Estrogen Therapy Need Not Stop for Gender - Affirming Surgery
Authors find that perioperative venous thromboembolism rarely occurs, regardless of suspension of hormone therapy prior to surgery (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 19, 2021 Category: Cancer & Oncology Tags: Gynecology, Oncology, Pharmacy, Surgery, Journal, Source Type: news

Estrogen Therapy Need Not Stop for Gender-Affirming Surgery
TUESDAY, Jan. 19, 2021 -- For transgender and gender nonbinary (TGNB) patients undergoing primary vaginoplasty, perioperative venous thromboembolism (VTE) occurs rarely, regardless of whether hormone therapy is suspended prior to surgery, according... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 19, 2021 Category: Pharmaceuticals Source Type: news

The Menopause Transition: Signs, Symptoms, and Management The Menopause Transition: Signs, Symptoms, and Management
The transition to menopause brings hormonal changes and an array of disruptive symptoms. How are these symptoms best managed?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 19, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Testosterone Use in Adolescent Males Testosterone Use in Adolescent Males
Testosterone replacement is a considered treatment for adolescent boys who may require the hormone, but is often used off-label. When and how should it be used in this population?Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 19, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Gonadal and adrenal hormones interact with pubertal maturation to predict depressive symptoms in a group of high-school females - Chafkin JE, Yeager DS, O'Brien JM, Lee HY, McAfee CA, Josephs RA.
In this study, we addressed two questions: Are pubertal hormones associated with adolescent mental health? Might this association depend on pubertal development? We tested the hyp... (Source: SafetyLit)
Source: SafetyLit - January 15, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Plant roots sense soil compaction through restricted ethylene diffusion
We report that root growth in compacted soil is instead actively suppressed by the volatile hormone ethylene. We found that mutant Arabidopsis and rice roots that were insensitive to ethylene penetrated compacted soil more effectively than did wild-type roots. Our results indicate that soil compaction lowers gas diffusion through a reduction in air-filled pores, thereby causing ethylene to accumulate in root tissues and trigger hormone responses that restrict growth. We propose that ethylene acts as an early warning signal for roots to avoid compacted soils, which would be relevant to research into the breeding of crops re...
Source: ScienceNOW - January 14, 2021 Category: Science Authors: Pandey, B. K., Huang, G., Bhosale, R., Hartman, S., Sturrock, C. J., Jose, L., Martin, O. C., Karady, M., Voesenek, L. A. C. J., Ljung, K., Lynch, J. P., Brown, K. M., Whalley, W. R., Mooney, S. J., Zhang, D., Bennett, M. J. Tags: Botany, Genetics reports Source Type: news

Data Show More Women Are Freezing Their Eggs During the Pandemic, Defying Doctors ’ Expectations
If she found the right guy, Kari Arenberg could see herself having kids. But her work was never conducive to dating, let alone to freezing her eggs in hopes of leaving her options open. The 31-year-old event producer traveled constantly between New York City and Los Angeles, with long days lifting heavy boxes and running around venues. Then, in 2020, Arenberg was furloughed, and the egg-freezing process became, for the first time in her life, logistically possible. She moved in with her family in Chicago and visited a clinic. Soon she was giving herself as many as three shots a day to stimulate her ovaries, and visiting th...
Source: TIME: Health - January 13, 2021 Category: Consumer Health News Authors: Eliana Dockterman Tags: Uncategorized COVID-19 Source Type: news

Excess Weight During Pregnancy Tied to Fertility Issues in Sons
Being overweight may be tied to hormone imbalances that affect a male offspring ’s reproductive system, a new study suggests. (Source: NYT Health)
Source: NYT Health - January 13, 2021 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Obesity Weight Pregnancy and Childbirth Infertility Source Type: news

Entinostat Doesn't Overcome Endocrine Resistance in Breast Cancer Entinostat Doesn't Overcome Endocrine Resistance in Breast Cancer
The histone deacetylase inhibitor entinostat failed to overcome resistance to endocrine therapy in hormone receptor –positive, HER2-negative, advanced breast cancer in a phase 3 trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 13, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

