Some hospitals wary as new liver transplant rules begin
A rule that will more broadly share donated livers goes into effect Tuesday. (Source: ABC News: Health)
Source: ABC News: Health - February 3, 2020 Category: Consumer Health News Tags: Health Source Type: news

Liver Transplant for Hepatocellular Carcinoma in the U.S. Liver Transplant for Hepatocellular Carcinoma in the U.S.
How have the patterns and outcomes for HCC-related liver transplants evolved over the last thirty years? A new study examines the trends.American Journal of Transplantation (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - February 3, 2020 Category: Surgery Tags: Transplantation Journal Article Source Type: news

Drug-induced liver injury caused by phenprobamate: strong probability due to repeated toxicity - Duzenli T, Tanoglu A, Akyol T, Kara M, Yazgan Y.
Drug-induced liver injury (DILI) is an important cause of morbidity and mortality. DILI can even cause acute liver failure and the need for liver transplantation. Identifying DILI may be particularly difficult because it is actually an exclusion diagnosis ... (Source: SafetyLit)
Source: SafetyLit - January 30, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Six patients with rare blood disease are doing well after gene therapy clinical trial
UCLA researchers are part of an international team that reported the use of a stem cell gene therapy to treat nine people with the rare, inherited blood disease known as X-linked chronic granulomatous disease, or X-CGD. Six of those patients are now in remission and have stopped other treatments. Before now, people with X-CGD – which causes recurrent infections, prolonged hospitalizations for treatment, and a shortened lifespan – had to rely on bone marrow donations for a chance at remission.“With this gene therapy, you can use a patient’s own stem cells instead of donor cells for a transplant,&rdqu...
Source: UCLA Newsroom: Health Sciences - January 28, 2020 Category: Universities & Medical Training Source Type: news

Elastography shows high reproducibility in breast lesions
Two different ultrasound elastography techniques -- strain elastography and...Read more on AuntMinnie.comRelated Reading: Mindray releases new ultrasound system Elastography helps liver transplant patients avoid biopsy Radiofrequency ultrasound, AI predict thyroid cancer Shear-wave elastography tracks effects of knee surgery Elastography methods reduce unnecessary breast biopsies (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 24, 2020 Category: Radiology Source Type: news

Dad loses 40 pounds so he can donate part of liver to son who needed life-saving transplant
Sean Kelley, from Rochester, New York, lost 40 pounds to donate part of his liver to his one-year-old son, Sawyer, who suffers from Alagille syndrome, which scars and damages the liver. (Source: the Mail online | Health)
Source: the Mail online | Health - January 20, 2020 Category: Consumer Health News Source Type: news

Federal judge allows new liver transplant policy to take effect
The nationwide plan will shift scarce organs from rural regions, where they are more plentiful, to cities where demand is highest. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - January 18, 2020 Category: Consumer Health News Authors: Lenny Bernstein Source Type: news

'Medical breakthrough' machine can keep a donated human liver alive for a WEEK
A group of scientists in Zurich, Switzerland, spent four years developing the Liver 4 Life machine which pumps blood in and out of a removed liver and keeps it warm and moving to preserve it for transplant. (Source: the Mail online | Health)
Source: the Mail online | Health - January 13, 2020 Category: Consumer Health News Source Type: news

Organ donation: new technique can preserve human livers for a week
Week-long storage boosts time organs are usable and distances over which they can be movedHuman livers from organ donors can now be preserved for a week, researchers have revealed, a dramatic improvement on previous techniques, which could only keep the organs usable for a matter of hours.The technology could boost the number of livers available for transplantation and offer new approaches to treating diseases such asliver cancer.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - January 13, 2020 Category: Science Authors: Nicola Davis Tags: Organ donation Medical research Health Society Science World news Source Type: news

' Excellent' Long-Term Outcomes for Recent Pediatric Liver-Transplant Recipients'Excellent' Long-Term Outcomes for Recent Pediatric Liver-Transplant Recipients
Liver transplant (LT) outcomes in children have improved substantially in the past three decades rendering earlier observed long-term outcomes irrelevant, researchers report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 10, 2020 Category: Consumer Health News Tags: Transplantation News Source Type: news

