Where To Track COVID-19 Vaccinations
In 2020 – or the year that drew so many parallels to the dystopian sci-fi show Black Mirror that its creators decided to write a comedy instead – we were all in a race. A race to curb the novel coronavirus’ spread and “flatten the curve”; with dismal results. In 2021, we are yet in another race. A race to vaccinate the world. It was the news (or more likely, the miracle) we were eagerly waiting for: to have a functional vaccine against COVID-19 as soon as possible. And in less than a year since the WHO declared the state of pandemic, we have more than one such vaccine. Records were br...
Source: The Medical Futurist - January 12, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Covid-19 Artificial Intelligence in Medicine Biotechnology Digital Health Research Future of Medicine Healthcare Design tracking vaccination 2020 WHO vaccine Oxford 2021 pfizer BioNTech resources Sputnik-V Moderna Astra Source Type: blogs

What infectious diseases are due to be eradicated next?
  Although Medical Science aims to eradicate Infectious Diseases in order to protect life and reduce the healthcare burden, it has only been able to achieve that goal against two diseases to date. While this remains a difficult task, there is a genuine possibility that additional diseases will be eliminated in the near future! Let’s explore the diseases that have been consigned to history…and those that are set to join them soon. Smallpox: declared eradicated in 1980 Following a concentrated global effort spanning more than 20 years, Smallpox became the first infectious disease to be eradicated by mankind...
Source: GIDEON blog - December 23, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Source Type: blogs

8 Digital Health Technologies Transforming The Future Of Nurses
Being a nurse is a highly demanding but genuinely fulfilling job with the chance to touch many people’s lives. This hasn’t been highlighted better than during the COVID-19 pandemic. When the whole world is stricken by fear and uncertainty, with many under lockdown 2.0, nurses are actively in the front line assisting patients and physicians. As the nursing profession requires the core of what makes us human – paying attention, being empathetic and caring -, it will never be replaced by technology.  However, technological innovations can relieve nurses of the burden of many monotonous and repetitive ta...
Source: The Medical Futurist - December 15, 2020 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Future of Medicine Robotics 3d printing AI artificial intelligence digital health Health 2.0 nurse Personalized medicine technology digital technology nurses Source Type: blogs

Inside Schizophrenia: Evolution of Schizophrenia Treatments
Schizophrenia has been around since the dawn of time but actually treating it has only been around the past 100 years. In this episode host and schizophrenic Rachel Star Withers takes you through the dark and disturbing evolution of schizophrenia treatments. From systematic euthanasia to hydrotherapy, electroconvulsive therapy to the infamous lobotomy. Were these doctors “mad scientists” torturing the mentally ill or were they the only ones trying to help a population of people seen as a burden? About our Guest Miriam Posner is an assistant professor at the UCLA School of Information. She holds a Ph.D. in Film ...
Source: World of Psychology - December 9, 2020 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Brain and Behavior General History of Psychology Inside Schizophrenia Mental Health and Wellness Psychiatry Psychotherapy Brain Disorders ECT Electric shock Electroconvulsive Therapy Frontal Lobotomies History Of Mental Illness H Source Type: blogs

Resisting Public Health Measures, Then and Now
One of the most surprising aspects of the Covid-19 pandemic for those of us who teach the history of public health is how unwilling many Americans have been to adopt health measures to protect others. Over the Thanksgiving holiday, tens of millions of Americans traveled, despite the fact that the Centers for Disease Control and Prevention urged them to stay home and the overall death rate from the coronavirus is approaching 300,000. Should recent events make us revisit aspects of the history of public health? And how can these stories inform future public health efforts during pandemics? The post Resisting Public Health Me...
Source: blog.bioethics.net - December 2, 2020 Category: Medical Ethics Authors: Susan Gilbert Tags: Health Care Public Health COVID-19 Hastings Bioethics Forum history of medicine Pandemic Planning syndicated tuberculosis Source Type: blogs

