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The Role of Metformin in PCOS-Related Infertility The Role of Metformin in PCOS-Related Infertility
Peter Kovacs comments on a new guideline from the American Society for Reproductive Medicine on the use of metformin for ovulation induction in women with polycystic ovary syndrome.Medscape Ob/Gyn (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 7, 2017 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Viewpoint Source Type: news

Synjardy XR Extended-release Tablets (Empagliflozin and Metformin Hydrochloride Extended-release) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 30, 2017 Category: Drugs & Pharmacology Source Type: news

Diabetes Medications Have Different Effects on the Liver Diabetes Medications Have Different Effects on the Liver
For people with advanced liver fibrosis and type 2 diabetes, metformin is better than sulfonylureas, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 26, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Obesity, Type 2 Diabetes and Metformin Obesity, Type 2 Diabetes and Metformin
Metformin is commonly used in the management of type 2 diabetes, but could it also provide benefit in the treatment of obesity in children?Archives of Disease in Childhood (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 25, 2017 Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news

Statin use link to heightened type 2 diabetes risk in some people
30% higher risk of diabetes in susceptible individuals Related items fromOnMedica Statins' side effects have been overstated, study suggests Starting statins not beneficial in many older adults Taking statins linked to improved heart structure and function Almost 12 million more people should be on statins Metformin doesn ’t help HbA1c in teens with type 1 diabetes (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 24, 2017 Category: UK Health Source Type: news

Insulin pumps linked to fewer diabetes complications
Pumps also associated with better glycaemic control and lower insulin dosage than injections Related items fromOnMedica Glycosylated haemoglobin (HbA1c) and screening for diabetes Metformin doesn ’t help HbA1c in teens with type 1 diabetes Glucose self-monitoring may not improve control in non-insulin-treated type 2 diabetes Bionic pancreas outperforms insulin pump (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 12, 2017 Category: UK Health Source Type: news

Prediabetes drug increases risk of diabetes!
Raise your hand if your doctor has ordered a blood test to check your glucose. Most do, whether or not you have symptoms of diabetes. If your fasting blood sugar is 125 mgm/dL or above you are considered a diabetic. But if your number comes in between 108 and 125 they’ll say you have “prediabetes.”  That’s a condition where your cells have a resistance to the hormone insulin. Your body uses insulin to put glucose into your cells where it can provide energy. But with insulin resistance, your cells are slow to take up glucose. It builds up in your blood.  Over a lifetime, 70-75% of people ...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Randall Hall Tags: Health Men's Health Women's Health Source Type: news

Melior begins dosing MLR-1023 in Phase IIb trial to treat type 2 diabetes
US-based Melior Pharmaceuticals I has begun dosing in a Phase IIb trial aimed at evaluating the efficacy of MLR-1023, an oral insulin sensitizer, in adult patients with uncontrolled type 2 diabetes on metformin therapy. (Source: Drug Development Technology)
Source: Drug Development Technology - October 4, 2017 Category: Pharmaceuticals Source Type: news

Comparison of Myo-Inositol and Metformin in PCOS Comparison of Myo-Inositol and Metformin in PCOS
A new study compares the effects of treatment with myo-inositol or metformin among women with PCOS.Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 3, 2017 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news

Diabetes drug cuts Parkinson's risk by 28%
Researchers from the University of Bergen in Norway found glitazones (GTZs) have a protective effect. The figure is in comparison with users of metformin, the most common type 2 drug. (Source: the Mail online | Health)
Source: the Mail online | Health - October 2, 2017 Category: Consumer Health News Source Type: news

Pioglitazone, Sulfonylureas Safe and Effective in Type 2 Diabetes Pioglitazone, Sulfonylureas Safe and Effective in Type 2 Diabetes
They may not boast a cardiovascular benefit like other newer drugs, but these drugs can safely be added to metformin to manage type 2 diabetes.Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 29, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Commentary Source Type: news

Ertugliflozin: Promise From Yet Another SGLT-2 Inhibitor (CME/CE)
(MedPage Today) -- Assessed as triple agent therapy when added to metformin, sitagliptin (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 25, 2017 Category: Cardiology Source Type: news

