The tuberculosis pathogen releases its toxin by a novel protein transport system
(University of Alabama at Birmingham) Six years ago, Michael Niederweis, Ph.D., described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis. However, the mechanism for its secretion from the bacterium was unknown. Now, researchers describe two small Esx proteins that form pores in bacterial membranes and are essential for toxin release. This transport system may be widespread across many Gram-positive bacteria that contain proteins in the WXG100 superfamily. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 8, 2021 Category: Infectious Diseases Source Type: news

New study explains Mycobacterium tuberculosis high resistance to drugs and immunity
(Skolkovo Institute of Science and Technology (Skoltech)) A consortium of researchers from Russia, Belarus, Japan, Germany, and France led by a Skoltech scientist have uncovered the way in which Mycobacterium tuberculosis survives in iron-deficient conditions by utilizing rubredoxin B, a protein from a rubredoxin family that play an important role in adaptation to changing environmental conditions. The new study is part of an effort to study the role of M. tuberculosis enzymes in developing resistance to the human immune system and medication. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 8, 2021 Category: Infectious Diseases Source Type: news

South Africa: SA Piloting Mobile X-Rays to Improve TB Detection
[spotlight] One of the most striking findings of South Africa's first National Tuberculosis (TB) Prevalence Survey was that of 234 people found to have TB, around 58% had abnormal chest X-rays without experiencing any TB symptoms. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - April 7, 2021 Category: Infectious Diseases Source Type: news

Daily chest x-rays not needed in COVID-19 patients
Chest x-rays are effective every three or four days rather than daily for monitorin...Read more on AuntMinnie.comRelated Reading: WHO recommends CAD with chest x-rays to fight tuberculosis CXR-Age algorithm assesses biological age on chest radiographs Curbing daily use of chest x-ray in ICU cuts major costs Consider COVID-19 chest imaging patterns to prep for next pandemic MIDRC releases first set of COVID-19 images (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 1, 2021 Category: Radiology Source Type: news

Bile and Potatoes, 1921
One hundred years after its invention, BCG has stood the test of time as a vaccine against tuberculosis. (Source: The Scientist)
Source: The Scientist - April 1, 2021 Category: Science Tags: Foundations Magazine Issue Source Type: news

Tuberculosis Cases Largely Declined Across United States in 2020
WEDNESDAY, March 31, 2021 -- In 2020, there was a large decrease in tuberculosis (TB) cases, according to research published in the March 26 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Molly... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 31, 2021 Category: Pharmaceuticals Source Type: news

Ghana: Make Conscious Efforts to Handle Discrimination Against TB Patients and Caregivers
[Ghanaian Times] The Ghana Health Service (GHS) has directed all health facilities in the country to include tuberculosis (TB) in their screening for COVID-19, as both present similar symptoms like coughing, difficulty in breathing and fever. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 29, 2021 Category: Infectious Diseases Source Type: news

Nigeria: New 51 Cases of Tuberculosis Discovered in Benue
[This Day] Makurdi -- Fifty One new cases of tuberculosis (TB) have been discovered in Benue State from a test conducted on 609 samples screened for the contagious disease. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 29, 2021 Category: Infectious Diseases Source Type: news

The role of benzothiazole analogs in the treatment of tuberculosis
(Bentham Science Publishers) This book will help to get the glimpse on tuberculosis disease and the wide information to carry out further research on benzothiazole as an anti-TB drug. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 29, 2021 Category: Biology Source Type: news

Rwanda: Covid-19 Outbreak Dented Efforts to Fight Tuberculosis, Medics Say
[New Times] Medical workers have rallied policymakers to support efforts aimed at increasing the detection and treatment of Tuberculosis (TB), saying there has been a setback in the fight against the disease following the outbreak of Covid-19. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 26, 2021 Category: Infectious Diseases Source Type: news

South Africa: SA At Cutting Edge of TB Vaccine Research
[spotlight] It is a hundred years since the BCG (Bacille Calmette-Guerin) vaccine, the only registered vaccine proven to offer some protection against tuberculosis , was first used in people. A relative shortage of public funding and little interest from pharmaceutical companies to develop new unprofitable TB vaccines has frustrated scientific research in this area for most of the last century. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 26, 2021 Category: African Health Source Type: news