Nasal Endoscopy for Urgent and Complex ED Cases
​Fiberoptics and endoscopy have changed the way we treat patients in the emergency department. Endoscopes are relatively easy to use, and can aid your diagnosis and treatment plan. Endoscopy may be useful in urgent cases, such as epistaxis, nasal foreign bodies, and ear debridement. It may also be helpful when dealing with more complicated presentations and critically ill patients, such as those with Ludwig's angina, epiglottis, tracheostomies, or those who need intubation.Fiberoptic tools are not just for surgeons and consultants. The endoscope has many uses in the emergency department, and we have a few tips and tricks...
Source: The Procedural Pause - October 28, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Rabies – a dumb disease
Dog vaccination programs are the most effective way to prevent Rabies   Rabies is endemic to over 150 countries, and according to the World Health Organization, 99% of all transmissions to humans are from dogs, potentially bringing into question the animal’s status as the ‘man’s best friend’.  In Europe, southern Africa, and parts of North America, most cases are acquired from wild carnivores; mongooses, and vampire bats in Latin America and the Caribbean. In more recent years, humans have acquired rabies from inhalation of aerosols in bat caves, ingestion of dogs and cats for food, ticks...
Source: GIDEON blog - September 28, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Source Type: blogs

Streptomyces – the smell of life
The Mall in Central Park, New York City in late autumn on a rainy day   Did you know that humans can detect the smell of wet soil 200,000 times better than sharks sense blood? [1] It appears our olfactory abilities are not that bad after all, at least when it comes to finding potential sources of food. Petrichor, the term to describe the scent was coined in 1964, by scientists I. Bear and R.G. Thomas, meaning “petros” – stone and “ichor” – the blood of the gods [2] in Greek. Divine or not, Streptomyces is a genus of over 800 bacterial species and subspecies responsible for the eart...
Source: GIDEON blog - September 15, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology Microbiology News Source Type: blogs

The Top 100 Digital Health Companies: An Infographic
According to some estimates, the global digital health market is expected to exceed $504.4 billion by 2025; that’s a nearly six-fold increase from its $86.4 billion 2018 valuation. The COVID-19 pandemic has accelerated both the adoption of and the innovation in digital health and will propel this growth in the coming years. The current situation led to the widespread adoption of telemedicine; people are using digital health apps to stay physically and mentally healthy while indoors; governments are promoting contact tracing apps to limit the virus’ spread. This increased adoption of digital health solutions ...
Source: The Medical Futurist - September 10, 2020 Category: Information Technology Authors: Prans Tags: 3D Printing Artificial Intelligence Augmented Reality Biotechnology Digital Health Research E-Patients Future of Medicine Future of Pharma Genomics Health Sensors & Trackers Healthcare Design Nanotechnology Personalized Medicine Source Type: blogs

New Cato Book: Ten Global Trends Every Smart Person Should Know: And Many Others You Will Find Interesting
In conclusion, I hope that you will buy this book and share it with your family and friends. It is meant to be a conversation piece. Instead of gathering dust on a bookshelf, it is designed to lie on a living room table (like so many architecture and interior design books), for visitors to see and discuss over a martini or glass of wine. I hope that it will alleviate some depression and anxiety, spark a fact ‐​filled discussion around the dining room table, and maybe even change some minds. Strangers things have happened. Cheers! (Source: Cato-at-liberty)
Source: Cato-at-liberty - August 31, 2020 Category: American Health Authors: Marian L. Tupy Source Type: blogs

Sacral Tuberculosis
Here is a case of 35 year Indian origin male with backache with MRI revealed marrow edema in the sacral vertebral bodies along with presacral abscess noted on sagittal fat suppressed images. Interestingly before the MRI Xray didnot show much changes. In patients with osteomyelitis, MRI will pick up the changes earlier than plain xray.MRI SHOWING SARCAL EDEMA& PRESACRAL ABSCESS                              XRAY LS SPINE LATERAL VIEW Famous Radiology Blog http://www.sumerdo...
Source: Sumer's Radiology Site - August 2, 2020 Category: Radiology Authors: Sumer Sethi Source Type: blogs

