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Developing a New Score: How Machine Learning Improves Risk Prediction
Composite risk scores have been used for decades to identify disease risk and health status in the general population. However, current approaches often fail to identify people who would benefit from intervention or recommend unnecessary intervention. Machine learning promises to improve accuracy, ensuring targeted treatment for patients that need it and reducing unnecessary intervention. Framingham Risk Score, the gold standard for predicting the likelihood of heart disease, predicts hospitalizations with about 56% accuracy. It uses factors such as age, gender, smoking, cholesterol levels, and systolic blood pre...
Source: MDDI - November 17, 2017 Category: Medical Devices Authors: Heather R. Johnson Tags: R & D Source Type: news

Maxidex Ointment (Dexamethasone Sodium Phosphate Ophthalmic) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 15, 2017 Category: Drugs & Pharmacology Source Type: news

Nexium I.V. (Esomeprazole Sodium) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 14, 2017 Category: Drugs & Pharmacology Source Type: news

HealthWatch: New High Blood Pressure Guidelines
BOSTON (CBS) – For the first time in more than a decade, the American Heart Association is changing the guidelines for high blood pressure. This means nearly half the US adult population is living with hypertension and at an increased risk of heart disease and stroke. Charles Cronenweth has been working to lower his blood pressure for the last 10 years. Tens of millions more Americans will soon be learning they also have hypertension. The American Heart Association and American College of Cardiology are now defining a top reading of 130 or more or a bottom reading of 80 or more as high blood pressure. The o...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 14, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Healthwatch Local News Seen On WBZ-TV Syndicated Local American College of Cardiology American Heart Association Dr. Mallika Marshall High Blood Pressure Source Type: news

Sodium Bicarbonate, Acetylcysteine Don't Prevent Kidney Injury After Angiography
Neither sodium bicarbonate nor acetylcysteine appears to reduce risk for acute kidney injury in high-risk patients undergoing angiography, according to a randomized trial published... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 13, 2017 Category: Primary Care Source Type: news

No Benefit From Bicarbonate, Acetylcysteine Postangiography No Benefit From Bicarbonate, Acetylcysteine Postangiography
In the PRESERVE trial, neither intravenous sodium bicarbonate nor oral N-acetylcysteine significantly reduced adverse outcomes compared with sodium chloride or placebo.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 13, 2017 Category: Cardiology Tags: Cardiology News Source Type: news

Sodium Oxybate Promising for Parkinson ’ s, Daytime Sleepiness
Improvements in subjective sleep quality, objectively measured slow - wave sleep duration (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 8, 2017 Category: Respiratory Medicine Tags: Family Medicine, Geriatrics, Internal Medicine, Neurology, Pharmacy, Pulmonology, Journal, Source Type: news

Nithiodote (Sodium Nitrite Injection for Intravenous Infusion) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 1, 2017 Category: Drugs & Pharmacology Source Type: news

Nulecit (Sodium Ferric Gluconate Complex Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 1, 2017 Category: Drugs & Pharmacology Source Type: news

Saliva proteins could explain why some people overuse salt
(American Chemical Society) Many Americans consume too much salt. Now in a study appearing in the Journal of Agricultural and Food Chemistry, scientists report that people who can easily taste salt have differing amounts of certain proteins in their saliva than those who are less sensitive. The finding could help explain why some of us have a hard time shaking the salt habit and could potentially lead to the development of more desirable low-sodium foods. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 1, 2017 Category: Biology Source Type: news

Want to Avoid Salt? Turn Up the Spice
Source: HealthDay Related MedlinePlus Pages: High Blood Pressure, Sodium (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 31, 2017 Category: Consumer Health News Source Type: news

Be Wary of Excessive Salt in Some Restaurant Meals
Some restaurant meals can have twice the recommended daily sodium. Take proper steps to avoid overdoing the salt when eating out. (Source: WebMD Health)
Source: WebMD Health - October 30, 2017 Category: Consumer Health News Source Type: news

Exercise-induced anaphylaxis in an elderly patient - Namiki H.
A 75-year-old Japanese woman presented with acute flushing pruritus and a feeling of diffuse warmth followed by collapse while dancing. After resting for 30  min and receiving a rapid infusion of 0.9% sodium chloride, her condition stabilised. She admitte... (Source: SafetyLit)
Source: SafetyLit - October 30, 2017 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