What Is Hormone Therapy Used For
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 12, 2021 Category: General Medicine Source Type: news

How Can a Man Tell if He Has a Hormonal Imbalance?
Title: How Can a Man Tell if He Has a Hormonal Imbalance?Category: Diseases and ConditionsCreated: 1/12/2021 12:00:00 AMLast Editorial Review: 1/12/2021 12:00:00 AM (Source: MedicineNet Mens Health General)
Source: MedicineNet Mens Health General - January 12, 2021 Category: Primary Care Source Type: news

Mechanisms in the kidney that control magnesium and calcium levels discovered
(Massachusetts General Hospital) The gene KCTD1 directs production of a protein that functions in the kidney to maintain a normal balance of magnesium and calcium in blood. Loss of KCTD1 impairs the ability of the kidney to properly absorb magnesium and calcium from urine in the kidney, leading to abnormally low magnesium and calcium blood levels, thereby triggering the parathyroid glands to secrete excess parathyroid hormone that in turn leads to metabolic bone disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 12, 2021 Category: Biology Source Type: news

Study: New insights on the role of the MLL4 gene in Kabuki syndrome
(University at Buffalo) Research suggests that MLL4 controls the production of neurons that secrete growth hormone-releasing hormone (GHRH) in a part of the brain called the hypothalamus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 11, 2021 Category: International Medicine & Public Health Source Type: news

Levels of stress hormone in saliva of newborn deer fawns may predict mortality
(Penn State) The first-ever study of the levels of the stress hormone cortisol in the saliva of newborn white-tailed deer fawns yielded thought-provoking results that have Penn State researchers suggesting predation is not the only thing in the wild killing fawns. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 11, 2021 Category: Biology Source Type: news

How BBC's Mehreen Baig discovered her fitness plan could endanger her health
Mehreen Baig, pictured, was taking part in a BBC show The Truth About... Getting Fit At Home where she discovered her exercise regime has left her lacking some vital hormones. (Source: the Mail online | Health)
Source: the Mail online | Health - January 9, 2021 Category: Consumer Health News Source Type: news

Updates from the International Society of Endocrinology
Society for Endocrinology members are also members of the International Society of Endocrinology (ISE).ISE is committed to federating the endocrine community across the world as the“united nations of endocrinology”. They represent many large and smaller endocrine societies around the world with very different interests and levels of development.  They implement the initiatives outlined in the general assembly:   - to promote endocrine science and education internationally- to be a global advocate for endocrine prevention, diagnosis and management aro...
Source: Society for Endocrinology - January 6, 2021 Category: Endocrinology Source Type: news

New drug form may help treat osteoporosis, calcium-related disorders
(Purdue University) Purdue University innovators developed a stabilized form of human calcitonin, which is a peptide drug already used for people with osteoporosis. Researchers at Purdue created a prodrug form of the peptide hormone to increase its effectiveness as an osteoporosis treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 6, 2021 Category: International Medicine & Public Health Source Type: news

Sexual dysfunction hits some women harder than others as they age
(The North American Menopause Society (NAMS)) Sexual dysfunction often accompanies the menopause transition. Yet, not all women experience it the same. A new study identified the determinants that affect a woman's risk of sexual dysfunction and sought to determine the effectiveness of hormone therapy in decreasing that risk and modifying sexual behavior. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 6, 2021 Category: International Medicine & Public Health Source Type: news

Female mouse embryos actively remove male reproductive systems
NIEHS scientists discovered that a protein, not hormones, controls development of male reproductive organs in mice. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - January 6, 2021 Category: Environmental Health Source Type: news

Science Days fest showcases trainees and research across NIEHS
The 14th annual NIEHS Science Days celebrated scientific research across the institute, with a minisymposium on nuclear hormone receptors. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - January 6, 2021 Category: Environmental Health Source Type: news