The Present And Future Of Digital Pills
Flicking your wrist as your smartwatch nudges you, you find a notification alerting that it’s time to take your digital pill. You grab one from your smart medicine pack, alert your GP, and ingest it with a glass of water. Thereafter, the pill broadcasts a real-time video stream as it goes down your oesophagus and into your stomach. Your GP is simultaneously monitoring the visuals, assessing the progression of your ulcer.  Afterwards, you have a video call with your GP who reassures you of the ulcer’s healing. She also notes that the digital pill contains your personalised medicine 3D-printed onto it and...
Source: The Medical Futurist - July 21, 2020 Category: Information Technology Authors: Prans Tags: 3D Printing Health Sensors & Trackers Personalized Medicine schizophrenia digital pill otsuka abilify pillcam patch etectRx infarmate hipaa Source Type: blogs

A Conversation with John Ioannidis
By SAURABH JHA, MD The COVID-19 pandemic has been a testing time for the already testy academic discourse. Decisions have had to be made with partial information. Information has come in drizzles, showers and downpours. The velocity with which new information has arrived has outstripped our ability to make sense of it. On top of that, the science has been politicized in a polarized country with a polarizing president at its helm. As the country awoke to an unprecedented economic lockdown in the middle of March, John Ioannidis, professor of epidemiology at Stanford University and one of the most cited physician sc...
Source: The Health Care Blog - July 9, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Public Health John Ioannidis Saurabh Jha Source Type: blogs

Digital Health Ventures That Flew Too Close To The Sun
1.5 billion: that’s the number, in dollars, Forbes put for Proteus’ valuation last year. Dubbed as a healthcare unicorn, the startup even raised over $500 million in venture capital. It made headlines for developing the first-ever FDA-approved digital pill, one equipped with an ingestible and trackable sensor to monitor treatment compliance.  Researchers even proved the technology’s worth. In 2019, an independent study investigated the Proteus’ digital pill. They found it to be accurate, and even improved adherence of tuberculosis patients using oral pills equipped with Proteus’ s...
Source: The Medical Futurist - July 7, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Future of Medicine Future of Pharma Genomics AI cancer IBM google deepmind theranos Watson fail digital pill proteus deus ex machina tech giants finances otsuka Nightingale Source Type: blogs

Fight Aging! Newsletter, July 6th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - July 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Far Too Little Consideration is Given to the Failure of the Immune System in the Old
There is no situation so terrible that it will not be silently accepted as set in stone, only given that it has lasted for long enough to become routine. So it is with aging, and all of the pain, suffering, and death that accompanies it. The present furor surrounding COVID-19 is unusual for casting at least a little light upon the point that infectious disease largely kills older people, and in very large numbers, year in and year out. In the normal course of affairs, no-one cares until it is their turn to be old, frail, and vulnerable. The immune system decays with age, becoming simultaneously overactive (inflammag...
Source: Fight Aging! - July 3, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Contact Tracing: 10 Unique Challenges of COVID-19
Conclusion The story of COVID-19 contact tracing is still in progress, and it’s not clear whether the ending will be success or failure. We hope that this essay has added depth to the opening words “Contact tracing for COVID-19 will be the most complex health investigation ever”. Vince Kuraitis, JD/MBA (@VinceKuraitis) is an independent healthcare strategy consultant with over 30 years’ experience across 150+ healthcare organizations. He blogs at e-CareManagement.com. Eric D. Perakslis, PhD (@eperakslis) is a Rubenstein Fellow at Duke University. Deven McGraw , JD, MPH, LLM (@h...
Source: The Health Care Blog - June 12, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy The Health Data Goldilocks Dilemma: Sharing? Privacy? Both? Deven McGraw Eric Perakslis Vince Kuraitis Source Type: blogs

Here ’ s How You Can Define ‘ Being Nice ’ on Your Own Terms
“Don’t trade your authenticity for approval.” ~ Unknown As a nice person, I am often conflicted because sometimes I don’t enjoy being nice. Sometimes I act nice out of moral obligation or because I’m trying to be consistent with my perceived identity. Do you view yourself as “nice”? Do others describe you as “nice”? Do you always enjoy being “nice”? If you are unsure how you are perceived by others, ask friends and family to describe you. I’ve been told how nice I am all my life, by family, friends, coworkers, and even bosses. It was a huge part of my...
Source: World of Psychology - June 6, 2020 Category: Psychiatry & Psychology Authors: Psych Central Guest Author Tags: Personal Personality Publishers Self-Help Tiny Buddha Authenticity Being nice people pleaser personal identity Source Type: blogs

