How An Old Diabetes Drug Made A Big Splash At The Biggest Cancer Confab
Metformin has been used for the last two decades to lower blood sugar in patients with type 2 diabetes. But the drug may find a second life in cancer care. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 7, 2018 Category: Pharmaceuticals Authors: Arlene Weintraub, Contributor Source Type: news

Metformin safe for most diabetics with kidney disease
Metform, a longtime and low-cost drug used to treat diabetes, is safe for most patients who also have chronic kidney disease, according to new research. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 5, 2018 Category: Consumer Health News Source Type: news

Evidence Growing Metformin Safe in Many With Diabetes and CKD Evidence Growing Metformin Safe in Many With Diabetes and CKD
Rates of acidosis comparable in metformin-treated and nontreated patients with type 2 diabetes and mild to moderate chronic kidney disease when eGFR is at least 30 mL/min/1.73 m2.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 5, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Metformin therapy safe in chronic kidney disease patients
In patients with mild, moderate chronic kidney disease, the use of metformin does not increase lactic acidosis, according to a study inJAMA Internal Medicine.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - June 5, 2018 Category: Endocrinology Source Type: news

Common diabetes drug found safe for most diabetics with kidney disease
(Johns Hopkins Medicine) Results of a large-scale study suggest that the oral diabetes drug metformin is safe for most diabetics who also have chronic kidney disease (CKD). The study of more than 150,000 adults by Johns Hopkins Medicine investigators found that metformin's association with the development of a life-threatening condition called lactic acidosis was seen only among patients with severely decreased kidney function. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 5, 2018 Category: International Medicine & Public Health Source Type: news

Computer simulations identify chemical key to diabetes drug alternatives
(University of Tennessee at Knoxville) Jeremy Smith, Governor's Chair for Molecular Biophysics at the University of Tennessee, Knoxville, and director of the Center for Molecular Biophysics at Oak Ridge National Laboratory, has worked with a research team from the UT Health Science Center to discover a chemical compound that could lower sugar levels as effectively as the diabetes drug metformin but with a lower dose. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 5, 2018 Category: International Medicine & Public Health Source Type: news

Metformin could ‘help millions with heart and circulatory disease’
Metformin – the cheap drug routinely used for the treatment of type 2 diabetes – could also help millions of other patients with cardiovascular conditions in the UK, according to researchers. (Source: Nursing Times)
Source: Nursing Times - June 4, 2018 Category: Nursing Source Type: news

A cheap 1p diabetes pill can stop heart attacks and strokes
Two British studies found that those taking the drug metformin – which costs as little as 1p a pill – had lower blood pressure, lost weight and saw harmful thickening of the heart reversed. (Source: the Mail online | Health)
Source: the Mail online | Health - June 4, 2018 Category: Consumer Health News Source Type: news

Metformin Reduces Mild Statin-Induced Myalgia
Risk of non-severe statin muscle pain reduced in T2DM patients taking both metformin and statins, according to this recent study.   (Source: ConsultantLive)
Source: ConsultantLive - May 15, 2018 Category: Internal Medicine Authors: Gregory M. Weiss, MD Source Type: news

Diabetes: Is THIS drug hiding a deadly secret?
EVERY year, 20 million prescriptions are written for metformin, a glucose-lowering medicine taken by 90 per cent of the three million Britons diagnosed with Type 2 diabetes. (Source: Daily Express - Health)
Source: Daily Express - Health - May 15, 2018 Category: Consumer Health News Source Type: news

Menstrual Dysfunction Common in Youth-Onset T2D (CME/CE)
(MedPage Today) -- PCOS may also be present, but masked by metformin treatment (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 25, 2018 Category: Cardiology Source Type: news

Two New Drug Classes Tied to Better Survival in Type 2 Diabetes Two New Drug Classes Tied to Better Survival in Type 2 Diabetes
Based on a network meta-analysis, SGLT-2 inhibitors and GLP-1 agonists may be preferred over DPP-4 inhibitors as add-on therapies to metformin for type 2 diabetes, researchers report.Medscape Medical News (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - April 18, 2018 Category: Primary Care Tags: Diabetes & Endocrinology News Source Type: news

