Janssen Announces Unblinding of Phase 3 CARTITUDE-4 Study of CARVYKTI ® (cilta-cel) as Primary Endpoint Met in Treatment of Patients with Relapsed and Refractory Multiple Myeloma
RARITAN, New Jersey, January 27, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Phase 3 CARTITUDE-4 study evaluating CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) versus pomalidomide, bortezomib, and dexamethasone (PVd) or daratumumab, pomalidomide, and dexamethasone (DPd) for the treatment of patients with relapsed and lenalidomide-refractory multiple myeloma met its primary endpoint of significant improvement in progression-free survival (PFS) at the first pre-specified interim analysis. As a result of meeting the primary endpoint, the Independent Data Monitoring Commi...
Source: Johnson and Johnson - January 27, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

3 takeaways from this year ’s weird cold-and-flu-and-Covid season
Bita Honarvar/Vox; H. Armstrong Roberts/Classicstock/Getty Images Believe it or not, we are not going to be sick forever. The triple threat of influenza, respiratory syncytial virus (or RSV), and Covid-19 has been another stress test for a battered US health care system this winter. But after a…#rsv #cdc #davidcelantano #johnshopkins #newyorktimess #monicagandhi #xbb15 #ameshadalja #johnhopkins #fda (Source: Reuters: Health)
Source: Reuters: Health - January 27, 2023 Category: Consumer Health News Source Type: news

Bivalent Vaccine Provides Added Protection Against BA.5, XBB/XBB.1.5
THURSDAY, Jan. 26, 2023 -- Bivalent vaccines seem to provide additional protection against symptomatic BA.5 and XBB/XBB.1.5 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron sublineages, according to research published in the Jan.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 26, 2023 Category: Pharmaceuticals Source Type: news

Pediatric SARS-CoV-2, MIS-C Differed in Delta, Omicron Waves
THURSDAY, Jan. 26, 2023 -- The clinical presentation of hospitalized children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive testing or multisystem inflammatory syndrome in children (MIS-C) differed in the delta and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 26, 2023 Category: Pharmaceuticals Source Type: news

Can Docs Stop Elder Abuse From the Exam Room? Can Docs Stop Elder Abuse From the Exam Room?
Older adults with dementia are much more likely to be victims of abuse at the hands of caregivers. Researchers are working on a tool to help physicians identify mistreatment during examinations.Medscape Medical News (Source: Medscape Pulmonary Medicine Headlines)
Source: Medscape Pulmonary Medicine Headlines - January 26, 2023 Category: Respiratory Medicine Tags: Family Medicine/Primary Care News Source Type: news

SARS-CoV-2 Antibody Responses to the Ancestral SARS-CoV-2 Strain and Omicron BA.1 and BA.4/BA.5 Variants in Nursing Home Residents After Receipt of Bivalent COVID-19 Vaccine - Ohio and Rhode Island, September-November 2022
This report describes a broadened antibody response among nursing home residents who received an updated COVID-19 vaccine. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 26, 2023 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Older Adults' Health SARS (Severe acute respiratory syndrome) Vaccination Vaccines COVID-19 Nursing Homes Assisted Living Facilities Source Type: news

Laboratory-Confirmed COVID-19 Case Incidence Rates Among Residents in Nursing Homes by Up-to-Date Vaccination Status - United States, October 10, 2022-January 8, 2023
This report describes lower weekly rates of COVID-19 among nursing home residents who are up to date with COVID-19 vaccination. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 26, 2023 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Older Adults' Health SARS (Severe acute respiratory syndrome) Vaccination Vaccines COVID-19 Nursing Homes Assisted Living Facilities Source Type: news

North Korea is under lockdown to fight the spread of a respiratory disease
Authorities have made no mention of COVID. North Korea claimed victory over the disease by August, but experts remain skeptical of that claim. The lockdown will last from Wednesday until Sunday. (Image credit: Kim Won Jin/AFP via Getty Images) (Source: NPR Health and Science)
Source: NPR Health and Science - January 26, 2023 Category: Consumer Health News Authors: Anthony Kuhn Source Type: news

Placental Lesions ID'd on Prenatal MRI After SARS-CoV-2 Infection
WEDNESDAY, Jan. 25, 2023 -- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy can lead to placental lesions, according to a study published online Jan. 20 in The Lancet Regional Health Europe. Patric Kienast, M.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 25, 2023 Category: Pharmaceuticals Source Type: news

EARLY RELEASE: Early Estimates of Bivalent mRNA Booster Dose Vaccine Effectiveness in Preventing Symptomatic SARS-CoV-2 Infection Attributable to Omicron BA.5- and XBB/XBB.1.5-Related Sublineages Among Immunocompetent Adults - Increasing Community Access to Testing Program, United States, December 2022-January 2023
This report describes how a bivalent mRNA booster dose provided additional protection against symptomatic XBB/XBB.1.5 infection for at least the first 3 months after vaccination in persons who had previously received 2-4 monovalent vaccine doses. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 25, 2023 Category: American Health Tags: Adult Health Coronavirus [CoV] MMWR Morbidity & Mortality Weekly Report SARS (Severe acute respiratory syndrome) Vaccination Vaccines COVID-19 Source Type: news

North Korea Locks Down Capital City Over'Respiratory Illness'North Korea Locks Down Capital City Over'Respiratory Illness '
Authorities in the North Korean capital Pyongyang have ordered a 5-day lockdown due to rising cases of an unspecified respiratory illness, the Russian embassy and Seoul-based NK News reported on Wednesday, citing a government notice.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 25, 2023 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Physical Activity Linked to Fewer Days of Cold Symptoms
(MedPage Today) -- Higher baseline levels of physical activity and participation in sports among young children were associated with fewer days of symptoms from upper respiratory tract infections (URTIs) such as the common cold, a cross-sectional... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 25, 2023 Category: Infectious Diseases Source Type: news

Pediatric Respiratory Failure No Better Off With Early High-Flow Oxygen
(MedPage Today) -- SAN FRANCISCO -- Starting high-flow oxygen right away for young children with acute hypoxemic respiratory failure didn't help them leave the hospital sooner than standard oxygen therapy, the PARIS-2 trial showed. In fact... (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - January 24, 2023 Category: Pediatrics Source Type: news

Johnson & Johnson Reports Q4 and Full-Year 2022 Results
NEW BRUNSWICK, N.J. – January 24, 2023 – Johnson & Johnson (NYSE: JNJ) today announced results for fourth-quarter and full year 2022. “Our full year 2022 results reflect the continued strength and stability of our three business segments, despite macroeconomic challenges,” said Joaquin Duato, Chairman of the Board and Chief Executive Officer. “I am inspired by our employees who make a difference in the health and lives of people around the world every day. As we look ahead to 2023, Johnson & Johnson is well-positioned to drive near-term growth, while also investing strategically to deliver long-term value...
Source: Johnson and Johnson - January 24, 2023 Category: Pharmaceuticals Source Type: news

Kids Who Exercise More Are Less Likely To Get Respiratory Infections, Study Suggests
Researchers gathered data from over 100 children between 2018 and 2019. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 24, 2023 Category: Pharmaceuticals Authors: Ty Roush, Forbes Staff Tags: Business /business Innovation /innovation Healthcare /healthcare Science /science Breaking breaking-news Source Type: news