What's new in midwifery - 3rd June 2020
Some things you may need to know.  Nothing last week as I was " on holiday " , so two weeks'worth this time.COVID-19A systematic scoping review of COVID-19 during pregnancy and childbirth (International Journal of Obstetrics and Gynecology)ResearchProgression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis (BMJ)**Leicester authors**Comparative impact of pharmacological treatments for gestational diabetes on neonatal anthropometry independent of maternal glycaemic control: A systematic review and meta-analysis (PLoS Medicine)Maternal cardiovas...
Source: Browsing - June 3, 2020 Category: Databases & Libraries Tags: midwifery Source Type: blogs

The new words from the coronavirus pandemic
With any new illness comes metaphor. It is humanity ’s attempt to incorporate the mystery of disease into our own stories. We like to personify illness, give it human characteristics as a way of visualizing it. We name its actions to help lessen its unpredictability. Tuberculosis consumed. Syphilis punished. AIDS invaded. Cancer grows. COVID-19 qua rantines separate […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 28, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/susan-maclellan-tobert" rel="tag" > Susan MacLellan-Tobert, MD < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs

Why Some Countries Have Fared Better in Fighting COVID-19
There are more than 1.2 million confirmed cases of COVID-19 in the United States right now with nearly 80,000 related deaths on record. This number is greater than a quarter of the total deaths suffered worldwide.  What has America gotten wrong in its response to the deadly virus, and what have other countries done right?   New Zealand, South Africa, and Vietnam—even sharing a border with China where the virus originated —all have experienced relatively few cases and minimal deaths from COVID-19.  Our co-founder and infectious disease expert, Dr. Stephen Berger shared his thoughts ...
Source: GIDEON blog - May 12, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: News Press Source Type: blogs

Tree in Bud Appearance: CT
This is 13 year old child with mother who is sputum positive for TB. CT scan shows Tree in Bud lesions showing an appearance of multiple areas of centrilobular nodules with a linear branching pattern. This finding is considered classical for endobronchial TB as in this case. However, has been described in other conditions as well.Tree in Bud appearance Endobronchial infections like pulmonary tuberculosis, bronchiolitis, bronchiectasis with mucus plugging in cystic fibrosis are other classical causes.Famous Radiology Blog http://www.sumerdoc.blogspot.com TeleRad Providers at www.teleradproviders.com Mail us ...
Source: Sumer's Radiology Site - May 11, 2020 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Can AI and radiographs help in resource-poor areas for the fight against COVID-19?
Conclusion  With new evidence emerging every day and with COVID-19 guidance and protocols adapting responsively, the national responses vary widely across the globe. However, Singapore, Taiwan and South Korea have shown that aggressive and proactive testing plays a crucial role in containing the spread of the disease.  We believe AI has great potential for helping doctors quantify and monitor COVID progression from a patient’s chest X-rays – this will help determine treatment pathways faster and thus slow any surges in emergency cases. AI will also play a critical role in expanding screening for...
Source: The Health Care Blog - May 7, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Tech bhargava reddy manoj tld pooja rao preetham srinivas qure.ai tarun raj Source Type: blogs

Harvard Health AdWatch: An arthritis ad in 4 parts
Perhaps you’ve grown as weary as I have of repeated arthritis ads. They appear in frequent rotation on television, online, and in magazines, promoting Enbrel, Humira, Otezla, Xeljanz, and others. If you’ve actually read or listened to these ads, you might have felt perplexed at certain points. Here’s a quick rundown on what they’re saying — and not saying — in one of those ads. “The clock is ticking” Part 1: A teakettle whistles on the stove and a disembodied voice speaks as this ad for Humira opens. “This is your wakeup call. If you have moderate to severe rheumatoid a...
Source: Harvard Health Blog - April 29, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Arthritis Bones and joints Health Inflammation Source Type: blogs

