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New treatment for osteoporosis provides better protection against fractures
(University of Gothenburg) A new treatment for osteoporosis provides major improvements in bone density and more effective protection against fractures than the current standard treatment. These are the findings of a study published in the New England Journal of Medicine (NEJM). The study is the first that compares the effect of two osteoporosis medicines on fractures. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 19, 2017 Category: International Medicine & Public Health Source Type: news

Four New Things About Osteoporosis
(MedPage Today) -- What the latest studies say about the bone condition (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - September 16, 2017 Category: Primary Care Source Type: news

How Do You Treat a Spine Fracture from Osteoporosis?
Title: How Do You Treat a Spine Fracture from Osteoporosis?Category: Doctor's& Expert's views on SymptomsCreated: 9/15/2017 12:00:00 AMLast Editorial Review: 9/15/2017 12:00:00 AM (Source: MedicineNet Senior Health General)
Source: MedicineNet Senior Health General - September 15, 2017 Category: Geriatrics Source Type: news

Cost Efficacy of Drugs for Treatment of Osteoporosis Cost Efficacy of Drugs for Treatment of Osteoporosis
Which of the available pharmacologic treatment options for osteoporosis is the most cost-effective?Endocrine Practice (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 15, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Osteoporosis breakthrough: positive news in a field plagued by bad press
A new study has shown that the use of a common osteoporosis drug with anti-inflammatory medication is linked to a lower risk of hip fracture. This is just one of a range of exciting developments in the field, which also include the approval of a new … (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - September 13, 2017 Category: Pharmaceuticals Source Type: news

Why Hormone Replacement Therapy May Be Safer Than You Think
The pendulum has swung from one extreme to the other when it comes to hormone replacement therapy (HRT) to treat symptoms of menopause. At first, the replacement hormones—mostly a combination of estrogen and progestin to replace what the body stops making after menopause—were seen as a panacea. Doctors thought they could not only relieve hot flashes and night sweats, but also prevent chronic aging diseases like heart problems and weakening bones. But studies then found that the supplement hormones could lead to a higher risk of breast cancer—and that they didn’t protect the heart after all. In the l...
Source: TIME.com: Top Science and Health Stories - September 12, 2017 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs estrogen Hormone Therapy hormones for menopause hot flashes night sweats progestin Reproductive Health treating menopause Source Type: news

Abaloparatide Fracture Reductions Sustained in Osteoporosis Abaloparatide Fracture Reductions Sustained in Osteoporosis
Final results from the ACTIVExtend trial show sustained reductions with the osteoanabolic drug for 2 years after switching to a bisphosphonate, an effect that one expert commented is"impressive."Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 12, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Gene variants newly linked to osteoporosis
A link between the loss of bone mineral density that can result in osteoporosis-related fractures and 153 new gene variants has been found, according to a genome-wide association study published inNature Genetics.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 12, 2017 Category: Endocrinology Source Type: news

Sequential therapy a winner in osteoporosis
The administration of abaloparatide (Tymlos) for 18 months followed by alendronate (Fosamax) for 2 years was associated with dramatic reductions in fracture risk among postmenopausal women, according to research presented at the American Society for Bone and Mineral Research annual meeting.Medpage Today (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 12, 2017 Category: Endocrinology Source Type: news

The 8 WORST pieces of advice medical doctors give their patients
(Natural News) Just one century ago in America, all of the most popular chronic diseases and disorders that we know so well today barely existed, including cancer, diabetes type 2, Alzheimer’s, arthritis, osteoporosis, Parkinson’s and heart disease. Still, nearly every medical doctor in the United States blames hereditary genes for these preventable health problems, as... (Source: NaturalNews.com)
Source: NaturalNews.com - September 12, 2017 Category: Consumer Health News Source Type: news

Romosozumab Associated with Lower Osteoporotic Fracture Risk than Alendronate (FREE)
By Joe Elia Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Romosozumab outperformed alendronate in lowering osteoporosis-related fracture risk, according to an industry-conducted, phase 3 study published in the New … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 12, 2017 Category: Primary Care Source Type: news

