PSBJ Interview: Fred Hutch veteran Dr. Carla Grandori is flipping the script on cancer treatment
Grandori's company SEngine, is preparing for a future in which cancer is not going to be treated according to cancer type – like breast or colon – but it will be treated based on its genetic underpinning. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - February 16, 2019 Category: American Health Authors: Casey Coombs Source Type: news

Sorting Cancer-Associated Fibroblasts (CAFs)
Featuring Our Colorectal CAFSCAFs play a central role in the Tumor Microenvironment (TME). The TME has been identified as one of the driving factors of tumor progression and invasion. Inside this microenvironment, CAFs, a type of perpetually activated fibroblasts, have been implicated to have a strong tumor modulating effect and play a key role in areas such as drug resistance.This makes CAFs a target for cancer therapies. The challenge is the TME is heterogeneous making it a challenge to derive homogeneously relevant populations for basic research and drug discovery. This new study uses ourColorectal CAFs to identify...
Source: Neuromics - February 14, 2019 Category: Neuroscience Tags: CAFs Cancer Associated Fibroblasts CD90 colorectal CAFs Colorectal Cancer Flow cytometry PDGF Source Type: news

Check-Cap ’ s cancer screening capsule will have U.S. study
Check-Cap (NSDQ:CHEK) said its X-ray-enabled, colorectal cancer-screening capsule will have a pilot study in the United States. The Isfiya, Israel-based startup makes the C-Scan System, an ingestible capsule used to detect precancerous polyps without the need for laxatives or an invasive procedure. The C-Scan system uses an ultra-low dose X-ray capsule, an integrated positioning, control, and recording system, and proprietary software to generate a 3D map of the inner lining of the colon. It received approval from Israel’s Ministry of Health Medical Device division (AMAR) and the CE Mark...
Source: Mass Device - February 12, 2019 Category: Medical Devices Authors: Nancy Crotti Tags: Blog Clinical Trials Implants News Well Oncology Research & Development Check-Cap FDA New York University Source Type: news

Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take It
Low-dose aspirin can lower your risk for colon cancer but fewer than half the people who already have polyps aren’t taking it. (Source: WebMD Health)
Source: WebMD Health - February 12, 2019 Category: Consumer Health News Source Type: news

Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take It
Title: Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take ItCategory: Health NewsCreated: 2/11/2019 12:00:00 AMLast Editorial Review: 2/12/2019 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - February 12, 2019 Category: Cancer & Oncology Source Type: news

Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take It
(Source: Cancercompass News: Colorectal Cancer)
Source: Cancercompass News: Colorectal Cancer - February 12, 2019 Category: Cancer & Oncology Source Type: news

Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take It
(Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - February 12, 2019 Category: Cancer & Oncology Source Type: news

Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take It
MONDAY, Feb. 11, 2019 -- People with colon polyps spotted during screening are at higher risk for colon cancer. But while low-dose aspirin could lower the odds for the disease, too few patients adopt the regimen, new research shows. Advanced colon... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 11, 2019 Category: General Medicine Source Type: news

New evidence shows that walnuts optimize the gut microbiome to suppress colon cancer cell growth
(Natural News) Walnuts (Juglans regia) are popular among vegans because these nuts are rich in omega-3 fatty acids. Additionally, walnuts are full of nutrients that can help boost brain and cardiovascular health. But according to a study, walnuts can also help optimize the gut microbiome “to suppress colon cancer cell growth.” To date, colon cancer is the... (Source: NaturalNews.com)
Source: NaturalNews.com - February 10, 2019 Category: Consumer Health News Source Type: news

Molecular Profiling Is Key to GI Cancer Treatment Success Molecular Profiling Is Key to GI Cancer Treatment Success
John Marshall reports on treatment trials in gastric, pancreatic, and colon cancers, from the 2019 GI Cancers Symposium.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 7, 2019 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

Aspirin to prevent colon cancer underutilized in high-risk patients
(Florida Atlantic University) The US Preventive Services Task Force (USPSTF) concluded that aspirin reduces the risk of colorectal cancer by 40 percent as well as recurrence of advanced polyps, which are a major risk factor. To explore whether high risk patients are adhering to USPSTF guidelines, FAU researchers analyzed data from structured interviews with 84 patients and found that less than half (42.9 percent) reported taking aspirin. These findings pose major challenges that require multifactorial approaches by physicians and patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 7, 2019 Category: Cancer & Oncology Source Type: news

