Another Outbreak of TB Linked to Contaminated Bone Grafts
(MedPage Today) -- Contaminated bone allograft material from a single manufacturer led to five diagnosed cases of tuberculosis (TB) and two deaths so far, according to CDC data. In July, clinicians in two different states rapidly diagnosed and... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - January 4, 2024 Category: American Health Source Type: news

Malawi: Congestion Spreading TB in Malawi Prisons
[Nyasa Times] Malawi Prison Services (MPS) has cited congestion as the major contributing factor in the spread of tuberculosis (TB) in the country's prisons. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - January 3, 2024 Category: Infectious Diseases Tags: Health and Medicine Legal and Judicial Affairs Malawi Southern Africa Tuberculosis Source Type: news

ChatGPT perpetuates racial and gender biases
ChatGPT-4 consistently produces clinical vignettes that stereotype certain races, ethnicities, and genders, according to a study published in the January issue of The Lancet: Digital Health.The findings highlight an urgent need for comprehensive and transparent bias assessments of LLM tools such as GPT-4 before they are integrated into clinical care, wrote a team led by Travis Zack, PhD, of the University of California, San Francisco.“Our results underscore the need for caution in deployment of LLMs for clinical applications to ensure LLMs do not further exacerbate health inequities,” the group wrote.Large language mod...
Source: AuntMinnie.com Headlines - January 2, 2024 Category: Radiology Authors: Will Morton Tags: Radiology Education Artificial Intelligence Source Type: news

South Africa: Breakthrough Raspberry TB Meds Available for Children
[SciDev.Net] Nairobi -- A new child-friendly formulation of rifapentine, approved for TB prevention in children, promises easier access and improved treatment outcomes. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 27, 2023 Category: African Health Tags: Children and Youth Health and Medicine Innovation Science and Biotechnology South Africa Southern Africa Sustainable Development Tuberculosis Source Type: news

South Africa: Analysis - SA Close to Meeting TB Research Funding Targets, but Most Countries Falling Short
[spotlight] South Africa is one of only six countries to ever meet its "fair share target" for funding tuberculosis (TB) research, according to a Treatment Action Group (TAG) report published this week. In absolute terms however, South Africa's contribution is small change compared to investments into TB research made by the top two contributors, the United States government and the Bill and Melinda Gates Foundation (BMGF). (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - December 27, 2023 Category: Infectious Diseases Tags: Governance Health and Medicine South Africa Southern Africa Sustainable Development Tuberculosis Source Type: news

Recent TB Infection Rare Among Immigrants to Canada Recent TB Infection Rare Among Immigrants to Canada
Data suggest that few immigrants to Canada with tuberculosis infection were infected within the preceding 2 years, when the risk for progression to tuberculosis disease is the highest.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - December 19, 2023 Category: Allergy & Immunology Tags: Infectious Diseases Source Type: news

TB impairs DNA repair | Science Signaling
A Mycobacterium tuberculosis virulence factor promotes foam cell formation by inhibiting DNA repair. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - December 19, 2023 Category: Science Source Type: news

Liberia: Partners in Health Rescues Patients At National TB Hospital
[FrontPageAfrica] Partner in Health (PIH) Liberia has completed the renovation of sanitary facilities at the National Tuberculosis Hospital in Oldest Congo Town, Monrovia. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 19, 2023 Category: African Health Tags: Health and Medicine Liberia NGOs and Civil Society West Africa Source Type: news

Nigeria: Succour for TB Patients As U.S, ASR Africa Deliver $0.5m Dots Centres in Nigeria
[Vanguard] Towards mitigating the huge burden of tuberculosis in Nigeria, the Abdul Samad Rabiu Africa Initiative, ASR Africa, in partnership with the United States government Agency for International Development, USAID, have renovated 10 Tuberculosis Directly Observed Treatment Short-Course (DOTS) centres in identified Primary Health Care centres across seven states in the country. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 18, 2023 Category: African Health Tags: Health and Medicine Nigeria Tuberculosis West Africa Source Type: news