Sequential Therapy a Winner in Osteoporosis (CME/CE)
(MedPage Today) -- Feasible to start with an anabolic drug and then give antiresorptive (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - September 11, 2017 Category: Primary Care Source Type: news

Extended DXA, Risk Factors, Predict AFF With Bisphosphonate Use Extended DXA, Risk Factors, Predict AFF With Bisphosphonate Use
Two new studies indicate novel ways to help identify or predict the small percentage of osteoporosis patients using bisphosphonates who will be adversely affected by atypical femoral fractures.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 11, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Osteoporosis Drug Use in Chronic Kidney Disease Osteoporosis Drug Use in Chronic Kidney Disease
The study shows improved bone mineral density with oral bisphosphonates in those with moderate or severe CKD.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 9, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Hyponatremia, bone mineral density and falls in the elderly; results from AHAP study - Hosseini SR, Baghitabar N, Mirzapour A, Oliaei F, Nooreddini H, Bijani A, Mouodi S.
BACKGROUND: Hyponatremia (HN) can be associated with osteoporosis, falls and bone fractures in the elderly. Recent researches demonstrated different results about the correlation of HN with bone mineral density and bone fractures. METHODS: This ana... (Source: SafetyLit)
Source: SafetyLit - September 8, 2017 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Amgen Highlights The Latest EVENITY ™ (Romosozumab) And Prolia® (Denosumab) Research At The American Society For Bone And Mineral Research Annual Meeting
First Presentation of Detailed EVENITY ARCH Study Results and FRAME Extension Final Analysis 10-Year Data From Long-Term Prolia FREEDOM Study THOUSAND OAKS, Calif., Sept. 8, 2017 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that 19 scientific abstracts will highlight the latest scientific research on EVENITY™* (romosozumab) and Prolia® (denosumab) at this year's Annual Meeting of the American Society for Bone and Mineral Research (ASBMR) in Denver from Sept. 8-11, 2017. "The data being presented at ASBMR underscore our steadfast focus for more than a decade to advance scientific unders...
Source: Amgen News Release - September 8, 2017 Category: Pharmaceuticals Tags: Uncategorized Source Type: news

Osteoporosis cure on the horizon: Discovery could lead to NEW treatment for symptoms
OSTEOPOROSIS is a condition which causes the bones to weaken and become less dense and can increase the risk of fractures. However, now experts believe a new drug to treat the condition could be on the horizon. (Source: Daily Express - Health)
Source: Daily Express - Health - September 8, 2017 Category: Consumer Health News Source Type: news

Under-reporting of vertebral fractures by radiologists: A missed opportunity
(International Osteoporosis Foundation) A new retrospective study by researchers at the University of Oxford has found that within a cohort of hip fracture patients many had previous imaging studies showing incidental vertebral fractures -- but 54 percent of the vertebral fractures were not reported by radiologists. The study puts a spotlight on the under-reporting of osteoporotic vertebral fractures, particularly by radiologists who are not specialized in musculoskeletal imaging. This is a missed opportunity to prevent subsequent, often life-threatening hip fractures. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 8, 2017 Category: International Medicine & Public Health Source Type: news

Osteoporosis gene study reveals potential new treatment targets
Scientists have identified a number of new genetic variants that are implicated in the development ofosteoporosis following a major study. The research, led by the University of Queensland in Australia and McGill University in Canada, have carried out the largest ever genetic study of osteoporosis, with their findings potentially paving the way for new approaches to treating the bone disease. A broad-ranging study The study was published in the medical journal Nature Genetics and analysed data from more than 140,000 individuals from the UK Biobank, with bone mineral density assessments taken from ultrasounds of the heel. A...
Source: Arthritis Research UK - September 7, 2017 Category: Rheumatology Source Type: news