The placenta — early mediator of environmental exposure
In a Keystone seminar, Jennifer Adibi, Sc.D., described how the placenta secretes hormones and serves as a buffer from the environment. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - January 6, 2021 Category: Environmental Health Source Type: news

Eighteenth year of Rodbell Lecture spotlights role of hormones in cancer
(read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - January 6, 2021 Category: Environmental Health Source Type: news

Study debunks theory that a hormone causes men's refractory period after sex
For decades, prolactin spikes have been blamed for the refractory period. But a new Portuguese study in mice found that changing levels of the hormone did not change how long they had to wait. (Source: the Mail online | Health)
Source: the Mail online | Health - January 5, 2021 Category: Consumer Health News Source Type: news

New clues to prostate cancer
(Flinders University) Australian research has identified a new mechanism in which prostate cancer cells can 'switch' character and become resistant to therapy. These findings, just published in Cell Reports, are an important development in unravelling how an aggressive subtype of prostate cancer, neuroendocrine prostate cancer (NEPC), develops after hormonal therapies. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 5, 2021 Category: Cancer & Oncology Source Type: news

US FDA Accepts Regulatory Submission from Pfizer and OPKO for Review of Somatrogon to Treat Pediatric Patients with Growth Hormone Deficiency
 NEW YORK& MIAMI--(BUSINESS WIRE) Monday, January 04, 2021 -- Pfizer Inc. (NYSE: PFE) and OPKO Health Inc. (NASDAQ: OPK) announced today that the US Food and Drug Administration (FDA) has accepted for filing the initial Biologics License... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - January 4, 2021 Category: Drugs & Pharmacology Source Type: news

Why do males have to wait for 'round 2'? The reason may be different from what we think
(Champalimaud Centre for the Unknown) New study refutes dominant theory claiming the hormone prolactin induces the male post-ejaculatory refractory period. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 4, 2021 Category: International Medicine & Public Health Source Type: news

Consumer Health: What is hypothyroidism?
Are you over 60, feeling fatigued and slowly gaining weight? These may be subtle signs of hypothyroidism, or underactive thyroid. Your thyroid is a butterfly-shaped gland located at the base of your neck. With hypothyroidism, your thyroid gland doesn't produce enough of certain crucial hormones. As a result, hypothyroidism affects all aspects of your metabolism [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - January 4, 2021 Category: Databases & Libraries Source Type: news

Best supplement for hair growth: Saw palmetto shown to combat hair thinning
BEST SUPPLEMENT for hair growth: Saw palmetto is a botanical extract with anti-androgenic properties, inhibiting the activity of male sex hormones. The activity of dihydrotestosterone has a role in male pattern hair loss. (Source: Daily Express - Health)
Source: Daily Express - Health - January 3, 2021 Category: Consumer Health News Source Type: news

Antibiotics banned in UK but fed to US animals ‘may undermine drugs for cancer, Covid and infections’: Ban on hormone beef and...
Even a ban on hormone beef and chlorinated chicken in UK-US trade deal would not be enough to protect consumers, report warns (Source: Reuters: Health)
Source: Reuters: Health - December 30, 2020 Category: Consumer Health News Source Type: news

Appetite-Regulating Hormones Lower After Sucrose Versus Glucose
WEDNESDAY, Dec. 30, 2020 -- Sucrose seems to be less efficient than glucose for signaling postprandial satiation, according to a study published online Dec. 10 in the Journal of Clinical Endocrinology& Metabolism. Alexandra G. Yunker, from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 30, 2020 Category: Pharmaceuticals Source Type: news

Too Few With Treatment-Resistant Hypertension Get Hormone Test Too Few With Treatment-Resistant Hypertension Get Hormone Test
Data from more than 25,000 US patients with treatment-resistant hypertension, all of whom qualified for assessment for primary aldosteronism, show just 1.6% were tested.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 29, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