Harvard Health Ad Watch: An arthritis ad in 4 parts
Perhaps you’ve grown as weary as I have of repeated arthritis ads. They appear in frequent rotation on television, online, and in magazines, promoting Enbrel, Humira, Otezla, Xeljanz, and others. If you’ve actually read or listened to these ads, you might have felt perplexed at certain points. Here’s a quick rundown on what they’re saying — and not saying — in one of those ads. “The clock is ticking” Part 1: A teakettle whistles on the stove and a disembodied voice speaks as this ad for Humira opens. “This is your wakeup call. If you have moderate to severe rheumatoid a...
Source: Harvard Health Blog - April 29, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Arthritis Bones and joints Health Inflammation Source Type: blogs

Leadership During a Healthcare Crisis: Kaiser Permanente ’s Response to COVID-19
A Conversation with Dr. Richard Isaacs, CEO of The Permanente Medical Group and the Mid Atlantic Permanente Medical Group By AJAY KOHLI, MD Organizations aren’t built in crises. Their mettle, their history and their leadership define how organizations adapt and succeed, particularly in difficult times. Of the three, the most important quality is leadership. In this regard, Kaiser Permanente is leading the way in healthcare delivery. I had the opportunity to speak with Dr. Richard Isaacs, CEO of The Permanente Medical Group and The MidAtlantic Permanente Medical Group, to discuss the strategic vision an...
Source: The Health Care Blog - April 14, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Hospitals Medical Practice Ajay Kohli Kaiser Permanente Mid Atlantic Permanente Medical Group Pandemic Richard Isaacs Source Type: blogs

Health Care Scope of Practice Laws Reveal Another Weakness in Response to COVID-19 Pandemic
Jeffrey A. SingerOn March 24 Arizona Governor Doug Ducey issuedanexecutive order allowing CRNA ’s (Certified Registered Nurse Anesthetists) to practice independently of physicians or surgeons, thus adding needed personnel to the health care work force during this public health emergency. Guidelines issued by the Centers for Medicare and Medicaid Services state that nurse anesthetists should be “supervised” by a physician, thus preventing these well ‐​trained specialized nurses from providing anesthesia independently while freeing up physician anesthesiologists so more patients can receive ca...
Source: Cato-at-liberty - March 26, 2020 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs

SI Joint TB - Teaching Video
Presenting a brief teaching video on SI joint Tuberculosis and its Radiological findings.Famous Radiology Blog http://www.sumerdoc.blogspot.com TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com (Source: Sumer's Radiology Site)
Source: Sumer's Radiology Site - March 24, 2020 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Time to redefine normal body temperature?
In this study, researchers analyzed temperature recordings from three periods of time over 157 years: 1860–1940: A mix of armpit and oral temperatures of nearly 24,000 veterans of the Civil War were measured. 1971–1975: Oral temperatures of more than 15,000 people from a large population study (the National Health and Nutrition Examination Survey) were analyzed. 2007–2017: Oral temperatures of more than 150,000 people in another large research project (the Stanford Translational Research Integrated Database Environment) were reviewed. During the nearly 160 years covered by the analysis, the average oral...
Source: Harvard Health Blog - March 13, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Children's Health Cold and Flu Men's Health Women's Health Source Type: blogs

Pandemic Fears: What the AIDS Battle Should Teach Us About COVID-19
By ANISH KOKA, MD As the globe faces a novel, highly transmissible, lethal virus, I am most struck by a medicine cabinet that is embarrassingly empty for doctors in this battle.  This means much of the debate centers on mitigation of spread of the virus.  Tempers flare over discussions on travel bans, social distancing, and self quarantines, yet the inescapable fact remains that the medical community can do little more than support the varying fractions of patients who progress from mild to severe and life threatening disease.  This isn’t meant to minimize the massive efforts brought to bear to keep...
Source: The Health Care Blog - March 12, 2020 Category: Consumer Health News Authors: Christina Liu Tags: CORVID-19 Health Policy Patients Physicians AIDS Anish Koka AZT coronavirus COVID-19 FDA novel coronavirus Pandemic Source Type: blogs

