Understanding the impact of patient empowerment and remote management in rheumatoid arthritis
(European Alliance of Associations for Rheumatology) Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It can also cause fatigue, and the underlying inflammation may affect other body systems. In people with RA, low empowerment is associated with worse health. Interventions to improve empowerment may include helping people to master their pain, increase physical function, and improve physical activity. Remote technologies to support patient-reported self-assessment may help improve patient empowerment and disease management. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 14, 2021 Category: International Medicine & Public Health Source Type: news

Janssen Announces Results from Phase 3 MAIA Study Showing Significant Overall Survival Benefits for Treatment with DARZALEX ® (daratumumab) in Patients with Newly Diagnosed Multiple Myeloma Who are Transplant Ineligible
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced overall survival (OS) results from the Phase 3 MAIA (NCT02252172) study showing the addition of DARZALEX® (daratumumab) to lenalidomide and dexamethasone (D-Rd) resulted in a statistically significant survival benefit over lenalidomide and dexamethasone (Rd) alone in patients with newly diagnosed multiple myeloma (NDMM) who were ineligible for autologous stem cell transplant (ASCT) and were treated to progression.[1] These data were featured in the European Hematology Association (EHA) 2021 Virtual Press Briefin...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Language Barriers May Contribute to Pain Management Disparities Language Barriers May Contribute to Pain Management Disparities
Patients whose first language is not English received fewer pain assessments and fewer doses of NSAIDs and oxycodone therapeutic equivalents following cesarean deliveries, new research suggestsMedscape Medical News (Source: Medscape Med Students Headlines)
Source: Medscape Med Students Headlines - June 10, 2021 Category: Universities & Medical Training Tags: Ob/Gyn & Women ' s Health News Source Type: news

Barriers to Cancer Pain Management During the Opioid Crisis Barriers to Cancer Pain Management During the Opioid Crisis
Have increasing patient concerns about the potential harmful effects of opioid medications impacted their access to adequate cancer pain management?Pain (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 7, 2021 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Roswell Park Team Demonstrates Safe Approach for Dramatically Reducing...
A pain-management protocol designed by Roswell Park gynecologic oncologist Emese Zsiros, MD, PhD, FACOG, to be reported at the American Society of Clinical Oncology 2021 annual meeting, resulted in a...(PRWeb June 05, 2021)Read the full story at https://www.prweb.com/releases/roswell_park_team_demonstrates_safe_approach_for_dramatically_reducing_use_of_opioids_following_surgery/prweb17987514.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - June 5, 2021 Category: Pharmaceuticals Source Type: news

The week in bankruptcies: The Academy of Integrative Pain Management
Sacramento area bankruptcy courts recorded one business filing — including zero with total debt above $1 million — during the week that ended May 28. Year to date through May 28, the court recorded 18 Chapter 7 or Chapter 11 business bankruptcy filings, a 22% decrease from the same span the prior year. Chapter 7 bankruptcy protection typically provides for the liquidation of a business’ assets to satisfy creditor claims, while Chapter 11 protection enables a business to restructure its creditor… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - June 4, 2021 Category: Health Management Source Type: news

Cells to Society: Adaptation and Advancement
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Source: Johns Hopkins University and Health Systems Archive - June 4, 2021 Category: Nursing Source Type: news

