Study identifies how hantaviruses infect lung cells
(Albert Einstein College of Medicine) Hantaviruses cause severe and sometimes fatal respiratory infections, but how they infect lung cells has been a mystery. In today's issue of Nature, an international team including researchers at Albert Einstein College of Medicine reports that hantaviruses gain entry to lung cells by 'unlocking' a cell-surface receptor called protocadherin-1 (PCDH1). Deleting this receptor made lab animals highly resistant to infection. The findings show that targeting PCDH1 could be a useful strategy against deadly hantavirus pulmonary syndrome. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 21, 2018 Category: Infectious Diseases Source Type: news

USAMRIID scientists help identify key hantavirus receptor
(US Army Medical Research Institute of Infectious Diseases) A global team of investigators has identified a key protein involved in Hantavirus Pulmonary Syndrome (HPS), a serious and sometimes fatal respiratory disease, according to research published today in Nature. The cell-surface receptor protein protocadherin-1 (PCDH1), commonly associated with human asthma, is responsible for facilitating lung cell infection and triggering HPS. Discovery of the cellular receptor for hantaviruses allows for rational and logical drug and antibody design to prevent the virus from infecting lung tissue. (Source: EurekAlert! - Infectious...
Source: EurekAlert! - Infectious and Emerging Diseases - November 21, 2018 Category: Infectious Diseases Source Type: news

How low can we go? Nanopore detection of single flu viruses to control outbreaks
(Osaka University) Influenza is a highly contagious respiratory disease that may cause a serious outbreak at any time. Here, an Osaka University-led research team developed a new nanosensor to detect single flu virus particles in a variety of samples. The method is quick, simple, and does not require specific training or expertise. This could help clinicians and public health agencies to control nascent flu outbreaks. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2018 Category: International Medicine & Public Health Source Type: news

Diagnostics Are Helping Counter Antimicrobial Resistance, But More Work Is Needed
Antimicrobial resistance (AMR) threats to patient health are becoming more widely recognized and diagnostics manufacturers are making significant progress in combatting the overuse of antibiotics. There is still a lot of work to be done, however. A recent health scare for Rick Bright, Ph.D., director of the Biomedical Advanced Research and Development Authority (BARDA), HHS, the very agency working to combat emerging infectious diseases (EID) and other threats, highlights the lingering risks.  During the 10th Public Meeting of the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB...
Source: MDDI - November 20, 2018 Category: Medical Devices Authors: Daphne Allen Tags: IVD Source Type: news

Increased Risk for Oral Cancer With Exposure to High PM2.5
Taiwanese men exposed to PM2.5 ≥ 40.37 µ g/m ³ have increased risk for oral cancer (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 20, 2018 Category: Respiratory Medicine Tags: Oncology, ENT, Pathology, Pulmonology, Journal, Source Type: news

Performance of AI Dx Tools May Suffer Across Health Systems
Performance for a pneumonia detection tool fell when applied at outside health systems (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 20, 2018 Category: Respiratory Medicine Tags: Infections, Internal Medicine, Pathology, Pulmonology, Radiology, Journal, Source Type: news

Well : Breathing Through the Nose May Offer Unique Brain Benefits
Could nasal breathing be more helpful for our brains than breathing through the mouth? (Source: NYT Health)
Source: NYT Health - November 20, 2018 Category: Consumer Health News Authors: GRETCHEN REYNOLDS Tags: Smell (Olfaction) Intelligence and Intelligence Tests (IQ) Nose Respiratory System Brain Memory Source Type: news

Medtronic ’ s Q2 results top estimates despite profit slide
Medtronic (NYSE:MDT) today posted fiscal second-quarter numbers that topped the consensus forecast, despite a bottom-line slide of more than -44%, sending share prices up in pre-market trading. The Fridley, Minn.-based company put up profits of $1.12 billion, or 82¢ per share, on sales of $7.48 billion for the three months ended Oct. 26, amounting to a -44.4% profit decline on sales growth of 6.7% compared with fiscal Q2 2018. Adjusted to exclude one-time items, earnings per share were $1.21, 6¢ ahead of Wall Street, where analysts were looking for sales of $7.35 billion. “This was an outstanding quarter fo...
Source: Mass Device - November 20, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Featured MassDevice Earnings Roundup Wall Street Beat Source Type: news