Most widely prescribed diabetes drug improves nicotine withdrawal symptoms in animal model
(University of Pennsylvania School of Medicine) Metformin, the most widely used medication for diabetes, has also been shown to help treat dementia and some cancers. New research shows smoking cessation may be added to that list. The research team found that after giving mice metformin the animals displayed reduced symptoms when going through nicotine withdrawal. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 12, 2018 Category: International Medicine & Public Health Source Type: news

My T2DM Patient is Not at Goal with Metformin . . . What ’s Next?
A 52-year-old woman with T2DM is on metformin, works with a dietitian, and excercises regularly, but her hemoglobin A1c has increased. What would you advise?   (Source: ConsultantLive)
Source: ConsultantLive - April 10, 2018 Category: Internal Medicine Authors: Edward C. Chao Tags: Diabetes T2 Diabetes Source Type: news

Type 2 diabetes drug Metformin may help treat nicotine withdrawal
Researchers at Johns Hopkins University found that metformin, a drug used to treat type 2 diabetes, could prevent symptoms of nicotine withdrawal, such as cravings and fatigue. (Source: the Mail online | Health)
Source: the Mail online | Health - April 5, 2018 Category: Consumer Health News Source Type: news

Study: Diabetes drug metformin may help with nicotine withdrawal
Metformin, besides commonly treating people with type 2 diabetes, might help curb nicotine withdrawal without side effects, according to a study of mice. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 5, 2018 Category: Consumer Health News Source Type: news

Herbal and fruit supplement found to be more effective at managing diabetes than metformin drug
(Natural News) Type 2 diabetes can be a tricky illness to manage. In many cases, it is entirely possible to keep it under control with proper diet and regular exercise, and the lack of side effects makes this the most prudent approach for many people. However, others turn to diabetes drugs like Metformin to manage... (Source: NaturalNews.com)
Source: NaturalNews.com - April 2, 2018 Category: Consumer Health News Source Type: news

Use of most-prescribed diabetes drug, metformin, during pregnancy found to increase risk of obesity in the child
(Natural News) According to the results of a study, women who take metformin, a common diabetes medication, could be putting their children at increased risk of being obese or overweight. More pregnant women with gestational diabetes or polycystic ovary syndrome (PCOS) are taking metformin to treat their conditions. PCOS usually causes infertility, and the condition can put... (Source: NaturalNews.com)
Source: NaturalNews.com - March 26, 2018 Category: Consumer Health News Source Type: news

Metformin May Prevent Pregnancy Complications in PCOS Metformin May Prevent Pregnancy Complications in PCOS
In women with polycystic ovary syndrome, metformin treatment during pregnancy cut the risks for late miscarriage and preterm birth, but didn't prevent gestational diabetes.Medscape Medical News (Source: Medscape ObGyn and Womens Health Headlines)
Source: Medscape ObGyn and Womens Health Headlines - March 22, 2018 Category: OBGYN Tags: Diabetes & Endocrinology News Source Type: news

Metformin use may lower pregnancy complications in PCOS
New research presented at ENDO 2018 suggests that women who suffer from PCOS, and use metformin during pregnancy, are at a lower risk of late miscarriage and premature birth.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 21, 2018 Category: Endocrinology Source Type: news

Metformin, Statins Not Linked With Ovarian Cancer Risk in Diabetic Patients
A large study found no association between the use of metformin or statins and the incidence of ovarian cancer in women with type 2 diabetes. (Source: CancerNetwork)
Source: CancerNetwork - March 16, 2018 Category: Cancer & Oncology Authors: Dave Levitan Tags: Gynecologic Cancers News Ovarian Cancer Source Type: news

Medical News Today: How an existing diabetes drug controls pancreatic cancer
A new study suggests that targeting the RET signaling pathway with metformin might offer a new way to stop the growth and spread of pancreatic cancer. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 15, 2018 Category: Consumer Health News Tags: Pancreatic Cancer Source Type: news

NIH-funded study: Early, intensive treatment may be needed for some youth with type 2 diabetes
Inability of youth with type 2 diabetes to get blood glucose levels into a nondiabetic range shortly after using metformin alone may be due to genetics. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

