Bharat Biotech starts clinical trials of TB jab
The only vaccine in use today--BCG (Bacillus Calmette and Guerin)--is an attenuated variant of the bovine TB pathogen. This is more than a hundred years old and has a limited effect on pulmonary tuberculosis, which is mostly responsible for the transmission of the disease. Studying the safety, immunogenicity and efficacy of MTBVAC in the most populated country in the world and the one with the highest number of cases of this infectious disease is key to continue advancing in this vaccine," the company said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 24, 2024 Category: Pharmaceuticals Source Type: news

Nursing shortage, overcrowded homes in Pimicikamak Cree Nation make tuberculosis cases difficult to monitor
The chief of a northern Manitoba First Nation says overcrowding and poor access to health-care services in his community can make tuberculosis cases harder to monitor and contain. (Source: CBC | Health)
Source: CBC | Health - March 24, 2024 Category: Consumer Health News Tags: News/Canada/Manitoba Source Type: news

Opening remarks by Dr Hanan Hassan Balkhy, WHO Regional Director for the Eastern Mediterranean, ...
24 March 2024 Thank you for gathering here today on World Tuberculosis Day. As one of the most deadly infectious diseases in the world, TB remains a pressing challenge to all WHO regions. In September 2023, the United Nations General Assembly convened its second high-level meeting on tuberculosis, at which Member States renewed their commitments to advance global, regional and national efforts towards ending the TB epidemic by endorsing a political declaration on TB with ambitious targets for the next five years. Despite the setbacks of the COVID-19 emergency, countries and territories of the WHO Eastern Mediterranean Re...
Source: WHO EMRO News - March 24, 2024 Category: Middle East Health Source Type: news

Bharat Biotech begins clinical trials of TB vaccine on adults in India
Bharat Biotech International Ltd has initiated clinical trials for the Tuberculosis vaccine Mtbvac on adults in India. Developed by the Spanish biopharmaceutical company Biofabri, Mtbvac is the first TB vaccine derived from a human source. The vaccine aims to be more effective and longer-lasting than the current BCG vaccine for newborns and to prevent TB in adults and adolescents, for whom there is currently no effective vaccine. The trials are a significant step, especially in a country like India where 28% of the world's TB cases occur. (Source: The Economic Times)
Source: The Economic Times - March 24, 2024 Category: Consumer Health News Source Type: news

World Tuberculosis Day 2024: many more TB cases could be prevented
24 March 2024, Cairo, Egypt – Tuberculosis (TB) is still one of the world’s deadliest diseases, although it is both preventable and curable. Today, on World Tuberculosis Day, WHO and partners worldwide unite to renew the commitment to end the global TB pandemic. Every year, 10 million people globally fall ill with TB. An infectious disease that mainly affects the lungs but can attack any part of the body. Despite being preventable and curable, TB kills 1.5 million people each year – making it the world’s top infectious killer. TB is also the leading cause of death among people living with HIV and a major cont...
Source: WHO EMRO News - March 23, 2024 Category: Middle East Health Source Type: news

South Africa: MSF Calls for Decentralisation of Life-Saving DR-TB Services in Rural Setting
[MSF] An evaluation report released today by Doctors Without Borders (MSF) charts progress towards decentralizing services for patients with drug-resistant tuberculosis (DR-TB) in South Africa's KwaZulu-Natal's King Cetshwayo District (KCD), in line with the country's 2011 DR-TB decentralization policy. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 22, 2024 Category: Infectious Diseases Tags: Health and Medicine South Africa Southern Africa Tuberculosis Source Type: news

Africa: To End TB, Invest in Drug Discovery In and For Africa
[allAfrica] One hundred and forty-two years after its discovery, Tuberculosis (TB) remains a global public health problem. Despite being preventable and curable, 1.3 million people died from TB in 2022, 424,000 of them in Africa and 54,200 of them in South Africa alone. Statistically, that means one life was lost to TB every 10 minutes in South Africa during that period. It is noteworthy that TB caused by Mycobacterium tuberculosis is the world's leading cause of death from an infectious disease (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 22, 2024 Category: African Health Tags: Africa Health and Medicine South Africa Southern Africa Tuberculosis Source Type: news