Asthma in Children
Title: Asthma in ChildrenCategory: Diseases and ConditionsCreated: 1/31/2005 12:00:00 AMLast Editorial Review: 11/20/2018 12:00:00 AM (Source: MedicineNet Asthma General)
Source: MedicineNet Asthma General - November 20, 2018 Category: Respiratory Medicine Source Type: news

Prevalence of Asthma, Rhinitis and Respiratory Symptoms Prevalence of Asthma, Rhinitis and Respiratory Symptoms
Which factors may be implicated in the changes in prevalence noted for respiratory disorders and symptoms over a 20-year period?BMC Pulmonary Medicine (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - November 20, 2018 Category: Allergy & Immunology Tags: Pulmonary Medicine Journal Article Source Type: news

Middle East respiratory syndrome coronavirus (MERS-CoV) – Saudi Arabia
From 16 through 30 October 2018, the International Health Regulations (IHR 2005) National Focal Point of Saudi Arabia reported four additional cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, including one death. (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - November 20, 2018 Category: Infectious Diseases Tags: news Source Type: news

11th Child Dies in Adenovirus Outbreak at N.J. Care Facility
MONDAY, Nov. 19, 2018 -- An 11th child has died in an outbreak of a respiratory virus at the Wanaque Center for Nursing and Rehabilitation in New Jersey, health officials say. The " severely ill child " had the adenovirus infection and died Thursday... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 19, 2018 Category: Pharmaceuticals Source Type: news

Philips wins CE Mark for V60 Plus high flow ventilator
Royal Philips (NYSE:PHG) said today it won CE Mark approval in the European Union for its Philips V60 Plus ventilator system. The Netherlands-based company said that the newly cleared system features both noninvasive ventilation and high flow therapy, which allows the system to be used with changing patient conditions without having to switch devices. The V60 is intended for early interventions into respiratory failure, Philips said, but is designed to deliver a wide range of non-invasive support for patients to lessen the challenge of weaning patients off of noninvasive ventilation. “When treating respiratory p...
Source: Mass Device - November 19, 2018 Category: Medical Devices Authors: Fink Densford Tags: Regulatory/Compliance Respiratory royalphilips Source Type: news

An Optimized, Large Scale Generation and Validation of Aspergillus-Specific T Lymphocytes for the Management of Invasive Aspergillosis in Immunocompromised Patients
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

A Ball of Fun: Allergic Bronchopulmonary Aspergillosis Presenting as a Pneumothorax
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Delayed Diagnosis of Cystic Fibrosis in a 62 Year Old Female Leading to Bilateral Lung Transplant
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Cystic Fibrosis Transmembrane Conductance Regulator ∆F508 Heterozygosity: A Spectrum of Disease Burden
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

3D Printing and the Cystic Fibrosis Lung
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Williams-Campbell Syndrome: An Elusive Cause of Bronchiectasis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Efficacy of Mucolytic Treatment in Decreasing Airway Resistance and Increasing Mucus Clearance in a Mouse Model of Allergic Asthma
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Oxidative Damage Abolishes the Ability of SP-D to Block Eosinophil Extracellular DNA Trap Release During Exacerbation of Allergic Airway Inflammation
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Necrotizing Sarcoid Granulomatosis Presenting as a Left Breast Mass Concerning for Malignancy
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Paradoxical Development of Panuveitis and Granulomatous Interstitial Lung Disease Associated with Adalimumab Therapy for Psoriasis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Philips Debuts Noninvasive Ventilator With High Flow Therapy to Improve Patient Care
Philips V60 Plus ventilator receives CE Mark, expands on Philips' commitment and leadership in hospital respiratory care New comprehensive solution enhances clinician workflow and maximizes equipment efficiency to help drive earlier intervention in resp... Devices, Regulatory, Product Launch Royal Philips, V60 Plus ventilator, noninvasive ventilation, respiratory failure (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 19, 2018 Category: Pharmaceuticals Source Type: news

Analysis on the Correlation of Fungus Extracts Allergen and the Components of Aspergillus Fumigatus sIgE Sensitization in Respiratory Allergic Diseases Patients in Southern China
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Health Highlights: Nov. 19, 2018
Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: 11th Child Dies in Respiratory Virus Outbreak at N.J. Care Facility An 11th child has died in an outbreak of a respiratory virus at the Wanaque... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 19, 2018 Category: General Medicine Source Type: news

