: WebMD Health - February 1, 2021 Category: Consumer Health News Source Type: news

Type 2 Diabetes Drug Metformin Could Help Prevent Some Breast Cancers
MONDAY, Feb. 1, 2021 -- Women with type 2 diabetes may be more likely to develop breast cancer, but taking the diabetes drug metformin appears to reduce their risk for the most common type, new research finds. Compared to women without diabetes,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 1, 2021 Category: General Medicine Source Type: news

Metformin may affect risk of breast cancer in women with type 2 diabetes
(European Society for Medical Oncology) A study in Annals of Oncology of 44,541 women has found that there appears to be no association between type 2 diabetes and developing breast cancer overall. This may be because most women in the study with type 2 diabetes were taking metformin, a medication widely used to treat type 2 diabetes, whose actions may help to reduce the risk of developing oestrogen positive (ER-positive) breast cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 28, 2021 Category: Cancer & Oncology Source Type: news

Metformin Use for T2DM May Reduce COVID - 19 Mortality
Odds of contracting COVID - 19, COVID - 19 - related mortality higher for individuals with diabetes (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - January 27, 2021 Category: Respiratory Medicine Tags: Endocrinology, Family Medicine, Geriatrics, Gynecology, Infections, Internal Medicine, Critical Care, Nursing, Pharmacy, Pulmonology, Journal, Source Type: news

Metformin Use for T2DM May Reduce COVID-19 Mortality
WEDNESDAY, Jan. 27, 2021 -- Diabetes is associated with increased odds of contracting COVID-19 and with increased COVID-19 mortality, while metformin treatment before diagnosis of COVID-19 is associated with reduced odds of related mortality,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 27, 2021 Category: Pharmaceuticals Source Type: news

Nostrum Laboratories, Inc. Expands Voluntary Nationwide Recall of Metformin HCl Extended Release Tablets, USP 750 mg, Due to N-Nitrosodimethylamine (NDMA) Content Above the Acceptable Daily Intake (ADI) Limit
Nostrum Laboratories, Inc. is voluntarily recalling one lot of Metformin HCl Extended Release Tablets, USP 750 mg (generic equivalent to Glucophage Tablets) to the consumer level. The Metformin HCl Extended Release Tablets, USP 750 mg (generic equivalent to Glucophage Tablets) have been found to con (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 25, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Metformin Treatment Again Linked to Fewer Deaths From COVID-19 Metformin Treatment Again Linked to Fewer Deaths From COVID-19
The latest of several studies, this time in a very diverse population, shows a striking threefold reduction in deaths from COVID-19 in those taking this leading treatment for type 2 diabetes.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - January 20, 2021 Category: Intensive Care Tags: Infectious Diseases News Source Type: news

Metformin Treatment Again Linked to Fewer Deaths From COVID-19 Metformin Treatment Again Linked to Fewer Deaths From COVID-19
The latest of several studies, this time in a very diverse population, shows a striking threefold reduction in deaths from COVID-19 in those taking this leading treatment for type 2 diabetes.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - January 20, 2021 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Metformin use reduces risk of death for patients with COVID-19 and diabetes
Use of the diabetes drug metformin - before a diagnosis of COVID-19 - is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham. Diabetes is a significant comorbidity for COVID-19. (Source: World Pharma News)
Source: World Pharma News - January 18, 2021 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Metformin use reduces risk of death for patients with COVID-19 and diabetes
(University of Alabama at Birmingham) Use of the diabetes drug metformin -- before a diagnosis of COVID-19 -- is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham. Diabetes is a significant comorbidity for COVID-19. This beneficial effect remained, even after correcting for age, sex, race, obesity, and hypertension or chronic kidney disease and heart failure. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 14, 2021 Category: Infectious Diseases Source Type: news

Granules gets American drug regulator's nod for diabetes management drug Metformin
The US Food and Drug Administration (USFDA) has granted final approval for the company's abbreviated new drug application (ANDA) for Metformin Hydrochloride extended-release tablets USP, 500 mg and 1000 mg, Granules said in a regulatory filing. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - January 13, 2021 Category: Pharmaceuticals Source Type: news