Another SGLT2 Inhibitor, Ertugliflozin, Meets Goals in Two Trials Another SGLT2 Inhibitor, Ertugliflozin, Meets Goals in Two Trials
In two phase 3 trials, the SGLT2 inhibitor ertugliflozin for the treatment of type 2 diabetes that is uncontrolled with metformin alone or with sitagliptin demonstrated safety and efficacy at 52 weeks.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 25, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

REMOVAL Update: More Benefits of Metformin in T1D REMOVAL Update: More Benefits of Metformin in T1D
New REMOVAL data presented at EASD 2017 reveal effects of metformin on renal function, biomarkers, and more in patients with type 1 diabetes.Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 22, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Commentary Source Type: news

Sulfonylureas, Pioglitazone Similarly Safe for Add-On Therapy in Type 2 Diabetes (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD For patients with type 2 diabetes inadequately controlled with metformin, add-on treatment with either a sulfonylurea or pioglitazone seems similarly safe over the long-term, according to an open-label, multicenter study in … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 14, 2017 Category: Primary Care Source Type: news

For Metformin Add-On, No Winner in Head-to-Head CVD Trial (CME/CE)
(MedPage Today) -- Pioglitazone largely similar to sulfonylurea in pragmatic TOSCA.IT trial (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - September 13, 2017 Category: Urology & Nephrology Source Type: news

Deals this week: Mundipharma Medical Company, Cooper Pharmal Sarl, Merck
Mundipharma Medical Company will exclusively distribute INVOKANA (canagliflozin) and VOKANAMET (canagliflozin and metformin) in the European Economic Area (EEA) and Switzerland, under an agreement signed with drug developer and manufacturer Janssen P … (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - September 7, 2017 Category: Pharmaceuticals Source Type: news

Janssen and Mundipharma sign distribution deal for type 2 diabetes treatments
Janssen Pharmaceutica has entered an exclusive distribution agreement with Mundipharma Medical Company for Invokana (canagliflozin) and Vokanamet (a fixed-dose combination therapy of canagliflozin and metformin) to treat patients with type 2 diabetes … (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - September 4, 2017 Category: Pharmaceuticals Source Type: news

Janumet (Sitagliptin Metformin HCL) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 28, 2017 Category: Drugs & Pharmacology Source Type: news

Metformin Still Cost-effective for Diabetes Prevention Metformin Still Cost-effective for Diabetes Prevention
Metformin plus vitamin B12 supplementation remains cost-effective for preventing progression to diabetes compared with placebo and lifestyle changes, researchers report.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 26, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

$820 million wasted in failing to attempt Type 2 diabetes prevention efforts
(University of South Florida (USF Health)) Lifestyle intervention is the best approach in preventing Type 2 diabetes. However, most patients don't follow through in having a balanced diet and exercise. Prescribing metformin can save $820 million annually in healthcare costs and reduce the number of Type 2 diabetes patients by 20%. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 4, 2017 Category: International Medicine & Public Health Source Type: news

FDA Drug Safety Communication: FDA requires removal of some prescribing and dispensing restrictions for rosiglitazone-containing diabetes medicines
The U.S. Food and Drug Administration (FDA) has determined that recent data for rosiglitazone-containing drugs, such as Avandia, Avandamet, Avandaryl, and generics, do not show an increased risk of heart attack compared to the standard type 2 diabetes medicines metformin and sulfonylurea. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 1, 2017 Category: Drugs & Pharmacology Source Type: news

A therapy for FXS?
The antidiabetic drug metformin might be repurposed to treat patients with fragile X syndrome. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 4, 2017 Category: Science Authors: Ferrarelli, L. K. Tags: STKE Editors ' Choice Source Type: news

