Dr MAI THI NGUYEN-KIM on the hidden chemistry that rules our lives and loves
Dr MAI THI NGUYEN-KIM: Our bodies are full of chemicals - we call them 'hormones' and 'neurotransmitters' - and the way they interact with our cells determines our health and behaviour. (Source: the Mail online | Health)
Source: the Mail online | Health - April 20, 2021 Category: Consumer Health News Source Type: news

Janssen Provides Update on Phase 3 ACIS Study in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with ERLEADA ® (apalutamide) and ZYTIGA® (abiraterone acetate) Plus Prednisone Combination
RARITAN, N.J., April 19, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that regulatory submissions based on the Phase 3 ACIS study, which evaluated the combination of ERLEADA® (apalutamide) and ZYTIGA® (abiraterone acetate) plus prednisone in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC), will not be pursued. As presented at the American Society of Clinical Oncology’s Genitourinary (ASCO GU) Cancers Symposium in February 2021, the ACIS study met its primary endpoint of radiographic progression-free survival (rPFS); ho...
Source: Johnson and Johnson - April 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Transgender Hormone Therapy Linked to Blood Pressure Changes Transgender Hormone Therapy Linked to Blood Pressure Changes
Blood pressure elevations in transgender males and a subset of transgender females are seen before and soon after gender-affirming hormone therapy initiation.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 19, 2021 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

Gender-Affirming Hormone Therapy Tied to Systolic BP Changes
MONDAY, April 19, 2021 -- Within two to four months of starting gender-affirming hormone therapy (GAHT), transfeminine adults have lower mean systolic blood pressure and transmasculine adults have higher mean systolic blood pressure, according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 19, 2021 Category: Pharmaceuticals Source Type: news

Factors Identified to Help Predict Age at Menopause
MONDAY, April 19, 2021 -- Higher levels of estradiol and follicle-stimulating hormone, irregular menstrual cycles, and symptoms of menopause are strong indicators that a woman is approaching menopause, according to a study published online April 12... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 19, 2021 Category: Pharmaceuticals Source Type: news

Hormone Treatments May Raise Blood Pressure in Transgender People
MONDAY, April 19, 2021 -- Monitoring blood pressure is important for transgender people, according to new research, which found changes in systolic blood pressure after the start of gender-affirming hormone therapy. Transgender men and transgender... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 19, 2021 Category: General Medicine Source Type: news

Gender-affirming hormone therapy may increase risk of high blood pressure
(Beth Israel Deaconess Medical Center) In the largest and longest observational study of its kind, physician-researchers from Beth Israel Deaconess Medical Center (BIDMC) found that gender-affirming hormone therapy (GAHT) was associated with blood pressure changes in both transgender men and women. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 19, 2021 Category: International Medicine & Public Health Source Type: news

Estrogen status - not sex - protects against heightened fear recall
(Elsevier) A new study shows that markers of fear recall differ between men and women, but in a hormone-dependent manner. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 15, 2021 Category: International Medicine & Public Health Source Type: news

Trillions of ‘Brood X’ Cicadas Are About to Emerge Across the U.S. to Sing, Mate and Die. Here’s What to Expect
This coming May, millions of people around the United States will have front-row seats to an extraordinary entomological event: Trillions of Brood X cicadas across 15 states will emerge almost synchronously after having spent the last 17 years underground. The males will take up elevated positions, each buzzing as loud as a lawnmower to attract females. After mating, the adult cicadas will die off en masse just about as quickly as they arrived—likely sometime in late June or July—while their offspring tunnel underground, not to emerge until 2038, when the dance will begin anew. Annual, or “dog day,”...
Source: TIME: Science - April 14, 2021 Category: Science Authors: Rebecca Katzman Tags: Uncategorized animals Environment News Source Type: news

Sitting in a tin can: why sci-fi films are finally telling astronaut life like it is
New Netflix drama Stowaway is the latest in a crop of movies that suggests space travel is more random death and boredom than warp speed nineAnybody who fancies watching a new science fiction film this month can count their lucky stars. A Netflix drama,Stowaway, features Anna Kendrick, Toni Collette and Daniel Dae Kim as a trio of astronauts who are on their way to Mars when they discover that an unfortunate launch-plan engineer, Shamier Anderson, is still onboard. The trouble is, there is only enough oxygen for three of them. American viewers can also see Voyagers (due for release in Britain in July), in which 30 hormonal...
Source: Guardian Unlimited Science - April 14, 2021 Category: Science Authors: Nicholas Barber Tags: Film Science fiction and fantasy films Space Culture The Martian George Clooney Brad Pitt Source Type: news

