Colorectal cancer and women
YSPH professor Caroline Johnson ’s pathbreaking research on metabolites helps explains why women are more at risk for a deadlier type of colorectal cancer. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 22, 2021 Category: Universities & Medical Training Source Type: news

Building a Better FIT Test for Colon Cancer Screening Building a Better FIT Test for Colon Cancer Screening
An antibody-based multitarget FIT for colorectal cancer screening is more accurate in detecting advanced neoplasia compared with the standard FIT test, report Dutch researchers.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 20, 2021 Category: Gastroenterology Tags: Hematology-Oncology News Source Type: news

Benefits From Moving More, Sitting Less for CRC Survivors Benefits From Moving More, Sitting Less for CRC Survivors
More physical activity and less sedentary behavior are associated with better quality of life and less fatigue among colorectal cancer (CRC) survivors up to 2 years after treatment.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 19, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Oncotarget: RAS reversion in colorectal cancer patients treated with bevacizumab
(Impact Journals LLC) This Oncotarget finding might have potential therapeutic implications, as anti-EGFR could be reconsidered in primarily RAS mutant patients reverted to a wild-type status after bevacizumab exposure. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 16, 2021 Category: Cancer & Oncology Source Type: news

Racial Disparities in Recurrence and Overall Survival in CRC Racial Disparities in Recurrence and Overall Survival in CRC
A better understanding of the racial disparities that exist in the recurrence and mortality of colorectal cancer could help improve outcomes among these patients.Journal of the National Cancer Institute (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 14, 2021 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

VOC Analysis to Improve FIT in the Detection of CRC VOC Analysis to Improve FIT in the Detection of CRC
Might the addition of a volatile organic compound test improve the accuracy of fecal immunochemical testing for the detection of colorectal cancer?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 14, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

New WHO study links moderate alcohol use with higher cancer risk
(Centre for Addiction and Mental Health) A new study from the World Health Organization's (WHO) International Agency for Research on Cancer (IARC), published in the journal Lancet Oncology, has found an association between alcohol and a substantially higher risk of several forms of cancer, including breast, colon, and oral cancers. Increased risk was evident even among light to moderate drinkers (up to two drinks a day), who represented 1 in 7 of all new cancers in 2020 and more than 100,000 cases worldwide. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 14, 2021 Category: International Medicine & Public Health Source Type: news

Alcohol caused 740,000 cancer cases globally last year – study
Researchers behind estimate say more needs to be done to raise public awareness of linkAlcohol is estimated to have caused more than 740,000 cancer cases around the world last year, and experts say more needs to be done to highlight the link.There is strong evidence that alcohol consumption can cause various cancers including those of the breast, liver, colon, rectum, oropharynx, larynx and oesophagus. Research suggests that evenlow levels of drinking can increase the risk.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 13, 2021 Category: Science Authors: Nicola Davis Science correspondent Tags: Alcohol Cancer Medical research Breast cancer Health Science Society Source Type: news

St. Louis startup Geneoscopy reaches key milestone for its cancer screening test
The startup has enrolled the first patient in a clinical trial for its at-home colon cancer screening test. It's technology the company says is designed to more easily detect the cancer than current methods. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 13, 2021 Category: Pharmaceuticals Authors: Nathan Rubbelke Source Type: news

WCG buys imaging core lab Intrinsic Imaging
Clinical trials services and technology provider WCG has purchased medical imagin...Read more on AuntMinnie.comRelated Reading: Intrinsic taps new VP Intrinsic Imaging joins colorectal cancer trial (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 13, 2021 Category: Radiology Source Type: news

Cardiff Oncology Announces the Appointments of Katherine L. Ruffner, M.D., as Chief Medical Officer and James E. Levine as Chief Financial Officer
Dr. Ruffner is a US-trained hematologist/oncologist with over 25 years of clinical care, oncology biotechnology and pharmaceutical drug development experience Mr. Levine has over 20 years of corporate and investment banking experience in the biotechnolo... Biopharmaceuticals, Oncology, Personnel Cardiff Oncology, Onvansertib, Colorectal Cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 12, 2021 Category: Pharmaceuticals Source Type: news

Hijacked immune activator promotes growth and spread of colorectal cancer
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) Through a complex, self-reinforcing feedback mechanism, colorectal cancer cells make room for their own expansion by driving surrounding healthy intestinal cells to death - while simultaneously fueling their own growth. This feedback loop is driven by an activator of the innate immune system. Researchers from the German Cancer Research Center (DKFZ) and the University of Heidelberg discovered this mechanism in the intestinal tissue of fruit flies. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 12, 2021 Category: Biology Source Type: news