Using Ultrasound for Paracentesis
​Paracentesis can be a quick and simple procedure with the right equipment and a well-rehearsed approach. It's important to practice this skill in the procedure lab and to familiarize yourself with the kit in your department a few times a year. This month, we focus on paracentesis set-up and basics, and next month we will review the nuts and bolts of completing the procedure.Important equipment for paracentesis: Five or six collection bottles, antiseptic prep, and a paracentesis kit. Consider longer needles for abdominal walls thicker than 2.5 cm.Grab the ultrasound and a pen. Position your patient at a 45-degree angle, ...
Source: The Procedural Pause - February 3, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Artificial Intelligence vs. Tuberculosis – Part 2
By SAURABH JHA, MD Clever Hans Preetham Srinivas, the head of the chest radiograph project in Qure.ai, summoned Bhargava Reddy, Manoj Tadepalli, and Tarun Raj to the meeting room. “Get ready for an all-nighter, boys,” said Preetham. Qure’s scientists began investigating the algorithm’s mysteriously high performance on chest radiographs from a new hospital. To recap, the algorithm had an area under the receiver operating characteristic curve (AUC) of 1 – that’s 100 % on multiple-choice question test. “Someone leaked the paper to AI,” laughed Manoj. “I...
Source: The Health Care Blog - January 24, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Health Technology @roguerad AI Saurabh Jha TB tuberculosis Source Type: blogs

Fight Aging! Newsletter, January 20th 2020
This study provides strong evidence that following a healthy lifestyle can substantially extend the years a person lives disease-free." Commentary on Recent Evidence for Cognitive Decline to Precede Amyloid Aggregation in Alzheimer's Disease https://www.fightaging.org/archives/2020/01/commentary-on-recent-evidence-for-cognitive-decline-to-precede-amyloid-aggregation-in-alzheimers-disease/ I can't say that I think the data presented in the research noted here merits quite the degree of the attention that it has been given in the popular science press. It is interesting, but not compelling if its role...
Source: Fight Aging! - January 19, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Theorizing on Historical Trends in Body Temperature, Burden of Inflammation, and Life Expectancy
In this study, we analyzed 677,423 human body temperature measurements from three different cohort populations spanning 157 years of measurement and 197 birth years. We found that men born in the early 19th century had temperatures 0.59°C higher than men today, with a monotonic decrease of -0.03°C per birth decade. Temperature has also decreased in women by -0.32°C since the 1890s with a similar rate of decline (-0.029°C per birth decade). Although one might posit that the differences among cohorts reflect systematic measurement bias due to the varied thermometers and methods used to obtain temperatures, we...
Source: Fight Aging! - January 17, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Ride the Fluid Wave Before Performing a Paracentesis
​Before you break out the bottles for a paracentesis, you may want to consider doing a test for ascites. Many procedures require executing an old-school test before even looking at a result or grabbing an ultrasound machine. Knowing what to look for on a physical exam may guide your practice and intervention dramatically. Using noninvasive tools first could help your patient avoid other tedious or unnecessary testing, which may also result in lost time. Incorporating ultrasound into your practice may also help you nail a diagnosis or allow you to perform a procedure better than you expected.A markedly distended abdomen d...
Source: The Procedural Pause - January 2, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

A Look Back at 2019
I've always been an optimist.  I believe humans are basically good and that the nice guy will win eventually.After traveling 400,000 miles to 40 countries in 2019, helping government, academia, and industry, my view of the world has not changed.Despite our focus on the negative 24x7 news cycle, 2019 has been thebest year for humanity in history.My best memories, looking back at 2019:*Serving the Gates Foundation in South Africa and Northern India.  Experiencing the rollout of technology enabled platforms that reduced HIV disease burden and improved diagnosis/treatment of tuberculosis.*Working with mayors and...
Source: Life as a Healthcare CIO - December 31, 2019 Category: Information Technology Source Type: blogs

Artificial Intelligence vs. Tuberculosis, Part 1
By SAURABH JHA, MD Slumdog TB No one knows who gave Rahul Roy tuberculosis. Roy’s charmed life as a successful trader involved traveling in his Mercedes C class between his apartment on the plush Nepean Sea Road in South Mumbai and offices in Bombay Stock Exchange. He cared little for Mumbai’s weather. He seldom rolled down his car windows – his ambient atmosphere, optimized for his comfort, rarely changed. Historically TB, or “consumption” as it was known, was a Bohemian malady; the chronic suffering produced a rhapsody which produced fine art. TB was fashionable in Victorian Britain...
Source: The Health Care Blog - December 5, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Saurabh Jha TB tuberculosis Source Type: blogs