Metformin Particularly Effective in Those With History of GDM Metformin Particularly Effective in Those With History of GDM
Women who have had diabetes during pregnancy appear to profit the most from metformin treatment to reduce the risk of developing type 2 diabetes, according to the latest findings from the DPP study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 29, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Antioxidant in Broccoli May Help Fight Diabetes Antioxidant in Broccoli May Help Fight Diabetes
A study finds broccoli extract containing the antioxidant sulforaphane decreased HbA1c and fasting blood sugar in obese patients with type 2 diabetes taking metformin but who had uncontrolled glycemia.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 22, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Broccoli sprout extract can replace toxic metformin drugs in type-2 diabetes; sulforaphane found to control blood sugar levels
(Natural News) The American Diabetes Association reports that around 10 percent of the U.S. population has diabetes, most of whom have lifestyle-related type 2 diabetes. Around 1.4 million new diabetes diagnoses are made each year, and it remains the seventh leading cause of death in the U.S. This is also an incredibly expensive disease, costing... (Source: NaturalNews.com)
Source: NaturalNews.com - June 22, 2017 Category: Consumer Health News Source Type: news

Specific diabetes medications recommended to protect bone health
Research highlights treatment options for co-managing type 2 diabetes and osteoporosis Related items fromOnMedica Osteoporosis - treatment options Osteoporosis - primary prevention Metformin lowers cardiac deaths better than other drugs Drug could cut heart events by 26% in diabetics (Source: OnMedica Latest News)
Source: OnMedica Latest News - June 22, 2017 Category: UK Health Source Type: news

Metformin No Help for Atherosclerosis in T1D
(MedPage Today) -- Findings don't support metformin in long-standing type 1 diabetes (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - June 13, 2017 Category: Cardiology Source Type: news

Metformin for Obesity in Children: Questions Still Remain Metformin for Obesity in Children: Questions Still Remain
Metformin improved body mass index in nondiabetic obese prepubertal -- but not pubertal -- children, a new study has found.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 13, 2017 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Novel SGLT-2 Inhibitor Boosts Glycemic Control
(MedPage Today) -- A1c reduced when paired with metformin monotherapy (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - June 12, 2017 Category: Cardiology Source Type: news

ADA 2017: Oral Agents Under Review
When to start screening for B12 deficiency in your diabetes patients taking metformin? We review a dose-response diet study plus 2 others on oral drugs. (Source: ConsultantLive)
Source: ConsultantLive - June 12, 2017 Category: Internal Medicine Authors: Kenneth J. Bender, PharmD Tags: Conferences/ADA 2017 Diabetes Diabetes Type 2 Source Type: news

REMOVAL: Mixed Data on CV Benefits of Metformin in Type 1 Diabetes REMOVAL: Mixed Data on CV Benefits of Metformin in Type 1 Diabetes
Results from REMOVAL trial suggest possible cardiovascular benefit, but minimal effect on glucose lowering, in type 1 diabetes patients at increased cardiovascular risk.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 12, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Lifestyle Intervention Benefits Latinas With Prediabetes
(MedPage Today) -- Trend toward HbA1c improvement compared with metformin (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - June 11, 2017 Category: Cardiology Source Type: news

Metformin vs Myoinositol in Obese PCOS Patients Metformin vs Myoinositol in Obese PCOS Patients
Which is the more effective treatment choice for obese patients with PCOS?Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 2, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Jentadueto (Linagliptin and Metformin Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 31, 2017 Category: Drugs & Pharmacology Source Type: news

Long-term Metformin May Reduce Coronary Calcium Long-term Metformin May Reduce Coronary Calcium
At least in men with prediabetes, and independent of statins, suggests a cohort study that did not find a similar effect of metformin on coronary calcium scores in women.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 30, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

UK NICE Elevates SGLT2 Inhibitors in Diabetes Guidance UK NICE Elevates SGLT2 Inhibitors in Diabetes Guidance
The sodium-glucose cotransporter 2 (SGLT2) inhibitor class is now listed clearly as a second-line option after metformin in type 2 diabetes.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 26, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Common diabetes drug may work by changing gut bacteria
A group of diabetics taking metformin had drastic changes in their gut flora, found Swedish and Spanish researchers.A probiotic diet may be beneficial for people with diabetes, say scientists. (Source: the Mail online | Health)
Source: the Mail online | Health - May 23, 2017 Category: Consumer Health News Source Type: news