Too Much TV Raises Women's Odds for Early-Onset Colon Cancer: Study
Title: Too Much TV Raises Women's Odds for Early-Onset Colon Cancer: StudyCategory: Health NewsCreated: 2/5/2019 12:00:00 AMLast Editorial Review: 2/6/2019 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - February 6, 2019 Category: Cancer & Oncology Source Type: news

Too Much TV Raises Women's Odds for Early-Onset Colon Cancer: Study
TUESDAY, Feb. 5, 2019 -- Binge-watching series after series might be fun, but too much TV could raise a middle-aged woman's odds for colon cancer, a new study finds. Reporting Feb. 5 in JNCI Cancer Spectrum, researchers tracked data for more than... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 5, 2019 Category: General Medicine Source Type: news

Cannabinoid compounds may inhibit growth of colon cancer cells
Medical marijuana has gained attention in recent years for its potential to relieve pain and short-term anxiety and depression. Now, Penn State College of Medicine researchers say some cannabinoid compounds may actually inhibit the growth of colon cancer cells in the lab. (Source: World Pharma News)
Source: World Pharma News - February 5, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Cannabinoid compounds may inhibit growth of colon cancer cells
(Penn State) Medical marijuana has gained attention in recent years for its potential to relieve pain and short-term anxiety and depression. Now, Penn State College of Medicine researchers say some cannabinoid compounds may actually inhibit the growth of colon cancer cells in the lab. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 5, 2019 Category: Cancer & Oncology Source Type: news

Too Much TV Raises Women's Odds for Early-Onset Colon Cancer: Study
(Source: Cancercompass News: Colorectal Cancer)
Source: Cancercompass News: Colorectal Cancer - February 5, 2019 Category: Cancer & Oncology Source Type: news

Too Much TV Raises Women's Odds for Early-Onset Colon Cancer: Study
(Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - February 5, 2019 Category: Cancer & Oncology Source Type: news

Check-Cap raises $8m
Check-Cap (NSDQ:CHEK) said today that it inked a direct registered offering deal worth approximately $7.5 million to support the continued development of its C-Scan system. The Israel-based company’s C-Scan system is designed as an alternative to standard colon cancer screening methods. The system uses an ingestible, ultra-low dose X-ray capsule and a wireless tracking system to return structural information on the lumen of the colon to create 2D and 3D maps. In the placement, Check-Cap said that it sold approximately 2.9 million units, consisting of a single ordinary share and a warrant to purchase one half of ...
Source: Mass Device - February 4, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Wall Street Beat Check-Cap Source Type: news

Obesity-Linked Cancers On the Rise in Young Adults
In the study, the cancer incidence increases were particularly severe in six of the 12 obesity-related cancers: colon, uterine, gallbladder, kidney and pancreas, and multiple myeloma -- a bone marrow cancer. (Source: WebMD Health)
Source: WebMD Health - February 4, 2019 Category: Consumer Health News Source Type: news

Exercise Your Right to Fight Disease
MONDAY, Feb. 4, 2019 -- Research consistently tells you just how important exercise is for health. It can help head off heart disease, stroke, diabetes and many types of cancer, including breast and colon cancers. A report published in the New... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 4, 2019 Category: General Medicine Source Type: news

Obesity Tied to Higher Cancer Rates in Younger People
For six of the 12 obesity-related cancers (multiple myeloma, colorectal, uterine, gallbladder, kidney and pancreatic) the risk for disease increased in adults 25 to 49. (Source: NYT Health)
Source: NYT Health - February 4, 2019 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Obesity Weight Cancer Pancreas Multiple Myeloma Colon and Colorectal Cancer Source Type: news

When mucus can be key to treating colon and airway diseases
(Center for Genomic Regulation) New research reveals how healthy cells in our bodies produce mucins -- the main component of mucous, which protects our intestine and airway from pathogens, toxins and allergens. Scientists have already linked defects in mucins secretion to airway and colonic diseases, such as asthma or ulcerative colitis. Now, researchers at Malhotra's laboratory in Barcelona, reveal how cells control quantities of mucin released and could become a new avenue to treat several mucin-related diseases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 1, 2019 Category: Cancer & Oncology Source Type: news