AuntMinnie.com X-Ray Insider
Dear Digital X-Ray Insider,RSNA 2023 wrapped up in Chicago recently, with a bevy of digital x-ray studies presented at the meeting. We’ve featured one more here: an AI study conducted in Zambia testing an algorithm developed by Google to detect tuberculosis on chest x-rays. The model performed well, and you can read about the study in this issue’s featured article. As expected, AI studies took most of the top headlines from RSNA 2023. The mood at the meeting may have been summed up most succinctly by Sean Raj, MD, of outpatient radiology group SimonMed Imaging: “We’re going all in on AI,” he said, in a presentat...
Source: AuntMinnie.com Headlines - December 14, 2023 Category: Radiology Authors: Will Morton Tags: Digital X-Ray Source Type: news

AI shows promise detecting TB in Zambia
In this study, the researchers evaluated Google AI TB in adults who had symptoms suggestive of TB, who were close contacts of TB patients, or who were newly diagnosed with HIV. They enrolled 1,932 patients at three clinical sites. Of the 1,807 patients with a definitive TB status, 641 (35%) were HIV positive and 190 (11%) were TB positive.The TB AI’s scores were calculated using two prespecified operating points (OP): a high sensitivity OP based on the WHO target product profile (90% sensitivity/70% specificity) and a more balanced OP designed to resemble an average radiologist’s performance (90% sensitivity/50% specif...
Source: AuntMinnie.com Headlines - December 14, 2023 Category: Radiology Authors: Will Morton Tags: Artificial Intelligence Chest Radiology Subspecialties Source Type: news

Nigeria: Succour for TB Patients As U.S., ASR Africa Deliver $0.5m Dots Centres in Nigeria
[Vanguard] Towards mitigating the huge burden of tuberculosis in in Nigeria, the Abdul Samad Rabiu Africa Initiative, ASR Africa, in partnership with the United States Government Agency for International Development, USAID, have renovated 10 Tuberculosis Directly Observed Treatment Short-Course (DOTS) centres in identified Primary Health Care centres across seven states in the country. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - December 14, 2023 Category: Infectious Diseases Tags: Health and Medicine Nigeria Tuberculosis West Africa Source Type: news

South Africa: Health in 2023 - a Deceptively Busy Year in Fewer Than 1 000 Words
[spotlight] 2023 was a busy year for healthcare in South Africa. There were several policy developments, landmark court cases, important pieces of legislation, and some changes in leadership. Yet, take a step back and not much seems to have changed. Shortages of healthcare workers persist, corruption is still rife, budgets tight, and our health governance crisis remains as acute as ever. (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - December 11, 2023 Category: Infectious Diseases Tags: HIV-Aids and STDs Coronavirus Health and Medicine Noncommunicable Diseases South Africa Southern Africa Sustainable Development Tuberculosis Source Type: news

Notes from the Field: Undiagnosed Tuberculosis During Pregnancy Resulting in a Neonatal Death - United States, 2021
This report describes an infant death following a case of undiagnosed tuberculosis during pregnancy. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - December 7, 2023 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Tuberculosis (TB) Tuberculosis Vaccine (BCG) Source Type: news

$20,000 monkeys: inside the booming illicit trade for lab animals
A lucrative underground trade risks undermining research, creating new pandemics and pushing a recently abundant species to the brinkIn 2019, Jonah Sacha, a researcher at Oregon Health and Science University, received a delivery of 20 monkeys from Mauritius. As part of his research into stem-cell transplants as an HIV treatment, he performs tests on long-tailed macaques.The captive-bred monkeys were legally imported using an approved vendor, and looked healthy. However, when Sacha tested them, one appeared to have latent tuberculosis (TB).Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - December 7, 2023 Category: Science Authors: Phoebe Weston Tags: Global development Illegal wildlife trade Environment Animals Endangered species Zoology Biology Conservation Source Type: news