Using deep learning with CT helps predict hip fractures
A deep-learning model that includes digital x-rays reconstructed from 3D hip CT images shows promise for predicting subsequent fractures in patients with a relatively recent hip break, researchers have found.
The findings could improve how clinicians care for their patients, wrote a team led by doctoral candidate Yisak Kim of Seoul National University Graduate School in South Korea. The group's findings were published January 30 in Radiology.
"Developing a prediction model for short-term subsequent fracture risk is important because it would identify patients at the highest risk and aid in determining appropriate treatme...
Source: AuntMinnie.com Headlines - January 31, 2024 Category: Radiology Authors: Kate Madden Yee Tags: Clinical News Subspecialties CT Digital X-Ray Musculoskeletal Radiology Source Type: news
Do'Forever Chemicals' Affect Bone Health in Youth? Do'Forever Chemicals' Affect Bone Health in Youth?
Researchers have been asking whether man-made chemicals known as per- and polyfluoroalkyl substances (PFAS) impair bone development in adolescence and predispose adults to osteoporosis.Medscape Diabetes & Endocrinology (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - January 26, 2024 Category: Endocrinology Tags: Diabetes & Endocrinology Commentary Source Type: news
Lithium treatment may promote bone health in women with bipolar disorder
Women taking lithium for bipolar disorder had greater bone mineral density on dual-energy x-ray absorptiometry (DEXA) exams compared to women with bipolar disorder not taking the medication, according to a recent study.The finding reinforces the role of lithium as a first-line therapy, with recent research suggesting that patients with bipolar disorder are disproportionately affected by osteoporosis and have an increased risk of fracture, noted first author Lana Williams, PhD, of Deakin University in Victoria, Australia, and colleagues.“Both the condition and the medications used to treat it, for example, antipsychotics ...
Source: AuntMinnie.com Headlines - January 26, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Digital X-Ray Musculoskeletal Radiology Source Type: news
Denosumab Linked to Severe Hypocalcemia in Dialysis-Dependent Seniors
THURSDAY, Jan. 25, 2024 -- For female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or very severe hypocalcemia, according to a study published online Jan.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 25, 2024 Category: Pharmaceuticals Source Type: news
Obstructive Sleep Apnea May Promote Early Bone Loss Obstructive Sleep Apnea May Promote Early Bone Loss
Evidence of increased bone loss in patients with severe obstructive sleep apnea supported the potential role of sleep-related hypoxemia on osteoporosis.Medscape Medical News (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - January 25, 2024 Category: Orthopaedics Tags: Pulmonary Medicine Source Type: news
RUTH SUNDERLAND is so fit she runs four miles to the office every day. But after a broken shoulder led to a shock osteoporosis diagnosis, she declares... I'm the proof it isn't just an old ladies' disease
RUTH SUNDERLAND: Of all the things to change my life, I didn't expect it to be a gnarly, dusty old tree root. But when I tripped over it training, it was a small misstep with big consequences. (Source: the Mail online | Health)
Source: the Mail online | Health - January 20, 2024 Category: Consumer Health News Source Type: news
FDA Adds Warning to Osteoporosis Drug for Hypocalcemia Risk FDA Adds Warning to Osteoporosis Drug for Hypocalcemia Risk
Based on a completed data review, the agency concluded that denosumab increases the risk for severe hypocalcemia in patients with chronic kidney disease.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - January 19, 2024 Category: Internal Medicine Tags: Nephrology Source Type: news
Amgen's Blockbuster Osteoporosis Drug Prolia Flagged With FDA Strictest Warning
The FDA has added a serious warning to the prescribing information for Amgen Inc’s AMGN drug Prolia (denosumab), emphasizing an increased risk of severely low calcium levels in specific patient groups. Amgen’s Prolia, initially approved in 2010 for treating bone loss in postmenopausal women and…#fda #amgenincs #prolia #amgen #merckcoincs #mrkfosamax #xgeva #evenity #lungcancer (Source: Reuters: Health)
Source: Reuters: Health - January 19, 2024 Category: Consumer Health News Source Type: news
FDA Slaps Boxed Warning on Osteoporosis Drug
(MedPage Today) -- The FDA added a boxed warning to the label of the osteoporosis drug denosumab (Prolia) over the risk of severe hypocalcemia in patients with advanced chronic kidney disease (CKD), the agency announced Friday.