Hip fracture often deadly, Australian study shows
(International Osteoporosis Foundation) This is the first large population-based matched cohort study exploring excess mortality risk from hip fracture in the Australian population while accounting for pre-injury comorbid conditions. It finds that hip fracture sufferers experienced significantly worse survival at 12-months post-fracture. Individuals with hip fracture were more than 3.5 times more likely to die within 12 months compared to their non-injured counterpart, and excess mortality was higher in men than in women. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 7, 2017 Category: International Medicine & Public Health Source Type: news

Largest ever genetic study paves way for potential osteoporosis treatment
A large genome-wide association study, published inNature Genetics, has identified novel, potential treatment targets for osteoporosis.News Medical (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 6, 2017 Category: Endocrinology Source Type: news

Is eating chocolate making my acid reflux worse?
The Daily Mail's resident GP addresses your latest health concerns, from the flip-side of sweet treats to osteoporosis. (Source: the Mail online | Health)
Source: the Mail online | Health - September 4, 2017 Category: Consumer Health News Source Type: news

Osteoporosis cure? Woman reveals THIS treatment has REVERSED her symptoms
OSTEOPOROSIS is a condition which causes the bones to decrease in density - which puts people at greater risk of bone fractures. (Source: Daily Express - Health)
Source: Daily Express - Health - September 4, 2017 Category: Consumer Health News Source Type: news

Incidence of bone protection and associated fragility injuries in patients with proximal femur fractures - Aguado-Maestro I, Panteli M, Garcia-Alonso M, Ba ñuelos-Díaz A, Giannoudis PV.
OBJECTIVES: Our aim was to investigate whether patients presenting with fragility fractures of the proximal femur are receiving osteoporosis treatment and to assess the number of other fragility fractures they have sustained prior to admission. MET... (Source: SafetyLit)
Source: SafetyLit - September 1, 2017 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

New osteoporosis treatment uses traditional Chinese herb to prevent bone loss
(University of British Columbia) An herb widely used in traditional Chinese medicine might hold the key to a new osteoporosis therapy that could prevent bone loss without causing side effects. Using a compound derived from red sage, UBC researchers have found a way to selectively block an enzyme called Cathepsin K (CatK), which plays a major role in the breakdown of collagen in bones during osteoporosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 29, 2017 Category: International Medicine & Public Health Source Type: news

Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling
Cytoskeletal reorganization in osteoclasts to form actin rings is necessary for these cells to attach to bone and resorb bone matrices. We delineated the pathway through which Wnt5a signaling through receptor tyrosine kinase–like orphan receptor 2 (Ror2) promoted the bone-resorbing activity of osteoclasts. Wnt5a binding to Ror2 stimulated Rho, a small GTPase involved in cytoskeletal reorganization. Subsequently, the Rho effector kinase Pkn3 bound to and enhanced the activity of c-Src, a nonreceptor tyrosine kinase that is critical for actin ring formation. Mice with an osteoclast-specific deficiency in Ror2 (Ror2Ocl/...
Source: Signal Transduction Knowledge Environment - August 29, 2017 Category: Science Authors: Uehara, S., Udagawa, N., Mukai, H., Ishihara, A., Maeda, K., Yamashita, T., Murakami, K., Nishita, M., Nakamura, T., Kato, S., Minami, Y., Takahashi, N., Kobayashi, Y. Tags: STKE Research Articles Source Type: news

Simple OST Beats FRAX for Osteoporosis Prescreening in Men Simple OST Beats FRAX for Osteoporosis Prescreening in Men
The Osteoporosis Self-Assessment Tool (OST) performs better than a more complicated, web-based Test Fracture Risk Assessment (FRAX) tool for selecting which older men to screen for osteoporosis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 24, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Osteoporosis diet: These five foods could PREVENT weak bones
OSTEOPOROSIS could be prevented through diet. These five foods are among the best for keeping your bones strong. (Source: Daily Express - Health)
Source: Daily Express - Health - August 24, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Osteoporosis: Potential new drug target uncovered
A new study finds that targeting the body's aging-related cells maintains and increases bone formation and improves bone mass and strength in aging mice. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 21, 2017 Category: Consumer Health News Tags: Bones / Orthopedics Source Type: news