Colon Cancer Screening Controversy. Here's What All The Debate Is About.
Recently, the American Cancer Society (ACS) recommended that colon cancer screenings start at age 45, based in large part on an uptick in the number of people 45-50 years old being diagnosed with colon cancer. But the ACS might be recommending more cancer screening than the American public needs. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 31, 2019 Category: Pharmaceuticals Authors: Peter Ubel, Contributor Source Type: news

Advances in Molecular Subtyping of Colon Cancer
Cancer Network spoke with Dr. Scott Kopetz about RNA-based subtyping and the challenge of spreading the word of the importance of biomarker testing in colorectal cancer. (Source: CancerNetwork)
Source: CancerNetwork - January 31, 2019 Category: Cancer & Oncology Authors: Scott Kopetz, MD Source Type: news

SLUCare partners with Israeli tech company for AI project
SLUCare has announced a partnership with an Israel tech company that uses artificial intelligence to predict future gastrointestinal (GI) disorders. Medial EarlySign has created LGI Flag, a machine-learning tool that sources electronic health record data to identify patients who may be at high risk for lower GI tract disorders such as colon cancer, irritable bowel disease (IBS), ulcers, chronic bleeding and other ailments.   Dr. William Mana rd, chief medical informatics officer at SLUCare Family… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - January 24, 2019 Category: Biotechnology Authors: Brian Robbins Source Type: news

' Poop Transplants' May Help Ease Painful Colitis
TUESDAY, Jan. 22, 2019 -- Ulcerative colitis is a chronic inflammatory bowel disease triggering pain and bloody stools, and it can raise the odds for colon cancer. But now, research suggests that fecal transplants -- basically, delivering a healthy... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 22, 2019 Category: General Medicine Source Type: news

White blood cells related to allergies may also be harnessed to destroy cancer cells
(American Friends of Tel Aviv University) A new Tel Aviv University study finds that white blood cells which are responsible for chronic asthma and modern allergies may be used to eliminate malignant colon cancer cells. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 22, 2019 Category: Cancer & Oncology Source Type: news

Congress Funds Feasibility Study for Mesothelioma Patient Registry
The National Institute for Occupational Safety and Health will oversee a study in 2019 to determine the feasibility of establishing the first national mesothelioma patient registry. The $100,000 feasibility study was part of the $1.2 million Congress allocated in 2019 to the Centers of Disease Control and Prevention for mesothelioma research. The bulk of the funding goes toward the National Mesothelioma Virtual Bank, which is a biospecimen registry first established in 2006. It is the only federally funded program designed exclusively for the research of mesothelioma, the rare and aggressive cancer caused by asbestos expos...
Source: Asbestos and Mesothelioma News - January 15, 2019 Category: Environmental Health Authors: Matt Mauney Source Type: news

Scientists connect dots between colitis and colon cancer
(Medical College of Georgia at Augusta University) Lingering inflammation in the colon is a known risk factor for colorectal cancer and now scientists report one way it resets the stage to enable this common and often deadly cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 14, 2019 Category: International Medicine & Public Health Source Type: news

Want to Prevent the Deadliest Diseases? Eat More Fiber
If you want to eat something for better health, make it fiber. That’s the advice from nutrition experts and the latest national dietary guidelines. Now, a large new review of studies on fiber, published in the Lancet, shows just how beneficial fiber can be. The nutrient substantially lowers the risk of at least four diseases—many of which don’t even directly relate to the gut. Compared to those who ate less fiber, people who ate more fiber lowered their risk of heart disease, stroke, type 2 diabetes and colon cancer, as well as their risk of dying early from any cause, by 15% to 30%. And the more dietary ...
Source: TIME: Health - January 10, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Cancer Diet/Nutrition healthytime Heart Disease Source Type: news

Global colorectal cancer mortality rates predicted to rise
(Wiley) In the first effort to predict the future burden of colorectal cancer mortality globally, researchers note that colon and rectal cancer mortality rates are projected to decrease in most countries apart from some Latin American and Caribbean countries, but increases are predicted for several countries from Europe, North America and Oceania. The findings are published in the International Journal of Cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 9, 2019 Category: International Medicine & Public Health Source Type: news

