Mirimus' RNAi Technology Helps Advance New Treatment for Liver Tumors and Acute Chronic Liver Diseases
Leveraging Mirimus RNAi technology, a study led by Tuebingen University shows that a new drug has the potential to revolutionize liver surgery and liver transplantation. NEW YORK, March 18, 2024 /PRNewswire-PRWeb/ -- Mirimus, a pioneer in RNAi therapeutic design and CRISPR/Cas9 gene... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - March 18, 2024 Category: Pharmaceuticals Tags: TRI Source Type: news

Chinese Scientists Implant First Pig Liver Into Brain-Dead Human
Who says nothing interesting ever happens in the world anymore? This week, in a "first of its kind" operation, a brain-dead human subject was implanted with the world's first gene-edited pig liver transplant, according to SCMP. In…#scmp (Source: Reuters: Health)
Source: Reuters: Health - March 16, 2024 Category: Consumer Health News Source Type: news

Race, Ethnicity Plays Role in Liver Transplant Survival
THURSDAY, March 14, 2024 -- Researchers hope findings from a new study of liver transplant patients will lead to improved interventions for those from racial and ethnic minority groups. The study— led by researchers at UT Southwestern... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 14, 2024 Category: General Medicine Source Type: news

Jury awards $130m to Nevada residents who suffered extreme liver damage after drinking trendy bottled water that was laced with ROCKET FUEL chemical - killing one and prompting emergency transplant in another
The Clark County District Court jury awarded more than $30 million in compensatory damages to the plaintiffs including Myles Hunwardsen, who underwent a liver transplant at age 29. (Source: the Mail online | Health)
Source: the Mail online | Health - February 9, 2024 Category: Consumer Health News Source Type: news

Ultrasound'sticker' measures tissue stiffness
A wearable ultrasound sticker the size of a postage stamp can continuously measure tissue stiffness and may have a place in monitoring organ transplantation patients, according to research published February 9 in Science Advances. A team of researchers led by Hsiao-Chuan Liu, PhD, and doctoral students Yushun Zeng and Chen Gong of the University of Southern California found that their bio-adhesive ultrasound elastography (BAUS-E) sticker can continuously monitor the stiffness of organs over 48 hours and detect subtle changes that could signal the progression of disease such as organ failure and rejection. The group develo...
Source: AuntMinnie.com Headlines - February 9, 2024 Category: Radiology Authors: Amerigo Allegretto Tags: Ultrasound Source Type: news

Stigmatizing Language Common on Liver Transplant Websites
(MedPage Today) -- Stigmatizing words like "alcoholic" and "alcoholism" are frequently used on the websites of liver transplant centers, and this language may discourage patients from seeking treatment, according to a cross-sectional study. A... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 9, 2024 Category: Psychiatry Source Type: news

Study: Most U.S. liver transplant centers use alcohol-shaming language
Widespread online use of stigmatizing terms by liver transplant and rehab centers in the United States may be deterring patients from seeking treatment, according to a new study. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 8, 2024 Category: Consumer Health News Source Type: news

Severe hepatotoxicity in mushroom poisoning by Lepiota brunneoincarnata from complete recovery to liver transplantation: a case series with review on liver function tests and liver histopathology - Anbardar MH, Soleimani N, Kazemi K, Jafarpour Z, Hasani M, Mohammadzadeh S, Torfehnezhad P, Jafarian S, Farhadi M, Sardari MS.
BACKGROUND: In spite of the scientific evidence supporting health advantages of mushrooms, some of them are seriously poisonous. The clinical picture of mushroom intoxication ranges from minor gastrointestinal symptoms to organ failure, such as liver failu... (Source: SafetyLit)
Source: SafetyLit - February 1, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