STELARA ® (ustekinumab) Demonstrated Sustained Symptomatic and Corticosteroid-Free Remission Rates in Adults with Moderately to Severely Active Ulcerative Colitis at Nearly Three Years in Long-Term Extension of Phase 3 Trial
SPRING HOUSE, PENNSYLVANIA, July 9, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new three-year data from the long-term extension (LTE) of the STELARA® (ustekinumab) Phase 3 UNIFI study. The data demonstrated the majority (55.2 percent) of adult patients with moderately to severely active ulcerative colitis (UC) who initially responded to treatment with STELARA sustained symptomatic remissiona rates at nearly three years (week 152).1 Furthermore, a majority (96.4 percent) of the patients in symptomatic remissiona at week 152 were corticosteroid-free. These data are being pr...
Source: Johnson and Johnson - July 9, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

NIH researchers expand Families SHARE, an educational genomics workbook
(NIH/National Human Genome Research Institute) Researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 8, 2021 Category: Biology Source Type: news

Cancer screenings rebounded in 2020 after COVID but racial disparities remain
(Dana-Farber Cancer Institute) Testing returned to pre-pandemic levels in late 2020 except with colonoscopies for colorectal cancer screening, which continued to lag. Rates of mammography for breast cancer screening were lower among Black and Hispanic patients during the pandemic. Long term effects of " missed " diagnoses on cancer outcomes not yet clear. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

The shape of nanoparticles in body fluids may help identify the type of cancer
(Nagoya University) A recent study has shown that the shape of cell-derived nanoparticles, known as " extracellular vesicles " (EVs), in body fluids could be a biomarker for identifying types of cancer. In the study, scientists successfully measured the shape distributions of EVs derived from liver, breast, and colorectal cancer cells, showing that the shape distributions differ from one another. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

Cancer screenings rebounded in late 2020 after COVID-related decline, but racial and economic disparities remain for some tests
Testing returned to pre-pandemic levels in late 2020 except with colonoscopies for colorectal cancer screening, which continued to lag; rates of mammography for breast cancer screening were lower among Black and Hispanic patients during the pandemic (Source: BWH News)
Source: BWH News - July 7, 2021 Category: Hospital Management Source Type: news

Could Too Many Antibiotics Raise Your Odds for Colon Cancer?
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - July 6, 2021 Category: Cancer & Oncology Tags: Infections, Oncology, News, Source Type: news

Could Too Many Antibiotics Raise Your Odds for Colon Cancer?
TUESDAY, July 6, 2021 -- Antibiotics may increase the risk of colon cancer, especially in younger people, U.K. researchers report. " To our knowledge, this is the first study to link antibiotic use with the growing risk of early-onset colon cancer --... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 6, 2021 Category: General Medicine Source Type: news

Too Little Sunlight, Vitamin D May Raise Colon Cancer Risk
Title: Too Little Sunlight, Vitamin D May Raise Colon Cancer RiskCategory: Health NewsCreated: 7/5/2021 12:00:00 AMLast Editorial Review: 7/6/2021 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - July 6, 2021 Category: Cancer & Oncology Source Type: news

Could Too Many Antibiotics Raise Your Odds for Colon Cancer?
Title: Could Too Many Antibiotics Raise Your Odds for Colon Cancer?Category: Health NewsCreated: 7/6/2021 12:00:00 AMLast Editorial Review: 7/6/2021 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - July 6, 2021 Category: Cancer & Oncology Source Type: news

Colorectal cancer risk may increase with lower exposure to UVB light
(University of California - San Diego) University of California San Diego School of Medicine researchers identified a possible link between inadequate exposure to ultraviolet-B (UVB) light from the sun and an increased risk of colorectal cancer. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 6, 2021 Category: Biology Source Type: news

Poorer Survival in CRC With Obesity: Is Chemo Dose Too Low? Poorer Survival in CRC With Obesity: Is Chemo Dose Too Low?
Could poorer survival outcomes seen in patients with colorectal cancer and obesity be partially explained by lower cumulative doses of adjuvant chemotherapy?Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 5, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Antibiotic Link to Rise in Early Onset Colon Cancer? Antibiotic Link to Rise in Early Onset Colon Cancer?
Any antibiotic exposure appears to increase the risk of colon cancer by almost 50% in people aged under 50 years, say UK researchers, although experts warn more work is needed to show causality.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 5, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Antibiotic Linked to Rise in Early-Onset Colon Cancer? Antibiotic Linked to Rise in Early-Onset Colon Cancer?
Any antibiotic exposure appears to increase the risk of colon cancer by almost 50% in people aged under 50 years, say UK researchers, although experts warn more work is needed to show causality.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 5, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Too Little Sunlight, Vitamin D May Raise Colon Cancer Risk
MONDAY, July 5, 2021 -- New research finds that countries with more cloudy days tend to have higher colon cancer rates. Lower levels of vitamin D, the " sunshine vitamin, " may be to blame. So, boosting your vitamin D levels through exposure to... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 5, 2021 Category: General Medicine Source Type: news