U.S. Cancer Death Rate Plummets From 1991 Peak
(CBS Local) — The nation’s cancer death rate dropped a whopping 27 percent during the last quarter century, according to a new report by the American Cancer Society. That translates to about 2.6 million fewer cancer deaths than would have been expected if rates stayed at their peak, which was seen in 1991. “The decline in deaths is largely driven by reductions in smoking and improved treatment, as well as earlier detection for some cancers,” said lead researcher Rebecca Siegel, scientific director of surveillance research at the cancer society. The drop was driven by huge strides made in treating mo...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 8, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News American Cancer Society Local TV talkers Source Type: news

Noninvasive Test for Colon Cancer Screening Offered as an Alternative to Colonoscopy for Screening
“The only real cure for cancer is finding it early,” said Padma Sundar, vice president of strategy and market access at CellMax Life, in an interview with MD+DI. In terms of colorectal cancer, she said it takes a long time for an adenoma to develop into cancer, so early detection of these adenomas can be lifesaving. But colonoscopy, although the gold standard of adenoma and colon cancer detection, has issues with patient compliance. There are about 125 million Americans, 45 years old and older, who are advised to have routine screening for colorectal cancer. “Unfortunat...
Source: MDDI - January 8, 2019 Category: Medical Devices Authors: Susan Shepard Tags: IVD Source Type: news

Exact Sciences' stock rises as company anticipates $455M in 2018 revenue
Exact Sciences Corp., the Madison manufacturer of the Cologuard take-home colon cancer test, saw its stock rise sharply in early-morning trading Monday after the company posted estimations for its recent fourth quarter and full-year 2018 revenue. The company's fourth-quarter sales would range between $142.5 million and $143.5 million, the company said in a news release, which would be an increase of 64 percent when compared with the same quarter of 2017. For its full year 2018 results, Exact Sciences… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - January 7, 2019 Category: Pharmaceuticals Authors: Nick Williams Source Type: news

Will new USPSTF review lead to CT colonography payment?
The U.S. Preventive Services Task Force (USPSTF) has opened a review of its...Read more on AuntMinnie.comRelated Reading: Groups urge mandated coverage for CT colonography Insurance coverage for CTC boosts screening CMS declines to revisit CT colonography coverage USPSTF greenlights CT colonography for screening Colon cancer group criticizes USPSTF guidelines (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 4, 2019 Category: Radiology Source Type: news

Can CTC improve staging for high-risk colon cancer?
CT colonography (CTC) may be better than conventional CT for staging high-risk...Read more on AuntMinnie.comRelated Reading: Calcium scores on CT colonography predict cardiac events Study confirms low rate of incidental findings on CTC CT colonography finds more cancer in seniors Does colonoscopy top CTC for cancer screening? Insurance coverage for CTC boosts screening (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 4, 2019 Category: Radiology Source Type: news

Heart Attack May Be Early Sign of Cancer
The risk of a heart attack or stroke rose in patients who would later be diagnosed with cancer. (Source: NYT Health)
Source: NYT Health - December 21, 2018 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Heart Stroke Cancer Colon and Colorectal Cancer Lung Cancer Source Type: news

Health Tip: How Alcohol May Raise Cancer Risk
-- Alcohol use has been associated with cancers of the mouth, throat, voice box, esophagus, liver, colon, rectum and breast, the American Cancer Society says. The society describes how alcohol can affect the body, noting that the more you drink,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 19, 2018 Category: General Medicine Source Type: news

IASLC successfully pilots early lung imaging confederation project
(International Association for the Study of Lung Cancer) Evidence proves that screening saves lives, with screening for breast, colon, prostate and cervical cancers, for example, being accepted in many parts of the world as a routine part of medical care. While generally caught in the later stages, lung cancer survival curves show that the has much better outcomes when it is caught early, so developing a lung cancer screening protocol could lead to dramatic improvements in patient care and ultimately reductions in mortality. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 19, 2018 Category: Cancer & Oncology Source Type: news

10-year colonoscopy follow-ups decrease death risk in patients, study says
A 10-year follow-up after an initial negative colonoscopy greatly reduces a person's risk of dying from colon cancer, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 17, 2018 Category: Consumer Health News Source Type: news

10-year colonoscopy follow-ups decrease colon cancer death risk, study says
A 10-year follow-up after an initial negative colonoscopy greatly reduces a person's risk of dying from colon cancer, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 17, 2018 Category: Consumer Health News Source Type: news