Clopidogrel Appropriate for PCI in Liver Transplant Candidates Clopidogrel Appropriate for PCI in Liver Transplant Candidates
In patients with decompensated cirrhosis undergoing percutaneous coronary intervention (PCI), clopidogrel safely inhibits platelet aggregation, according to a small study of liver-transplant candidates.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - January 8, 2020 Category: Surgery Tags: Cardiology News Source Type: news

Association of Autoimmune Hepatitis With Use of Biologicals Association of Autoimmune Hepatitis With Use of Biologicals
This study examined the incidence and prevalence of autoimmune hepatitis in a nationwide setting. Might its increasing incidence be due to more widespread use of biological drugs?Liver International (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - December 24, 2019 Category: Transplant Surgery Tags: Gastroenterology Journal Article Source Type: news

Mother, 35, risks her life to save her baby by undergoing dangerous transplant surgery
Danielle Roscoe, 35, saved her son Otis by donating part of her liver. Otis had biliary atresia and doctors in Leeds warned the baby boy would die without a transplant. (Source: the Mail online | Health)
Source: the Mail online | Health - December 24, 2019 Category: Consumer Health News Source Type: news

Researchers create functional mini-liver by 3D bioprinting
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Technique developed at Human Genome and Stem Cell Research Center, funded by FAPESP and hosted by the University of S ã o Paulo, produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 17, 2019 Category: Biology Source Type: news

Exercise Impact on Physical Frailty in Chronic Liver Disease Exercise Impact on Physical Frailty in Chronic Liver Disease
A new review examines the therapeutic benefits of exercise in chronic liver disease. Could it help improve frailty and quality of life among these patients?Alimentary Pharmacology & Therapeutics (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - December 11, 2019 Category: Transplant Surgery Tags: Gastroenterology Journal Article Source Type: news

Researchers create accurate model of organ scarring using stem cells in a lab
Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete.However, when healing is disrupted — whether by chronic injury or disease — the cells that make up scar tissue can go rogue, continuously dividing and spreading until the scar eventually strangles the organ it was intended to help heal, which can lead to organ failure.That progressive, out-of-control scarring is called fibrosis, and it can occur in any organ in the body. Fibrosis plays a major role in many dis...
Source: UCLA Newsroom: Health Sciences - December 11, 2019 Category: Universities & Medical Training Source Type: news

The next step in organ transplants: New startup takes aim at reperfusion injury
(Medical University of South Carolina) Lydex Pharmaceuticals, a startup founded by researchers at the Medical University of South Carolina and elsewhere, has received NIH funding to develop compounds for treating damage following ischemia reperfusion - the rapid reoxygenation that occurs when blood suddenly starts flowing again to a transplanted organ. By targeting histone deacetylases within the transplanted organ's cells, the group aims to prevent ischemia-reperfusion injury, a leading cause of liver failure after transplant or major liver surgery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 6, 2019 Category: International Medicine & Public Health Source Type: news

First investigational drug therapy for liver disease NASH awaiting FDA approval
Patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change. A large Phase III clinical trial designed in collaboration with Virginia Commonwealth University is the first to demonstrate the safety and effectiveness of an oral medication to treat the disease. (Source: World Pharma News)
Source: World Pharma News - December 5, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

First investigational drug therapy for liver disease NASH awaiting FDA approval
(Virginia Commonwealth University) Patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease and a leading cause for liver transplantation in the US, currently lack an approved drug therapy, but this may soon change. A large Phase III clinical trial designed in collaboration with Virginia Commonwealth University is the first to demonstrate the safety and effectiveness of an oral medication to treat the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 5, 2019 Category: International Medicine & Public Health Source Type: news

Policies Limit Medicaid Payment for Transplant in Alcoholic Liver Disease
FRIDAY, Nov. 22, 2019 -- Restrictive Medicaid policies are associated with a reduced proportion of payment by Medicaid for liver transplantation (LT) for alcohol-related liver disease (ALD) since 2011, according to a study published online Nov. 8 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 22, 2019 Category: Pharmaceuticals Source Type: news

MRI scoring system could predict liver transplant need
European researchers have developed a functional liver imaging score that uses...Read more on AuntMinnie.comRelated Reading: New MRI contrast material promises earlier liver diagnosis New PET tracer for liver shows preclinical promise Gadolinium dosing calculator can guide MRI contrast use (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 21, 2019 Category: Radiology Source Type: news

