U.S. FDA Approves TECVAYLI ™ (teclistamab-cqyv), the First Bispecific T-cell Engager Antibody for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma
HORSHAM, Pa., October 25, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) approved TECVAYLI™ (teclistamab-cqyv) for the treatment of adult patients with relapsed or refractory multiple myeloma, who previously received four or more prior lines of therapy, including a proteasome inhibitor, immunomodulatory drug and anti-CD38 monoclonal antibody.1 TECVAYLI™ is a first-in-class, bispecific T-cell engager antibody that is administered as a subcutaneous treatment.1 This off-the-shelf (or ready to use) therapy uses innovative science to ac...
Source: Johnson and Johnson - October 25, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Local interventions for the management of alveolar osteitis (dry socket)
Cochrane Database Syst Rev . 2022 Sep 26;9(9):CD006968. doi: 10.1002/14651858.CD006968. Abstract Background: Alveolar osteitis (dry socket) is a complication of dental extractions more often involving mandibular molar teeth. It is associated with severe pain developing 2 to 3 days postoperatively with or without halitosis, a socket that may be partially or totally devoid of a blood clot, and increased postoperative visits. This is an update of the Cochrane Review first published in 2012. OBJECTIVES: To assess the effects of local interventions used for the prevention and treatment of alveolar osteitis (dry socket) followin...
Source: Dental Technology Blog - October 24, 2022 Category: Dentistry Source Type: news
For Kids with Long COVID, Good Treatment Is Hard to Find
Ayden Varno was outside doing chores one day in April 2021 when he felt an excruciating pain, like “a hot knife was being stabbed into my back multiple times,” he says.
Ayden, who is now 13, spent most of the next eight months in pain so extreme he couldn’t walk unassisted, sleep through the night, or follow a full school curriculum. He also suffered frequent non-epileptic seizures related to his pain. Doctors near his home in Ohio had no idea why Ayden was in so much pain or what to do about it; some suggested he was having a psychotic episode or being abused at home, says his mother, Lynda Varno. The fa...
Source: TIME: Health - October 24, 2022 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 feature healthscienceclimate Source Type: news
How Can a Consultation Be Made Better?
Discussion
Most physicians go into medicine because they like people and want to help them and their families. Clinical patient care can also be fun, interesting, intellectually challenging and provide a creative outlet. All physicians will never know everything and need help with patient care problems that arise. That is when a patient should be referred for a consultation. Effective consultations have several important components which can be overlooked. When clear questions with background information are asked and the consultant provides specific clear recommendations answering the question but also planning for contin...
Source: PediatricEducation.org - October 24, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Should You Tell Your Boss You Have IBD? Plus More Tips for Coping at the Office
As the human resources director for family Destinations Guide, a website that offers kid-friendly vacation ideas, Bonnie Whitfield always makes sure employees feel comfortable disclosing their medical conditions so the company can provide accommodations. For Whitfield, it’s not just professional—it’s personal, because she has inflammatory bowel disease (IBD).
“Since I have IBD myself, and I’ve been through a few flare-ups at work, I know what it’s like to be in that situation,” she says. Employees are often trying to navigate not just the symptoms of a chronic illness, but also anx...
Source: TIME: Health - October 20, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Gut health healthscienceclimate Source Type: news
Opioid-Sparing Protocol Cuts Opioid Use After Arthroscopy
MONDAY, Oct. 17, 2022 -- An opioid-sparing postoperative pain management protocol reduces opioid consumption compared with standard care for patients undergoing outpatient shoulder or knee arthroscopy, according to a study published in the Oct. 4... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 17, 2022 Category: Pharmaceuticals Source Type: news
Blunt chest wall trauma: rib fractures and associated injuries - Beloy V, Dull M.
