History of Neurodevelopmental Disorders Linked to Seminoma
WEDNESDAY, May 10, 2023 -- Having a history of neurodevelopmental disorders is associated with an increased risk for testicular germ cell tumors (TGCTs), according to a study published online April 24 in the British Journal of Cancer. Anna K.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 10, 2023 Category: Pharmaceuticals Source Type: news

What Causes Mediastinal Masses?
Discussion The mediastinum resides in the chest and is the space bounded by the thoracic inlet cephalically, diaphragm caudally, sternum anteriorly and transverse process of the spine posteriorly, and mediastinal pleura and lungs laterally. It is divided into various compartments: Superior mediastinum Bounded by the thoracic inlet cephalically and a horizontal plane passing from the manubriosternal joint to the junction of T4/T5 vertebrae horizontally. Structures include: esophagus, trachea, parts of great vessels and first branches, great veins and initial branches, thymus, vagus, phrenic and other nerves, thoracic duct...
Source: PediatricEducation.org - February 20, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

What Causes Childhood Extracranial Germ Cell Tumors?
Title: What Causes Childhood Extracranial Germ Cell Tumors?Category: Diseases and ConditionsCreated: 4/5/2022 12:00:00 AMLast Editorial Review: 4/5/2022 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - April 5, 2022 Category: Cancer & Oncology Source Type: news

Diagnostic Radiation May Up Risk for Testicular Cancer
MONDAY, Nov. 16, 2020 -- The risk for testicular germ cell tumor (TGCT) is elevated in association with increased exposure to lower abdominal and pelvic diagnostic radiation, according to a study published online Nov. 11 in PLOS ONE. Kevin T. Nead,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 16, 2020 Category: Pharmaceuticals Source Type: news

Standardized Treatment Improves Outcomes in Germ Cell Tumors
Outcomes similar for patients treated at public safety net hospital, academic tertiary care center (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - August 10, 2020 Category: Cancer & Oncology Tags: Oncology, Urology, Journal, Source Type: news

Standardized Treatment Improves Outcomes in Germ Cell Tumors
MONDAY, Aug. 10, 2020 -- Clinical outcomes are similar for patients receiving standardized treatment for germ cell tumors (GCTs) at a public safety net hospital or an academic tertiary care center, according to a study published online Aug. 10 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 10, 2020 Category: Pharmaceuticals Source Type: news

Tumor Markers'Valuable' for Relapse Detection in Rare CNS Tumors Tumor Markers'Valuable' for Relapse Detection in Rare CNS Tumors
The markers can be used to detect relapse with a high degree of sensitivity in patients with CNS nongerminomatous germ cell tumors, according to a pooled analysis of cooperative group trials.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 29, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Testicular Germ Cell Tumor Incidence Increased for All Races/Ethnicities
FRIDAY, May 8, 2020 -- From 2001 to 2016, the incidence of testicular germ cell tumors increased across all racial/ethnic groups but remained highest among non-Hispanic whites (NHWs), according to a study published online May 8 in Cancer... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 8, 2020 Category: Pharmaceuticals Source Type: news

Study Shows Efficacy of Single-Cycle BEP in Preventing Testicular Cancer Recurrence
Results of this phase III trial could change the current standard of care for treating nonseminomatous or combined germ cell tumors of the testis. (Source: CancerNetwork)
Source: CancerNetwork - January 8, 2020 Category: Cancer & Oncology Authors: Kevin Wright Source Type: news

One-Cycle BE500P Seems Safe for High-Risk Early Testicular Cancer
MONDAY, Jan. 6, 2020 -- For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m ²), and cisplatin (BE500P) is safe, resulting in a two-year malignant recurrence (MR) rate of 1.3... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 6, 2020 Category: Pharmaceuticals Source Type: news

Variant Identified for Testicular Cancer Signals Heightened Risk for Later Cancers
Researchers identified two germline pathogenic variants in CHEK2 that may account for a minority of men diagnosed with testicular germ cell tumors. (Source: CancerNetwork)
Source: CancerNetwork - February 13, 2019 Category: Cancer & Oncology Authors: Christina Bennett, MS Source Type: news

Tumor Markers Limit Imaging Need in Germ-Cell Tumor Surveillance Tumor Markers Limit Imaging Need in Germ-Cell Tumor Surveillance
Tumor markers are a sensitive, radiation-sparing means of surveillance in children and adolescents with malignant germ-cell tumors, according to a retrospective review.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 17, 2019 Category: Consumer Health News Tags: Medscape Today News Source Type: news

What is the Odds Ratio for Testicular Cancer after Cryptorchidism?
Discussion Cryptorchidism is the failure of one or both testes to descend from the abdomen into the scrotum. Congenital undescended testis (UDT)is common in young infants (1-4% in term infants and 45% in preterm infants) in that the testes will be palpable but remain high, but most testes will descend by 3-6 months and by 9 months of age only 1% remain undescended. The scrotum often appears underdeveloped. Sometimes the testes cannot be identified and is intra-abdominal at birth. Intra-abdominal testes are less likely to migrate to the scrotum and therefore are more likely to remain undescended. Acquired undescended test...
Source: PediatricEducation.org - October 15, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Epidemiology and Treatment Trends in Testicular Cancer Epidemiology and Treatment Trends in Testicular Cancer
What are the recent trends in the incidence and treatment patterns of testicular germ cell tumors?Current Opinion in Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 14, 2018 Category: Consumer Health News Tags: Urology Journal Article Source Type: news

Researchers map the genome of testicular cancer
(UNC Lineberger Comprehensive Cancer Center) In a collaborative, multi-institution effort to map the genetic and genomic changes in cancer, researchers led by UNC Lineberger Comprehensive Cancer Center's Katherine Hoadley, Ph.D., analyzed 137 testicular germ cell tumors for potential mutations and other molecular changes. They identified molecular features of testicular germ cell cancers that could inform future efforts to improve treatment decisions, and help monitor patients to see if their cancer has come back. Their findings were published in Cell Reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 12, 2018 Category: International Medicine & Public Health Source Type: news