No Link to Cognition in Diabetes Prevention Program Study
Intensive lifestyle intervention, metformin not tied to cognition (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - May 22, 2017 Category: Psychiatry Tags: Endocrinology, Family Medicine, Geriatrics, Internal Medicine, Neurology, Nursing, Pharmacy, Psychiatry, Journal, Source Type: news

Long-term Metformin Use'Has No Cognitive Impact'Long-term Metformin Use'Has No Cognitive Impact '
Patients and clinicians can be reassured that long-term use of metformin does not lead to worsening cognitive performance, new results from prolonged follow-up of the large-scale diabetes-prevention program indicate.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 19, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Metformin Improves Outcomes in HER2+ Breast Cancer Patients With Diabetes
Treatment with metformin may improve outcomes in patients with HER2 –positive primary breast cancer and diabetes, according to an analysis of the phase III ALTTO trial. (Source: CancerNetwork)
Source: CancerNetwork - May 16, 2017 Category: Cancer & Oncology Authors: Dave Levitan Tags: Breast Cancer HER2-Positive Breast Cancer News Source Type: news

Diabetes drug may help symptoms of autism-associated condition
Metformin, the most widely used drug to treat type 2 diabetes, could potentially be used to treat symptoms of Fragile X syndrome, an inherited form of intellectual disability and a cause of some forms of autism. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 15, 2017 Category: Science Source Type: news

Medical News Today: Metformin shows promise as a potential treatment for fragile X syndrome
New study shows that treatment with the common type 2 diabetes drug metformin improves social, behavioral, and neuron deficits in mouse model of fragile X. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 15, 2017 Category: Consumer Health News Tags: Autism Source Type: news

Diabetes drug may help symptoms of autism-associated condition
Metformin, the most widely used drug to treat type 2 diabetes, could potentially be used to treat symptoms of Fragile X syndrome, an inherited form of intellectual disability and a cause of some forms of autism. A new study led by researchers at McGill University, the University of Edinburgh and Université de Montréal has found that metformin improves social, behavioural and morphological defects in Fragile X mice. (Source: World Pharma News)
Source: World Pharma News - May 15, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Diabetes drug may help symptoms of autism associated condition
(University of Edinburgh) A widely used diabetes medication could help people with a common inherited form of autism, research shows. Scientists found that a drug called metformin improves sociability and reduces symptomatic behaviors in adult mice with a form of Fragile X syndrome. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 15, 2017 Category: International Medicine & Public Health Source Type: news

Medical News Today: Is it safe to use metformin during pregnancy?
Metformin is commonly prescribed for managing type 2 diabetes. Although it effectively lowers blood sugar, is it safe for women to take during pregnancy? (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 12, 2017 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news

More Side Effects With CRT Plus Metformin in Head, Neck Cancer
Metformin group less likely to tolerate cisplatin, have grade ≥ 3 nausea/vomiting, hematologic toxicities (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - May 5, 2017 Category: Cancer & Oncology Tags: Endocrinology, Internal Medicine, Oncology, ENT, Pharmacy, Journal, Source Type: news

Medical News Today: Can you drink alcohol while taking metformin?
People with diabetes may use metformin to help manage their symptoms. In this article, we look at the risks of consuming alcohol while on this medication. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 5, 2017 Category: Consumer Health News Tags: Diabetes Source Type: news

More Support for Metformin Benefit in Breast Cancer (CME/CE)
(MedPage Today) -- Better outcomes but only in hormone receptor-positive disease (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 4, 2017 Category: Cardiology Source Type: news

Metformin Use Does Not Increase Prostate Cancer Survival
Drug given in combination with docetaxel chemotherapy in patients with metastatic disease (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - April 11, 2017 Category: Cancer & Oncology Tags: Endocrinology, Oncology, Pharmacy, Urology, Journal, Source Type: news