With potential $4B Pfizer deal, 'upside-down' Peninsula biotech on hunt for more drugs
Myovant Sciences Ltd. will use the financial muscle generated by a potential $4.2 billion deal with drug giant Pfizer Inc. to beef up its pipeline of cancer and women's health drugs. The Pfizer compact, disclosed Monday, centers on Brisbane-based Myovant's potential blockbuster drug relugolix, which won Food and Drug Administration approval this month as the first oral hormone therapy for men with advanced prostate cancer. Myovant's stock climbed as high as $30.90 per share M onday — a new 52-week… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - December 28, 2020 Category: Biotechnology Authors: Ron Leuty Source Type: news

With potential $4B Pfizer deal, 'upside-down' Peninsula biotech on hunt for more drugs
Myovant Sciences Ltd. will use the financial muscle generated by a potential $4.2 billion deal with drug giant Pfizer Inc. to beef up its pipeline of cancer and women's health drugs. The Pfizer compact, disclosed Monday, centers on Brisbane-based Myovant's potential blockbuster drug relugolix, which won Food and Drug Administration approval this month as the first oral hormone therapy for men with advanced prostate cancer. Myovant's stock climbed as high as $30.90 per share M onday — a new 52-week… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - December 28, 2020 Category: American Health Authors: Ron Leuty Source Type: news

Study: Too few with treatment-resistant high blood pressure tested for hormone disorder
Fewer than 2% of people with treatment-resistant high blood pressure are checked for a hormone disorder that can drive blood pressure higher, a study published Monday by the Annals of Internal Medicine found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 28, 2020 Category: Consumer Health News Source Type: news

With potential $4 billion Pfizer deal, 'upside-down' Peninsula biotech on hunt for more drugs
Myovant Sciences Ltd. will use the financial muscle generated by a potential $4.2 billion deal with drug giant Pfizer Inc. to beef up its pipeline of cancer and women's health drugs. The Pfizer compact, disclosed Monday, centers on Brisbane-based Myovant's potential blockbuster drug relugolix, which won Food and Drug Administration approval this month as the first oral hormone therapy for men with advanced prostate cancer. Myovant's stock climbed as high as $30.90 per share M onday — a new 52-week… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - December 28, 2020 Category: Biotechnology Authors: Ron Leuty Source Type: news

With potential $4 billion Pfizer deal, 'upside-down' Peninsula biotech on hunt for more drugs
Myovant Sciences Ltd. will use the financial muscle generated by a potential $4.2 billion deal with drug giant Pfizer Inc. to beef up its pipeline of cancer and women's health drugs. The Pfizer compact, disclosed Monday, centers on Brisbane-based Myovant's potential blockbuster drug relugolix, which won Food and Drug Administration approval this month as the first oral hormone therapy for men with advanced prostate cancer. Myovant's stock climbed as high as $30.90 per share M onday — a new 52-week… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - December 28, 2020 Category: American Health Authors: Ron Leuty Source Type: news

Toxic Metals Might Affect Pregnancy, Study Finds
MONDAY, Dec. 28, 2020 -- Exposure to metals may disrupt pregnant women's hormones and boost the odds of complications such as preeclampsia, preterm birth and low birth weight, according to a new study. Metals such as nickel, arsenic, cobalt and lead... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 28, 2020 Category: General Medicine Source Type: news

Can Hormonal Imbalance Cause Weight Gain?
Title: Can Hormonal Imbalance Cause Weight Gain?Category: Diseases and ConditionsCreated: 12/24/2020 12:00:00 AMLast Editorial Review: 12/24/2020 12:00:00 AM (Source: MedicineNet Womens Health General)
Source: MedicineNet Womens Health General - December 24, 2020 Category: OBGYN Source Type: news