Tanzania: With Fresh Momentum, a Pivotal Moment for the Fight Against TB
[Global Fund] In the fight against tuberculosis (TB), we may be on the cusp of an era of remarkable progress. The end of TB may not be here yet, but if the world grabs the momentum we have built in the last two years in the fight against this disease, we can make this moment the beginning of the end of an age-old disease. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 22, 2024 Category: Infectious Diseases Tags: East Africa Health and Medicine Tanzania Tuberculosis Source Type: news

Tuberculosis Preventive Treatment Update - U.S. President's Emergency Plan for AIDS Relief, 36 Countries, 2016-2023
This report describes trends in the initiation and completion of preventive treatment for tuberculosis in people with HIV through PEPFAR-supported programs. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - March 21, 2024 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Tuberculosis (TB) Source Type: news

Active case finding for TB must be paired with effective follow-up care, Cochrane review finds
Door-to-door tuberculosis (TB) screening and contact tracing can improve diagnosis rates, but must be paired with effective follow-up care to be successful, a newCochrane review has found.Active case finding (ACF) seeks to improve diagnosis rates in people living in communities who may not otherwise present to health facilities, helping them access treatment and reduce onward transmission.Despite being a key strategy of most TB strategies globally, there is often little consideration of how these programmes are experienced by communities. This is essential in designing appropriate and effective services.Published ahead of ...
Source: Cochrane News and Events - March 21, 2024 Category: Information Technology Authors: Muriah Umoquit Source Type: news

South Africa: Activists Call On Govt to Declare TB a National Health Crisis
[GroundUp] Though TB is preventable and treatable, more than 50,000 people died of it in South Africa in 2022 (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 21, 2024 Category: African Health Tags: Health and Medicine South Africa Southern Africa Tuberculosis Source Type: news

Africa: WHO Study Shows $39 Return for Each Dollar Invested in Fight Against TB
[UN News] The UN World Health Organization (WHO) on Monday called for a funding boost in tuberculosis (TB) screening and prevention programmes to protect vulnerable populations and achieve key health goals. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 20, 2024 Category: Infectious Diseases Tags: Africa External Relations Health and Medicine International Organizations and Africa Tuberculosis Source Type: news

Africa: Bill & Melinda Gates Medical Research Institute Initiates Phase Three Clinical Trial of Tuberculosis Vaccine Candidate
[Gates Foundation] A large Phase 3 trial will evaluate whether the M72/AS01E vaccine candidate can protect adolescents and adults from pulmonary tuberculosis Clinical trial site at University of the Witwatersrand, Johannesburg, South Africa, is first of up to 60 sites in seven countries The M72/AS01E vaccine candidate could be the first new TB vaccine in 100 years if proven effective (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - March 19, 2024 Category: Infectious Diseases Tags: Africa Health and Medicine Tuberculosis Source Type: news

Africa: Tuberculosis - MSF Launches Unprecedented Project to Tackle Underdiagnosis Among Children
[MSF] Tuberculosis (TB) in children is a silent scourge: one child dies of TB every three minutes and more than half of all children with TB are never diagnosed. Taking the opportunity of a set of new recommendations by the World Health Organisation (WHO), Médecins Sans Frontières (MSF) has launched a worldwide project aiming to increase the number of children diagnosed with TB as well as improve their treatment experience and prevent new cases. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 19, 2024 Category: African Health Tags: Africa Aid and Assistance External Relations Health and Medicine International Organizations and Africa NGOs and Civil Society Tuberculosis Source Type: news

Africa: WHO Urges Investments for the Scale Up of Tuberculosis Screening and Preventive Treatment
[WHO] Ahead of World Tuberculosis (TB) Day, which is marked on 24 March, WHO has released an investment case for TB screening and preventive treatment. A modelling study developed with Governments of four countries - Brazil, Georgia, Kenya and South Africa - highlights the impact to be achieved from expanding TB screening and preventive treatment. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 18, 2024 Category: African Health Tags: Africa External Relations Health and Medicine International Organizations and Africa Source Type: news