Another Lot of Extended-Release Metformin Is Recalled in the US Another Lot of Extended-Release Metformin Is Recalled in the US
Adding to two lots recalled in November, Nostrum Laboratories has issued a voluntary recall for another lot of extended-release metformin 750 mg due to possible contamination with NDMA.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - January 7, 2021 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

More Metformin Is Recalled
Another Lot of Extended-Release Metformin Is Recalled in the US (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 7, 2021 Category: General Medicine Source Type: news

Nostrum Laboratories, Inc. Expands Voluntary Nationwide Recall of Metformin HCl Extended Release Tablets, USP 750 mg, Due to N-Nitrosodimethylamine (NDMA) Content Above the Acceptable Daily Intake (ADI) Limit
Nostrum Laboratories, Inc. is voluntarily recalling one lot of Metformin HCl Extended Release Tablets, USP 750 mg (generic equivalent to Glucophage Tablets) to the consumer level. The Metformin HCl Extended Release Tablets, USP 750 mg (generic equivalent to Glucophage Tablets) have been found to con (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 5, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Can early drug intervention prevent weight gain in children with mental illness?
(University of Houston) A University of Houston pharmacological researcher believes that prescribing the drug Metformin for children and teens as soon as they are diagnosed with mental illnesses, like bipolar disorder and schizophrenia, may save them from gaining an enormous amount of weight. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - December 16, 2020 Category: International Medicine & Public Health Source Type: news

Metformin Use May Reduce Mortality in Women With COVID-19
WEDNESDAY, Dec. 9, 2020 -- For women with type 2 diabetes or obesity who are admitted to the hospital with COVID-19, metformin use is associated with significantly reduced mortality, according to a study published online Dec. 3 in The Lancet Healthy... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 9, 2020 Category: Pharmaceuticals Source Type: news

Pilot Study Looks at Metformin in COVID-19 Pilot Study Looks at Metformin in COVID-19
Small RCT will look at whether metformin has an impact on COVID-19, starting with inflammatory markers and viral load, but hoping to expand to outcomes.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - December 7, 2020 Category: Infectious Diseases Tags: Diabetes & Endocrinology News Source Type: news

New studies show diabetes drug not proven to improve blood sugar control in pediatric patients
The FDA has approved labeling changes stating that Januvia (sitagliptin), Janumet (sitagliptin and metformin hydrochloride), and Janumet XR (sitagliptin and metformin hydrochloride extended-release) are not proven to improve glycemic (blood sugar) control in pediatric patients. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 4, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Study finds metformin reduced COVID-19 death risks in women
University of Minnesota Medical School and UnitedHealth Group (NYSE: UNH) researchers found that metformin was associated with significantly reduced COVID-19 death risks in women in one of the world's largest observational studies of COVID-19 patients. Metformin is an established, generic medication for managing blood sugar levels in patients with type 2 diabetes. (Source: World Pharma News)
Source: World Pharma News - December 3, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Study finds metformin reduced COVID-19 death risks in women
(University of Minnesota Medical School) University of Minnesota Medical School and UnitedHealth Group researchers found that metformin was associated with significantly reduced COVID-19 death risks in women in one of the world's largest observational studies of COVID-19 patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 3, 2020 Category: International Medicine & Public Health Source Type: news

Study: Taking common drugs linked to impaired microbiome health and increased risk of obesity and intestinal infections
(Natural News) Researchers from the University Medical Center Groningen and Maastricht University Medical Center in the Netherlands have found that 18 common drug categories can negatively impact the gut microbiome, the total population of microbes present in the gut and their collective genetic material. Many of these drugs, such as the diabetes drug metformin and the antidepressant selective... (Source: NaturalNews.com)
Source: NaturalNews.com - November 25, 2020 Category: Consumer Health News Source Type: news

Metformin Improves Most Outcomes for T2D During Pregnancy Metformin Improves Most Outcomes for T2D During Pregnancy
Women with type 2 diabetes require fewer insulin doses and have a lower birthweight baby if they take metformin during pregnancy, one of the first randomized controlled trials to assess this shows.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - November 20, 2020 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