Kenya: Alarm Raised Over Rising TB Infections in Turkana County
[Nation] Authorities in Turkana County have raised the alarm over a spike in tuberculosis (TB) infections in the recent months. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 26, 2021 Category: Infectious Diseases Source Type: news

Ethiopia: 'It Is the Time to End TB'
[Ethiopian Herald] Every year, global communities mark World Tuberculosis (TB) Day with the aim to raise public awareness about the devastating health, social and economic impacts of the disease, strengthen effective intervention and at the same time, step up efforts to end the global TB epidemic. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 26, 2021 Category: Infectious Diseases Source Type: news

Botswana: Botswana Needs to Accelerate TB Response
[Botswana Daily News] Gaborone -- The world and its leaders have only a year left to achieve the United Nations Political Declaration on Tuberculosis (TB) commitments. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 26, 2021 Category: Infectious Diseases Source Type: news

Uganda: USAID Injects Shs27b in TB Programme
[Monitor] United States Agency for International Development (USAID) has injected $7.5m (about Shs27.4b) in Karamoja Sub-region to address high tuberculosis (TB) prevalence and low treatment success rates in the area. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 26, 2021 Category: Infectious Diseases Source Type: news

Thirona launches AI algorithm for cystic fibrosis
Software developer Thirona is launching Pragma-AI, a new artificial intelligenc...Read more on AuntMinnie.comRelated Reading: Thirona licenses patent for cystic fibrosis AI software Meet the Minnies 2020 semifinal candidates Thirona, Smart Reporting team up on COVID-19 software Thirona unveils AI software for COVID-19 analysis AI-based CAD accurately detects tuberculosis on chest x-rays (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 25, 2021 Category: Radiology Source Type: news

Median Health Care Delay 24 Days for TB Patients in United States
THURSDAY, March 25, 2021 -- The median health care delay for patients with tuberculosis (TB) in the United States is 24 days, according to a study published online March 23 in The Lancet Infectious Diseases. Jessica El Halabi, M.D., from Harvard... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 25, 2021 Category: Pharmaceuticals Source Type: news

Epidemiology of Tuberculosis and Progress Toward Meeting Global Targets - Worldwide, 2019
This report describes current progress toward achieving global targets for reducing tuberculosis incidence. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - March 25, 2021 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Source Type: news

Tuberculosis - United States, 2020
This report describes changes in tuberculosis incidence in the United States. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - March 25, 2021 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Source Type: news

When Dogma And Politics Trump Science
The basis for the “science” of 6 feet of distance is rooted in work done with tuberculosis in the late 19th century, not on current scientific inquiry. Presenting it as a “fact” that applies to a current situation has been greatly misleading. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 25, 2021 Category: Pharmaceuticals Authors: Rita Numerof, Contributor Tags: Healthcare /healthcare Innovation /innovation Source Type: news

Mozambique: Govt Commits to Controlling Tuberculosis
[AIM] Maputo -- Mozambican Prime Minister Carlos Agostinho do Rosario has reaffirmed the government's commitment to adopt effective strategies to fight tuberculosis. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

South Africa: Western Cape Government Commemorates World TB Day 2021
[Govt of SA] Western Cape Government and partners developing emergency response to TB; R80 million in donor funding secured (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

Challenges and opportunities to end tuberculosis in the COVID-19 era, The Lancet Respiratory Medicine
Article highlights COVID-19 has challenged health systems and restricted essential health service delivery for tuberculosis in many countries. To avoid further morbidity and mortality, strategies are urgently required to mitigate the impact of COVID-19 on tuberculosis. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 25, 2021 Category: Consumer Health News Source Type: news

Collaborative TB Strategy for England, 2015 to 2020 End of programme report
This report highlights the outcomes of this collaborative strategy, which was created in response to the high rates of tuberculosis in England. It also makes recommendations for future work in order to achieve a 90% reduction in tuberculosis incidence by 2035. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 25, 2021 Category: Consumer Health News Source Type: news