New Mechanism Proposed for Glucose-lowering Effect of Metformin, a Drug for Type 2 Diabetes
Evidence that metformin tampers with glucagon-induced glucose output by disrupting glucagon signaling in liver cells may lead to new type 2 diabetes treatments. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Metformin use during pregnancy linked to heavier babies
A study in theJournal of Clinical Endocrinology& Metabolism reports that PCOS patients who take metformin during pregnancy are more likely to have heavier babies.Medpage Today (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 28, 2018 Category: Endocrinology Source Type: news

Metformin in Pregnancy Tied to Heavier Toddlers
(MedPage Today) -- Effect seen in mothers with PCOS, gestational diabetes (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - February 27, 2018 Category: Endocrinology Source Type: news

Norwegian study reveals metformin can make children fat
Children whose mothers used metformin during pregnancy weighed more when they turned four, by around 1lb 12oz (0.8kg), Norwegian University of Science and Technology in Trondheim experts found. (Source: the Mail online | Health)
Source: the Mail online | Health - February 27, 2018 Category: Consumer Health News Source Type: news

Metformin in Pregnancy May Increase Childhood Obesity Risk Metformin in Pregnancy May Increase Childhood Obesity Risk
Women with polycystic ovary syndrome who take metformin during pregnancy appear to be more likely to have children who are overweight or obese, a follow-up of two Norwegian trials suggests.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 27, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

No Link Found for Metformin or Statins and Ovarian Cancer
Findings based on a Finnish study involving a national cohort of women with type 2 diabetes (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 27, 2018 Category: Cancer & Oncology Tags: Cardiology, Endocrinology, Family Medicine, Gynecology, Internal Medicine, Nursing, Oncology, Pharmacy, Journal, Source Type: news

Clinical and laboratory features of metformin intoxication in suicidal patients attending an intensive care unit - Cetinkaya A, Avci D, Erden A, Akca O, Ozer O, Kalan U, Gunal AI.
This study has been performed for the purpose of researching the complications occurred at patients who took metformin overdose in an attempt to suicide. None of the patients has the diagnosis of diabetes mellitus and never used metformin. ... (Source: SafetyLit)
Source: SafetyLit - February 26, 2018 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Prandimet (Repaglinide and Metformin HCl Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 12, 2018 Category: Drugs & Pharmacology Source Type: news

Novo Nordisk ’ s once-weekly Type II diabetes med approved in Europe
The European Commission has approved Novo Nordisk‘s (NYSE:NVO) once-weekly semaglutide drug, Ozempic, as a treatment for adults with Type II diabetes. The GLP-1 analogue’s label in Europe recommends that the drug is given when metformin is contraindicated or not tolerated, Novo Nordisk reported today. Get the full story at our sister site, Drug Delivery Business News. The post Novo Nordisk’s once-weekly Type II diabetes med approved in Europe appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - February 9, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Drug-Device Combinations Pharmaceuticals Regulatory/Compliance Wall Street Beat Novo Nordisk Source Type: news

Medical News Today: Does metformin help you lose weight?
We examine what impact metformin might have on weight loss, how this drug is used to treat diabetes, and whether or not it helps people to lose weight. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 27, 2018 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

What Comes After Metformin in Type 2 Diabetes? What Comes After Metformin in Type 2 Diabetes?
Choosing the right drug for the right patient can affect glycemic control and mortality outcomes.Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 26, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Viewpoint Source Type: news

Long-term Metformin in PCOS Benefits Women of All Weights Long-term Metformin in PCOS Benefits Women of All Weights
Long-term metformin given to women with PCOS improved menstrual cycle regularity and hormone profiles in normal and overweight women; however, there were differences in response by testosterone status.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 23, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

A Patient's Journey: Taming the Glucose Monster
(MedPage Today) -- Dramatic success with metformin, diet, and microbiome tweaks (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - January 12, 2018 Category: Endocrinology Source Type: news

TOO TOXIC to swallow: Up to a third of diabetics don't take their pills because of the debilitating side effects
(Natural News) According to a group of researchers, at least a third of diabetics do not take their medication due to fear of possible side effects. Diabetics in the U.K. are often prescribed metformin, the most commonly prescribed drug for type 2 diabetes. While there is no definite data on how many of the 3.4 million... (Source: NaturalNews.com)
Source: NaturalNews.com - January 5, 2018 Category: Consumer Health News Source Type: news

