How Does Ebstein ’ s Anomaly Present?
Discussion
Ebstein’s anomaly (EA) accounts for about 0.3-0.5% of all congenital heart disease and about 40% of all tricuspid valve (TV) pathologies. It was first described by Dr. William Ebstein in 1866.
In EA’s simplest form, the TV is displaced inferiorly from the normal hinge points into the right ventricle (RV). This is caused by delamination of both the septal and mural leaflets and they usually form a combined leaflet which can be more adherent to the RV. These anatomical changes causes poor movement of the leaflet(s) and tricuspid regurgitation. Displacement inferiorly can cause decreased RV capacity and...
Source: PediatricEducation.org - March 13, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
What Is Congestive Heart Failure?
WEDNESDAY, Feb. 15, 2023 -- Congestive heart failure is a scary diagnosis nobody wants to hear, but what is the condition and how do you manage it?
Plenty of people are affected: Roughly 5.7 million Americans are living with congestive heart... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 15, 2023 Category: General Medicine Source Type: news
Janssen Data at ASCO GU Support Ambition to Transform Treatment of Prostate and Bladder Cancer Through Precision Medicine and Early Intervention
RARITAN, N.J., February 13, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced plans to present more than 20 abstracts featuring seven oncology therapies from its robust portfolio and pipeline at the annual American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium, taking place in San Francisco on February 16-18. Building on more than a decade of leadership in the development of medicines for people diagnosed with GU cancers, Janssen will present data demonstrating its ambition to advance patient-centered treatment through precision medicine, real-world evidence a...
Source: Johnson and Johnson - February 13, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Heart Failure Risk Lingers Long After Chemotherapy, Regardless of Dose
(MedPage Today) -- Anthracycline users with breast cancer or lymphoma had an upfront risk of congestive heart failure (CHF) that persisted during long-term follow-up in a population-based case-control study.
The cumulative incidence of new-onset... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 3, 2023 Category: Cardiology Source Type: news
STRONG-HF study results demonstrate clear benefits for acute heart failure patients
STRONG-HF study primary outcomes showed significant reduction of all cause death or acute heart failure readmissions, at day 180, when the study strategy was implementedRapid, simultaneous up-titration of therapies, and close follow-up, led to increased patient quality of life.The RocheElecsys® NT-proBNP biomarker is an integral part of the treatment strategy, comprising rapid up-titration and close follow up after an acute heart failure admissionBasel, 9 November 2022 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced publication of the Safety, Tolerability and Efficacy of Rapid Optimization of Heart Failure (STRONG-HF...
Source: Roche Media News - November 9, 2022 Category: Pharmaceuticals Source Type: news
STRONG-HF study results demonstrate clear benefits for acute heart failure patients
STRONG-HF study primary outcomes showed significant reduction of all cause death or acute heart failure readmissions, at day 180, when the study strategy was implementedRapid, simultaneous up-titration of therapies, and close follow-up, led to increased patient quality of life.The RocheElecsys® NT-proBNP biomarker is an integral part of the treatment strategy, comprising rapid up-titration and close follow up after an acute heart failure admissionBasel, 9 November 2022 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced publication of the Safety, Tolerability and Efficacy of Rapid Optimization of Heart Failure (STRONG-HF...
Source: Roche Investor Update - November 9, 2022 Category: Pharmaceuticals Source Type: news
Late-Breaking Data from Pivotal Phase 3 PRECISION Study Demonstrates Significant and Sustained Effect of Aprocitentan on Lowering Blood Pressure for Patients with Difficult-to-Control Hypertension
RARITAN, NJ, November 7, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson, in collaboration with Idorsia Ltd, today announced results from the Phase 3 PRECISION study, which found aprocitentan, an investigational, novel dual endothelin receptor antagonist (ERA), significantly reduced blood pressure (BP) and maintained the effect for up to 48 weeks when added to standardized combination background antihypertensive therapy in patients with difficult-to-control hypertension (sometimes referred to as resistant hypertension). These data were presented as a Late-Breaking Science presentation during the Amer...
Source: Johnson and Johnson - November 7, 2022 Category: Pharmaceuticals Source Type: news
FDA Approves At-Home Furosemide for Heart Failure
(MedPage Today) -- The FDA approved the first furosemide (Furoscix) formulation for subcutaneous self-administration by patients with congestive heart failure, scPharmaceuticals announced.
The IV-equivalent formulation is indicated for the treatment... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - October 10, 2022 Category: Urology & Nephrology Source Type: news
Hospital outcomes for patients with pulmonary arterial hypertension in sepsis and septic shock.