PPMD's Bone Health Workshop Published
Bone health has long been a confusing and often neglected aspect of Duchenne care. There is very little knowledge of underlying bone health in Duchenne, which is further complicated by the possible effects of glucocorticoids on both bone development and bone density/strength. We applaud the incredible work of this group of experts who participated in PPMD's Bone Health Workshop, and hope that, with increased awareness, further work to prevent osteoporosis and enhance bone health in people living with Duchenne will continue. (Source: Parent Project Muscular Dystrophy)
Source: Parent Project Muscular Dystrophy - August 18, 2017 Category: Neurology Source Type: news

Tanzania: Doctors Warn of Chronic Conditions
[Citizen] Dodoma -Doctors here have warned of increasing cases of diseases such as cardiac ailments, prostate cancer, eye diseases and those that affect the bones, known as osteoporosis. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 17, 2017 Category: African Health Source Type: news

Lower back pain? THIS medication could be ineffective and cause side effects
LOWER back pain can be extremely debilitating - caused by everything from poor posture, slipped discs, sciatica and osteoporosis. (Source: Daily Express - Health)
Source: Daily Express - Health - August 16, 2017 Category: Consumer Health News Source Type: news

Osteoporosis Care for RA Patients Found Suboptimal, Declining (CME/CE)
(MedPage Today) -- Results of large observational study (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - August 13, 2017 Category: Consumer Health News Source Type: news

Living With Cancer: Chair Yoga for My Funny Bones
Radiation, chemotherapy and steroids can render bones brittle, something I learned after I slipped on ice and fractured my pelvis. (Source: NYT Health)
Source: NYT Health - August 10, 2017 Category: Consumer Health News Authors: SUSAN GUBAR Tags: Osteoporosis Chemotherapy Steroids Radiation Cancer Bones Source Type: news

It's Never Too Soon to Safeguard Your Bones
Osteoporosis prevention starts now Source: HealthDay Related MedlinePlus Pages: Bone Density, Osteoporosis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - August 9, 2017 Category: Consumer Health News Source Type: news

It's Never Too Soon to Safeguard Your Bones
WEDNESDAY, Aug. 9, 2017 -- Bone health is literally something you build on throughout your life, not just as a child. And the efforts you put in now will keep bones strong and help prevent the bone-thinning disease osteoporosis later on, as you... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 9, 2017 Category: General Medicine Source Type: news

Latest research on osteoporosis and bone health at ASBMR 2017 Annual Meeting - Sept. 8-11, Denver
(Burness) Thousands of bone scientists will come together for the American Society for Bone and Mineral Research (ASBMR) 2017 Annual Meeting, the premier scientific meeting in the world on bone, mineral and musculoskeletal science, to present their latest research and collaborate on new opportunities to increase the testing, diagnosis and treatment options. Special Session: Reducing the Treatment Gap on Osteoporosis (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 9, 2017 Category: Cancer & Oncology Source Type: news

Prostate Cancer Patients Can Improve Bone Health With Osteoporosis Medications
Men with non-metastatic prostate cancer who receive androgen deprivation therapy risk loss of bone mineral density and fractures, but both bisphosphonates and denosumab can improve their bone health. (Source: CancerNetwork)
Source: CancerNetwork - August 8, 2017 Category: Cancer & Oncology Authors: Mark L. Fuerst Tags: Genitourinary Cancers News Prostate Cancer Source Type: news

Osteoporosis Meds Up BMD in Nonmetastatic Prostate Cancer
Review shows improved bone mineral density in men receiving androgen deprivation therapy (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - August 8, 2017 Category: Cancer & Oncology Tags: Internal Medicine, Oncology, Orthopedics, Pharmacy, Urology, Journal, Source Type: news

