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The effect of combining manual therapy with exercise for mild chronic obstructive pulmonary disease: study protocol for a randomised controlled trial
DiscussionThis randomised controlled trial is designed to investigate whether the combination of MT and exercise delivers any additional benefits to people with mild COPD compared to exercise alone. The study is designed in response to recommendations from a recent systematic review calling for more research into the effect of MT in the management of COPD.Trial registrationANZCTRN,12614000766617. Registered on 18 July 2014. (Source: Trials)
Source: Trials - June 17, 2017 Category: Research Source Type: clinical trials

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the GlaxoSmithKline (GSK) Biologicals' Respiratory Syncytial Virus (RSV) Investigational Vaccine (GSK3003891A) in Healthy Pregnant Women and Infants Born to Vaccinated Mothers
Condition:   Respiratory Syncytial Virus Infections Interventions:   Biological: RSV vaccine (GSK3003891A) formulation 1;   Biological: RSV vaccine (GSK3003891A) formulation 2;   Biological: RSV vaccine (GSK3003891A) formulation 3;   Drug: Placebo (Formulation buffer S9b) Sponsor:   GlaxoSmithKline Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2017 Category: Research Source Type: clinical trials

Efficacy and Safety Study of Ingavirin ® to Treat Influenza and Acute Respiratory Viral Infections in Children 7-12 y.o.
Conditions:   Influenza, Human;   Acute Respiratory Infection;   Viral Infection;   Common Cold Interventions:   Drug: Ingavirin;   Drug: Placebo oral capsule Sponsors:   Valenta Pharm JSC;   Atlant Clinical Ltd. Completed - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2017 Category: Research Source Type: clinical trials

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the GlaxoSmithKline (GSK) Biologicals' Respiratory Syncytial Virus (RSV) Investigational Vaccine (GSK3003891A) in Healthy Pregnant Women and Infants Born to Vaccinated Mothers
Condition:   Respiratory Syncytial Virus Infections Interventions:   Biological: RSV vaccine (GSK3003891A) formulation 1;   Biological: RSV vaccine (GSK3003891A) formulation 2;   Biological: RSV vaccine (GSK3003891A) formulation 3;   Drug: Placebo (Formulation buffer S9b) Sponsor:   GlaxoSmithKline Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2017 Category: Research Source Type: clinical trials

Efficacy and Safety Study of Ingavirin ® to Treat Influenza and Acute Respiratory Viral Infections in Children 7-12 y.o.
Conditions:   Influenza, Human;   Acute Respiratory Infection;   Viral Infection;   Common Cold Interventions:   Drug: Ingavirin;   Drug: Placebo oral capsule Sponsors:   Valenta Pharm JSC;   Atlant Clinical Ltd. Completed - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2017 Category: Research Source Type: clinical trials

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the GlaxoSmithKline (GSK) Biologicals' Respiratory Syncytial Virus (RSV) Investigational Vaccine (GSK3003891A) in Healthy Pregnant Women and Infants Born to Vaccinated Mothers
Condition:   Respiratory Syncytial Virus Infections Interventions:   Biological: RSV vaccine (GSK3003891A) formulation 1;   Biological: RSV vaccine (GSK3003891A) formulation 2;   Biological: RSV vaccine (GSK3003891A) formulation 3;   Drug: Placebo (Formulation buffer S9b) Sponsor:   GlaxoSmithKline Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2017 Category: Research Source Type: clinical trials

Efficacy and Safety Study of Ingavirin ® to Treat Influenza and Acute Respiratory Viral Infections in Children 7-12 y.o.
Conditions:   Influenza, Human;   Acute Respiratory Infection;   Viral Infection;   Common Cold Interventions:   Drug: Ingavirin;   Drug: Placebo oral capsule Sponsors:   Valenta Pharm JSC;   Atlant Clinical Ltd. Completed - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2017 Category: Research Source Type: clinical trials

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the GlaxoSmithKline (GSK) Biologicals' Respiratory Syncytial Virus (RSV) Investigational Vaccine (GSK3003891A) in Healthy Pregnant Women and Infants Born to Vaccinated Mothers
Condition:   Respiratory Syncytial Virus Infections Interventions:   Biological: RSV vaccine (GSK3003891A) formulation 1;   Biological: RSV vaccine (GSK3003891A) formulation 2;   Biological: RSV vaccine (GSK3003891A) formulation 3;   Drug: Placebo (Formulation buffer S9b) Sponsor:   GlaxoSmithKline Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2017 Category: Research Source Type: clinical trials