Vapers May Prompt Smokers to Quit: Study
Title: Vapers May Prompt Smokers to Quit: StudyCategory: Health NewsCreated: 11/16/2018 12:00:00 AMLast Editorial Review: 11/19/2018 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - November 19, 2018 Category: Respiratory Medicine Source Type: news

What is the Recurrence Rate for Guillian-Barr é Syndrome and Should She Get An Influenza Vaccine?
Discussion Guillian-Barré syndrome (GBS) is an acquired, acute, inflammatory, demyelinating polyneuropathy. It is the most common cause of acute and subacute flaccid paralysis in children. GBS causes about 0.4-1.3 cases per 100,000 persons/year in children. It can occur in any age group and the incidence increases among all age groups until a peak in the 50s. Both genders are affected and there may be a slight increase in males. GBS usually occurs 2-4 weeks after a prodromal gastroenteritis or respiratory illness. GBS causes autoantibody production against Schwann cells of the neuron and the axon itself. There is ...
Source: PediatricEducation.org - November 19, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Study links autistic children back to mothers who had chronic respiratory ailments, inflammation during pregnancy
(Natural News) Clinical trials have shown an association between the autism spectrum disorder (ASD) and maternal immune activation (MIA), an active immune response after an infectious exposure during pregnancy, but this study is the first one to examine its link to an increase in behavioral abnormalities in children. The connection between ASD and MIA is... (Source: NaturalNews.com)
Source: NaturalNews.com - November 18, 2018 Category: Consumer Health News Source Type: news

Researchers a step closer to understanding how deadly bird flu virus takes hold in humans
(Griffith University) New research has taken a step towards understanding how highly pathogenic influenza viruses such as deadly bird flu infect humans. Researchers at Griffith's Institute for Glycomics and the University of Hong Kong have revealed specific sugar molecules -- Sialylated O-glycans -- that are present in the respiratory tract are key receptors for influenza viruses, particularly the highly pathogenic influenza virus strains. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 18, 2018 Category: Infectious Diseases Source Type: news

Aurobindo Pharma to launch oncology, respiratory products in US by 2021
The company is also focussing on securing intellectual property (IP) and ramping up and filing of specialty products. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 18, 2018 Category: Pharmaceuticals Source Type: news

Air Quality in California: Devastating Fires Lead to a New Danger
A week after the most destructive fire in state history ripped through this small town, the flames have been replaced by a new danger: the air. (Source: NYT Health)
Source: NYT Health - November 17, 2018 Category: Consumer Health News Authors: JULIE TURKEWITZ and MATT RICHTEL Tags: Fires and Firefighters Hazardous and Toxic Substances Immune System Wildfires Respiratory System California Source Type: news

The multiple hit hypothesis for Gulf War illness: self-reported chemical/biological weapons exposure and mild traumatic brain injury - Janulewicz P, Krengel M, Quinn E, Heeren T, Toomey R, Killiany R, Zundel C, Ajama J, O'Callaghan J, Steele L, Klimas N, Sullivan K.
The Gulf War Illness Consortium (GWIC) was designed to identify objective biomarkers of Gulf War Illness (GWI) in 1991 Gulf War veterans. The symptoms of GWI include fatigue, pain, cognitive problems, gastrointestinal, respiratory, and skin problems. Neuro... (Source: SafetyLit)
Source: SafetyLit - November 17, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

New inhibitor which blocks inflammation could also treat sepsis
(University of Sheffield) Scientists from the University of Sheffield have discovered a new inhibitor which decreases lung inflammation and could hold the key to treating Acute Respiratory Distress Syndrome -- a life-threatening disease which affects thousands of people in the UK. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 17, 2018 Category: Infectious Diseases Source Type: news

Air Quality in California: Devastating Fire Leads to a New Danger
A week after the most destructive fire in state history ripped through this small town, the flames have been replaced by a new danger: the air. (Source: NYT Health)
Source: NYT Health - November 16, 2018 Category: Consumer Health News Authors: JULIE TURKEWITZ and MATT RICHTEL Tags: Fires and Firefighters Hazardous and Toxic Substances Immune System Wildfires Respiratory System California Source Type: news