Tunisia: Two Successful Surgeries of Heart and Liver Transplant in Rabta and Mongi Slim Hospitals
[Tunis Afrique Presse] Tunis/Tunisia -Medical teams at the hospitals of Rabta in Tunis and Mongi Slim in Marsa, on Tuesday, successfully performed two surgeries of heart and liver transplant, said Director-General of the National Centre for the Promotion of Organ Transplantation (French: CNPTO) Taher Gargah. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 20, 2019 Category: African Health Source Type: news

The joy of seeing a life saved by the loss of my son
When the only hope for Lubna Siddiqui's critically-ill toddler, Fatima, was a liver transplant, Lisa Wilson's son, Tom, 22, saved her life through organ donation after he died. (Source: the Mail online | Health)
Source: the Mail online | Health - November 19, 2019 Category: Consumer Health News Source Type: news

High rates of vaccine-preventable infections in pediatric transplant patients
(University of Colorado Anschutz Medical Campus) University of Colorado researchers have found lower vaccination rates among children who receive liver transplants, increasing the risk of sickness for those children, who already face significant health issues. The findings are discussed in a 'Research Letter' included in the November 12, 2019 issue of JAMA and also call attention to data that CU School of Medicine faculty members published earlier this year in JAMA Pediatrics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 13, 2019 Category: International Medicine & Public Health Source Type: news

Pediatric Liver Transplant Recipients Often Undervaccinated
TUESDAY, Nov. 12, 2019 -- Many pediatric liver transplant recipients are undervaccinated, according to a research letter published in the Nov. 12 issue of the Journal of the American Medical Association. Amy G. Feldman, M.D., from the University of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 12, 2019 Category: Pharmaceuticals Source Type: news

University of Cincinnati finds new option for liver transplant patients
(University of Cincinnati) Budesonide, a drug commonly used to treat Crohn's Disease, may offer fewer side effects and work at least as well as prednisone as an anti-organ rejection medication in liver transplant patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 8, 2019 Category: International Medicine & Public Health Source Type: news

3D printing may improve safety of upper GI surgery
3D-printed models of the upper gastrointestinal (GI) tract provided several...Read more on AuntMinnie.comRelated Reading: 3D-printed head customizes neurosurgery simulation How can 3D printing improve kidney cancer surgery? 3D printing enhances chest wall reconstruction 3D printing cuts hip fracture repair time, blood loss 3D printing reduces liver transplant costs, surgery time (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 7, 2019 Category: Radiology Source Type: news

Study shows artificial intelligence can detect language problems tied to liver failure
(Johns Hopkins Medicine) Natural language processing, the technology that lets computers read, decipher, understand and make sense of human language, is the driving force behind internet search engines, email filters, digital assistants such as Amazon's Alexa and Apple's Siri, and language-to-language translation apps. Now, Johns Hopkins Medicine researchers say they have given this technology a new job as a clinical detective, diagnosing the early and subtle signs of language-associated cognitive impairments in patients with failing livers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 7, 2019 Category: International Medicine & Public Health Source Type: news

Three UCLA scientists receive grants totaling more than $18 million
Three researchers at the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards totaling more than $18 million from the California Institute for Regenerative Medicine, the state’s stem cell agency. The recipients areDr. Sophie Deng, professor of ophthalmology at the UCLA Stein Eye Institute;  Yvonne Chen, a UCLA associate professor of microbiology, immunology and molecular genetics; andDr. Caroline Kuo, a UCLA assistant clinical professor of pediatrics. The awards were announced at a CIRM meeting today.Deng ’s four-year, $10.3 million award ...
Source: UCLA Newsroom: Health Sciences - October 31, 2019 Category: Universities & Medical Training Source Type: news

Contrast US biomarkers predict cancer in liver nodules
Biomarkers derived from contrast-enhanced ultrasound scans -- such as differences...Read more on AuntMinnie.comRelated Reading: Contrast ultrasound is effective for liver, kidney lesions Artificial intelligence may help bridge experience gap for liver CEUS ARRS: Contrast ultrasound works well for liver lesions CEUS characterizes incidental liver lesions on CT, MRI Contrast US processing tool shows malignant liver lesions (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 28, 2019 Category: Radiology Source Type: news