Metformin for Diabetes During Pregnancy
Metformin Improves Most Outcomes for Diabetes During Pregnancy (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 20, 2020 Category: General Medicine Source Type: news

Some Types of Metformin Recalled Due to Cancer Risk
Experts explain the back-and-forth on this popular diabetes drug ... If you take metformin to help manage diabetes, take note: Despite recent warnings and partial recalls by the Food and Drug Admin... (Source: AARP.org News)
Source: AARP.org News - November 16, 2020 Category: American Health Source Type: news

Nostrum Laboratories, Inc. Issues Voluntary Nationwide Recall of Metformin HCl Extended Release Tablets, USP 500 mg, Due to N-Nitrosodimethylamine (NDMA) Content Above the Acceptable Daily Intake (ADI) Limit
Nostrum Laboratories, Inc. is voluntarily recalling 2 (two) lots of Metformin HCl Extended Release Tablets, USP 500 mg to the consumer level. The Metformin HCl Extended Release Tablets, USP 500 mg have been found to contain levels of nitrosamine impurities above the ADI limit of 96 ng/day as publish (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - November 3, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Nostrum Laboratories, Inc. Issues Voluntary Nationwide Recall of Metformin HCl Extended Release Tablets, USP 750 mg, Due to N-Nitrosodimethylamine (NDMA) Content Above the Acceptable Daily Intake (ADI) Limit
Kansas City, Missouri, Nostrum Laboratories, Inc. is voluntarily recalling 2 (two) lots of Metformin HCl Extended Release Tablets, USP 750 mg to the consumer level. The Metformin HCl Extended Release Tablets, USP 750 mg have been found to contain levels of nitrosamine impurities above the ADI limit (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - November 2, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Use of Common Meds Tied to Lower Lung Cancer Mortality
Combined use of aspirin, statins, metformin tied to lower lung cancer risk and mortality (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - October 17, 2020 Category: Respiratory Medicine Tags: Cardiology, Endocrinology, Family Medicine, Internal Medicine, Oncology, Pharmacy, Pulmonology, Journal, Source Type: news

Use of Common Meds Tied to Lower Lung Cancer Mortality
FRIDAY, Oct. 16, 2020 -- Use of aspirin, metformin, and statins is associated with a lower risk for lung cancer mortality, according to a study published online Sept. 17 in the Journal of Thoracic Oncology. Jihun Kang, M.D., from Kosin University... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 16, 2020 Category: Pharmaceuticals Source Type: news

Hidradenitis Suppurativa Therapy Options Should Be Patient Guided Hidradenitis Suppurativa Therapy Options Should Be Patient Guided
A modern approach to hidradenitis suppurativa that incorporates such strategies as lasers, marsupialization, and metformin is built on a strategy individualized to the patient's most challenging symptoms.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 13, 2020 Category: Consumer Health News Tags: Dermatology News Source Type: news

Recall Widens for Diabetes Drug Metformin Recall Widens for Diabetes Drug Metformin
More than 175 different drug combinations have been recalled since late May.WebMD Health News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 13, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Recall Widens for Diabetes Drug Metformin
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 13, 2020 Category: General Medicine Source Type: news

Sun Pharma recalls 747 bottles of generic diabetes drug from the American market
As per the latest Enforcement Report of the US Food and Drug Administration (USFDA), Sun Pharmaceutical Industries is recalling the bottles of RIOMET ER (metformin hydrochloride for extended-release oral suspension) in the American market. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - October 11, 2020 Category: Pharmaceuticals Source Type: news

'Don't panic.' Anti-diabetes medication recalled, may contain high levels of cancer-causing compound
Marksans Pharma and Sun Pharmaceutical Industries recalled metformin this week due to high levels of a cancer-causing compound,... (Source: Reuters: Health)
Source: Reuters: Health - October 9, 2020 Category: Consumer Health News Source Type: news

Widely Used Diabetes Drug Recalled For High Levels Of Cancer-Causing Agent
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 9, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN Diabetes Recall Source Type: news