Fight Aging! Newsletter, November 27th 2017

We examined associations between mortality and accelerometer-measured PA using age-relevant intensity cutpoints in older women of various ethnicities. The results support the hypothesis that higher levels of accelerometer-measured PA, even when below the moderate-intensity threshold recommended in current guidelines, are associated with lower all-cause and CVD mortality in women aged 63 to 99. Our findings expand on previous studies showing that higher self-reported PA reduces mortality in adults aged 60 and older, specifically in older women, and at less than recommended amounts. Moreover, our findings challenge the conclusion of recent meta-analyses that MVPA, measured by to self-report, is required to offset mortality risk in adults. First, absolute rates of all-cause and cardiovascular disease mortality were at least 50% lower in cohort members in the middle tertile of each PA exposure than in those in the lowest tertile. This is particularly impressive when considering the small mean differences between these tertiles of 50 minutes/day for low light-intensity PA, 33 minutes/day for high light-intensity PA, and 20 minutes/day for MVPA. Use of accelerometers enhanced accurate quantification of such small differences in usual daily PA, which is not possible using questionnaire assessments. Small increases in daily PA, which older adults can achieve, could have a substantial effect on mortality in later life. Even in the oldest cohort members, ages 80-89 and &g...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

Related Links:

Publication date: Available online 18 January 2020Source: Redox BiologyAuthor(s): Mohamad Assi, Suzanne Dufresne, Amélie RébillardAbstractIn this paper of the special issue dedicated for the Olympics 2020, we put the light on an exciting facet of exercise-oncology, which may still be unknown to some audience. Accumulating convincing evidences show that exercise reduces cancer progression and recurrence mainly in colon and breast cancer patients. Interestingly, the positive effects of exercise on cancer outcomes were mainly observed when patients practiced vigorous exercise of 6 METs or more. At the molecular ...
Source: Redox Biology - Category: Biology Source Type: research
Authors: Thomas SP PMID: 31951802 [PubMed - in process]
Source: Issues in Mental Health Nursing - Category: Nursing Tags: Issues Ment Health Nurs Source Type: research
Authors: Bharadwaj AS, Swamy PM, Mamas MA Abstract Introduction: There are numerous shared risk factors in the etiopathogenesis of coronary artery disease (CAD) and cancer both at the epidemiologic and molecular level. Additionally, the different modalities of treatment of cancer such as radiation, chemotherapy, immunotherapy and hormonal therapies further increase the risk of CAD and acute coronary syndrome. Most large database analysis and single center experiences have shown that cancer patients undergoing PCI are at an increased risk of in-hospital mortality, bleeding repeat revascularization.Areas covered: In ...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
Authors: Al-Obaidy KI, Chovanec M, Cheng L PMID: 31951790 [PubMed - as supplied by publisher]
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
Conclusions: Salvage chemotherapy (often with rituximab and radiotherapy), followed by HDT and stem cell transplantation, appears to be the standard real-world treatment for rrPMBCL. However, large prospective and retrospective studies are warranted to improve our knowledge of real-world treatment patterns. PMID: 31951774 [PubMed - as supplied by publisher]
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research
Conclusion: DCP ischemia may improve after aflibercept treatment. Central macular vessel density was found to decrease post-treatment, but the clinical relevance needs further investigation. PMID: 31951761 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
Authors: Annibale B, Esposito G, Lahner E Abstract SUMMARYIntroduction: Atrophic gastritis (AG) is a complex syndrome which arise as consequence of H. pylori infection or in the context of gastric autoimmunity. It often deserves a benign course, but may lead to potentially life-threatening complications: cancer and anaemia. This review aims to address traditional and innovative knowledge on this often under-diagnosed disorder.Areas covered: This review covers clinical presentation, risk factors, diagnosis and management of AG and provides an updated resource for clinicians to get insight in this challenging disorde...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
We have a total of 42 ICU beds in our community hospital. Acuity is high as we have a large catchment area and we serve as a referral site for surrounding hospitals. Trauma center and comprehensive stroke center. Trying to see how we could make things better. Currently we have 2 intensivists and 1 NP/PA on days. Open ICU and we see everyone on the vent and on vasoactive agents plus others if we are asked to help. We do multidis rounds on every patient in the unit, regardless of whether we... How is your ICU staffed?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Critical Care Source Type: forums
ConclusionFor advanced endometrial cancer patients, surgery in addition to chemotherapy confers a survival advantage except when optimal debulking cannot be achieved.
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
TERMINALLY-ILL cancer patients are stunning medical experts by getting the all-clear after being given an NHS therapy dubbed “the Lazarus treatment”. The “transformational” form of immunotherapy reprogrammes the immune system so that it destroys the cancer, with tumours shrinking within days.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
More News: Academia | Accidents | Alzheimer's | Amyloidosis | Babies | Babies Heart Conditions | Biochemistry | Biology | Biotechnology | Brain | Brain Cancers | Calcium | Cancer | Cancer & Oncology | Cancer Vaccines | Cardiology | Cardiovascular | Chemistry | Cholesterol | Chronic Obstructive Pulmonary | Clinical Trials | Dementia | Depression | Diabetes | Diets | Eating Disorders & Weight Management | Endocrinology | Environmental Health | Epidemiology | Eyes | Fortamet | Gastroschisis Repair | Genetics | Germ Cell Tumors | Heart | Heart Attack | Heart Transplant | Hemorrhoids | High Fat | History of Medicine | Hormones | Hypertension | Infectious Diseases | Influenza | Influenza Vaccine | Information Technology | Insulin | Insurance | Insurers | International Medicine & Public Health | Israel Health | Laboratory Medicine | Learning | Liver | Liver Transplant | Lung Transplant | Men | Metabolic Syndrome | Metformin | Mitochondria | Mitochondrial Disease | Molecular Biology | Neurology | Neuroscience | Nutrition | Obesity | Oral Cancer | Orthopaedics | Osteoarthritis | Osteoporosis | Pathology | Pharmaceuticals | Pneomococcal Vaccine | Pneumonia | Polio | Polio Vaccine | Reclast | Reproduction Medicine | Research | Respiratory Medicine | Science | Skin | Smallpox | Smallpox Vaccine | Smokers | Sports Medicine | Statin Therapy | Stem Cell Therapy | Stem Cells | Stroke | Study | Toxicology | Transplants | Tuberculosis | Universities | Universities & Medical Training | Urology & Nephrology | Vaccines | Veterinary Vaccinations | Women | Zometa