New Phase 3b Psoriatic Arthritis (PsA) Data Show First-in-Class TREMFYA ® (guselkumab) Achieved Robust Joint Symptom Improvement and Complete Skin Clearance in Patients with Inadequate Response to Tumor Necrosis Factor Inhibition (TNFi-IR)
SPRING HOUSE, PENNSYLVANIA, June 2, 2021 – Today the Janssen Pharmaceutical Companies of Johnson & Johnson announced new efficacy and safety data for first-in-class TREMFYA® (guselkumab), including data from the first study evaluating a selective IL-23 inhibitor in adult patients with active PsA, all of whom had demonstrated inadequate response or intolerance to TNFi.1 In the COSMOS Phase 3b study, significantly higher proportions of patients treated with TREMFYA showed joint symptom improvement and complete skin clearance versus placebo at week 24 in this true TNFi-IRa patient population, which is often more...
Source: Johnson and Johnson - June 2, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Highlights Commitment to Advancing Transformative Innovations in Oncology with Scientific Updates from Deep, Diverse Pipeline and Portfolio at ASCO and EHA Virtual Scientific Programs
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 30 company-sponsored studies, including six oral presentations, will be featured during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, June 4-8. Janssen presentations will include new data and updates for both approved and investigational therapeutics that are being studied for the treatment of various solid tumors and blood cancers. Immediately following ASCO, additional data will be featured during the European Hematology Association (EHA) Virtual Congress, June 9-17. A ...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Reports New Data for BCMA CAR-T, Cilta-Cel, Showing Deep and Durable Responses in Patients with Relapsed or Refractory Multiple Myeloma
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data for ciltacabtagene autoleucel (cilta-cel), an investigational B-cell maturation antigen (BCMA)-directed CAR-T therapy, demonstrated sustained efficacy and durable responses in heavily pretreated patients with relapsed/refractory multiple myeloma (RRMM). Updated results from the Phase 1b/2 CARTITUDE-1 study (n=97) with a longer-term follow-up at a median of 18 months showed an overall response rate (ORR) of 98 percent, with 80 percent of patients achieving a stringent complete response (sCR), highlight...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Updated Data Demonstrate Significant Improvement in Hematologic Complete Response with DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) in Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
RARITAN, N.J., May 26, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced updated results from the Phase 3 ANDROMEDA study, which evaluated DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) for the treatment of patients with newly diagnosed light chain (AL) amyloidosis, a rare blood cell disorder associated with the deterioration of vital organs, most notably the heart, kidneys and liver.[1] Longer-term results from a median follow-up of 20.3 months showed rates of hematologic complete response (hemCR) remained significantly higher in patients treated with DARZALEX FASPRO®...
Source: Johnson and Johnson - May 26, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Long-Term ERLEADA ® (apalutamide) Patient-Reported Outcomes Data in Metastatic Castration-Sensitive Prostate Cancer Demonstrate Maintenance of Health-Related Quality of Life for Patients
May 26, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced patient-reported outcomes (PRO) data from the pre-specified final analysis of the Phase 3 TITAN study in patients with metastatic castration-sensitive prostate cancer (mCSPC). The TITAN study previously demonstrated statistically significant improvement in overall survival (OS) after a median follow-up of 44 months in patients receiving ERLEADA® plus androgen deprivation therapy (ADT).1 The new PRO data showed that the addition of ERLEADA® to ADT maintained patients’ health-related quality of lif...
Source: Johnson and Johnson - May 26, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Lumbar spine x-ray may not be needed for lower back pain
Women whose lumbar spine x-rays showed degeneration over time experienced littl...Read more on AuntMinnie.comRelated Reading: Hospital-based doctors order more inappropriate MRI scans CT, MRI for lower back pain still prevalent in ED SNMMI: FDG-PET/MRI improves pain diagnosis, management Are too many patients getting MRI scans for back pain? CT-guided pulsed radiofrequency provides back pain relief (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - May 21, 2021 Category: Radiology Source Type: news

Addiction and Pain Management
If you’ve battled a drug or alcohol addiction, you may be nervous about taking medications that treat pain, such as opioids. Learn more about the options you might have and how to weigh them. (Source: WebMD Health)
Source: WebMD Health - May 17, 2021 Category: Consumer Health News Source Type: news

Review article: paramedic pain management of femur fractures in the prehospital setting: a systematic review - Davis S, Olaussen A, Bowles KA, Shannon B.
Femur shaft and neck of femur (NOF) fractures are often undertreated in the prehospital setting. These injuries can present unique clinical and logistical concerns in the prehospital setting. This systematic review aimed to investigate paramedic prehospita... (Source: SafetyLit)
Source: SafetyLit - May 17, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

What are Common Causes of Anaphylaxis?
Discussion Anaphylaxis is a potentially life-threatening hypersensitivity reaction of the body. Usually anaphylaxis is IgE mediated but complement-mediated immune complex reactions or IgG mediated reactions can cause anaphylaxis. Usually mucous membranes or skin are involved, but it is a systemic disease process with at least 2 systems involved (respiratory is second most common followed by gastrointestinal system). The epidemiology is difficult to discern but the estimated incidence is about 50-112 episodes per 100,000 person-years and estimated prevalence is 0.3-5.1%. There is data supporting an increased incidence. Over...
Source: PediatricEducation.org - May 17, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Heron Therapeutics Announces U.S. FDA Approval of ZYNRELEF(TM) (HTX-011) for the Management of Postoperative Pain for up to 72 Hours
ZYNRELEF is the first and only FDA-approved extended-release dual-acting local anesthetic, clinically proven to manage pain and to eliminate the need for opioids for up to 72 hours following surgery better than bupivacaine solution, the current standard-of... Biopharmaceuticals, FDA Heron Therapeutics, ZYNRELEF, bupivacaine, meloxicam (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 13, 2021 Category: Pharmaceuticals Source Type: news