If a pill could ease your heartbreak or enhance your relationship, would you take it?
Love potions are the stuff of fiction, but in recent years, a field of research has emerged that is exploring how to use MDMA, antidepressants and other drugs to manipulate the neurological and hormonal processes related to falling in and out of love. (Source: CBC | Health)
Source: CBC | Health - April 14, 2021 Category: Consumer Health News Tags: Radio/Ideas Source Type: news

This Femtech Company Is Pioneering Mucus Engineering As A New Alternative To Hormonal Birth Control
Cirqle Biomedical is a startup pioneering mucus engineering as a new alternative to hormonal birth control, based in Copenhagen, and its team recently demonstrated the first novel and effective approach to contraception since hormonal therapy was introduced more than 60 years ago. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - April 14, 2021 Category: Pharmaceuticals Authors: Marija Butkovic, Contributor Tags: ForbesWomen /forbeswomen Leadership /leadership Innovation /innovation Healthcare /healthcare Source Type: news

Dr. Anthony Fauci on what the Johnson & Johnson vaccine reactions could mean for women
Fauci said the adverse reactions in six women could suggest that it's hormonal. (Source: Reuters: Health)
Source: Reuters: Health - April 14, 2021 Category: Consumer Health News Source Type: news

New Skoltech sensor tracks 'stress hormone' in real time
(Skolkovo Institute of Science and Technology (Skoltech)) Skoltech researchers have developed a fluorescence-based sensor prototype for continuous detection of cortisol concentrations in real time, which can help monitor various health conditions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2021 Category: International Medicine & Public Health Source Type: news

< a href= " /news-events/nih-research-matters/how-stress-causes-hair-loss " > How stress causes hair loss < /a >
Researchers found that a stress hormone impairs stem cells necessary for hair growth in mice. The findings suggest potential ways to treat hair loss caused by chronic stress. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 13, 2021 Category: Consumer Health News Source Type: news

Hair loss treatment: Finasteride blocks an enzyme in DHT to increase hair growth
Hair loss treatment backed by science will often be the best bet when choosing the best remedy. Finasteride was shown in studies to block an enzyme that converts the male hormone testosterone into dihydrotestosterone . (Source: Daily Express - Health)
Source: Daily Express - Health - April 9, 2021 Category: Consumer Health News Source Type: news

Hyperglycemia, Insulin, and Insulin Resistance in Sepsis, The American journal of the medical sciences
Critically ill patients frequently have hyperglycemia. This event may reflect severe stress with an imbalance between anabolic hormones and catabolic hormones. Alternatively, it may reflect alterations in either insulin levels or insulin function. Insulin is a pleiotropic hormone with multiple important metabolic effects. In patients with sepsis, insulin levels are increased but insulin sensitivity is decreased. However, there is variability in insulin sensitivity, and this creates variability in glucose levels and insulin requirements and increases the frequency of hypo- and hyperglycemia. The factors that influence insul...
Source: Current Awareness Service for Health (CASH) - April 9, 2021 Category: Consumer Health News Source Type: news

Roundup:'On-the-spot' COVID-19 test receives CE Mark, Thriva launches women's hormones test and more briefs
Also, startup creates wearable tech to tackle head injuries in sport. (Source: mobihealthnews)
Source: mobihealthnews - April 9, 2021 Category: Information Technology Tags: Emerging Technologies, Technology Source Type: news

Balancing between build-up and break-down of bone
(Osaka University) Researchers at Osaka University have shown that SLPI, a secretory leukocyte protease inhibitor, coordinates the mutually contradictory actions of parathyroid hormone (PTH) on bone. They revealed the genetic mechanisms and molecular pathways whereby SLPI promotes osteoblast activity to augment bone mass and showed how osteoblasts interact with osteoclasts to subdue bone resorption. This knowledge will inform clinical usage of anabolic PTH in osteoporosis as well as promote development of innovative drugs. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 9, 2021 Category: Biology Source Type: news

Scientists identify new differences between the sexes in age-related changes to brain stem cells
(International Society for Stem Cell Research) Data suggest that ageing-related changes to stem cells and blood vessels in the brain are more pronounced in male animals. Possible causes for these differences by sex, such as hormonal or genetic influences and their impact on brain function and disease related to ageing, require further investigation. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 8, 2021 Category: Biology Source Type: news