Africa: World Tuberculosis Day
[State Department] Today, on World Tuberculosis Day, the global community acknowledges the progress made and the challenges that lie ahead in fighting tuberculosis (TB). While COVID-19 has had a devastating global impact over the past year, TB has long been the world's leading infectious disease killer and continues to kill more people in low-and middle-income countries than any other infectious disease. Despite being preventable and curable, TB sickens 10 million people and takes 1.4 million lives, year after year. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 25, 2021 Category: African Health Source Type: news

Africa: TB Testing in 2020 Dropped Drastically Due to Covid-19
[The Global Fund] On World Tuberculosis Day, new data shows the COVID-19 pandemic has had a devastating impact on the fight against another deadly airborne disease: tuberculosis. Global Fund surveys in 13 countries with the highest TB burden in the world reveal that 29% fewer people were tested for TB compared to 2019. Worse, in those same countries, there were 45% fewer people tested for multidrug-resistant TB -- one of the most frightening forms of antimicrobial resistance. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 25, 2021 Category: African Health Source Type: news

Botswana: Intensify TB Fighting Efforts - Dikoloti
[Botswana Daily News] Gaborone -- As Botswana joined the world in commemorating World Tuberculosis (TB) Day yesterday, Minister of Health and Wellness, Dr Edwin Dikoloti underscored the need for intensification of efforts to find missing undiagnosed TB cases. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 25, 2021 Category: African Health Source Type: news

Nigeria: Nigeria Still Far From Achieving 2022 Target On TB Control - WHO
[This Day] World Health Organisation (WHO) has expressed worry that the country may not be able to reach its set target of diagnosing and treating over 1.1 million TB cases by next year. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

Nigeria: Governors Seek Measures to Combat Tuberculosis Spike
[This Day] Governors yesterday called for urgent steps to arrest the rising cases of tuberculosis in Nigeria. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

Nigeria: World TB Day - HIV, Smoking Main Drivers of TB Burden in Nigeria - Govt
[Daily Trust] The federal government has identified under-nutrition, HIV, diabetes, smoking and alcohol use as the main drivers of the tuberculosis burden in Nigeria. (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - March 25, 2021 Category: Infectious Diseases Source Type: news

Africa: WHO Announces Updated Guidance On the Systematic Screening for Tuberculosis
[WHO] New guidelines released by the World Health Organization(WHO) update several recommendations on the systematic screening of tuberculosis(TB) disease. This will help national TB programmes, public and private healthcare providers, funders and other stakeholders improve actions to detect TB earlier and close gaps in prevention and care. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

Africa: WHO Director-General's Opening Remarks At the Media Briefing On Covid-19 - 22 March 2021
[WHO] This Wednesday is World TB Day. An estimated 1.4 million fewer people received care for TB in 2020 compared with 2019, and we fear that more than half a million more people may have died. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

Nigeria: Tuberculosis Kills 162,000 Nigerians Annually - NTS
[Leadership] The Nigerian Thoracic Society (NTS) has revealed that over 162,000 persons die of tuberculosis in the country annually. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

Nigeria: World Tuberculosis Day - Health Experts Call for More Awareness
[Premium Times] "More awareness like this is needed for them to know the signs and symptoms associated with tuberculosis." (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

Nigeria: World Tuberculosis Day - Eight Ways to Prevent Spread of TB
[Premium Times] When people with tuberculosis cough, sneeze or spit, they propel the TB germs into the air. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 25, 2021 Category: Infectious Diseases Source Type: news

WHO recommends CAD with chest x-rays to fight tuberculosis
The World Health Organization (WHO) has updated its recommendations for tuberculosi...Read more on AuntMinnie.comRelated Reading: AI-based CAD accurately detects tuberculosis on chest x-rays Are studies on AI for tuberculosis really valid? FDG-PET/CT helps predict tuberculosis relapse PET shows efficacy of tuberculosis meningitis drug Portable automated x-ray system targets tuberculosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 24, 2021 Category: Radiology Source Type: news

South Africa: Men Urged to Test for TB
[SAnews.gov.za] Deputy President David Mabuza has called on South African men to be counted in the nation's efforts to end tuberculosis (TB) by getting tested. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 24, 2021 Category: African Health Source Type: news