FDA Approves Zynrelef (bupivacaine and meloxicam) for the Management of Postoperative Pain
SAN DIEGO, May 13, 2021 /PRNewswire/ -- Heron Therapeutics, Inc. (Nasdaq: HRTX), a commercial-stage biotechnology company focused on improving the lives of patients by developing best-in-class treatments to address some of the most important unmet... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - May 13, 2021 Category: Drugs & Pharmacology Source Type: news

HSS researchers find duloxetine may reduce opioid use after total knee replacement
(Hospital for Special Surgery) In a study conducted by researchers at HSS, cumulative opioid use was reduced by 30% in a patient group that received duloxetine after total knee arthroplasty (TKA) compared with patients who received placebo. Patients who received duloxetine also reported higher pain management satisfaction and less pain interference with mood, walking, normal sleep, and work activities. These findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 13, 2021 Category: International Medicine & Public Health Source Type: news

Centre issues advisory on management of Mucormycosis fungal infection in COVID-19 patients
Warning symptoms include pain and redness around eyes and nose, fever, headache, coughing, shortness of breath, bloody vomits and altered mental status, the advisory stated. (Source: The Economic Times)
Source: The Economic Times - May 9, 2021 Category: Consumer Health News Source Type: news

An integrative review of arts-based strategies for addressing pain and substance use disorder during the opioid crisis - Leis JA, Morrison CI.
In October 2017, the U.S. Department of Health& Human Services declared the opioid crisis a national public health emergency and prioritized identifying effective, evidence-based strategies for pain management and the prevention and treatment of substance... (Source: SafetyLit)
Source: SafetyLit - May 6, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Non-invasive management of soft tissue disorders of the shoulder: a clinical practice guideline from the Ontario Protocol for Traffic Injury Management (OPTIMa) collaboration - Yu H, C ôté P, Wong JJ, Shearer HM, Mior S, Cancelliere C, Randhawa K, Ameis A, Carroll LJ, Nordin M, Varatharajan S, Sutton D, Southerst D, Jacobs C, Stupar M, Taylor-Vaisey A, Gross DP, Brison RJ, Paulden M, Ammendolia C, Cassidy JD, Marshall S, Bohay RN, Stapleton J, Lacerte M.
OBJECTIVES: To develop an evidence-based guideline for the non-invasive management of soft tissue disorders of the shoulder (shoulder pain), excluding major pathology. METHODS: This guideline is based on high-quality evidence from seven systematic ... (Source: SafetyLit)
Source: SafetyLit - May 6, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Breaking down barriers to care for metastatic breast cancer patients
Drawing on a series of studies and interviews with patients and caregivers, UCLA researchers from theUCLA Center for Health Policy Research and the UCLA Jonsson Comprehensive Cancer Center have published recommendations for California policymakers and patient advocates aimed at improving care and outcomes for women with metastatic breast cancer.More than 30,000women in California are diagnosed each year with this cancer, which has spread from the breast to other parts of the body. Survival rates are low, and patients often face significant hurdles to care — particularly in the areas of health insurance, cli...
Source: UCLA Newsroom: Health Sciences - April 28, 2021 Category: Universities & Medical Training Source Type: news

Primary Care Management of Suspected Thromboembolism with Thrombocytopenia after COVID-19 Vaccination, RCGP
Serious thromboembolic events with concurrent thrombocytopenia have occurred very rarely following vaccination with AstraZeneca (AZ) COVID-19 vaccine. This includes venous thrombosis, sometimes involving unusual sites such as cerebral venous sinus thrombosis (CVST), splanchnic vein thrombosis, or arterial thrombosis, combined with thrombocytopenia. It is currently estimated that the overall incidence of CVST following the AZ vaccine is around 4 per million first doses administered. Suspected cases have been reported in patients of all ages and genders and currently, no specific predisposing factors have been identified. ...
Source: Current Awareness Service for Health (CASH) - April 26, 2021 Category: Consumer Health News Source Type: news

