Landmark study finds one in two hospitalised COVID-19 patients develop a complication, NIHR
A large-scale, NIHR-supported observational study published in The Lancet has found that one in two people hospitalised with COVID-19 during the first phase of the pandemic developed at least one health complication as a result of the viral infection. The ISARIC/CO-CIN study is the most comprehensive of its kind - and the first to systematically assess a range of in-hospital complications and their associations with age, sex and ethnicity - and their outcomes for the patients. The researchers assessed more than 70,000 hospitalised adult patients in the UK hospitalised with severe COVID-19 disease between January and Augu...
Source: Current Awareness Service for Health (CASH) - July 26, 2021 Category: Consumer Health News Source Type: news

FDA grants Breakthrough Therapy Designation for Venclexta in combination with azacitidine for the treatment of patients with myelodysplastic syndromes
Basel, 21 July 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that Venclexta ® (venetoclax) in combination with azacitidine has been granted Breakthrough Therapy Designation (BTD) by the U.S. Food and Drug Administration (FDA) for the treatment of adult patients with previously untreated intermediate, high- and very high-risk myelodysplastic syndromes (MDS) based on the rev ised International Prognostic Scoring System (IPSS-R). MDS are a rare group of blood cancers that gradually affect the ability of the bone marrow to produce normal blood cells.2 This can lead to weakness, frequent infections, anaemia and ...
Source: Roche Media News - July 21, 2021 Category: Pharmaceuticals Source Type: news

FDA grants Breakthrough Therapy Designation for Venclexta in combination with azacitidine for the treatment of patients with myelodysplastic syndromes
Basel, 21 July 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that Venclexta ® (venetoclax) in combination with azacitidine has been granted Breakthrough Therapy Designation (BTD) by the U.S. Food and Drug Administration (FDA) for the treatment of adult patients with previously untreated intermediate, high- and very high-risk myelodysplastic syndromes (MDS) based on the rev ised International Prognostic Scoring System (IPSS-R). MDS are a rare group of blood cancers that gradually affect the ability of the bone marrow to produce normal blood cells.2 This can lead to weakness, frequent infections, anaemia and ...
Source: Roche Investor Update - July 21, 2021 Category: Pharmaceuticals Source Type: news

What Happens to a Person with Sickle Cell Anemia
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - July 20, 2021 Category: General Medicine Source Type: news

Vitamin B12 deficiency: Toiletry troubles indicative of long-term deficiency
A VITAMIN B12 deficiency can escalate to anaemia - a lack of healthy red blood cells, which means that less oxygen is delivered to vital organs. As time goes on, symptoms will begin to emerge. (Source: Daily Express - Health)
Source: Daily Express - Health - July 18, 2021 Category: Consumer Health News Source Type: news

Sandoz launches first generic high dose intravenous iron, Ferumoxytol Injection, to treat US patients with iron deficiency anemia
Patients with iron deficiency anemia in a hospital or clinic setting now have access to an important IV iron medicine at a more affordable price Iron deficiency anemia occurs when there is a lower than normal number of oxygen-carrying red blood cells be... Biopharmaceuticals, Generics, Product Launch Sandoz, Novartis, Ferumoxytol, iron deficiency (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 16, 2021 Category: Pharmaceuticals Source Type: news

FDA Panel Rejects Roxadustat for Anemia in Kidney Disease FDA Panel Rejects Roxadustat for Anemia in Kidney Disease
An FDA advisory committee voted by 1-13 and 2-12 margins against approving a novel, oral agent, roxadustat, for treating anemia in patients with chronic kidney disease. Safety was the major issue.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 16, 2021 Category: Consumer Health News Tags: Nephrology News Source Type: news

Status on FDA Advisory Committee Vote on Roxadustat in Anemia of Chronic Kidney Disease
16 July 2021 -- The Food and Drug Administration’s (FDA) Cardiovascular and Renal Drugs Advisory Committee (CRDAC) has voted 13 to 1 that the benefit-risk profile of roxadustat does not support approval for the treatment of anemia in chronic... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - July 16, 2021 Category: Drugs & Pharmacology Source Type: news