After a review... (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - January 19, 2024 Category: Endocrinology Source Type: news
Prolia (denosumab): Drug Safety Communication - FDA Adds Boxed Warning for Increased Risk of Severe Hypocalcemia in Patients with Advanced Chronic Kidney Disease
FDA Adds Boxed Warning for Increased Risk of Severe Hypocalcemia in Patients with Advanced Chronic Kidney Disease Taking Osteoporosis Medicine Prolia (Denosumab): FDA Safety Communication. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 19, 2024 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Calcium Levels Quickly Become Critical for Many Denosumab-Treated Women on Dialysis
(MedPage Today) -- Many women on dialysis quickly developed severe hypocalcemia after starting denosumab (Prolia) for osteoporosis, Medicare data showed.
During the first 12 weeks of treatment, 41.1% of women on denosumab developed severe hypocalcemia... (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - January 19, 2024 Category: Endocrinology Source Type: news
Children living near green spaces ‘have stronger bones’
Bone strength is set in childhood so better park access could prevent fractures in older people, study findsChildren with more green space near their homes have significantly stronger bones, a study has found, potentially leading to lifelong health benefits.Scientists found that the children living in places with 20-25% more natural areas had increased bone strength that was equivalent to half a year ’s natural growth.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - January 13, 2024 Category: Science Authors: Damian Carrington Environment editor Tags: Access to green space Children's health Society Medical research Science Belgium Europe Environment Osteoporosis Osteoarthritis World news & wellbeing Life and style Mental health Source Type: news
High body fat raises fracture risk in women treated for breast cancer
Women with high body fat undergoing early breast cancer treatment may be at higher risk for vertebral fractures, despite the use of bone health drugs, according to a study published January 10 in JAMA Network Open.
In a study of patients who received aromatase inhibitors and denosumab over four years, dual-energy x-ray absorptiometry (DEXA) scans showed that high baseline fat body mass was independently associated with vertebral fractures after 18 months, wrote lead author Deborah Cosentini, MD, of the University of Brescia in Italy, and colleagues.
“These findings suggest that fat body mass may promote skeletal fragil...
Source: AuntMinnie.com Headlines - January 12, 2024 Category: Radiology Authors: Will Morton Tags: Digital X-Ray Womens Imaging Source Type: news
Prevalence, incidence of and risk factors for vertebral fracture in the community: the Vietnam Osteoporosis Study - Nguyen HT, Nguyen BT, Thai THN, Tran AV, Nguyen TT, Vo T, Mai LD, Tran TS, Nguyen TV, Ho-Pham LT.
The epidemiology of vertebral fractures (VF) in underrepresented populations is not well-documented. This cohort study was part of a longitudinal osteoporosis research project with the aim of determining the prevalence, incidence, and risk factors for VF. ... (Source: SafetyLit)
Source: SafetyLit - January 8, 2024 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Bone health a concern among lung transplant patients
In this study, the group thus evaluated the impact of a multidisciplinary bone health assessment and treatment protocol in patients treated at their transplant clinic at UNC Health in Chapel Hill. The protocol included multidisciplinary team education, initiation of DEXA screening at prespecified intervals post-transplant, and assessment of adequate calcium and vitamin D supplementation.The study included 58 lung transplant recipients: 38 in the preprotocol and 20 in the postprotocol groups, with measurements compared between the patients at two years post-transplant.According to the findings, patients in the postprotocol ...
Source: AuntMinnie.com Headlines - January 3, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Digital X-Ray Musculoskeletal Radiology Source Type: news