Johnson & Johnson Single-Shot COVID-19 Vaccinations to Resume in the U.S. for All Adults Aged 18 and Older Following CDC and FDA Decision
NEW BRUNSWICK, N.J., April 23, 2021 – Johnson & Johnson (NYSE: JNJ) (the Company) today announced that vaccinations with the Company’s COVID-19 single-shot vaccine will resume for all adults aged 18 years and older in the U.S., under Emergency Use Authorization (EUA), following a decision from the United States Centers for Disease Control (CDC) and Food and Drug Administration (FDA).The decision was based on a recommendation from the U.S. CDC Advisory Committee on Immunization Practices (ACIP), which followed a rigorous evaluation of data relating to a very rare adverse event involving blood clots in combin...
Source: Johnson and Johnson - April 23, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Association between marijuana use and nonmedical prescription opioid use in the United States: are we shifting from one epidemic to another? - Arora P, Johnson A, Jayasekare R, Desai K.
This study aims to examine the association of mar... (Source: SafetyLit)
Source: SafetyLit - April 23, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

How philosophy can change the understanding of pain
(Ruhr-University Bochum) Dr. Sabrina Coninx from Ruhr-Universit ä t Bochum and Dr. Peter Stilwell from McGill University, Canada, have investigated how philosophical approaches can be used to think in new ways about pain and its management. The researchers advocate not merely reducing chronic pain management to searching and treating underlying physical changes but instead adopting an approach that focuses on the person as a whole. Their work was published online in the journal " Synthese " on 15 April 2021. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 23, 2021 Category: International Medicine & Public Health Source Type: news

Johnson & Johnson Single-Shot COVID-19 Vaccine Phase 3 Data Published in New England Journal of Medicine
NEW BRUNSWICK, N.J., April 21, 2021 – Johnson & Johnson (the Company) today announced publication in the New England Journal of Medicine of primary data from the Phase 3 ENSEMBLE clinical trial for its single-dose COVID-19 vaccine, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen). The publication of the primary analysis follows the topline efficacy and safety data announced in January, showing the trial met all primary and key secondary endpoints, and found that the Johnson & Johnson single-dose COVID-19 vaccine prevented hospitalization and death across all study participa...
Source: Johnson and Johnson - April 21, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Efforts to reduce opioid prescriptions may be hindering end-of-life pain management
(Oregon State University) Policies designed to prevent the misuse of opioids may have the unintended side effect of limiting access to the pain-relieving drugs by terminally ill patients nearing the end of their life, new research led by the Oregon State University College of Pharmacy suggests. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 20, 2021 Category: Cancer & Oncology Source Type: news

Janssen Provides Update on Phase 3 ACIS Study in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with ERLEADA ® (apalutamide) and ZYTIGA® (abiraterone acetate) Plus Prednisone Combination
RARITAN, N.J., April 19, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that regulatory submissions based on the Phase 3 ACIS study, which evaluated the combination of ERLEADA® (apalutamide) and ZYTIGA® (abiraterone acetate) plus prednisone in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC), will not be pursued. As presented at the American Society of Clinical Oncology’s Genitourinary (ASCO GU) Cancers Symposium in February 2021, the ACIS study met its primary endpoint of radiographic progression-free survival (rPFS); ho...
Source: Johnson and Johnson - April 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

A Growing New Health Crisis Focusing on Emergency Rooms, Medical History & Vaccines
Samah Ghalloussi, one of the entrepreneurs interviewed for the article with a worker of the French Red Cross. Credit: French Red CrossBy Angel MendozaPARIS, Apr 19 2021 (IPS) This year’s World Health Day on 7 April was an opportunity for three entrepreneurs to share their insights and reflections on a rather complex year due to the health crisis and comment on their experiences developing impactful products and services in this sector. Emeric Lemaire, co-founder of Arkhn, Samah Ghallousi, CEO of AALIA.tech and Antoine Noel, co-founder and director of Japet, are all either associates of Liberté Living-Lab, (a ...
Source: IPS Inter Press Service - Health - April 19, 2021 Category: International Medicine & Public Health Authors: Angel Mendoza Tags: Featured Global Headlines Health IPS UN: Inside the Glasshouse Population Regional Categories TerraViva United Nations Source Type: news