Colon Cancer Rising in Young Adults, Linked to Sugary Drinks
As consumption of sugar-laden drinks rose in the 1980s and ’90s, so did colorectal cancer rates among younger adults, a study in nurses found. (Source: NYT Health)
Source: NYT Health - July 5, 2021 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Colon and Colorectal Cancer Sugar Weight Obesity Gut (Journal) Diet and Nutrition Source Type: news

Lower exposure to UVB light may increase colorectal cancer risk
(BMC (BioMed Central)) Inadequate exposure to UVB light from the sun may be associated with an increased risk of colorectal cancer, particularly in older age groups, according to a study using data on 186 countries, published in the open access journal BMC Public Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 4, 2021 Category: International Medicine & Public Health Source Type: news

Bowel cancer data reinforce need to reduce unnecessary antibiotic use
(European Society for Medical Oncology) Doctors and patients are being advised to reduce unnecessary antibiotic use following new data suggesting that these medicines may increase the risk of cancer of the large intestine (colon), especially in people under 50 years. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 2, 2021 Category: Cancer & Oncology Source Type: news

Poorer survival in obese colorectal cancer patients possibly linked to lower chemotherapy doses
(European Society for Medical Oncology) Obese patients with colorectal cancer receive lower cumulative doses of adjuvant chemotherapy, relative to their body surface area (BSA), than non-obese patients, show results from a large meta-analysis reported at the ESMO World Congress on Gastrointestinal Cancer 2021. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 2, 2021 Category: Cancer & Oncology Source Type: news

Tumor cell PD-L1 may mediate sensitivity to chemotherapy in colorectal cancer treatment
ROCHESTER, Minn. — Data in a study by Mayo Clinic Cancer Center researchers indicates that the level of tumor cell PD-L1, a protein that acts as a brake to keep the body's immune responses under control, may be an important factor for sensitivity to chemotherapy in colorectal cancer treatment. The study was published Friday, July 2, in Oncogene. "We have identified a mechanism by which absent or low levels of tumor cell PD-L1, which is commonly found… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - July 2, 2021 Category: Research Source Type: news

New Data Support De-escalating Chemotherapy in Colorectal Cancer New Data Support De-escalating Chemotherapy in Colorectal Cancer
KEYNOTE-177 reaffirms pembro in mismatch repair-deficient colorectal cancer, and two other studies support easing off chemo to improve PFS in advanced disease.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 30, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

Home Test for Colon Cancer Can Lead to Unexpected Medical Bill
Follow - up colonoscopy often classified as'diagnostic'test, not'routine screening,'and therefore not covered by insurance (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 29, 2021 Category: Cancer & Oncology Tags: Gastroenterology, Internal Medicine, Oncology, Institutional, Source Type: news

Home Test for Colon Cancer Can Lead to Unexpected Medical Bill
TUESDAY, June 29, 2021 -- Consumers are finding that if they choose to complete a popular colon cancer screening test that can be performed at home, and it comes back positive, the follow-up colonoscopy may not be covered by insurance. Recently, a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 29, 2021 Category: Pharmaceuticals Source Type: news

Could Home Test for Colon Cancer Mean a Big Medical Bill to Come?
Title: Could Home Test for Colon Cancer Mean a Big Medical Bill to Come?Category: Health NewsCreated: 6/28/2021 12:00:00 AMLast Editorial Review: 6/29/2021 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - June 29, 2021 Category: Cancer & Oncology Source Type: news

More efficient tests may one day replace endoscopy
(University of Houston) A University of Houston biomedical researcher is widening the net, looking for symptoms of other proteins -- not just blood - found elevated in colorectal cancer and inflammatory bowel disease. The new biomarkers may one day replace the invasive endoscopy to determine what's going on inside the intestines. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 29, 2021 Category: Biology Source Type: news

Could Home Test for Colon Cancer Mean a Big Medical Bill to Come?
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 28, 2021 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Oncology, Preventive Medicine, News, Source Type: news

Early-Onset CRC Associated With Longer Survival Early-Onset CRC Associated With Longer Survival
Individuals who are younger than 50 years when diagnosed with primary colorectal cancer have better survival outcomes than individuals diagnosed at age 51-55 years.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 28, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Could Home Test for Colon Cancer Mean a Big Medical Bill to Come?
MONDAY, June 28, 2021 -- You decide to take a popular colon cancer screening test that can be performed at home, and it comes back positive. A follow-up colonoscopy is scheduled, but then you suddenly receive a large and unexpected medical... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 28, 2021 Category: General Medicine Source Type: news