Effects of Respiratory Muscle Training on Respiratory Muscle Strength, Functional Capacity and Quality of Life in Pulmonary Hypertension
Condition:   Respiratory Muscle Strength Intervention:   Other: respiratory muscle training Sponsor:   Faculdade de Ciências Médicas da Santa Casa de São Paulo Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Respiratory Muscle Training in CF Patients
Conditions:   Cystic Fibrosis;   Respiratory Muscles Interventions:   Other: Endurance respiratory muscle training;   Other: Resistance inspiratory muscle training Sponsor:   University Hospital, Grenoble Recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Effects of Respiratory Muscle Training on Respiratory Muscle Strength, Functional Capacity and Quality of Life in Pulmonary Hypertension
Condition:   Respiratory Muscle Strength Intervention:   Other: respiratory muscle training Sponsor:   Faculdade de Ciências Médicas da Santa Casa de São Paulo Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Respiratory Muscle Training in CF Patients
Conditions:   Cystic Fibrosis;   Respiratory Muscles Interventions:   Other: Endurance respiratory muscle training;   Other: Resistance inspiratory muscle training Sponsor:   University Hospital, Grenoble Recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Effects of Respiratory Muscle Training on Respiratory Muscle Strength, Functional Capacity and Quality of Life in Pulmonary Hypertension
Condition:   Respiratory Muscle Strength Intervention:   Other: respiratory muscle training Sponsor:   Faculdade de Ciências Médicas da Santa Casa de São Paulo Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Respiratory Muscle Training in CF Patients
Conditions:   Cystic Fibrosis;   Respiratory Muscles Interventions:   Other: Endurance respiratory muscle training;   Other: Resistance inspiratory muscle training Sponsor:   University Hospital, Grenoble Recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Effects of Respiratory Muscle Training on Respiratory Muscle Strength, Functional Capacity and Quality of Life in Pulmonary Hypertension
Condition:   Respiratory Muscle Strength Intervention:   Other: respiratory muscle training Sponsor:   Faculdade de Ciências Médicas da Santa Casa de São Paulo Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Respiratory Muscle Training in CF Patients
Conditions:   Cystic Fibrosis;   Respiratory Muscles Interventions:   Other: Endurance respiratory muscle training;   Other: Resistance inspiratory muscle training Sponsor:   University Hospital, Grenoble Recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Effects of Respiratory Muscle Training on Respiratory Muscle Strength, Functional Capacity and Quality of Life in Pulmonary Hypertension
Condition:   Respiratory Muscle Strength Intervention:   Other: respiratory muscle training Sponsor:   Faculdade de Ciências Médicas da Santa Casa de São Paulo Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Respiratory Muscle Training in CF Patients
Conditions:   Cystic Fibrosis;   Respiratory Muscles Interventions:   Other: Endurance respiratory muscle training;   Other: Resistance inspiratory muscle training Sponsor:   University Hospital, Grenoble Recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Effects of Respiratory Muscle Training on Respiratory Muscle Strength, Functional Capacity and Quality of Life in Pulmonary Hypertension
Condition:   Respiratory Muscle Strength Intervention:   Other: respiratory muscle training Sponsor:   Faculdade de Ciências Médicas da Santa Casa de São Paulo Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2017 Category: Research Source Type: clinical trials

Study of Post-Exposure Ingavirin ® Prophylaxis of Influenza and Acute Respiratory Viral Infections
Conditions:   Influenza, Human;   Acute Respiratory Infection;   Common Cold;   Flu;   Viral Infection Interventions:   Drug: Ingavirin (Imidazolyl Ethanamide Pentandioic Acid);   Drug: Placebo oral capsule Sponsor:   Valenta Pharm JSC Completed - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 8, 2017 Category: Research Source Type: clinical trials

A multicentre, randomised intervention study of the Paediatric Early Warning Score: study protocol for a randomised controlled trial
This study demonstrates the safety and effectiveness of a new PEWS model and contributes to knowledge of hospitalised children ’s clinical deterioration.Trial registrationClinicalTrials.gov,NCT02433327. Registered on 27 April 2015. (Source: Trials)
Source: Trials - June 8, 2017 Category: Research Source Type: clinical trials