What Causes Hypernatremia?
Discussion Hypernatremia is a serum sodium of> 150 mEq/L. Basic causes are too much sodium or too little free water. If body weight is normal or increased, there is an increase in total body sodium without an appropriate increase in total body water. Normally when the serum sodium is increased there is transient hypertonicity of the plasma which causes the thirst center to be stimulated and antidiuretic hormone (ADH) to be released. The thirst center tells the person to drink more water and ADH causes the kidney to retain free water. This normally will allow the plasma tonicity to go back to normal. Treatment is by tr...
Source: PediatricEducation.org - October 30, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

In Vitro Efficacy of Essential Oil Mouthrinse versus Dentifrices
ConclusionsWithin typical exposure times, the EO-containing mouthrinse can penetrate deep into the accumulating plaque biofilm compared to the chemotherapeutic dentifrice slurries, and may provide an efficacious alternative to triclosan, when used as an adjunct with a mechanical oral care regimen.Clinical SignificanceUsing viability mapping and CLSM, this study demonstrated that EO-containing mouthrinse penetrates and kills microorganisms deeper and more effectively in plaque biofilm in typical exposure times when compared to dentifrice chemotherapeutic agents, providing an efficacious alternative to triclosan or stannous ...
Source: Dental Technology Blog - October 26, 2017 Category: Dentistry Source Type: news

Pharmaceutical use during pregnancy resulting in premature births, birth defects, and massive costs to insurers
(Natural News) The European Medicines Agency will go over the evidence concerning the harmful effects of an epilepsy pill on unborn babies and decide if the warnings are sufficient enough. The drug, sodium valproate, has been connected to nearly 20,000 babies born with disabilities ever since its introduction in the 1970s, reported the DailyMail.co.uk. Also... (Source: NaturalNews.com)
Source: NaturalNews.com - October 26, 2017 Category: Consumer Health News Source Type: news

Some people with cystic fibrosis might live longer because of genetic mutations
(Boston Children's Hospital) Research suggests that genetic mutations to an 'epithelial sodium pathway' could protect against cystic fibrosis and its debilitating effects on the lungs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 25, 2017 Category: International Medicine & Public Health Source Type: news

Sodium Bicarbonate Injection, USP (Updated - Currently in Shortage
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 24, 2017 Category: Drugs & Pharmacology Source Type: news

Sodium Chloride 23.4% Injection (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 24, 2017 Category: Drugs & Pharmacology Source Type: news

Sodium Acetate Injection, USP (Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 23, 2017 Category: Drugs & Pharmacology Source Type: news

Fennec banks positive results on heels of move to Nasdaq
On the heels of making its Nasdaq debut – moving from an over-the-counter market it started trading on several years ago – Research Triangle Park-based Fennec Pharmaceuticals (Nasdaq: FENC) has banked positive Phase 3 results for its product for the prevention of hearing loss in pediatric cancer patients receiving chemotherapy. The P hase 3 results – for Fennec’s sodium thiosulfate therapy called PEDMARK – were presented at the International Society of Pediatric Oncology (SIOP) 2017 meeting… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - October 19, 2017 Category: Health Management Authors: Jennifer Henderson Source Type: news

Fennec banks positive results on heels of move to Nasdaq
On the heels of making its Nasdaq debut – moving from an over-the-counter market it started trading on several years ago – Research Triangle Park-based Fennec Pharmaceuticals (Nasdaq: FENC) has banked positive Phase 3 results for its product for the prevention of hearing loss in pediatric cancer patients receiving chemotherapy. The P hase 3 results – for Fennec’s sodium thiosulfate therapy called PEDMARK – were presented at the International Society of Pediatric Oncology (SIOP) 2017 meeting… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 19, 2017 Category: Biotechnology Authors: Jennifer Henderson Source Type: news

Red meat doesn't cause cancer... it's the sodium nitrite added to processed meats
(Natural News) There is a huge misconception in regards to consumption of red meat and processed meats — that too much can increase your risk of getting cancer. But, says Natural News founder/editor Mike Adams, the Health Ranger, that’s not entirely accurate. Actually, it’s the sodium nitrite contained in processed meat that presents the biggest... (Source: NaturalNews.com)
Source: NaturalNews.com - October 18, 2017 Category: Consumer Health News Source Type: news

Ceftriaxone (Ceftriaxone Sodium and Dextrose Injection ) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 18, 2017 Category: Drugs & Pharmacology Source Type: news