[Ad hoc announcement pursuant to Art. 53 LR] Roche exceeds guidance and achieves sales growth of 1% (CER) for 2023 despite sharp COVID-19 sales decline
Group salesgrow by 1%1 at constant exchange rates (CER; -7% in CHF), more than offsetting the decline in COVID-19-related sales and biosimilar erosion, and thereby exceeding 2023 guidanceExcluding COVID-19 products,Group sales increase by 8%Pharmaceuticals Divisionsalesincrease by 6% (excluding COVID-19 medicine Ronapreve: +9%) due to ongoing high demand for newer medicines, with eye medicine Vabysmo continuing to be the top growth driver, followed by Ocrevus (multiple sclerosis), Hemlibra (haemophilia A) and Polivy (blood cancer)Diagnostics Division salesare 13% lower due to high demand for COVID-19 tests in 2022; strong ...
Source: Roche Media News - February 1, 2024 Category: Pharmaceuticals Source Type: news

[Ad hoc announcement pursuant to Art. 53 LR] Roche exceeds guidance and achieves sales growth of 1% (CER) for 2023 despite sharp COVID-19 sales decline
Group salesgrow by 1%1 at constant exchange rates (CER; -7% in CHF), more than offsetting the decline in COVID-19-related sales and biosimilar erosion, and thereby exceeding 2023 guidanceExcluding COVID-19 products,Group sales increase by 8%Pharmaceuticals Divisionsalesincrease by 6% (excluding COVID-19 medicine Ronapreve: +9%) due to ongoing high demand for newer medicines, with eye medicine Vabysmo continuing to be the top growth driver, followed by Ocrevus (multiple sclerosis), Hemlibra (haemophilia A) and Polivy (blood cancer)Diagnostics Division salesare 13% lower due to high demand for COVID-19 tests in 2022; strong ...
Source: Roche Investor Update - February 1, 2024 Category: Pharmaceuticals Source Type: news

1st-ever experiment shows how pigs might one day help help people with liver failure
In a potential bridge to transplant approach, U.S. surgeons successfully externally attached a pig liver to a brain-dead human body and watched it successfully filter blood. (Source: CBC | Health)
Source: CBC | Health - January 19, 2024 Category: Consumer Health News Tags: News/Health Source Type: news

1st-ever experiment shows how pigs might one day help people with liver failure
In a potential bridge to transplant approach, U.S. surgeons successfully externally attached a pig liver to a brain-dead human body and watched it successfully filter blood. (Source: CBC | Health)
Source: CBC | Health - January 19, 2024 Category: Consumer Health News Tags: News/Health Source Type: news

Experimental use of pig liver to filter blood externally offers hope for patients
Surgeons at University of Pennsylvania attached modified organ from pig to brain-dead human bodySurgeons externally attached a pig liver to a brain-dead human body and watched it successfully filter blood, a step toward eventually trying the technique in patients with liver failure.The University of Pennsylvania announced the novel experiment on Thursday, a different spin on animal-to-human organ transplants. In this case, the pig liver was used outside the donated body, not inside – a way to create a “bridge” to support failing livers by doing the organ’s blood-cleansing work externally, much like dialysis for fai...
Source: Guardian Unlimited Science - January 19, 2024 Category: Science Authors: Associated Press Tags: Medical research Science US news Source Type: news

How Pigs Could Help People Who Need Liver Transplants
In this study, eGenesis scientists used CRISPR to make not one, but 69 edits to the pig genome: three to remove the most pig-like proteins that would activate the human system to reject the liver, seven edits to add human genes to the pig liver, and 59 to inactivate pig retroviruses that could cause problems in humans. “Until CRISPR, there was no way to do that many edits easily,” says Curtis. The future of pig livers This single-patient study is just the beginning of what xenotransplants can achieve, says Shaked. The liver has two major duties in the body: regulating critical enzymes and substances such ...
Source: TIME: Health - January 18, 2024 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate Source Type: news

Roy Calne, Pioneering British Organ-Transplant Surgeon, Dies at 93
His innovations in the use of drugs to prevent organ rejection helped bring a remarkable increase in the one-year survival rate. (Source: NYT Health)
Source: NYT Health - January 15, 2024 Category: Consumer Health News Authors: Clay Risen Tags: Roy Calne Deaths (Obituaries) Surgery and Surgeons Transplants Liver Doctors Great Britain Thomas Starzl Source Type: news