Consumer Health: Treating pituitary tumors
The pituitary is a small, bean-shaped gland at the base of your brain, behind your nose and between your ears. Despite its small size, the pituitary gland influences nearly every part of your body. The hormones it produces help regulate important functions, such as growth, blood pressure and reproduction. Pituitary tumors are abnormal growths that [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 8, 2021 Category: Databases & Libraries Source Type: news

Bilateral retinal toxicity as a result of poisoning with pure iodine - Esra BC, Yasin SG.
Iodine is an essential mineral that is necessary for the synthesis of thyroid hormones, which can cause many diseases in the body. The application of adding potassium iodate to table salts started in Turkey in 1998. High doses of iodate cause retinal toxic... (Source: SafetyLit)
Source: SafetyLit - April 7, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

New biosensor makes control hormone auxin visible in cells
(Universit ä t Bayreuth) The hormone auxin is of central importance for the development of plants. Scientists at the University of Bayreuth and the Max Planck Institute for Developmental Biology in T ü bingen have now developed a novel sensor that makes the spatial distribution of auxin in the cells of living plants visible in real time. The sensor opens up completely new insights into the inner workings of plants for researchers. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 7, 2021 Category: Biology Source Type: news

Major research award goes to U of T scientist for revolutionizing diabetes treatment
(University of Toronto) Daniel Drucker of the University of Toronto has been jointly awarded a 2021 Gairdner International Award for research that has helped revolutionize treatments for type 2 diabetes, obesity and intestinal disorders. He receives the honour with Joel Habener of Harvard University and Massachusetts General Hospital, and Jens Juul Holst of the University of Copenhagen, for research on glucagon-like peptides - hormones that control insulin and glucagon, which work to balance sugar levels throughout the body. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 7, 2021 Category: International Medicine & Public Health Source Type: news

Tucker presses Arkansas gov over veto of bill banning gender hormones, surgeries for transgender youth
Arkansas Republican Gov. Asa Hutchinson defended his decision to veto legislation that would have made his state the first to ban... (Source: Reuters: Health)
Source: Reuters: Health - April 7, 2021 Category: Consumer Health News Source Type: news

Benefits and Risks of Menopausal HT Among Women 50-59 Benefits and Risks of Menopausal HT Among Women 50-59
This report analyzes additional years of follow-up from the Women's Health Initiative hormone therapy trials, with a focus on participants 50-59 years of age. Does the new data change recommendations?American Journal of Epidemiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 6, 2021 Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news

New research evaluates effects of pregnancy-related hormones on hepatic drug-metabolizing enzymes
(Rana Healthcare Solutions LLC) BioIVT Senior Scientist Raju Khatri, MS, PhD, DABT, will discuss his recently published research which shows how pregnancy-related hormones (PRH) are important regulators of hepatic cytochrome P450 (CYP) enzyme expression and function. Using a sandwich-cultured human hepatocyte model, Dr. Khatri's research team showed that exposure to PRH can significantly increase concentrations of CYP3A4 and other CYPs, resulting in a dose-dependent increase in nifedipine metabolism. Nifedipine is often prescribed during pregnancy to manage hypertensive disorder. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 6, 2021 Category: International Medicine & Public Health Source Type: news

Maternal stress in conception linked to higher chance of female foetus
(University of Granada) Scientists from the University of Granada have analysed the levels of cortisol (a steroid hormone that is released in response to stress) in the hair of pregnant women in the period spanning from before conception to week 9 of their pregnancy, to determine whether there was any link to the sex of the baby (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 6, 2021 Category: International Medicine & Public Health Source Type: news

Study links prenatal phthalate exposure to altered information processing in infants
(University of Illinois at Urbana-Champaign, News Bureau) Exposure to phthalates, a class of chemicals widely used in packaging and consumer products, is known to interfere with normal hormone function and development. Now researchers have found evidence linking pregnant women's exposure to phthalates to altered cognitive outcomes in their infants. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 6, 2021 Category: International Medicine & Public Health Source Type: news

Leptin puts the brakes on eating via novel neurocircuit
(Elsevier) A new study in mice describes novel neurocircuitry between midbrain structures that control feeding behaviors that are under modulatory control by leptin, a hormone made by body fat. Since the discovery of leptin in the 1990s, researchers have wondered how leptin can suppress appetite. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 6, 2021 Category: International Medicine & Public Health Source Type: news