Assessment of the Decontamination of Soil Contaminated with Bacillus Anthracis Spores Using Chlorine Dioxide Gas, Methyl Bromide, or Activated Sodium Persulfate
The objective of this study was to provide an understanding of the performance (i.e., efficacy) of these decontamination technologies under a range of environmental conditions. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - October 17, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Med device firms update on impact, recovery from recent natural disasters
A number of medical device companies with facilities in Texas, Florida, Puerto Rico and California updated this week on the revenue impacts and recovery efforts from major hurricanes and wildfires which have slowed production and shut down facilities across the US. Baxter updates on Hurricane Maria recovery Healthcare giant Baxter (NYSE:BAX) said it expects to see a reduction in revenue during its 4th quarter as a result of Hurricane Maria hitting its Puerto Rico operations, but that it hopes to mitigate the impact through “positive performance in other areas of business.” The Deerfield, Ill.-based co...
Source: Mass Device - October 13, 2017 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Baxter Endologix Exactech Inc. Medtronic Source Type: news

Methotrexate Sodium Injection (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 12, 2017 Category: Drugs & Pharmacology Source Type: news

Fosamax Plus D (Alendronate Sodium and Cholecalciferol) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 12, 2017 Category: Drugs & Pharmacology Source Type: news

Hospitals scramble to avert saline shortage in wake of Puerto Rico disaster
The hurricane that wreaked havoc on Puerto Rico last month has driven down production of widely used intravenous solutions, sending several prominent hospitals across the country scrambling to find alternative supplies, change the way they administer drugs and devise backup plans to make the fluids themselves. The products affected are smaller-volume bags of sodium chloride, […]Related:Rats used to spread the black death. Now, poverty plays a role.A mother refused to follow a court order to vaccinate her son. Now she’s going to jail.Doctors thought a woman had cancer — but it was just a reaction to an ol...
Source: Washington Post: To Your Health - October 9, 2017 Category: Consumer Health News Source Type: news

Methylprednisolone Sodium Succinate for Injection, USP (Updated - Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 6, 2017 Category: Drugs & Pharmacology Source Type: news

Sodium Bicarbonate Injection, USP (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 6, 2017 Category: Drugs & Pharmacology Source Type: news

Mylan Launches First AP-rated Generic Avelox(R) Injection
HERTFORDSHIRE, England and PITTSBURGH, Oct. 5, 2017 -- (Healthcare Sales & Marketing Network) -- Mylan N.V. (NASDAQ, TASE: MYL) today announced the U.S. launch of Moxifloxacin Hydrochloride in 0.8% Sodium Chloride Injection, 400 mg/250 mL (1.6 mg/mL) in 2... Biopharmaceuticals, Product Launch Mylan, Moxifloxacin, Avelox, fluoroquinolone, antibacterial (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 5, 2017 Category: Pharmaceuticals Source Type: news

Scorpion-related cardiomyopathy and acute pulmonary edema in a child who is stung by Leiurus abdullahbayrami - Dokur M, Do ğan M, Yagmur EA.
Venom of Leiurus abdullahbayrami (Scorpiones: Buthidae) is an extremely toxic one and it stimulates voltage-gated sodium and potassium channels. In case of a stung by this scorpion; excessive catecholamine release occur and it impairs left ventricle contra... (Source: SafetyLit)
Source: SafetyLit - October 5, 2017 Category: International Medicine & Public Health Tags: Non-Human Animals and Insects Source Type: news

This diet advice could kill you
The American Heart Association says sodium in salt raises blood pressure. They say it increases the risk for heart disease and stroke.  But the latest science says otherwise… A British review of 34 clinical trials showed that cutting down on salt reduced blood pressure only slightly for people with hypertension.1  And a new study in The Lancet found that some low-salt diets could put you at GREATER risk of heart disease and death.2 Researchers analyzed data from 133,118 people. They wanted to see if there was a link between high sodium and heart attack, stroke and death The results were startling. People...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Randall Hall Tags: Health Heart Health Men's Health Nutrition Women's Health Source Type: news

Sodium - Glucose Cotransporter 2 Inhibitors Not Cancer Risk Factor
Overall cancer risk not increased compared with placebo, other active glucose - lowering treatments (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 3, 2017 Category: Cancer & Oncology Tags: Endocrinology, Family Medicine, Geriatrics, Internal Medicine, Nursing, Oncology, Pathology, Pharmacy, Journal, Source Type: news

Gut bacteria metabolism may factor into hypertension
(University of Illinois College of Agricultural, Consumer and Environmental Sciences) One in three American adults suffers from high blood pressure, or hypertension. The disease can be passed down in families, and certain lifestyle factors such as smoking, high-sodium diets, and stress can increase the risk. In recent years, scientists have discovered that certain gut bacteria may contribute to hypertension, as well. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 3, 2017 Category: Biology Source Type: news