How Are Iliac Fractures Treated?
Discussion Avulsion fractures of the pelvis are more commonly seen in adults and teenage athletes. Currently they are more common in male athletes but with the increased number of females in sports, more are also being seen in females. Soccer and track and field are common sports where these injuries occur. The injuries are felt to be caused by a repetitive traction on the apophysis or more commonly due to a ‘sudden, forceful, or unbalanced contraction of an attached musculotendinous unit while engaged in a sporting event…. Skeletal maturity has a direct effect on the incidence of the injury.” They can o...
Source: PediatricEducation.org - April 19, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Johnson & Johnson Statement on CDC Advisory Committee Meeting on Company COVID-19 Vaccine
NEW BRUNSWICK, N.J., April 14, 2021 – The U.S. Centers for Disease Control and Prevention (CDC) Advisory Committee on Immunization Practices (ACIP) convened today to consider reports of an extremely rare disorder involving blood clots in combination with low platelets observed in a small number of individuals following vaccination with the Johnson & Johnson COVID-19 vaccine. “The safety and well-being of the people who use our products is our number one priority, and we strongly support awareness of the signs and symptoms of this extremely rare event to ensure the correct diagnosis, appropriate treatment an...
Source: Johnson and Johnson - April 15, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Trinity Natural Health & Pain Management, Inc. - 614007 - 04/13/2021
Unapproved and Misbranded Products Related to Coronavirus Disease 2019 (COVID-19) (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - April 14, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Johnson & Johnson Statement on COVID-19 Vaccine
NEW BRUNSWICK, N.J., April 13, 2021– The safety and well-being of the people who use our products is our number one priority. We are aware of an extremely rare disorder involving people with blood clots in combination with low platelets in a small number of individuals who have received our COVID-19 vaccine. The United States Centers for Disease Control (CDC) and Food and Drug Administration (FDA) are reviewing data involving six reported U.S. cases out of more than 6.8 million doses administered. Out of an abundance of caution, the CDC and FDA have recommended a pause in the use of our vaccine. In addition, we have ...
Source: Johnson and Johnson - April 13, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Johnson & Johnson Statement on COVID-19 Vaccine (Updated)
NEW BRUNSWICK, N.J., April 13, 2021– The safety and well-being of the people who use our products is our number one priority. We are aware of an extremely rare disorder involving people with blood clots in combination with low platelets in a small number of individuals who have received our COVID-19 vaccine. The United States Centers for Disease Control (CDC) and Food and Drug Administration (FDA) are reviewing data involving six reported U.S. cases out of more than 6.8 million doses administered. Out of an abundance of caution, the CDC and FDA have recommended a pause in the use of our vaccine. In addition, we have ...
Source: Johnson and Johnson - April 13, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

NICE recommendation for chronic primary pain
People with chronic primary pain should be offered a range of treatments to help them manage their condition, NICE has said in its guideline on the assessment and management of chronic pain published this week. (Source: NHS Networks)
Source: NHS Networks - April 8, 2021 Category: UK Health Source Type: news

NIDCR's Spring 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Spring 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   Grantee News   NIDCR News NIDCR & NIH Stand Against Structural Racism NIDCR Director Rena D’Souza, DDS, MS, PhD, said in a statement that there is no place for structural racism in biomedical research, echoing remarks from NIH Director Francis Collins, MD, PhD, in his announcement of a new NIH ...
Source: NIDCR Science News - April 7, 2021 Category: Dentistry Source Type: news

New Real-World Observational Analysis of UPTRAVI ® (selexipag) Underscores the Importance of Risk Assessment for Treating Pulmonary Arterial Hypertension (PAH) Patients
SOUTH SAN FRANCISCO, CA – April 6, 2021 – Findings from an analysis of the first 500 patients enrolled in the SPHERE registry (SelexiPag: tHe usErs dRug rEgistry) found more than three-quarters (76%) of pulmonary arterial hypertension (PAH) patients treated with UPTRAVI® (selexipag) either maintained (56%) or reduced (20%) their one-year mortality risk score. The SPHERE results were published in the April issue of the Journal of Heart and Lung Transplantation (JHLT). SPHERE is an ongoing real-world, observational, user registry using two different risk assessment methods that describes the clinical characte...
Source: Johnson and Johnson - April 6, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

The effect of the orthopaedic trauma association's (OTA) pain management guidelines on opioid prescriptions, pain control, and refills in outpatient orthopaedic trauma surgery - Chambers L, Jaynstein J, Parry JA, Mauffrey C.
PURPOSE: To determine the effect of the Orthopaedic Trauma Association (OTA) pain management guidelines for acute musculoskeletal injuries on opioid prescription sizes, pain control, and refills. METHODS: A prospective cohort study was performed at... (Source: SafetyLit)
Source: SafetyLit - April 4, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Weekly Postings
See something of interest? Please share our postings with colleagues in your institutions! Spotlight COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from CDC: https://www.coronavirus.gov Get the latest research information from NIH: https://covid19.nih.gov/ Responding to the COVID-19 Infodemic: The Network of the National Library of Medicine (NNLM) is excited to announce a new, free virtual symposium focused on addressing the COVID-19 Infodemic in our communities. Through paper session, panels, and a networking space, symposium attendees can expect to come away from this experi...
Source: NN/LM Middle Atlantic Region Blog - April 2, 2021 Category: Databases & Libraries Authors: Tessa Zindren Tags: Weekly Postings Source Type: news