Doctors eye new drug that could end the monthly agony for women with endometriosis
A hormone-free device, which would circumvent many of the side-effects associated with existing options, is being suggested as a new treatment for endometriosis. (Source: the Mail online | Health)
Source: the Mail online | Health - April 6, 2021 Category: Consumer Health News Source Type: news

Traumatic brain injury as frequent cause of hypopituitarism and growth hormone deficiency: epidemiology, diagnosis, and treatment - Gasco V, Cambria V, Bioletto F, Ghigo E, Grottoli S.
Traumatic brain injury (TBI)-related hypopituitarism has been recognized as a clinical entity for more than a century, with the first case being reported in 1918. However, during the 20(th) century hypopituitarism was considered only a rare sequela of TBI.... (Source: SafetyLit)
Source: SafetyLit - April 5, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

New doping test distinguishes natural hormones from synthetic drugs
A new technique to test for doping is being unveiled Monday that aims to ensnare athletes using designer performance-enhancing drugs that are difficult to distinguish from natural molecules. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 5, 2021 Category: Consumer Health News Source Type: news

CHILD TORTURE PAYS: Planned Parenthood now in the business of chemically castrating adolescents and neutering male children
(Natural News) Of all the wonderful women’s healthcare services offered at Planned Parenthood, none can compare to their latest healthcare endeavor: neutering male children. That’s right, Planned Parenthood is now preying on adolescent boys to convince them to take synthetic hormones. Planned Parenthood isn’t content with their current operation — pressuring women to go under... (Source: NaturalNews.com)
Source: NaturalNews.com - April 4, 2021 Category: Consumer Health News Source Type: news

Obesity may affect puberty timing and hormones in girls
Study shows girls with excess body fat developed mature breasts more slowly, but started their period sooner than girls with normal weight. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - April 2, 2021 Category: Environmental Health Source Type: news

Preterm birth, prolonged labor influenced by progesterone balance
Novel research in mice uncovers hormone regulation needed in late pregnancy, opens door for therapy. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - April 2, 2021 Category: Environmental Health Source Type: news

High Stress Hormone Levels Halt Mouse Fur Growth
Corticosterone interferes with signaling in the skin that normally activates hair follicle stem cells, possibly explaining the link between stress and hair loss. (Source: The Scientist)
Source: The Scientist - April 1, 2021 Category: Science Tags: News & Opinion Source Type: news

I thought I was over my Catholic guilt about being gay. Maybe I was wrong? | Antoun Issa
An adolescence of shame about being LGBTQ+ can have lingering effects on our behaviour that stretch well into adulthoodGuilt and shame can be addictive. In certain religious and traditional contexts, it can even be venerated, honoured – the requisite emotion that subdues human ego and maintains humility at the feet of a far higher power. But it can also leave an indelible stain on our character, our personality, and our mental health that endures for years, particularly for those brought up in such conservative environments whe re guilt and shame were measurements of our own self-worth.“It’s good to cry w...
Source: Guardian Unlimited Science - April 1, 2021 Category: Science Authors: Antoun Issa Tags: LGBT rights Catholicism Religion Christianity Psychology Source Type: news

Low-calorie diet and mild exercise improve survival for young people with leukemia
In some cancers, including leukemia in children and adolescents, obesity can negatively affect survival outcomes. Obese young people with leukemia are 50% more likely to relapse after treatment than their lean counterparts.Now,a study led by researchers at UCLA and Children’s Hospital Los Angeles has shown that a combination of modest dietary changes and exercise can dramatically improve survival outcomes for those with acute lymphoblastic leukemia, the most common childhood cancer.The researchers found that patients who reduced their calorie intake by 10% or more and adopted a moderate exercise program imm...
Source: UCLA Newsroom: Health Sciences - April 1, 2021 Category: Universities & Medical Training Source Type: news

Exposure To Harmful Chemicals In Plastics May Increase Risk Of Postpartum Depression, Study Finds
Endocrine-disrupting chemicals may influence hormonal shifts during pregnancy as well as contribute to postpartum depression, according to a small study published in the Endocrine Society's Journal of Clinical Endocrinology& Metabolism. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - April 1, 2021 Category: Pharmaceuticals Authors: Misha Gajewski, Contributor Tags: Healthcare /healthcare Innovation /innovation Science /science Source Type: news

