Extremity risk factors of sepsis for gastrointestinal endoscopy in patients with liver cirrhosis.
Background: Liver cirrhosis is a well-known risk factor of sepsis after emergent gastrointestinal (GI) endoscopy. Elective GI endoscopy before living donor liver transplantation (LDLT), however, may also carry the septic risk among these patients.
Methods: This retrospective study reviewed the medical records of 642 cirrhotic recipients who underwent GI endoscopy from 2008 to 2016. We analyzed the incidence and risk factors of post-endoscopy sepsis during 2008-2012 (experience cohort). Our protocol changed after 2013 (validation cohort) to include antibiotic prophylaxis.
Results: In experience cohort, 36 cases (10.5%) of...
Source: Current Awareness Service for Health (CASH) - March 2, 2022 Category: Consumer Health News Source Type: news
These Classes Are Near-Death Experiences, and That ’s a Good Thing
Spirits are high as the students file into the basement of the Galante Funeral Home in Union, N.J., to pick out their caskets.
Jessica Polynice, 23, beelines toward the most ornate one in the showroom, joking that she has expensive taste. Others consider the prominently displayed price tags, from $995 to nearly $6,000, and factor in the softness of the pillows. Surrounded by open caskets, Amanda Davis, 20, says she’d rather be cremated into a firework. Beside her, Lauren Duffy, 24, flips through a brochure for artificial reef cremations and weighs whether she’d like to be eternally memorialized on the ocean flo...
Source: TIME: Health - February 23, 2022 Category: Consumer Health News Authors: Melissa Chan Tags: Uncategorized COVID-19 feature nationpod Source Type: news
Role of Gut Microbiota in HBV Disease Progression and Treatment Role of Gut Microbiota in HBV Disease Progression and Treatment
This review aims to clarify our understanding of the pathophysiology of gut microbiota and their relationship with liver injury in chronic hepatitis B. How might this inform future therapeutics?Journal of Viral Hepatitis (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - February 21, 2022 Category: Transplant Surgery Tags: Gastroenterology Journal Article Source Type: news
Robotic Donor Hepatectomy: A Major Breakthrough in LDLT Robotic Donor Hepatectomy: A Major Breakthrough in LDLT
Learn more about this breakthrough technology and how it could benefit living donor liver transplantation.American Journal of Transplantation (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - January 20, 2022 Category: Transplant Surgery Tags: Transplantation Journal Article Source Type: news
Good Long-Term Outcomes of Kidney/Liver Transplant in Adults With HIV Good Long-Term Outcomes of Kidney/Liver Transplant in Adults With HIV
HIV-positive kidney- and liver-transplant patients can expect good long-term outcomes following the transplant, comparable with those of matched HIV-negative peers, according to a new study.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - January 18, 2022 Category: Gastroenterology Tags: Transplantation News Source Type: news
Machine Perfusion Boosts Outcomes of Liver Transplant Machine Perfusion Boosts Outcomes of Liver Transplant
When preparing deceased-donor livers for transplant, portable normothermic blood-based machine perfusion improves transplant outcomes than ischemic cold storage, according to results of the PROTECT trial.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - January 6, 2022 Category: Transplant Surgery Tags: Transplantation News Source Type: news
The future is bright for RWE in pharma approvals
Real-world evidence (RWE) could help pharma achieve many things – including understanding disease burden better and smarter monitoring of newly marketed therapies to make them safer and more effective. But the most promising near-term use case for RWE, according to a Deloitte survey of pharma executives, is in support of regulatory submissions and label expans ion. For industry stakeholders such as Marc Berger, M.D., this advance is a long time coming. The founder of the real-world data (RWD) and analytics group at Pfizer, Berger has been a contributing author on dozens of policy papers on the use of RWE – including ...
Source: EyeForPharma - January 6, 2022 Category: Pharmaceuticals Authors: Brian Eastwood Source Type: news
HIV+ Patients Get Good Outcomes After Kidney or Liver Transplant HIV+ Patients Get Good Outcomes After Kidney or Liver Transplant
Patient and graft survival outcomes after 15 years support transplant benefits in HIV population.Medscape Medical News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - January 5, 2022 Category: Transplant Surgery Tags: HIV/AIDS News Source Type: news
Outcome of plasma exchange in acute liver failure due to yellow phosphorus poisoning: a single-center experience - Angraje S, Sekar M, Mishra B, Matcha J.
BACKGROUND: Yellow phosphorus (YP) is a protoplasmic poison that causes acute liver failure (ALF) for which liver transplantation is the definitive modality. Hereby, we present our clinical data on the role of plasma exchange (PE) in ALF due to YP poisonin... (Source: SafetyLit)
Source: SafetyLit - December 31, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Lawsuit alleges bullying tactics by transplant executives in bid to revamp system
Plaintiffs in a two-year-old lawsuit say emails show executives worked behind the scenes on a policy that would take more human livers from rural areas and send them to big-city transplant centers. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - December 22, 2021 Category: Consumer Health News Authors: Lenny Bernstein Source Type: news
FDA Approves Two New Indications for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, Dec. 20, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved two pediatric indications for XARELTO® (rivaroxaban): the treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients from birth to less than 18 years after at least five days of initial parenteral (injected or intravenous) anticoagulant treatment; and thromboprophylaxis (prevention of blood clots and blood-clot related events) in children aged two years and older with congenital heart disease who have...
Source: Johnson and Johnson - December 21, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Virtual Center Boosts Liver Transplant Listings in Rural Area Virtual Center Boosts Liver Transplant Listings in Rural Area
By tackling pretransplant screening, a medical center in New Hampshire expedited listing for rural residents.Medscape Medical News (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - December 6, 2021 Category: Surgery Tags: Gastroenterology News Source Type: news
Neonatal Cholestasis: Updates on Diagnostics, Therapeutics, and Prevention
Cholestatic jaundice is a common presenting feature of hepatobiliary and/or metabolic dysfunction in the newborn and young infant. Timely detection of cholestasis, followed by rapid step-wise evaluation to determine the etiology, is crucial to identify those causes that are amenable to medical or surgical intervention and to optimize outcomes for all infants. In the past 2 decades, genetic etiologies have been elucidated for many cholestatic diseases, and next-generation sequencing, whole-exome sequencing, and whole-genome sequencing now allow for relatively rapid and cost-effective diagnosis of conditions not previously i...
Source: NeoReviews recent issues - December 1, 2021 Category: Pediatrics Source Type: news
UK biotech raises $156m to develop immune system engineering
Quell to start clinical trials of product designed to prevent rejection of liver transplants (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - November 29, 2021 Category: Pharmaceuticals Source Type: news
Demand for Liver Transplant Rises Sharply Among Older Americans
Title: Demand for Liver Transplant Rises Sharply Among Older AmericansCategory: Health NewsCreated: 11/17/2021 12:00:00 AMLast Editorial Review: 11/17/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - November 17, 2021 Category: Nutrition Source Type: news