He ’s the First African American to Receive a Face Transplant. His Story Could Change Health Care
Robert Chelsea turned down the first face he was offered. It was a fine face, one that could have taken him off the transplant waiting list after just a couple months. But Chelsea—severely disfigured after a catastrophic car accident five years earlier—was in no hurry. He’d gotten used to tilting his head back so food and water wouldn’t fall out of his nearly lipless mouth. He knew how to respond compassionately to children who stared in shock and fear. The face, offered in May 2018, had belonged to a man with skin that was much fairer than what remained of Chelsea’s—so light that Chelse...
Source: TIME: Health - October 24, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Healthcare Source Type: news

Novartis shells out $80M for Peninsula company's preclinical liver drug
Thanks in part to a six-person go-team testing fresh liver tissue from transplant patients at UCSF and Stanford, this young South San Francisco company has a "validating" deal. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - October 23, 2019 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

New Method Supports Sustained Perfusion of Transplanted Bioengineered Livers New Method Supports Sustained Perfusion of Transplanted Bioengineered Livers
A new optimized method for revascularizing bioengineered livers provides up to 15 days of continuous perfusion after transplantation into immunosuppressed pigs.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - October 20, 2019 Category: Pathology Tags: Transplantation News Source Type: news

Top 34 Bestselling ‘ Fruit ’ Drinks For Kids Deemed Unhealthy
(CNN) — Americans spent $1.4 billion on the most popular brands of children’s fruit drinks and flavored waters last year. Yet according to nutritional guidelines, none of the drinks were healthy. Why would loving parents do this? Perhaps because US beverage companies spent $20.7 million to advertise fun, fruity drinks with added sugars to families in 2018, according to Children’s Drink Facts 2019, a new report from the University of Connecticut’s Rudd Center for Food Policy and Obesity. “I know that parents want their children to be healthy, but the sweetened drink market is just incredibly co...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 16, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN juice Source Type: news

Infographic: MELD scores for liver transplants
Learn more about liver transplants. Other health tip infographics:?mayoclinichealthhighlights.startribune.com (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 16, 2019 Category: Databases & Libraries Source Type: news

Behavioral Interventions for Alcohol-Related Liver Disease Behavioral Interventions for Alcohol-Related Liver Disease
Could behavioral treatments help prevent alcohol relapse among liver transplant candidates and recipients with alcohol-related liver disease?American Journal of Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 15, 2019 Category: Consumer Health News Tags: Transplantation Journal Article Source Type: news

In the Loop: Get me to the church on time
Just three weeks after a combined liver and kidney transplant at Mayo Clinic in Florida, Chris Nutter was able to fly to New York to surprise his daughter and walk her down the aisle. Chris Nutter thought the jig was up. That all the preparation he and his care team at Mayo Clinic had put into surprising [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 15, 2019 Category: Databases & Libraries Source Type: news

A Blood Filter Fights Deadly Inflammatory Response
A new blood filtration technology may prove to be life-saving for patients whose normally healthy inflammatory response to injury or illness has gone into overdrive, resulting in fatally high levels of cytokines in their blood. In an interview with MD+DI, Dr. Phillip Chan, MD, PhD, CEO of CytoSorbents Corp., explained that inflammation, and the production of substances called cytokines that drive inflammation, are the body’s natural response to heal injury or infection. But sometimes, the inflammatory response is so severe in such conditions as sepsis and infection, burn injuries, trauma, pancreatitis, li...
Source: MDDI - October 9, 2019 Category: Medical Devices Authors: Susan Shepard Tags: Cardiovascular Source Type: news

Elastography helps liver transplant patients avoid biopsy
Ultrasound with a shear-wave elastography technique can help liver transplant...Read more on AuntMinnie.comRelated Reading: Shear-wave elastography tracks effects of knee surgery SWE identifies malignant breast microcalcifications SWE improves plantar fasciitis diagnosis Shear-wave elastography useful for assessing rectal tumor depth Shear-wave elastography helps diagnose Graves' disease (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 8, 2019 Category: Radiology Source Type: news