Oncotarget: Novel markers of colorectal tumors exhibiting microsatellite instability
(Impact Journals LLC) By incorporating cell composition into their regression model, they identified 3,193 differentially expressed genes, of which 556 were deemed novel. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 28, 2021 Category: Cancer & Oncology Source Type: news

Survival Up for Colon Cancer Patients in U.S. Military Health System
Survival better compared with colon cancer patients in the general U.S. population, overall and in subgroups including Black versus White race (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 25, 2021 Category: Cancer & Oncology Tags: Gastroenterology, Oncology, Pathology, Pharmacy, Radiology, Journal, Source Type: news

Survival Up for Colon Cancer Patients in U.S. Military Health System
FRIDAY, June 25, 2021 -- Patients with colon cancer who are in the U.S. military health system, with universal health care, have better survival than those in the general U.S. population, according to a study published online June 23 in Cancer... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 25, 2021 Category: Pharmaceuticals Source Type: news

Detecting Colorectal Cancer Before Age 40 Yields Small Survival Benefit Detecting Colorectal Cancer Before Age 40 Yields Small Survival Benefit
New research suggests a small survival benefit for people with early-onset colorectal cancer, particularly those aged 35 to 39 years, compared with diagnosis at later ages.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - June 25, 2021 Category: Gastroenterology Tags: Hematology-Oncology News Source Type: news

CRC Mortality Risk Correlates With Adenoma Detection Rate CRC Mortality Risk Correlates With Adenoma Detection Rate
High-quality colonoscopy was associated with a lower risk of death from colorectal cancer, especially among those with high-risk adenomas, according to a recent study.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - June 24, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Universal health care benefited colon cancer survival
(American Association for Cancer Research) Patients with colon cancer enrolled in the U.S. military's universal health care system experienced improved survival compared with patients in the general population, according to results published in Cancer Epidemiology, Biomarkers& Prevention. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 23, 2021 Category: Cancer & Oncology Source Type: news

Simple Blood Test to Detect Colorectal Cancer Simple Blood Test to Detect Colorectal Cancer
In patients already diagnosed with early stage colorectal cancer, the test achieved overall sensitivity of 91% and specificity of 94%. Validation studies are ongoing.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 22, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Older Age, Black or Hispanic Race Tied to Higher Risk for Colorectal Cancer
TUESDAY, June 22, 2021 -- Age and race/ethnicity are independently associated with the overall risk for colorectal cancer (CRC) among veterans, according to a study published online May 28 in the Journal of Clinical Gastroenterology. Thomas F.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 22, 2021 Category: Pharmaceuticals Source Type: news

When to Stop Cancer Screening: Clinicians' Calculus Varies When to Stop Cancer Screening: Clinicians' Calculus Varies
Primary care physicians are more likely to use a strict age cutoff for stopping colon cancer screening than they are for stopping breast and prostate cancer screening, new data suggest.Medscape Medical News (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - June 22, 2021 Category: Primary Care Tags: Family Medicine/Primary Care News Source Type: news

Ethicon Expands Advanced Biopolar Energy Portfolio With Launch Of Enseal X1 Curved Jaw Tissue Sealer
CINCINNATI, OH – June 21, 2021 -- Ethicon*, part of the Johnson & Johnson Medical Devices Companies,** today announced the launch of the ENSEAL X1 Curved Jaw Tissue Sealer, a new advanced bipolar energy device that increases procedural efficiency[1] and provided stronger sealing[2] and better access to more tissue than LigaSure™ Maryland.[3] The device is indicated for colorectal, gynecological, bariatric surgery and thoracic procedures. The ENSEAL X1 Curved Jaw is the first of several new advanced laparoscopic bipolar devices the company plans to launch in the coming months as it expands its extensive ener...
Source: Johnson and Johnson - June 21, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

ONCOS-102 Vaccine Showing Impressive Results for Mesothelioma
The novel immunotherapy vaccine ONCOS-102 may become the answer for the large percentage of mesothelioma cancer patients who fail to respond to a recently approved checkpoint inhibitor combination of treatment. ONCOS-102, a genetically modified oncolytic adenovirus, showed an overall survival rate of between 21.9 and 25 months in a randomized phase II clinical trial when combined with standard chemotherapy in a first-line setting. By comparison, patients in the trial receiving only standard chemotherapy had a median survival of just 13.5 months. The vaccine is the lead product of Targovax, a small Scandinavian bio...
Source: Asbestos and Mesothelioma News - June 17, 2021 Category: Environmental Health Authors: Fran Mannino Source Type: news