Trans teenagers fear Alabama push to outlaw gender treatment
Transgender youth and their parents are speaking out against an Alabama bill that would criminalize medical professionals who prescribe hormone treatments to transgender minors (Source: ABC News: Health)
Source: ABC News: Health - March 31, 2021 Category: Consumer Health News Tags: Health Source Type: news

The happiness factor
To be or not to be, that is the question? The opening line of Hamlet’s soliloquy is a memorable piece that you probably remember from school days. But it is the beginning of a personal consideration about the merits of suicide; it’s no wonder the play is one of Shakespeare’s tragedies. I like to think that perhaps Will could have improved it just a little by the addition of one simple word. To be happy or not to be happy, now that is an even more interesting question? Perhaps in changing the tone of the opening line Hamlet might have changed his fate and so turned tragedy into something altogether lighter...
Source: The Hysterectomy Association - March 31, 2021 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Happiness Source Type: news

Arkansas Senate OKs Ban on Treatments for Transgender Youth Arkansas Senate OKs Ban on Treatments for Transgender Youth
The bill would prohibit doctors from providing gender-confirming hormone treatment or surgery to minors, or from referring them to other providers for the treatment.Associated Press (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 30, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Pediatrician provides a voice for youth traumatized by family separation
Growing up in Brentwood,Dr. Elizabeth Barnert was raised to be acutely aware of two versions of Los Angeles — one of privilege and one of social injustice.Her psychiatrist father instilled in his daughter a love of science and big-picture thinking. Her mother, who fled Castro ’s Cuba alone at 15, worked as a social worker counseling troubled high-school students, many of them first-generation Americans who butted heads with their immigrant parents over issues like cultural identity and gangs.“My father took me to the library every Saturday and taught me the importance of life-long learning,” said Ba...
Source: UCLA Newsroom: Health Sciences - March 29, 2021 Category: Universities & Medical Training Source Type: news

Many Unknowns on Fertility Preservation in Transgender Patients Many Unknowns on Fertility Preservation in Transgender Patients
The effect of gender-affirming hormones on fertility in transgender people is still a big unknown, and those embarking upon such treatment need good counseling around fertility preservation, say experts.Medscape Medical News (Source: Medscape Pediatrics Headlines)
Source: Medscape Pediatrics Headlines - March 29, 2021 Category: Pediatrics Tags: Diabetes & Endocrinology News Source Type: news

Weighing the Use of Growth Hormones for Children
New research has linked growth hormone treatment to serious adverse health effects years later. (Source: NYT Health)
Source: NYT Health - March 29, 2021 Category: Consumer Health News Authors: Jane E. Brody Tags: Height (Stature) Children and Childhood Human Growth Hormone Hormones Parenting Endocrine Gland Source Type: news

Common medications contain animal byproducts, study finds
(American Osteopathic Association) Common medications, including widely used blood thinners and hormones, are often derived from animal byproducts and prescribed without consulting the patient about their beliefs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2021 Category: International Medicine & Public Health Source Type: news

Shanna Swan: 'Most couples may have to use assisted reproduction by 2045'
The professor of environmental medicine explains how chemicals in plastics are causing our fertility to decline – and what we can do about itShanna Swan is a professor of environmental medicine and public health at Mount Sinai school of medicine in New York City, studying fertility trends. In 2017 she documented how average sperm counts among western men havemore than halved in the past 40 years.Count Down is her new book.You ’ve spent more than20 years examining the effects of hormone disrupting chemicals on reproductive health. Are you now sounding the alarm?I am directly speaking to this hidden problem peopl...
Source: Guardian Unlimited Science - March 28, 2021 Category: Science Authors: Zo ë Corbyn Tags: Fertility problems Reproduction Biology Science Health Environment Source Type: news

How testosterone provided the cure for businesswoman's low libido and menopausal brain fog
Michelle Burgess' monthly hormonal migraines were lingering far longer than normal and she no longer had enthusiasm for anything - until she was prescribed HRT and testosterone. (Source: the Mail online | Health)
Source: the Mail online | Health - March 27, 2021 Category: Consumer Health News Source Type: news

What Are The Links Between Hormonal Birth Control & Blood Clots?
Some have said that the same concern given to the links between the Covid-19 vaccine and blood clots should be focused on hormonal contraception and women ’s health. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 27, 2021 Category: Pharmaceuticals Authors: Alice Broster, Contributor Tags: Healthcare /healthcare Innovation /innovation Source Type: news