Vapotherm closes $64m IPO
Vapotherm said today it closed its initial public offering, raising a total $64.4 million in gross proceeds. The Exeter, N.H.-based company developed the Precision Flow line of devices to provide high-velocity heated, humidified and oxygenated air to treat patients with conditions such as pneumonia, chronic obstructive pulmonary disease, asthma and heart failure. Some 1,200 of the devices have been sold in the U.S., mostly into hospital ICUs, the company said. Vapotherm said it floated 4.6 million shares of its common stock at $14 per share, and that the offering featured a fully exercised underwriter’s option to pur...
Source: Mass Device - November 16, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Initial Public Offering (IPO) Respiratory Wall Street Beat Vapotherm Source Type: news

Patients Hospitalized for COPD Rarely Receive Pulmonary Rehab
Elderly, those living>10 miles from facility, those with lower SES less likely to receive pulmonary rehab (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 16, 2018 Category: Respiratory Medicine Tags: Internal Medicine, Nursing, Pulmonology, Geriatrics, Journal, Source Type: news

ACAAI: Hospital Stay, Caregiver Knowledge of Asthma Linked
Children of caregivers with poor asthma knowledge more likely to have prolonged hospital stay (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 16, 2018 Category: Respiratory Medicine Tags: Family Medicine, Nursing, Pediatrics, Pulmonology, Allergy, Emergency Medicine, Conference News, Source Type: news

Smoke Spreading From California Fires Sparks Health Concerns
Smoke masks. Eye drops. No outdoor exercise. This is how Californians are trying to cope with wildfires choking the state, but experts say an increase in serious health problems may be almost inevitable for vulnerable residents as the disasters become more commonplace. Research suggests children, the elderly and those with existing health problems are most at risk. Short-term exposure to wildfire smoke can worsen existing asthma and lung disease, leading to emergency room treatment or hospitalization, studies have shown. Increases in doctor visits or hospital treatment for respiratory infections, bronchitis and pneumonia i...
Source: JEMS: Journal of Emergency Medical Services News - November 16, 2018 Category: Emergency Medicine Authors: Lindsey Tanner, AP Medical Writer Tags: Patient Care News Source Type: news

Smoke Spreading From California Fires Sparks Health Concerns
Smoke masks. Eye drops. No outdoor exercise. This is how Californians are trying to cope with wildfires choking the state, but experts say an increase in serious health problems may be almost inevitable for vulnerable residents as the disasters become more commonplace. Research suggests children, the elderly and those with existing health problems are most at risk. Short-term exposure to wildfire smoke can worsen existing asthma and lung disease, leading to emergency room treatment or hospitalization, studies have shown. Increases in doctor visits or hospital treatment for respiratory infections, bronchitis and pneumonia i...
Source: JEMS Patient Care - November 16, 2018 Category: Emergency Medicine Authors: Lindsey Tanner, AP Medical Writer Tags: Patient Care News Source Type: news

GE divests $1.5B in healthcare equipment loan portfolio to TIAA Bank
General Electric (NYSE:GE) has divested a portfolio of its healthcare equipment leases and loans from its GE Capital Healthcare Equipment Finance biz to TIAA Bank in a $1.5 billion deal as GE looks to trim down and narrow its focus, the companies said today. Jacksonville, Fla.-based TIAA Bank said today that the acquisition will expand its commercial banking business and its ability to provide a full range of financial solutions to an increased number of healthcare providers. “This agreement with GE Capital supports our long-term asset growth plan and provides scale and portfolio diversification while significan...
Source: Mass Device - November 16, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Mergers & Acquisitions Wall Street Beat General Electric tiaabank Source Type: news

Chemosensitizers As Therapeutic Adjuncts in Allergic Airway Disease
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

A Health Literacy Readability Analysis of Online Allergy and Immunology-Based Patient Education Resources
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Comparison of Airborne Mold in the Mojave Desert and Las Vegas
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Diversity of Viable Airborne Fungi in Tulsa, Oklahoma
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Study on the Clinical and Immunological Characteristics of Fungal Sensitive Asthma and Allergic Bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

KCNJ2 overexpression induces pro-inflammatory cytokine production, impaired barrier function and acantholysis in esophageal epithelial cells
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Defining the Extent of Allergenic Cross-reactivity among Mold Species
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Clinical Findings of Patients with Autonomal Dominant Hyper IgE Syndrome (HIES) in Usidnet
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news