Osteoporosis medications improve bone health in men being treated for prostate cancer
(American College of Physicians) Both biophosphonates and denosumab improve bone mineral density in men with nonmetastatic prostate cancer who are receiving androgen deprivation therapy. The results from a systematic review and meta-analysis are published in Annals of Internal Medicine. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 7, 2017 Category: Cancer & Oncology Source Type: news

Osteoporosis Drug Use Falls Short
(MedPage Today) -- Only about one in five postmenopausal women received appropriate meds (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 6, 2017 Category: Primary Care Source Type: news

FDA Drug Safety Communication: Ongoing safety review of oral osteoporosis drugs (bisphosphonates) and potential increased risk of esophageal cancer
[07-21-2011] The U.S. Food and Drug Administration (FDA) is continuing to review data from published studies to evaluate whether use of oral bisphosphonate drugs is associated with an increased risk of cancer of the esophagus (esophageal cancer). (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 4, 2017 Category: Drugs & Pharmacology Source Type: news

What Are the Best Exercises for Osteoporosis?
Title: What Are the Best Exercises for Osteoporosis?Category: Doctor's& Expert's views on SymptomsCreated: 8/4/2017 12:00:00 AMLast Editorial Review: 8/4/2017 12:00:00 AM (Source: MedicineNet Senior Health General)
Source: MedicineNet Senior Health General - August 4, 2017 Category: Geriatrics Source Type: news

FDA Drug Safety Communication: Possible increased risk of fractures of the hip, wrist, and spine with the use of proton pump inhibitors
Update: 3/23/2011 FDA has determined an osteoporosis and fracture warning on the over-the-counter (OTC) proton pump inhibitor (PPI) medication “Drug Facts” label is not indicated at this time. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Gym workout: Five exercises that can help prevent a hip replacement
GYM workouts may often be for aesthetics, but increasingly they ’re being enlisted to boost mental health, functional fitness and even ward off particular conditions, such as osteoporosis. (Source: Daily Express - Health)
Source: Daily Express - Health - August 3, 2017 Category: Consumer Health News Source Type: news

FDA Drug Safety Communication: Safety update for osteoporosis drugs, bisphosphonates, and atypical fractures
[10-13-2010] The U.S. Food and Drug Administration (FDA) is updating the public regarding information previously communicated describing the risk of atypical fractures of the thigh, known as subtrochanteric and diaphyseal femur fractures, in patients who take bisphosphonates for osteoporosis. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Bone loss after denosumab, only partial protection with zoledronate
This report investigates whether a single infusion of zoledronate might also be an effective option to prevent bone loss after long-term denosumab treatment in postmenopausal patients is discontinued. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 2, 2017 Category: International Medicine & Public Health Source Type: news

Osteoporosis drugs could make fractures more likely
Taking biphosphonates for more than five years alters the composition of bone - making it more brittle, according to the latest study by researchers at Cornell University in New York. (Source: the Mail online | Health)
Source: the Mail online | Health - August 1, 2017 Category: Consumer Health News Source Type: news

Osteoporosis drug 'could make bones MORE brittle if used for longer than five years'
DRUGS used to combat the misery of osteoporosis could increase patients ’ risk of suffering serious fractures, scientists warned last night. (Source: Daily Express - Health)
Source: Daily Express - Health - July 31, 2017 Category: Consumer Health News Source Type: news

Amgen Submits Supplemental Biologics License Application For Prolia ® (denosumab) In Glucocorticoid-Induced Osteoporosis
THOUSAND OAKS, Calif., July 31, 2017 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) for Prolia® (denosumab) for the treatment of patients with glucocorticoid-induced osteoporosis (GIOP).The sBLA is based on a Phase 3 study evaluating the safety and efficacy of Prolia compared with risedronate in patients receiving glucocorticoid treatment. Osteoporosis can be caused by glucocorticoid medications, which are prescribed to treat inflammatory diseases. Within the first three months of beginning ...
Source: Amgen News Release - July 31, 2017 Category: Pharmaceuticals Tags: Uncategorized Source Type: news