Association Between the Fatty Liver Index and CKD Association Between the Fatty Liver Index and CKD
Data from the KORA study provides insight into the potential association between the fatty liver index and the incidence of CKD.Nephrology Dialysis Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 13, 2023 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

HRQoL in Patients With Primary Sclerosing Cholangitis HRQoL in Patients With Primary Sclerosing Cholangitis
A survey of patients with primary sclerosing cholangitis provides a better understanding of the factors associated with health-related quality of life.Liver International (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - June 9, 2023 Category: Transplant Surgery Tags: Gastroenterology Journal Article Source Type: news

Can ‘toxic’ bilirubin treat a variety of illnesses?
Generations of medical and biology students have been instilled with a dim view of bilirubin. Spawned when the body trashes old red blood cells, the molecule is harmful refuse and a sign of illness. High blood levels cause jaundice, which turns the eyes and skin yellow and can signal liver trouble. Newborns can’t process the compound, and although high levels normally subside, a persistent surplus can cause brain damage. Yet later this year up to 40 healthy Australian volunteers may begin receiving infusions of the supposedly good-for-nothing molecule. They will be participating in a phase 1 safety trial, sponsored...
Source: ScienceNOW - June 8, 2023 Category: Science Source Type: news

NASH Drug Shown to Reduce Liver Fat by 65% in Some Patients NASH Drug Shown to Reduce Liver Fat by 65% in Some Patients
Akero Therapeutics said on Monday data from a mid-stage study showed its experimental therapy reduced liver fat by 65% in certain patients with a type of fatty liver disease called nonalcoholic steatohepatitis.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - June 7, 2023 Category: Transplant Surgery Tags: Gastroenterology News Source Type: news

Barclay urged to act by Lib-Dem rival after failing to respond to patient's plea
EXCLUSIVE: Gravely ill Sarah Meredith in two-year wait for a liver transplant. (Source: Daily Express - Health)
Source: Daily Express - Health - June 5, 2023 Category: Consumer Health News Source Type: news

Janssen to Highlight Scientific Advances and Commitment to Transform Cancer Care at ASCO and EHA with More than 90 Presentations Showcasing Robust, Differentiated Portfolio and Pipeline in Hematologic Malignancies and Solid Tumors
This study evaluates an investigational combination regimen of IMBRUVICA® (ibrutinib) plus venetoclax (I+V) for newly diagnosed chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), (Abstracts #7535 and #P617, respectively).Advancing the Science of Solid Tumors Through Precision MedicineJanssen’s continued innovation in solid tumors focuses on advancing precision medicine options for patients with biomarker-driven disease who have limited targeted treatment options and moving patients into earlier lines of therapy when treatments may be more effective. Lung CancerAn oral presentation will report ...
Source: Johnson and Johnson - May 18, 2023 Category: Pharmaceuticals Tags: Innovation Source Type: news

Role of therapeutic plasma exchange in rat killer (yellow phosphorous) poisoning - Radhakrishnan K, Thokala RP, Anandan A, Rengan CS.
CONTEXT: Yellow phosphorus (YP) 3% is one of the rodenticides available, which is a potent hepatotoxin and it is fatal. Management of YP poisoning is difficult since there is no antidote available; only definitive management is liver transplantation. Thera... (Source: SafetyLit)
Source: SafetyLit - May 18, 2023 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Viking Therapeutics's NASH Drug Succeeds in Midstage Trial Viking Therapeutics's NASH Drug Succeeds in Midstage Trial
Viking Therapeutics said on Tuesday its experimental drug met the main goal of a mid-stage trial to treat patients with a type of fatty liver disease, sending its shares about 6% higher in early trade.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - May 17, 2023 Category: Transplant Surgery Tags: Gastroenterology News Source Type: news

When does life end? New organ donation strategy fuels debate
On a chilly holiday Monday in January 2020, a medical milestone passed largely unnoticed. In a New York City operating room, surgeons gently removed the heart from a 43-year-old man who had died and shuttled it steps away to a patient in desperate need of a new one. More than 3500 people in the United States receive a new heart each year. But this case was different—the first of its kind in the country. “It took us 6 months to prepare,” says Nader Moazami, surgical head of heart transplantation at New York University (NYU) Langone Health, where the operation took place. The run-up included oversight from an eth...
Source: ScienceNOW - May 11, 2023 Category: Science Source Type: news

Potential Benefit of Corticosteroids in DILI Potential Benefit of Corticosteroids in DILI
The administration of corticosteroids to treat severe drug-induced liver injury remains controversial, but this analysis revealed no serious adverse effects and improved outcomes.Alimentary Pharmacology & Therapeutics (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - April 27, 2023 Category: Transplant Surgery Tags: Gastroenterology Journal Article Source Type: news

The silent liver disease experts warn is on the rise among Hispanics and children
Two months after his liver transplant, Juan Silva with his wife, Gisela Juan and Gisela Silva have a lot to smile about these days. One reason why, they are back to enjoying home-cooked together. "Oh man, I can eat more now," says Juan. "Before I didn't want to eat anything because it would mess up my stomach and stuff because something wasn't working right." That led Juan to his doctor's office where a series of… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 26, 2023 Category: Databases & Libraries Source Type: news

Transplant Chief Was an Organ Recipient Herself
(MedPage Today) -- Though it wasn't so long ago that Sara Kathryn Smith, MD, was a liver transplant patient herself, last year she became the medical director for pediatric liver transplantation at Johns Hopkins Children's Center in Baltimore... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 20, 2023 Category: Gastroenterology Source Type: news

Late-Onset Rejection in Liver Allograft Biopsies Late-Onset Rejection in Liver Allograft Biopsies
This study examines the clinicopathologic features and histopathologic spectrum of late-onset rejections in liver allograft recipients.American Journal of Clinical Pathology (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - April 19, 2023 Category: Transplant Surgery Tags: Pathology & Lab Medicine Journal Article Source Type: news

Harnessing ChatGPT to Improve Liver Disease Outcomes Harnessing ChatGPT to Improve Liver Disease Outcomes
ChatGPT may be a useful adjunctive informational tool for patients with cirrhosis or liver cancer and their clinicians by generating easy-to-understand information about the disease.Medscape Medical News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - April 13, 2023 Category: Transplant Surgery Tags: Gastroenterology News Source Type: news

Liver Transplants for CRC Metastases: Coming Into Its Own? Liver Transplants for CRC Metastases: Coming Into Its Own?
Although still controversial, transplantation is gaining traction as a treatment option for patients with colorectal liver metastases and intrahepatic cholangiocarcinoma.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 11, 2023 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news