Iron Deficiency May Increase Mortality, CV Risks in Nondialysis CKD
WEDNESDAY, July 14, 2021 -- For patients with nondialysis chronic kidney disease (CKD), with or without anemia, iron deficiency as reflected by a serum biomarker of iron stores is associated with an increased risk for all-cause mortality and major... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 14, 2021 Category: Pharmaceuticals Source Type: news

Iron Therapy May Help More Patients With Kidney Disease Iron Therapy May Help More Patients With Kidney Disease
Treating iron deficiency in patients with chronic kidney disease but without anemia may reduce their risk of death, particularly from cardiovascular causes, new research hints.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 12, 2021 Category: Consumer Health News Tags: Nephrology News Source Type: news

Vitamin B12 deficiency: Is your heart rate different? Warning symptom due to anaemia
VITAMIN B12 deficiency is extremely common with millions of people around the world lacking in the essential vitamin. Your heart rate could be a major sign indicating how deficient you may be. (Source: Daily Express - Health)
Source: Daily Express - Health - July 5, 2021 Category: Consumer Health News Source Type: news

What Problems are Ciliopathies Associated With?
Discussion Nephronophthisis (NPHP) one cause of end-stage renal disease (ESRD) usually occurring before age 30 years. NPHP is a non-motile ciliopathy affecting cellular sensing in the renal tubular epithelium. See To Learn More below. The incidence varies according to location with 1:1 million in the US but 1:50,000 in Finland. There are 3 subtypes: Infantile Occurs usually within 1 year of life Enlarged kidneys and severe hypertension In utero can have oligohydramnios problems such as pulmonary hypoplasia, facial dysmorphisms, limb contractures Extra-renal problems include congenital heart disease, liver fibrosis, recur...
Source: PediatricEducation.org - July 5, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Vitamin B12 deficiency: Expert warns of three ‘red flags’ to look out for
PHARMACIST Giulia Guerrini warned that a lack of vitamin B12 "can affect the nervous system and lead to macrocytic anaemia" - where enlarged red blood cells have low haemoglobin levels. (Source: Daily Express - Health)
Source: Daily Express - Health - July 4, 2021 Category: Consumer Health News Source Type: news

Vitamin B12 deficiency symptoms: Four neurological problems that might be 'irreversible'
VITAMIN B12 is necessary for the healthy functioning of the nervous system; an inadequate supply will cause megaloblastic anaemia, which is when enlarged red blood cells can not work properly. (Source: Daily Express - Health)
Source: Daily Express - Health - July 3, 2021 Category: Consumer Health News Source Type: news

EU Green Light for Roxadustat in Anemia of Kidney Disease EU Green Light for Roxadustat in Anemia of Kidney Disease
European Medicines Agency committee issues a positive opinion for roxadustat, which would be the first orally administered treatment for adults with CKD-associated anemia.International Approvals (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - June 29, 2021 Category: Transplant Surgery Tags: Nephrology News Alert Source Type: news

Nigeria: Sickle Cell Day - Author Calls for Awareness, Adequate Information
[Vanguard] Malam Shehu Mohammed, author of the book on sickle cell anaemia titled "I am a survivor," has called on Nigerians to create more awareness and sensitisation exercise to the sickle cell disease. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 20, 2021 Category: African Health Source Type: news

New Phase 3 Study Results Show IMBRUVICA ® (ibrutinib)-Based Combination Regimen as an All-Oral Fixed-Duration Treatment Demonstrated Superior Progression-Free Survival in Adult Patients with Previously Untreated Chronic Lymphocytic Leukemia
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced primary results from the pivotal Phase 3 GLOW study (NCT03462719) evaluating fixed-duration IMBRUVICA® plus venetoclax (I+V) compared to chlorambucil plus obinutuzumab (Clb+O) for first-line treatment of elderly or unfit patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study demonstrated superior progression-free survival (PFS) of a once-daily, all-oral, fixed-duration regimen of I+V versus Clb+O as first-line treatment of CLL; the study also showed improved duratio...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Announces Results from Phase 3 MAIA Study Showing Significant Overall Survival Benefits for Treatment with DARZALEX ® (daratumumab) in Patients with Newly Diagnosed Multiple Myeloma Who are Transplant Ineligible
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced overall survival (OS) results from the Phase 3 MAIA (NCT02252172) study showing the addition of DARZALEX® (daratumumab) to lenalidomide and dexamethasone (D-Rd) resulted in a statistically significant survival benefit over lenalidomide and dexamethasone (Rd) alone in patients with newly diagnosed multiple myeloma (NDMM) who were ineligible for autologous stem cell transplant (ASCT) and were treated to progression.[1] These data were featured in the European Hematology Association (EHA) 2021 Virtual Press Briefin...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