Different strategies for mechanical VENTilation during CardioPulmonary Bypass (CPBVENT 2014): study protocol for a randomized controlled trial
AbstractBackgroundThere is no consensus on which lung-protective strategies should be used in cardiac surgery patients. Sparse and small randomized clinical and animal trials suggest that maintaining mechanical ventilation during cardiopulmonary bypass is protective on the lungs. Unfortunately, such evidence is weak as it comes from surrogate and minor clinical endpoints mainly limited to elective coronary surgery. According to the available data in the academic literature, an unquestionable standardized strategy of lung protection during cardiopulmonary bypass cannot be recommended. The purpose of the CPBVENT study is to ...
Source: Trials - June 7, 2017 Category: Research Source Type: clinical trials

Impact of community-initiated Kangaroo Mother Care on survival of low birth weight infants: study protocol for a randomized controlled trial
AbstractBackgroundAround 70% neonatal deaths occur in low birth weight (LBW) babies. Globally, 15% of babies are born with LBW. Kangaroo Mother Care (KMC) appears to be an effective way to reduce mortality and morbidity among LBW babies. KMC comprises of early and continuous skin-to-skin contact between mother and baby as well as exclusive breastfeeding. Evidence derived from hospital-based studies shows that KMC results in a 40% relative reduction in mortality, a 58% relative reduction in the risk of nosocomial infections or sepsis, shorter hospital stay, and a lower risk of lower respiratory tract infections in babies with birth weight
Source: Trials - June 7, 2017 Category: Research Source Type: clinical trials

NAVA Versus BiPAP Non-Invasive Respiratory Support in Infants Following Congenital Heart Surgery
Condition:   Respiratory Failure Interventions:   Device: Neurally-Adusted Ventilatory Assist (NAVA);   Device: Biphasic Positive Airway Pressure Support (BiPAP) Sponsor:   Children's Hospitals and Clinics of Minnesota Recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 6, 2017 Category: Research Source Type: clinical trials

The Role of Sustained Inflation on Short Term Respiratory Outcomes in Term Infants
Conditions:   Respiratory Distress Syndrome, Newborn;   Transient Tachypnea of the Newborn;   Respiratory Morbidity Intervention:   Other: Sustained Inflation Sponsor:   Kanuni Sultan Suleyman Training and Research Hospital Recruiting - verified May 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 23, 2017 Category: Research Source Type: clinical trials

Effect of Acetazolamide on Cognition in Patients With Respiratory Disease at Altitude
Condition:   Chronic Obstructive Pulmonary Disease (COPD) Interventions:   Drug: ACETAZOLAMIDE oral capsule;   Drug: Placebo oral capsule Sponsors:   University of Zurich;   National Center of Cardiology and Internal Medicine, Kyrgyzstan Recruiting - verified May 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 23, 2017 Category: Research Source Type: clinical trials

The Role of Sustained Inflation on Short Term Respiratory Outcomes in Term Infants
Conditions:   Respiratory Distress Syndrome, Newborn;   Transient Tachypnea of the Newborn;   Respiratory Morbidity Intervention:   Other: Sustained Inflation Sponsor:   Kanuni Sultan Suleyman Training and Research Hospital Recruiting - verified May 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 23, 2017 Category: Research Source Type: clinical trials

Effect of Acetazolamide on Cognition in Patients With Respiratory Disease at Altitude
Condition:   Chronic Obstructive Pulmonary Disease (COPD) Interventions:   Drug: ACETAZOLAMIDE oral capsule;   Drug: Placebo oral capsule Sponsors:   University of Zurich;   National Center of Cardiology and Internal Medicine, Kyrgyzstan Recruiting - verified May 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 23, 2017 Category: Research Source Type: clinical trials

Effect of Acetazolamide on Right Ventricular Function During Exercise in Patients With Respiratory Disease at Altitude
Condition:   Chronic Obstructive Pulmonary Disease Interventions:   Drug: ACETAZOLAMIDE oral capsule;   Drug: Placebo oral capsule Sponsors:   University of Zurich;   National Center of Cardiology and Internal Medicine, Kyrgyzstan Recruiting - verified May 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 23, 2017 Category: Research Source Type: clinical trials