IBM Watson and Guerbet Want to Tackle Prostate Cancer Diagnosis with AI
Guerbet has landed a second co-development agreement with IBM Watson Health. This time around, the two companies will develop an artificial intelligence tool to help clinicians detect, segment, characterize, and monitor prostate cancer. “The main diagnostic challenge with prostate cancer lies in identifying cancers requiring rapid treatment and those requiring only active surveillance while avoiding unnecessary biopsies," said David Gruen, MD, chief medical officer of imaging at IBM Watson Health. “For this reason, optimal patient outcomes depend ...
Source: MDDI - September 23, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

Liver Transplants Rarely Performed for Unauthorized Immigrants
FRIDAY, Sept. 20, 2019 -- Liver transplantation (LT) is rarely performed for unauthorized immigrants in the United States, according to a study published online Sept. 20 in Hepatology. Brian P. Lee, M.D., from the University of California in San... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 20, 2019 Category: Pharmaceuticals Source Type: news

Can AI screen for nonalcoholic fatty liver disease?
An artificial intelligence (AI) algorithm was able to automatically quantify...Read more on AuntMinnie.comRelated Reading: Ultrasound useful for evaluating liver steatosis MRI offers view of liver fat loss in obese patients Ultrasound options abound for diagnosing liver disease AIUM: Can deep learning classify liver fibrosis on US? Fatty liver disease occurs with risky plaque (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 20, 2019 Category: Radiology Source Type: news

Sepsis in patients with cirrhosis awaiting liver transplantation: new trends and management
Bacterial infections are more frequent and severe in patients with advanced liver disease and, therefore, in liver transplant candidates. The increased risk of infection in these patients parallels the severity of the immune dysfunction associated with cirrhosis, featured by systemic inflammation and progressive immunodeficiency. Other factors contribute to this risk, such as genetic polymorphisms, proton-pump inhibitor overuse, the numerous invasive procedures and hospitalizations these patients go through, or the immunosuppressive effects of malnutrition or alcohol abuse. Bacterial infections have a great impact on disea...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Frailty Assessment May Aid Liver Transplant Evaluation
THURSDAY, Sept. 19, 2019 -- A frailty assessment as part of liver transplant evaluation may help identify transplant candidates at higher risk for death, according to a study published online Sept. 11 in JAMA Surgery. Christine E. Haugen, M.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 19, 2019 Category: Pharmaceuticals Source Type: news

Seeking an Obesity Cure, Researchers Turn to the Gut Microbiome
The link between the gut and metabolic disease is a growing area of obesity research. (Source: NYT Health)
Source: NYT Health - September 10, 2019 Category: Consumer Health News Authors: Anahad O ’Connor Tags: Obesity Feces Digestive Tract Transplants Liver Weight Bacteria Infections Source Type: news

A 'Supercool' Breakthrough for Patients Awaiting Liver Transplant
Title: A 'Supercool' Breakthrough for Patients Awaiting Liver TransplantCategory: Health NewsCreated: 9/9/2019 12:00:00 AMLast Editorial Review: 9/10/2019 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - September 10, 2019 Category: Nutrition Source Type: news

Scientists TRIPLE the time human livers can be stored for to 27 hours
There are currently 431 people waiting for a liver transplant in the UK and last year 45 died while on the waiting list. The new breakthrough was made by experts at Harvard Medical School. (Source: the Mail online | Health)
Source: the Mail online | Health - September 9, 2019 Category: Consumer Health News Source Type: news

Scientists triple storage time of human donor livers
NIH-funded research project develops new method to preserve human livers for transplantation. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 9, 2019 Category: American Health Source Type: news

A'Supercool' Breakthrough for Patients Awaiting Liver Transplant
MONDAY, Sept. 9, 2019 -- A new " supercooling " technique can triple the length of time a donor liver can be preserved before transplantation, researchers say. The new method -- which cools the liver to 21.2 degrees Fahrenheit without freezing it --... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 9, 2019 Category: General Medicine Source Type: news

A strong sibling bond grows closer with live organ transplant
In ultimate gift of sacrifice and selfless love, cable news journalist gives part of his liver to his ailing sister. What’s more, the organ grew back. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - August 31, 2019 Category: Consumer Health News Authors: Cathy Free Source Type: news