Gender Surgical Outcomes Differ Following Puberty Suppression Gender Surgical Outcomes Differ Following Puberty Suppression
"It [puberty supression] also gives adolescents the time needed to explore their gender identity prior to beginning irreversible cross-sex hormone (CSH) treatment," Tim C. van de Grift, MD, PhD.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 23, 2020 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Periodontitis, erectile dysfunction, reproductive hormones and semen quality: A systematic review
ConclusionThe results of this systematic review revealed a significant association between periodontitis and ED, although the responsible mechanisms remain unclear. The potential associations between sex hormone levels, semen quality and periodontitis are yet to be demonstrated. In order to improve patient management, dentists and physicians need to be aware of the association between male sexual health problems and periodontitis. (Source: Dental Technology Blog)
Source: Dental Technology Blog - December 23, 2020 Category: Dentistry Source Type: news

New oral hormone drug for prostate cancer
The Food and Drug Administration has approved the use of a new oral hormone therapy drug, Relugolix, for treating advanced prostate cancer in men.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 22, 2020 Category: Endocrinology Source Type: news

Heavy metal exposure during pregnancy associated with birth complications
According to a study in the journalEnvironmental International, exposure to heavy metals during pregnancy may alter hormonal balances and lead to preterm births, low birth weight and preeclampsia in women.News Medical (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 22, 2020 Category: Endocrinology Source Type: news

FDA Approves First Oral Hormone Therapy for Advanced Prostate Cancer
MONDAY, Dec. 21, 2020 -- Orgovyx (relugolix) is now approved to treat advanced prostate cancer and is the first oral hormone therapy approved for this indication, the U.S. Food and Drug Administration announced Friday. As opposed to currently... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 21, 2020 Category: Pharmaceuticals Source Type: news

Effects of testosterone therapy on constructs related to aggression in transgender men: a systematic review - Kristensen TT, Christensen LL, Frystyk J, Glintborg D, T'sjoen G, Roessler KK, Andersen MS.
BACKGROUND: Transgender men are assigned female sex at birth, but identify as men. The anabolic and androgenic sex hormone testosterone has been positively associated with aggression. Therefore, transgender men are warned of increasing aggression when init... (Source: SafetyLit)
Source: SafetyLit - December 21, 2020 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news

Hair loss treatment: Pumpkin seed oil promotes hair growth by blocking hormone behind it
BEST hair loss treatment: Herbal remedies are increasingly recognised as credible treatments for hair loss. Pumpkin seed oil has been shown to target DHT - a key contributor to hair loss. (Source: Daily Express - Health)
Source: Daily Express - Health - December 21, 2020 Category: Consumer Health News Source Type: news

Exposure to metals can impact pregnancy
(Rutgers University) Exposure to metals such as nickel, arsenic, cobalt and lead may disrupt a woman's hormones during pregnancy, according to a Rutgers study. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 21, 2020 Category: International Medicine & Public Health Source Type: news

Silkworm's brain determines diapause by thermal information
In this study scientists at Shinshu University et al. have elucidated that the neuropeptide corazonin regulates the release of the diapause hormone. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 21, 2020 Category: Biology Source Type: news

Hormone metabolites found in poop give researchers new insight into whale stress
(Oregon State University) Poop samples are an effective, non-invasive tool for monitoring gray whale reproduction, stress and other physiological responses. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 21, 2020 Category: International Medicine & Public Health Source Type: news

Type 2 diabetes: The four warning signs your blood sugar levels are too high
TYPE 2 DIABETES occurs when the body is unable to use insulin - the hormone responsible for regulating blood sugar levels - properly. Why does this happen? And what are the signs of the condition? (Source: Daily Express - Health)
Source: Daily Express - Health - December 19, 2020 Category: Consumer Health News Source Type: news

FDA OKs First Oral Hormone Tx for Advanced Prostate Cancer FDA OKs First Oral Hormone Tx for Advanced Prostate Cancer
Relugolix is an oral form of androgen deprivation therapyFDA Approvals (Source: Medscape Urology Headlines)
Source: Medscape Urology Headlines - December 18, 2020 Category: Urology & Nephrology Tags: Hematology-Oncology News Source Type: news