South Africa: Blood Donation Saves Lives but Few South Africans Are Regular Donors
[The Conversation Africa] Blood donation is a vital therapy for a number of life threatening conditions. South Africa needs around 810,000 units of blood every year. People needing blood transfusions include accident victims, those with anaemia and patients undergoing surgery. But less than 1% of South Africans are active blood donors, which means regular shortages of supply. Glenda Mary Davison, a medical scientist with a special interest in haematological malignancy, immunology and inflammation, unpacks the blood donation process (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 11, 2021 Category: African Health Source Type: news

Standard processes fail to follow up half of Microcytic anaemia patients correctly
Dr Janne Cadamuro, from the University Hospital of Salzburg in Austria, reviewed the diagnostic process in Laboratory Information Systems and found that 50% of Microcytic anaemia patients were not followed up at all or followed up correctly. (Source: mobihealthnews)
Source: mobihealthnews - June 11, 2021 Category: Information Technology Tags: < div class= entity entity-paragraphs-item paragraphs-item-enterprise-taxonomy about= typeof= > content /div Source Type: news

Vitamin B12 supplement: Two indications on your feet that you’re deficient in the nutrient
VITAMIN B12 supplements are taken to correct a nutritional deficiency that may not be related to what you eat. It's fairly common for older adults to acquire an autoimmune condition called pernicious anaemia. (Source: Daily Express - Health)
Source: Daily Express - Health - June 2, 2021 Category: Consumer Health News Source Type: news

Janssen Highlights Commitment to Advancing Transformative Innovations in Oncology with Scientific Updates from Deep, Diverse Pipeline and Portfolio at ASCO and EHA Virtual Scientific Programs
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 30 company-sponsored studies, including six oral presentations, will be featured during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, June 4-8. Janssen presentations will include new data and updates for both approved and investigational therapeutics that are being studied for the treatment of various solid tumors and blood cancers. Immediately following ASCO, additional data will be featured during the European Hematology Association (EHA) Virtual Congress, June 9-17. A ...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Reports New Data for BCMA CAR-T, Cilta-Cel, Showing Deep and Durable Responses in Patients with Relapsed or Refractory Multiple Myeloma
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data for ciltacabtagene autoleucel (cilta-cel), an investigational B-cell maturation antigen (BCMA)-directed CAR-T therapy, demonstrated sustained efficacy and durable responses in heavily pretreated patients with relapsed/refractory multiple myeloma (RRMM). Updated results from the Phase 1b/2 CARTITUDE-1 study (n=97) with a longer-term follow-up at a median of 18 months showed an overall response rate (ORR) of 98 percent, with 80 percent of patients achieving a stringent complete response (sCR), highlight...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Akebia and Otsuka Announce FDA Acceptance for Filing of New Drug Application for Vadadustat for the Treatment of Anemia Due to Chronic Kidney Disease in Adult Patients on Dialysis and Not on Dialysis
CAMBRIDGE, Mass. and TOKYO, June 1, 2021 /PRNewswire/ -- Akebia Therapeutics, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose of bettering the lives of people impacted by kidney disease, and its... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - June 1, 2021 Category: Drugs & Pharmacology Source Type: news