Fight Aging! Newsletter, November 4th 2019
In this study, we hypothesized that moderately and chronically reducing ACh could attenuate the deleterious effects of aging on NMJs and skeletal muscles. To test this hypothesis, we analyzed NMJs and muscle fibers from heterozygous transgenic mice with reduced expression of the vesicular ACh transporter (VAChT), VKDHet mice, which present with approximately 30% less synaptic ACh compared to control mice. Because ACh is constitutively decreased in VKDHet, we first analyzed developing NMJs and muscle fibers. We found no obvious morphological or molecular differences between NMJs and muscle fibers of VKDHet and contro...
Source: Fight Aging! - November 3, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Perspective on Longevity Biotech Investment from James Peyer of Kronos BioVentures
James Peyer, formerly of Apollo Ventures and now at the larger Kronos BioVentures, has a range of interesting views on the new and growing longevity biotechnology industry. Apollo Ventures was one of the earlier longevity-focused funds to emerge from the comparatively small community of scientists, patient advocates, and investors enthusiastic to accelerate progress towards the treatment of aging as a medical condition. The presentation here was given earlier this year at the Ending Age-Related Diseases conference organized by the Life Extension Advocacy Foundation. In the matter of creating new medical therapies, t...
Source: Fight Aging! - October 30, 2019 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Ping Pong Balls in the Lungs
​"She's worried I had a heart attack."That was the answer I got from the 70ish-year-old patient pointing at his wife when I asked why he came to the emergency department. She quickly added, "He had terrible pain four days ago on the right side, and now he gets winded when he walks."I had already seen his ECG, so I assured her that it appeared normal. I was going to order a chest x-ray, however, because his lungs sounds were pretty quiet. She said he had COPD, and wanted to know if he needed an inhaler.The last time I had seen something like this was in medical school 30 years ago. At that time, I was ...
Source: Lions and Tigers and Bears - October 1, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Indigenous Medicine – From Illegal to Integral
Brooke Warren Phuoc Le By PHUOC LE, MD and BROOKE WARREN In the 2020 Summer Olympics, we will undoubtedly see large, red circles down the arms and backs of many Olympians. These spots are a side-effect of cupping, a treatment originating from traditional Chinese medicine (TCM) to reduce pain. TCM is a globally used Complementary and Alternative Medicine (CAM), but it still battles its critics who think it is only a belief system, rather than a legitimate medical practice. Even so, the usage of TCM continues to grow. This led the National Institute of Health (NIH) to sponsor a meeting in 1997 to determine...
Source: The Health Care Blog - September 25, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Arc Health Brooke Warren complementary and alternative medicine cupping indigenous medicine Phuoc Le TCM traditional chinese medicine Source Type: blogs

There ’s a new cure for the deadliest strain of tuberculosis. So what’s that mean for the REACH Initiative’s HIV research in South Africa?
“This strain of tuberculosis (TB) is XDR-TB – extremely drug resistant tuberculosis– and is, as the name implies, highly resistant to the standard treatments,” says professor and TB/HIV expert Jason Farley, PhD, MPH, ANP-BC, AACRN, FAAN. HIV weakens the immune system, increasing the risk of TB in people with HIV. Dr. Farley’s Center, The REACH The post There’s a new cure for the deadliest strain of tuberculosis. So what’s that mean for the REACH Initiative’s HIV research in South Africa? appeared first on Johns Hopkins Nursing Magazine. (Source: Nursing Blogs at Johns Hopkins University)
Source: Nursing Blogs at Johns Hopkins University - August 16, 2019 Category: Nursing Authors: Online Editor Tags: On the Pulse antimicrobial resistance hiv REACH initiative TB tuberculosis Source Type: blogs