Metformin vs. Glucovance
Title: Metformin vs. GlucovanceCategory: MedicationsCreated: 1/5/2018 12:00:00 AMLast Editorial Review: 1/5/2018 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - January 5, 2018 Category: Endocrinology Source Type: news

Metformin Tied to Worse Pregnancy Outcomes, Diabetes Likely Culprit Metformin Tied to Worse Pregnancy Outcomes, Diabetes Likely Culprit
Women with pregestational diabetes who are taking metformin are at increased risk for poor pregnancy outcomes, new findings show.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 4, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Segluromet (Ertugliflozin and Metformin Hydrochloride Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 28, 2017 Category: Drugs & Pharmacology Source Type: news

FDA Approves Segluromet (ertugliflozin and metformin hydrochloride) for Type 2 Diabetes
KENILWORTH, N.J.& NEW YORK--(BUSINESS WIRE) December 22, 2017 --Merck (NYSE:MRK), known as MSD outside the United States and Canada, and Pfizer Inc. (NYSE:PFE), today announced that the U.S. Food and Drug Administration (FDA) has approved... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - December 22, 2017 Category: Drugs & Pharmacology Source Type: news

Three in 10 Doses of Metformin Not Taken by Patients With T2D Three in 10 Doses of Metformin Not Taken by Patients With T2D
Patients with type 2 diabetes (T2D) are less likely to take the most commonly prescribed diabetes drug, metformin, than other, newer medications, say UK researchers, who suggest adverse events may be to blame.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 22, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Metformin use found safe during pregnancy
Pregnant women taking metformin to treat conditions such as PCOS do not show an increase in adverse pregnancy outcomes, according to research in the BritishJournal of Clinical Pharmacology.Medpage Today (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 22, 2017 Category: Endocrinology Source Type: news

Metformin Found Safe in Pregnant Women With Diabetes (CME/CE)
(MedPage Today) -- Adverse outcomes tied to diabetes, not the drug (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 21, 2017 Category: Cardiology Source Type: news

Diabetes, but not diabetes drug, linked to poor pregnancy outcomes
(Wiley) New research indicates that pregnant women with pre-gestational diabetes who take metformin are at a higher risk for adverse pregnancy outcomes -- such as major birth defects and pregnancy loss -- than the general population, but their increased risk is not due to metformin but diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 20, 2017 Category: International Medicine & Public Health Source Type: news

Study: Most commonly-prescribed diabetes drug linked to lowest rate of compliance
Patients who take the most-commonly prescribed diabetes medication, metformin, are the least likely to adhere to a prescribed regimen, according to a study published in the journal Diabetes, Obesity and Metabolism. Researchers from the University of Surrey looked at data from 1.6 million people with Type II diabetes across 48 trials and found that 30% of metformin doses prescribed to patients are not taken, compared to 23% for sulfonylureas and 20% for pioglitazone. Get the full story at our sister site, Drug Delivery Business News. The post Study: Most commonly-prescribed diabetes drug linked to lowest rate of compli...
Source: Mass Device - December 18, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Pharmaceuticals Research & Development Eli Lilly & Co. Novo Nordisk Sanofi-Aventis Source Type: news

One in three diabetic patients not taking drugs for fear of side effects
A study inDiabetes, Obesity and Metabolism reports that a third of diabetic patients are not taking metformin, and researchers hypothesise it may be due to the side effects of the drug.Daily Mail (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 18, 2017 Category: Endocrinology Source Type: news

Up to a third of diabetics won't take their pills
For many people, taking the Metformin pill is an essential - yet University of Surrey researchers found 30 per cent of prescribed doses are never taken. (Source: the Mail online | Health)
Source: the Mail online | Health - December 18, 2017 Category: Consumer Health News Source Type: news

Third of people not taking their prescribed diabetes medication due to side effects
(University of Surrey) Diabetes patients who take the most commonly prescribed diabetes drug, metformin, are the least likely to follow medical advice regarding their medication due its side effects, a new article in the journal Diabetes, Obesity and Metabolism reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 17, 2017 Category: International Medicine & Public Health Source Type: news

Mother ’ s Weight May Affect Metformin's Influence on Fetal Growth Mother ’ s Weight May Affect Metformin's Influence on Fetal Growth
Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 12, 2017 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news