‘On That Edge of Fear’: One Woman’s Struggle With Sickle Cell Pain
Cures for a disease that mostly afflicts Black people seem near, but may come too late for Lisa Craig, who lives with an agony like knives stabbing her bones. (Source: NYT Health)
Source: NYT Health - May 30, 2021 Category: Consumer Health News Authors: John Eligon and William DeShazer Tags: Sickle Cell Anemia Pain-Relieving Drugs Chronic Condition (Health) Addiction (Psychology) Opioids and Opiates Race and Ethnicity Doctors Blood Black People Vanderbilt University Medical Center Source Type: news

Finding New Optimism In Those Pandemic Babies
Well hello! I’m so glad you’re here. A version of this article also appeared in theIt’s Not Just You newsletter.Sign up here to receive a new edition every Sunday. As always, you can send comments to me at: Susanna@Time.com. A slew of beloved friends have been having babies lately. I’m embarrassingly emotional about their arrival, or even just the news that they’re on their way. Knowing that this new crop of young ones will uncover delight in this bruised world is one of those ancient wonders. [time-brightcove not-tgx=”true”] It’s been a fractious and scary year, but these p...
Source: TIME: Health - May 30, 2021 Category: Consumer Health News Authors: Susanna Schrobsdorff Tags: Uncategorized It's Not Just You Source Type: news

Vitamin B12 deficiency: Two warning signs on your legs to watch out for
VITAMIN B12 deficiency is increasingly common in older adults, especially as people around the age of 60 are prone to developing pernicious anaemia. Here the condition is detailed in depth. (Source: Daily Express - Health)
Source: Daily Express - Health - May 27, 2021 Category: Consumer Health News Source Type: news

Long-Term ERLEADA ® (apalutamide) Patient-Reported Outcomes Data in Metastatic Castration-Sensitive Prostate Cancer Demonstrate Maintenance of Health-Related Quality of Life for Patients
May 26, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced patient-reported outcomes (PRO) data from the pre-specified final analysis of the Phase 3 TITAN study in patients with metastatic castration-sensitive prostate cancer (mCSPC). The TITAN study previously demonstrated statistically significant improvement in overall survival (OS) after a median follow-up of 44 months in patients receiving ERLEADA® plus androgen deprivation therapy (ADT).1 The new PRO data showed that the addition of ERLEADA® to ADT maintained patients’ health-related quality of lif...
Source: Johnson and Johnson - May 26, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Presents Updated Data on First-in-Class Talquetamab at ASCO Suggesting Deep and Durable Responses in Heavily Pretreated Patients with Multiple Myeloma
May 24, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today follow-up data from the MonumenTAL-1 Phase 1 first-in-human dose-escalation study of the investigational product talquetamab, the only off-the-shelf T-cell redirecting bispecific antibody in clinical development to target both GPRC5D, a novel multiple myeloma target, and CD3 on T-cells (NCT03399799).[1],[2],[3] With a median follow-up of more than six months, updated results in 30 patients with relapsed or refractory multiple myeloma treated with talquetamab by subcutaneous (SC) administration at the recommend...
Source: Johnson and Johnson - May 24, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

These Sisters With Sickle Cell Had Devastating, and Preventable, Strokes
Kyra and Kami never got a simple test that could have protected them. Their story exemplifies the failure to care for people with the disease, most of whom are Black. (Source: NYT Health)
Source: NYT Health - May 24, 2021 Category: Consumer Health News Authors: Gina Kolata and Ilana Panich-Linsman Tags: Stroke Tests (Medical) Preventive Medicine Ultrasonic Imaging and Sonograms Genetics and Heredity Transfusions Sickle Cell Anemia Black People Children and Childhood Race and Ethnicity Doctors National Institutes of Health Source Type: news

IMBRUVICA ® (ibrutinib)-Based Combination Regimen as a Fixed-Duration, First-Line Treatment for Chronic Lymphocytic Leukemia Demonstrates High Rates of Disease Control
May 19, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the fixed-duration cohort of the investigational Phase 2 CAPTIVATE study, showing that 95 percent of patients treated with combined IMBRUVICA® plus venetoclax were alive and progression-free at two years.[1] Deep remissions were seen across all subgroups, including patients with high-risk chronic lymphocytic leukemia (CLL).1 In addition, long-term data from the RESONATE-2 (PCYC-1115/1116) study will be presented, providing the longest follow-up Phase 3 data for any BTK inhibitor to date. Thes...
Source: Johnson and Johnson - May 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

FDA Approves New Treatment Option for Rare Anemia FDA Approves New Treatment Option for Rare Anemia
Pegcetacoplan (Empaveli) injection has been approved for use in adults with paroxysmal nocturnal hemoglobinuria (PNH).FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - May 19, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

EPO Treatment for Anemia Ups Fracture Risk in Dialysis EPO Treatment for Anemia Ups Fracture Risk in Dialysis
The use of ESAs to treat anemia in patients on dialysis increases hip fracture risk, and the higher the dose, the greater the risk.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 17, 2021 Category: Consumer Health News Tags: Nephrology News Source Type: news

Africa: Deworming Cuts Child Deaths, Saves Mothers
[Nation] Deworming during pregnancy reduces the risk of a child dying within the first four weeks after birth by 14 per cent and prevents a mother from developing anaemia, a new study has revealed. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 17, 2021 Category: African Health Source Type: news

Vitamin B12 deficiency: Six symptoms indicating you may be at risk of pernicious anaemia
VITAMIN B12 deficiency can be a commonplace for many. Even more so for anyone suffering with an autoimmune disease making absorbing the vitamin much harder. What are six symptoms indicating you may have this condition? (Source: Daily Express - Health)
Source: Daily Express - Health - May 16, 2021 Category: Consumer Health News Source Type: news

How Sickle Cell Trait in Black People Can Give the Police Cover
Sickle cell trait has been cited in dozens of police custody deaths ruled accidental or natural, even though the condition is benign on its own, a Times investigation found. (Source: NYT Health)
Source: NYT Health - May 15, 2021 Category: Consumer Health News Authors: Michael LaForgia and Jennifer Valentino-DeVries Tags: Black Lives Matter Movement Black People George Floyd Protests (2020) Police Brutality, Misconduct and Shootings Autopsies Prison Guards and Corrections Officers Genetics and Heredity Sickle Cell Anemia Sickle Cell Trait United States Source Type: news

Roxadustat Promise for Oral Treatment of Anemia in Kidney Disease Roxadustat Promise for Oral Treatment of Anemia in Kidney Disease
Headed to an FDA advisory committee assessment this summer, the oral anemia drug roxadustat, from the novel HIF-PHI drug class, adds to its efficacy and safety track record.Medscape Medical News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - May 12, 2021 Category: Transplant Surgery Tags: Nephrology News Source Type: news

Prevalence of anemia and its association with frailty, physical function and cognition in community-dwelling older adults: findings from the HOPE Study - Lee CT, Chen MZ, Yip CYC, Yap ES, Lee SY, Merchant RA.
OBJECTIVES: The prevalence of anemia and its impact on frailty and physical function amongst the multiethnic older populations in the Southeast Asian (SEA) countries are often not well studied. Singapore, a nation comprised of multiethnic communities, is o... (Source: SafetyLit)
Source: SafetyLit - May 8, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Vitamin B12 deficiency symptoms: Nine signs of the 'insidious' condition
A VITAMIN B12 deficiency is described as "insidious" by the National Institute for Health and Care Excellence . This is because it can lead to progressive symptoms of megaloblastic anaemia. (Source: Daily Express - Health)
Source: Daily Express - Health - May 7, 2021 Category: Consumer Health News Source Type: news

Injectafer (ferric carboxymaltose injection) Receives FDA Approval for Single Dose Option for the Treatment of Adult Patients with Iron Deficiency Anemia
BASKING RIDGE, N.J. and SHIRLEY, N.Y., May 6, 2021 /PRNewswire/ -- Daiichi Sankyo, Inc. and American Regent, Inc., a Daiichi Sankyo Group company, today announced that the U.S. Food and Drug Administration (FDA) has approved a... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - May 6, 2021 Category: Drugs & Pharmacology Source Type: news

What Is Anemia of Chronic Disease
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - May 4, 2021 Category: General Medicine Source Type: news

NCCN releases new patient guidelines on anemia and neutropenia
(National Comprehensive Cancer Network) New, resource from NCCN helps patients and caregivers recognize and understand blood cell production deficiencies such as anemia and neutropenia, to better participate in their care planning; available for free at NCCN.org/patientguidelines. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 3, 2021 Category: International Medicine & Public Health Source Type: news

Vadadustat for Anemia in Chronic Kidney Disease: Questions Remain Vadadustat for Anemia in Chronic Kidney Disease: Questions Remain
The HIF prolyl hydroxylase inhibitor shows efficacy in the treatment of anemia with chronic kidney disease, but in non-dialysis patients increased cardiovascular risks are observed.Medscape Medical News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - April 28, 2021 Category: Transplant Surgery Tags: Nephrology News Source Type: news

A Younger Adult With Rheumatoid Arthritis and COVID-19 Isolation
Mrs. R is a 47-year-old White woman who moved into the long-term care facility in 2018 when she needed more assistance than could be provided in her adult-care home. Her medical history is long and complicated: rheumatoid arthritis with multiple joint replacements, seizure disorder, right hemiparesis due to cerebrovascular accident, coronary artery disease with iron deficiency anemia, and rheumatic heart disease with aortic and mitral valve replacements. (Source: Caring for the Ages)
Source: Caring for the Ages - April 28, 2021 Category: Health Management Authors: Barbara Resnick, Paige Hector Tags: Interdisciplinary Team Case Studies Source Type: news

Improving the QOL for cats with renal disorders using drugs with minimal adverse reactions
(Japan Science and Technology Agency) To treat renal anemia for cats, veterinary medicine has only had an option of using erythropoietin (human EPO), that causes side effects. Kaneka Co. successfully developed feline (cat) erythropoietin (fEPO) with feline-derived amino acid sequences using transgenic chicken production technology based on the research results of Professor Shinji Iijima under JST's A-STEP program. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 28, 2021 Category: International Medicine & Public Health Source Type: news

Anemia discovery points to more effective treatment approaches
(University of Virginia Health System) A combination of inexpensive oral medications may be able to treat fatigue-inducing anemias caused by chronic diseases and inflammation, a new discovery suggests. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 27, 2021 Category: International Medicine & Public Health Source Type: news

Are There Developmental Changes in Platelet Function for Children?
Discussion While most people realize that each stage of a child’s life is different, there are some areas that people do not realize are different. For example, there are many laboratory values which are different based on the age because there are developmental changes. Within the hematopoietic system there are many developmental changes that are common such as hemoglobin and hematocrit. Others are less well known such as children have quantitatively less fibrinogen, but the activity is the same as adult fibrinogen. Platelets are an important part of both the primary and secondary hemostasis processes. They develop ...
Source: PediatricEducation.org - April 26, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Sapped: Exploring potential connections between devitalizing anemia and insomnia
(Cactus Communications) Genome wide analyses have revealed that MSEI, a gene linked with anemia is also associated with insomnia. The correlation between the two conditions, however, remains largely unexplored in adults. Thus, in a cross-sectional study, researchers assessed the relation between anemia and insomnia in a large Chinese cohort. Their findings, published in Chinese Medical Journal, suggest that anemia increases the risk of insomnia. Further studies can help elucidate the underlying molecular and physiological associations. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 22, 2021 Category: International Medicine & Public Health Source Type: news

Bypassing broken genes
(Penn State) A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases. The method involves inserting a new, fully functional copy of the gene that displaces the mutated gene. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 21, 2021 Category: International Medicine & Public Health Source Type: news

INDIGO Biosciences Expands Preclinical Portfolio for Anemia and...
Erythropoietin Receptor Assay Targets Red Blood Cell Development and Production(PRWeb April 20, 2021)Read the full story at https://www.prweb.com/releases/indigo_biosciences_expands_preclinical_portfolio_for_anemia_and_oncology_research/prweb17877148.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - April 20, 2021 Category: Pharmaceuticals Source Type: news