Background: Pulmonary arterial hypertension (PAH) is associated with increased morbidity and mortality risk. The risk for adverse outcomes in patients with PAH in sepsis or septic shock (SSS) is uncertain.
Methods: Adult patients diagnosed with SSS were identified in the National Readmissions Database over the years 2016-2017. A 2:1 ratio nearest propensity matching method was employed for several demographic, social, and clinical variables. In-hospital outcomes were compared between patients with PAH and those without, using t-test and chi-squared test as appropriate. Patients with cardiogenic shock were excluded. Releva...
Source: Current Awareness Service for Health (CASH) - October 7, 2022 Category: Consumer Health News Source Type: news
Mayo Clinic Q & amp;A podcast: Reducing the risk of heart failure
Heart failure — sometimes known as congestive heart failure — occurs when the heart muscle doesn't pump blood as well as it should. When this happens, blood often backs up and fluid can build up in the lungs, causing shortness of breath. "The most recognized, the most common symptom of heart failure is breath lessness," says Dr. Gosia Wamil, a cardiologist at Mayo Clinic Healthcare in London. "And the type of breathlessness that patients would describe most often is… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 7, 2022 Category: Databases & Libraries Source Type: news
Drug Repurposing Study Could Identify New Mesothelioma Treatments
The next breakthrough in the treatment of malignant mesothelioma may be quietly underway.
An international research team based at Temple University in Philadelphia recently identified four drug compounds – already being used safely for noncancerous conditions – that have shown impressive potential for treating mesothelioma. They were part of a novel drug repurposing project aimed at uncovering much-needed options for mesothelioma patients.
“Mesothelioma has shown resistance to all current treatments, including immunotherapy. Novel combinations are badly needed now,” Dr. Antonio Giordano, director of Sbarro He...
Source: Asbestos and Mesothelioma News - July 6, 2022 Category: Environmental Health Authors: Fran Mannino Tags: Clinical Trials/Research/Emerging Treatments Mesothelioma Source Type: news
Outcomes of CMS-mandated fluid administration among fluid-overloaded patients with sepsis: A systematic review and meta-analysis
The outcomes of large-volume IVF administration to septic shock patients with comorbid congestive heart failure (CHF) and/or end-stage renal disease (ESRD) are uncertain and widely debated in the existing literature. Despite this uncertainty, CMS continues to recommend that 30 ml/kg of an intravenous crystalloid solution be administered to patients in septic shock starting within 3 h of presentation. We performed a systematic review and meta-analysis to assess the relationship between adherence to this guideline and outcomes among patients whose underlying comorbidities present a risk of fluid overload. (Source: Current Aw...
Source: Current Awareness Service for Health (CASH) - June 10, 2022 Category: Consumer Health News Source Type: news
How Healthcare Fails the Homeless How Healthcare Fails the Homeless
Many of the things that kill the homeless are the same that sicken and kill others -- liver disease, congestive heart failure, substance abuse. But the system isn ' t equipped to handle the problems.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 30, 2022 Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news
Slash health: 'I was fortunate. I didn’t die' - guitarist on drug-induced heart disease
LEGENDARY guitarist Slash, born Saul Hudson, made his name as part of hard rock band Guns N' Roses. Having reached the height of his fame in the 1990s, Slash struggled with both drugs and alcohol addiction, a habit that would severely damage his long-term health as back in 2001, he was diagnosed with cardiomyopathy, a form of congestive heart failure. (Source: Daily Express - Health)
Source: Daily Express - Health - April 22, 2022 Category: Consumer Health News Source Type: news
Congestive Heart Failure
kls117@duke.eduWed, 04/06/2022 - 16:22
Treatment PageCongestive Heart Failure
ProvidersRicha Agarwal, MDAdam D. DeVore, MD, MHSG. Michael Felker, MD, MHSMarat Fudim, MD, MHSStephen J. Greene, MDAdrian F. Hernandez, MD, MHSChristopher L. Holley, MD, PhDRavi Karra, MD, MHSJason N. Katz, MD, MHSMichel G. Khouri, MDRobert J. Mentz, MDKishan S. Parikh, MDChetan B. Patel, MDPaul B. Rosenberg, MDStuart D. Russell, MDMichael A. Blazing, MDNathan M. Allen, AGPNP-CDennis M. Abraham, MDMargaret "Midge" Bowers, DNP, FNP-BCCarolyn L. Lekavich, PhD, ANP-CKevin D. Cox, FNP-BCStephanie G. Barnes, MSN, AGPCNP-BC, PCCNKhyati Baxi, MDG...
Source: dukehealth.org: Health Tips - April 6, 2022 Category: Primary Care Authors: kls117 at duke.edu Source Type: news