What Are Indications for a Ileostomy?
Discussion There are three types of inflammatory bowel disease (IBD): Crohn’s disease (CD) – can affect entire gastrointestinal tract but often is discontinuous (i.e., has skipped areas), has transmural inflammation and disease, has granulomas Ulcerative colitis (UC) – affects the colon, is continuous (i.e., has no skipped areas) and has superficial mucosal ulcerations Unclassified IBD – has chronic colitis but not specific features of CD or UC The specific pathogenesis appears to be multifactorial with having a genetic predisposition (1.6 – 30% risk of developing UC if patient has first deg...
Source: PediatricEducation.org - March 29, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Looking back on a year of COVID-19
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Source: Johns Hopkins University and Health Systems Archive - March 25, 2021 Category: Nursing Source Type: news

Janssen Announces U.S. FDA Approval of PONVORY ™ (ponesimod), an Oral Treatment for Adults with Relapsing Multiple Sclerosis Proven Superior to Aubagio® (teriflunomide) in Reducing Annual Relapses and Brain Lesions
TITUSVILLE, N.J. – (March 19, 2021) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) approved PONVORY™ (ponesimod), a once-daily oral selective sphingosine-1-phosphate receptor 1 (S1P1) modulator, to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.1,2,3 PONVORY™ offers MS patients superior efficacy in reducing annualized relapse rates compared to an established oral therapy and a proven safety profi...
Source: Johnson and Johnson - March 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Evaluation of Commercially Available Pain Management Apps Evaluation of Commercially Available Pain Management Apps
This study evaluated 28 commercially available pain management apps, with a focus on their use of evidence-based behavior change techniques.Pain (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 17, 2021 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Digitally Delivered Exercises Benefit Knee Osteoarthritis
MONDAY, March 15, 2021 -- Digitally delivered exercise programs benefit pain and functional outcomes among patients with knee osteoarthritis compared with routine self-management, according to a study published online Feb. 23 in JAMA Network... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 15, 2021 Category: Pharmaceuticals Source Type: news

What Are Generalized Anxiety Disorder Treatment Components?
Discussion Generalized anxiety disorder (GAD) is “…excessive anxiety and worry about a number of events and activities coupled with at least one physical symptom, which may include fatigue, poor concentration, restlessness, irritability, muscle tension, and sleep difficulties.” Other ways it presents to the primary care office may be abdominal pain, headache or heart palpitations, dizziness, syncope, numbness, trembling, paresthesia, memory loss, or urinary frequency. It has an estimated prevalence of 15% and is the second most common anxiety disorder in children after social anxiety disorder. GAD can co...
Source: PediatricEducation.org - March 15, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Unicorn Hinge Health buys electrical stimulation company to reduce back and joint pain
Hinge Health, the musculoskeletal startup valued at $3 billion, has added pain relief management to its arsenal of digital solutions to improve joint and back pain. No, it's not opioid pain pills. It's a nonaddictive electrical stimulation that the company says can reduce joint and back pain when applied to nerves. Hinge Health acquired the technology from fellow San Francisco startup Enso in its first-ever acquisition. Terms were not disclosed. The team at Enso will join Hinge Health. Enso… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - March 12, 2021 Category: Health Management Authors: Brian Rinker Source Type: news

Unicorn Hinge Health buys electrical stimulation company to reduce back and join pain
Hinge Health, the musculoskeletal startup valued at $3 billion valued, has added pain relief management to its arsenal of digital solutions to improve joint and back pain. No, it's not opioid pain pills. It's a nonaddictive electrical stimulation that the company says when applied to nerves can reduce joint and back pain. Hinge Health acquired the technology from fellow San Francisco startup Enso in its first ever acquisition. Terms were not disclosed. The team at Enso will join Hinge Health.… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - March 11, 2021 Category: Biotechnology Authors: Brian Rinker Source Type: news

Pain management and prevention of suicide in the COVID-19 era - Pakniyat-Jahromi S, Sher L.
Pain is a frequent symptom in hospitalised patients and outpatients. Chronic pain is reported to be the most common complaint in primary care setting, affecting more than 100 million people in the USA with an annual cost greater than $635 billion [1]. Many... (Source: SafetyLit)
Source: SafetyLit - March 11, 2021 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news