Even Low Levels of Infection Can Cause Cardiac Dysfunction in Older Individuals
We examined how mycobacterial infection and inflammaging catalyze the decline in cardiovascular function in the elderly. Young (3 months) and old (18 month) female C57BL/6 mice were infected with a sub-lethal dose of Mycobacterium avium (M. avium), an NTM. We observed no differences in the M. avium bacterial numbers in the lung, liver, or spleen between young and old M. avium infected mice. However, through the course of M. avium infection, old mice developed severe dysrhythmia and developed pericarditis. Moreover, the hearts of M. avium infected old mice had increased cardiac hypertrophy, fibrosis, expression of pro-infla...
Source: Fight Aging! - August 9, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

RNA Polymerase: A Target for New Antibiotic Drugs?
DNA, with its double-helix shape, is the stuff of genes. But genes themselves are only “recipes” for protein molecules, which are molecules that do the real heavy lifting (or do much of the work) inside cells. Artist interpretation of RNAP grasping and unwinding a DNA double helix. Credit: Wei Lin and Richard H. Ebright. Here’s how it works. A molecular machine called RNA polymerase (RNAP) travels along DNA to find a place where a gene begins. RNAP uses a crab-claw-like structure to grasp and unwind the DNA double helix at that spot. RNAP then copies (“transcribes”) the gene into messe...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 7, 2019 Category: Research Authors: Chrissa Chverchko Tags: Genes Bacteria Cellular Processes DNA Infectious Diseases Medicines Proteins RNA Source Type: blogs

Is it SAFE to be grain-free?
Listen to critics of the Wheat Belly lifestyle and you’d think that, by banishing all things wheat and grains from your life, you will be excommunicated from your church, tossed out of your club, ostracized by friends and family, and suffer dire health consequences like heart disease and colon cancer. After all, they say that you are eliminating an entire food group and will be crippled by lack of fiber and nutrients. Worse, our focus on increasing our intake of fats and oils will get you a heart attack, three stents, or bypass surgery and you’ll be obliged to take Lipitor and Repatha for a lifetime. First of a...
Source: Wheat Belly Blog - June 25, 2019 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle grain-free Weight Loss Source Type: blogs

Why A Diverse and Inclusive Healthcare Innovation Workforce Matters
By ANDRÉ BLACKMAN There I was, my 10th-grade science fair. My mother made sure I had a tie that fit properly and a shirt that was perfectly pressed. I stood among my peers with our cardboard presentation displays highlighting what we did to make it to this point. I was a little nervous but also extremely proud of myself and excited to see the looks on the judge’s faces when they saw what my project was about: “The Effects of Enzymes on DNA” Boom. Oh, I wasn’t doing something that many people had seen already — I was working inside an NIH facility with a brilliant scient...
Source: The Health Care Blog - June 12, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Health Technology digital health Diversity Healthcare Hiring inclusion talent workforce; Source Type: blogs

AI Platform for Cognitive Performance Training
This study, published in journal Advanced Therapeutics, describes the use of CURATE.AI for improving trainee performance on a US Air Force flight simulator program, a task that is very cognitively challenging. In the past, the same research team used the CURATE.AI software to develop a personalized immunosuppressant dosing schedule after organ transplant, optimize drug discovery libraries, and study in vitro and in vivo models of disease, including multiple myeloma and tuberculosis. In the study, participants underwent training with the flight simulator in low, medium, and high intensity levels. CURATE.AI characterized the...
Source: Medgadget - June 10, 2019 Category: Medical Devices Authors: Siavash Parkhideh Tags: Education Informatics Net News Psychiatry Source Type: blogs

Fight Aging! Newsletter, May 27th 2019
In this study, we found that cofilin competes with tau for direct microtubule binding in vitro, in cells, and in vivo, which inhibits tau-induced microtubule assembly. Genetic reduction of cofilin mitigates tauopathy and synaptic defects in Tau-P301S mice and movement deficits in tau transgenic C. elegans. The pathogenic effects of cofilin are selectively mediated by activated cofilin, as active but not inactive cofilin selectively interacts with tubulin, destabilizes microtubules, and promotes tauopathy. These results therefore indicate that activated cofilin plays an essential intermediary role in neurotoxic signaling th...
Source: Fight Aging! - May 26, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs