New Data Show Patients Treated with First-in-Class TREMFYA ® (guselkumab) Achieve Durable Efficacy Across Joint and Axial Symptoms of Active Psoriatic Arthritis Through Two Years
SPRING HOUSE, PENNSYLVANIA, June 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from Phase 3 studies demonstrating patients treated with TREMFYA® (guselkumab) achieved consistent, long-term efficacy through two years across the domains of active psoriatic arthritis (PsA) – including joint, skin, enthesitis,a dactylitis,b spinal pain and disease severityc endpoints – irrespective of baseline characteristics.1 Further analyses showed TREMFYA also provided patients with sustained improvements in measures of health-related quality of life (HRQoL), including fatigue, pain...
Source: Johnson and Johnson - June 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Iron deficiency: The everyday feeling which may intensify as the condition worsens
IF YOU have an iron deficiency a number of signs may crop up. If your diet is partly causing your iron deficiency anaemia, your GP will tell you what foods are rich in iron so you can eat more of them. (Source: Daily Express - Health)
Source: Daily Express - Health - June 1, 2022 Category: Consumer Health News Source Type: news

Janssen to Highlight Science, Innovation and Advances in Robust Oncology Portfolio and Pipeline Through More Than 60 Data Presentations at ASCO and EHA
RARITAN, N.J., May 31, 2022 — The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that new research and data from its robust oncology portfolio and pipeline of investigational therapies will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place June 3-7 in Chicago, and the European Hematology Association (EHA) 2022 Congress taking place in Vienna, Austria, June 9-12. More than 60 presentations from company-sponsored studies across the two congresses, including 14 oral presentations, will feature new data and updates for both approved and investigation...
Source: Johnson and Johnson - May 31, 2022 Category: Pharmaceuticals Source Type: news

European Commission Grants Conditional Approval of CARVYKTI ® (Ciltacabtagene Autoleucel), Janssen’s First Cell Therapy, for the Treatment of Patients with Relapsed and Refractory Multiple Myeloma
BEERSE, BELGIUM, 26 May 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the European Commission (EC) granted conditional marketing authorisation of CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) for the treatment of adults with relapsed and refractory multiple myeloma (RRMM) who have received at least three prior therapies, including an immunomodulatory agent (IMiD), a proteasome inhibitor (PI) and an anti-CD38 antibody, and have demonstrated disease progression on the last therapy. In December 2017, Janssen Biotech, Inc. (Janssen) entered into an exclusive worldwide license a...
Source: Johnson and Johnson - May 26, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Impact of Policy Changes for Anemia Care in Hemodialysis Examined
WEDNESDAY, May 25, 2022 -- Recommended erythropoietin-stimulating agent dosing changes for anemia care in adults undergoing hemodialysis led to lower erythropoietin-stimulating agent use and lower hemoglobin levels, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 25, 2022 Category: Pharmaceuticals Source Type: news

Episode 2: Are We Any Closer to Intestinal Gene Therapy in Crohn's Disease? Episode 2: Are We Any Closer to Intestinal Gene Therapy in Crohn's Disease?
Drs Peter Higgins and Judy Cho discuss recent success in sickle cell anemia and whether we ' re any closer to using intestinal gene therapy in Crohn ' s disease.Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 24, 2022 Category: Consumer Health News Tags: Gastroenterology InDiscussion Source Type: news

Kwaku Ohene-Frempong, Expert in Sickle Cell Disease, Dies at 76
When his baby boy was diagnosed with the illness, he made it his mission to combat it. He later took his expertise back to his native Ghana. (Source: NYT Health)
Source: NYT Health - May 19, 2022 Category: Consumer Health News Authors: Gina Kolata Tags: Ohene-Frempong, Kwaku Deaths (Obituaries) Sickle Cell Anemia Research Children ' s Hospital of Philadelphia Ghana Africa Source Type: news

Veterans Getting Closer to Justice at Camp Lejeune
Veterans and their families who were exposed to the contaminated drinking water at Marine Corps Base Camp Lejeune in North Carolina may soon find the justice they have been seeking for many years. The U.S. Senate is expected to soon pass legislation that delivers more comprehensive health care and benefits to veterans affected by all toxic exposure during their service. The Honoring Our PACT Act, a broad, nationwide plan already passed in the House of Representatives, will include the Camp Lejeune Justice Act of 2022, which focuses on four decades of water contamination at the base and the serious health problems it ...
Source: Asbestos and Mesothelioma News - May 19, 2022 Category: Environmental Health Authors: Sophia Clifton Tags: Veterans Source Type: news

Iron deficiency: The unsightly sign in your nails indicating you should speak to a doctor
IRON deficiency can have a number of signs, some of which can show up in your nails. Iron deficiency anaemia is a condition where blood lacks adequate healthy red blood cells, which are needed to carry oxygen to the body's tissues. (Source: Daily Express - Health)
Source: Daily Express - Health - May 18, 2022 Category: Consumer Health News Source Type: news

Targeting the Uneven Burden of Kidney Disease on Black Americans
New treatments aim for a gene variant causing the illness in people of sub-Saharan African descent. Some experts worry that focus will neglect other factors. (Source: NYT Health)
Source: NYT Health - May 17, 2022 Category: Consumer Health News Authors: Gina Kolata Tags: Kidneys Genetics and Heredity Black People Discrimination Research Drugs (Pharmaceuticals) Sleeping Sickness North Carolina Tests (Medical) Sickle Cell Anemia Source Type: news

Iron deficiency: Do you often have cold hands? It can signal iron deficiency anaemia
IRON deficiency anaemia is a condition where blood lacks adequate healthy red blood cells, which are needed to carry oxygen to the body's tissues. (Source: Daily Express - Health)
Source: Daily Express - Health - May 4, 2022 Category: Consumer Health News Source Type: news

What is in the Differential Diagnosis for Green, Blue or Violet Skin Conditions?
Discussion Acrocyanosis is commonly seen in the newborn period as the baby transitions to extra-uterine life. It appears as blue-purple coloration of the distal extremities which usually improves over several hours. Blue melanocytosis is also a common normal variant of skin color. It usually is seen on the posterior surface of the body around the spine and buttocks, but can also be on the upper parts of the extremities. It is a blue-black coloration that shows a normal skin undertone when palpated. This is the second in a short case series of differential diagnoses of colored skin conditions. An introduction to dermatologi...
Source: PediatricEducation.org - May 2, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

HbA1c Below the Reportable Range HbA1c Below the Reportable Range
This case report highlights the limitations of using HbA1c as a diagnostic tool in patients with certain conditions, including, as in this patient, hemolytic anemia.Laboratory Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 29, 2022 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Vitamin B12 deficiency: Unsteady movements 'may be subtle at first but usually increase'
A VITAMIN B12 or folate deficiency anaemia can cause a wide range of symptoms, according to the NHS. There are also some signs which may get gradually more clear, as a deficiency worsens. (Source: Daily Express - Health)
Source: Daily Express - Health - April 20, 2022 Category: Consumer Health News Source Type: news

US Food and Drug Administration Accepts New Drug Application for Daprodustat
Regulatory submission for the treatment of anaemia of chronic kidney disease based on the ASCEND phase III clinical trial programme, consisting of five trials that all met their primary efficacy and safety endpoints in non-dialysis and dialysis... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - April 19, 2022 Category: Drugs & Pharmacology Source Type: news