Ask Well: Is Eating Deli Meats Really That Bad for You?
Even small amounts of processed meat increase the risk of colorectal cancer. (Source: NYT Health)
Source: NYT Health - December 14, 2018 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Meat Colon and Colorectal Cancer Diet and Nutrition Labeling and Labels (Product) Oils and Fats Source Type: news

Living With Cancer: When can you stop colon cancer screening?
Colon cancer screening: At what age can you stop? People older than 75 who have been getting regular colon cancer screening since age 50 and who have had consistently negative screenings ? no polyps or colon cancer, and who are not at an increased risk of colon cancer because of family history, may not need [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 14, 2018 Category: Databases & Libraries Source Type: news

Colorectal Cancer Screening Pill to Be in US Pilot Study
Check-Cap is getting one step closer to having its capsule-based screening method for colorectal cancer on the U.S. market. The Isfiya, Israel-based company has received FDA conditional approval for an IDE to initiate a pilot study of the C-Scan capsule. FDA’s conditional approval of the IDE requires Check-Cap to provide additional information to the agency and the company may begin enrolling patients immediately upon approval by the study site's Institutional Review Board (IRB). The trial will consist of up to 45 patients and it will be a single-arm study. Patients who are enrolled will be those conside...
Source: MDDI - December 13, 2018 Category: Medical Devices Authors: Omar Ford Tags: Regulatory and Compliance Implants Source Type: news

Check-Cap wins conditional IDE approval for C-Scan pilot study
Check-Cap (NSDQ:CHEK) said today it won conditional approval from the FDA for its investigational device exemption application to launch a pilot study of its C-Scan system. The Israel-based company’s C-Scan system is designed as an alternative to standard colon cancer screening methods. The system uses an ingestible, ultra-low dose X-ray capsule and a wireless tracking system to return structural information on the lumen of the colon to create 2D and 3D maps. The conditional approval will require Check-Cap to provide additional information to the FDA, but will allow the company to being enrolling patients immedi...
Source: Mass Device - December 13, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Diagnostics Food & Drug Administration (FDA) Check-Cap Source Type: news

Cancer Incidence Rising Rapidly Around the World
More than 30,000 people around the world will be diagnosed with malignant mesothelioma cancer in 2018, according to the latest estimates by the International Agency for Research on Cancer. Almost 26,000 will die from the disease. The numbers on mesothelioma were part of a larger report that included 36 types of cancer. The research covered 185 countries throughout 20 regions. It was published in the November/December issue of CA: A Cancer Journal for Clinicians. An estimated 18.1 million new cancer cases and 9.6 million cancer deaths are expected in 2018, a significant rise from 2012, when the agency published its last stu...
Source: Asbestos and Mesothelioma News - December 13, 2018 Category: Environmental Health Authors: Daniel King Source Type: news

Ask Well: Do Cruciferous Vegetables Really Fight Cancer?
You cannot go wrong incorporating a lot of cruciferous vegetables, which include broccoli and brussels sprouts as well as dark leafy greens like kale and arugula, in your diet. (Source: NYT Health)
Source: NYT Health - December 7, 2018 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Vegetables Head and Neck Cancer Colon and Colorectal Cancer Lung Cancer Breast Cancer Diet and Nutrition Vitamins Dietary Supplements and Herbal Remedies Throat Prostate Gland Source Type: news

Early Screening Key to Reducing Lung Cancer Deaths
Radiation oncologist Dr. Andrea McKee believes deaths from lung cancer — including those related to asbestos exposure — could be reduced significantly by increased utilization of early CT screening. McKee, chair of radiation oncology at Lahey Hospital and Medical Center in Burlington, Maine, has been a strong proponent of early screening for several years. “We could be saving tens of thousands of lives every year with this,” McKee told The Mesothelioma Center at Asbestos.com. “There is nothing else like it. The life-saving potential is the most important thing that has happened to cancer in my...
Source: Asbestos and Mesothelioma News - December 4, 2018 Category: Environmental Health Authors: Matt Mauney Source Type: news

Study discovers 40 new genetic variants associated with colorectal cancer risk
(Fred Hutchinson Cancer Research Center) The most comprehensive genome-wide association study, or GWAS, of colorectal cancer risk to date, published today in Nature Genetics, has discovered 40 new genetic variants and validated 55 previously identified variants that signal an increased risk of colon cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 3, 2018 Category: Cancer & Oncology Source Type: news