Africa: 1.4 Million People With TB Lost Out On Treatment During First Year Of Covid-19
[UN News] An estimated 1.4 million fewer people received necessary care for tuberculosis (TB) during 2020 compared with the previous year, because of COVID-19, the UN health agency  said on Monday. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

Nigeria: The Tuberculosis Scourge
[This Day] The health authorities could do more to stem the menace (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

Africa: Drug-Resistant Tuberculosis Trial Ends Enrolment After Positive Initial Data
[MSF] London - A trial aiming to find a better treatment for multidrug-resistant tuberculosis (MDR-TB) has stopped enrolling patients early after its independent data safety and monitoring board indicated that the regimen being studied is superior to current care, and more patient data was extremely unlikely to change the trial's outcome. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

South Africa: WORLD TB DAY: Addressing the Ocean of Gaps in the Treatment of TB in Children and Adolescents
[MSF] Moving beyond the old approach (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

Zimbabwe: Country Marks World TB Day
[The Herald] Tomorrow, Zimbabwe joins the world to commemorate World TB Day. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

Liberia: Pres. Weah Declares Today 'World TB Day'
[New Dawn] -Calls on Liberians to join in observance to create awareness (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

Nigeria: World Tuberculosis Day - How Covid-19 Is Affecting TB Treatment, Intervention
[Premium Times] About 1.4 million people lost out on treatment for tuberculosis in 2020 compared with the previous year, because of COVID-19. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

University of Bristol continues fight to eradicate deadly disease on World Tuberculosis Day
Researchers at the University of Bristol are working on a number of different developments to finally end the TB epidemic. (Source: University of Bristol news)
Source: University of Bristol news - March 24, 2021 Category: Universities & Medical Training Tags: Research; Faculty of Science, School of Physics, Faculty of Science, School of Chemistry, Faculty of Life Sciences, School of Cellular and Molecular Medicine, Faculty of Life Sciences, School of Biochemistry; Press Release Source Type: news

Nigeria: Tuberculosis - Nigeria Far From Achieving Its 2025 Target, Says WHO
[Vanguard] Abuja -- THE World Health Organisation, WHO, Tuesday, regretted that low Tuberculosis case detection was a major challenge in the disease's control efforts in Nigeria given that the country has detected only 27% of the estimated incident TB cases. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

Johnson & Johnson Announces Five Initiatives to Help Find the ‘Missing Millions’ of Undiagnosed People Living with Tuberculosis
NEW BRUNSWICK, N.J., 24 March 2021 – In recognition of World Tuberculosis (TB) Day, Johnson & Johnson today announced a series of new commitments and collaborations in support of global efforts to find and deliver care to the millions of adults and children living with TB who have not yet been diagnosed. Successfully identifying these people, especially those living with multidrug-resistant TB (MDR-TB), remains one of the most significant obstacles in achieving the United Nations (UN) Sustainable Development Goal of ending TB by 2030. These initiatives—together with the Global Fund to Fight AIDS, Tuberculos...
Source: Johnson and Johnson - March 24, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Nigeria: Nigeria and Global Fund Launch New Grants to Fight HIV, TB and Malaria
[Global Fund] Abuja -- Nigeria and the Global Fund to Fight AIDS, Tuberculosis and Malaria have launched three new grants to strengthen the fight against HIV, TB and malaria and build resilient and sustainable systems for health. (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - March 24, 2021 Category: Infectious Diseases Source Type: news

South Africa: World TB Day - Let's Seize This Moment to Change the Status Quo
[spotlight] This World Tuberculosis (TB) Day, we divert our attention momentarily away from the novel coronavirus (SARS-CoV2) epidemic and refocus on a disease that has plagued us for considerable time, causing mortality of similar proportions seen with SARS-CoV2 in 2020, and close to a billion deaths historically. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news

Nigeria: World TB Day - Experts Laments High Rate of Infection, As Benue Tops List in North Central
[Leadership] Makurdi -- Benue State Government has disclosed that the State has fall in the category of States in Nigeria with very high burden of Tuberculosis (TB), ranking 6th nationally and First in North Central Zone of the Country. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 24, 2021 Category: Infectious Diseases Source Type: news