Blunt injuries to the chest wall, specifically those related to rib fractures, need to be promptly identified and effectively managed to reduce patient morbidity and mortality. Furthermore, judicious use of multimodal pain management and early identificati... (Source: SafetyLit)
Source: SafetyLit - October 13, 2022 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
New Guidance on Acupuncture, Massage, Yoga for Cancer Pain New Guidance on Acupuncture, Massage, Yoga for Cancer Pain
Integrating nonpharmacologic pain management techniques such as acupuncture, hypnosis, and music therapy may help relieve certain types of cancer-related pain, according to new joint guidelines.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 28, 2022 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
B. Braun Acquires Clik-FIX(R) Catheter Securement Devices from Starboard Medical
Acquisition Creates Industry-Leading Portfolio of Catheter Securement Solutions
BETHLEHEM, Pa., Sept. 27, 2022 -- (Healthcare Sales & Marketing Network) -- B. Braun Medical Inc. (B. Braun), a leader in infusion therapy and pain management, announced to... Devices, Acquisitions B. Braun Medical, Starboard Medical, Clik-FIX catheter (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 27, 2022 Category: Pharmaceuticals Source Type: news
Why Overdose Deaths Skyrocketed After Opioid Prescriptions Dropped
The American crackdown on the drugs that kicked off the modern opioid overdose epidemic—prescription opioids—largely succeeded. According to data released by the American Medical Association (AMA) on Sept. 8, opioid prescriptions have dropped in every state over the last decade, plummeting nearly 50% nationally.
The effort to prevent overdose deaths, however, is an abject failure. Annual opioid overdose deaths more than tripled between 2010 and 2020, according to federal data. Drug overdose deaths over a 12-month period surpassed 100,000 for the first time in April 2021, with about 75% of those deaths involving...
Source: TIME: Health - September 19, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized Drugs healthscienceclimate Source Type: news
When is Bruxism Bad?
Discussion
Bruxism “is a masticatory muscle activity that may occur during sleep ([sleep bruxism, SB] characterized as rhythmic or non-rhythmic) and/or wakefulness ([awake bruxism, AB] characterized as repetitive or sustained tooth contact and/or by bracing or thrusting the mandible.)” Bruxism was first described in 1907. Bruxism studies are quite variable in their results given the lack of standardized diagnostic methods.
Patients or family members will often report tooth grinding noises, and on physical examination there will be abnormal tooth wear, tooth mobility, hypertrophy of the masseter muscles and othe...
Source: PediatricEducation.org - September 19, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: a PERUKI service evaluation - Hartshorn S, Durnin S, Lyttle MD, Barrett M.
BACKGROUND: Management of acute pain should commence at the earliest opportunity, as it has many short-term and long-term consequences. A research priority of Paediatric Emergency Research in the UK and Ireland (PERUKI) was to examine paediatric pain pract... (Source: SafetyLit)
Source: SafetyLit - September 5, 2022 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Long-term prescription opioid use after injury in Washington State 2015-2018 - Lyons VH, Haviland MJ, Zhang IY, Whiteside LK, Arbabi S, Vavilala MS, Curatolo M, Rivara FP, Rowhani-Rahbar A.
BACKGROUND: Patients with injury may be at high risk of long-term opioid use due to the specific features of injury (e.g., injury severity), as well as patient, treatment, and provider characteristics that may influence their injury-related pain management... (Source: SafetyLit)
Source: SafetyLit - September 3, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Supporting Primary Prevention
To improve pain management and patient outcomes thereby reducing unnecessary exposures and preventing substance use disorders (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 30, 2022 Category: Drugs & Pharmacology Authors: FDA Source Type: news
How Common is Tongue-Tie?
Discussion
The anterior 2/3s of the tongue is formed from the 2 lateral lingual swellings fusing with the tuberculum impar and then separating from the mouth’s floor to form the lingual sulcus. Separation failure can result in anchoring of the tongue to varying degrees. Frenula are soft tissue structures which attach and support other oral structures. The lingual frenula attaches the tongue to base of mouth. Labial frenula are located centrally and attach the lips to the alveolar ridges. Often less prominent are the buccal frenula which are on the labial side and are smaller and more lateral to the labial frenula, us...
Source: PediatricEducation.org - August 29, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