Mesothelioma Doctor Creates Preoperative Drink for Patients
Peritoneal mesothelioma specialist Dr. Charles Conway wants to make major surgery an easier, more manageable experience for his patients. His latest innovation — a preoperative, complex-carbohydrate beverage — should help considerably. Conway, director of surgical oncology at the Ridley-Tree Cancer Center in Santa Barbara, California, will begin offering patients the novel drink customized to speed recovery and lessen the risk of dangerous side effects. Conway designed SurgiStrong RecoverAid, a uniquely blended product to fill a void in the growing Enhanced Recovery After Surgery (ERAS) programs that have sprun...
Source: Asbestos and Mesothelioma News - September 29, 2017 Category: Environmental Health Authors: Matt Mauney Tags: citrulline Dr. Charles Conway mesothelioma surgery recovery mesothelioma surgery side effects Ochsner Cancer Center peritoneal mesothelioma preoperative complex-carbohydrate beverage Ridley-Tree Cancer Center Santa Barbara surgery-induce Source Type: news

Scientists discover neurons that make salty chips tasty
A research team at the Beth Israel Deaconess Medical Center in Boston has found a possible explanation for why the average adult eats far more sodium than they should. (Source: the Mail online | Health)
Source: the Mail online | Health - September 27, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Brain circuit that makes you crave salt identified
New research maps the neurons involved in driving sodium appetite in mice. The findings show how salt cravings are controlled by our brains. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 27, 2017 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

Pass the salt: Mapping the neurons that drive salt cravings
(Beth Israel Deaconess Medical Center) A team of scientists in the Division of Endocrinology, Diabetes and Metabolism at Beth Israel Deaconess Medical Center, have shed new light on the process. In research published today in the journal Neuron, a team of scientists working in the lab of Bradford Lowell, M.D., Ph.D., identified the sub-population of neurons that respond to the body's sodium deficiency and mapped the brain circuitry underlying the drive to consume salt. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 27, 2017 Category: International Medicine & Public Health Source Type: news

Epilepsy drug risk hidden for 40 years harming thousands
An estimated 20,000 British children have been severely harmed because their mothers took the drug sodium valproate during pregnancy. (Source: the Mail online | Health)
Source: the Mail online | Health - September 27, 2017 Category: Consumer Health News Source Type: news

We've had no help - epilepsy drug victims
Families say they have been left to fight for care and help for disabled children harmed by sodium valproate. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 26, 2017 Category: Consumer Health News Source Type: news

Experts warn of heart risks for people with diabetes
240,000 Type 2 diabetics have cardiovascular diagnosis annually Related items fromOnMedica Sodium intake linked to diabetes in adults GPs should test all over 40s for diabetes, NICE says Cases of reversed type 2 diabetes must be highlighted 'Disturbing' type 2 diabetes rise in children Annual diabetes checks reduce mortality risk for people with diabetes (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 25, 2017 Category: UK Health Source Type: news

Mothers say they were deceived about epilepsy pills risks
Julie Marjot, from Norfolk, told the BBC doctors waited until her last child was born to reveal the sodium valproate pills harmed three of her four children. The drug was introduced in the 1970s. (Source: the Mail online | Health)
Source: the Mail online | Health - September 22, 2017 Category: Consumer Health News Source Type: news

Epilepsy drug warnings during pregnancy ‘not reaching women’
Warnings about the risk posed by taking the epilepsy drug sodium valproate during pregnancy are note reaching patients, a charity survey has indicated. (Source: Nursing Times)
Source: Nursing Times - September 22, 2017 Category: Nursing Source Type: news

Epilepsy drug warnings 'not reaching women', survey shows
Sodium valproate risks harming unborn babies, but 70% of women say they were not informed of the risk. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 21, 2017 Category: Consumer Health News Source Type: news

Mum's regret after taking epilepsy drug
Three of Julie Marjot's children have been affected by sodium valproate. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 21, 2017 Category: Consumer Health News Source Type: news

Epilepsy drug's safety reviewed over pregnancy risk
Women whose children have been harmed by sodium valproate will give evidence to a European panel. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 21, 2017 Category: Consumer Health News Source Type: news

MiMedx files IND for Ph2 AmnioFix osteoarthritis trial
MiMedx (NSDQ:MDXG) said today that it filed an IND with the FDA for a Phase II trial of its AmnioFix product in patients with osteoarthritis of the knee. The 318-patient study is designed to compare the safety and efficacy of MiMedx’s micronized dehydrated human amnion/chorion membrane (dHACM) injection with a 0.9% sodium chloride USP placebo injection. Get the full story at our sister site, Drug Delivery Business News. The post MiMedx files IND for Ph2 AmnioFix osteoarthritis trial appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - September 19, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Food & Drug Administration (FDA) Orthopedics Wall Street Beat MiMedx Group Inc. Source Type: news