Treatment for Latent Tuberculosis Can Be Self-Administered, Study Suggests
Self-administered weekly treatment for latent tuberculosis "may be an acceptable strategy" in the U.S., according to the authors of a noninferiority trial published in... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 9, 2017 Category: Primary Care Source Type: news

Six dead in Minnesota tuberculosis outbreak
A tuberculosis outbreak in Ramsey County, Minnesota, has infected 17 people and killed six. Fourteen of those who contracted the disease are from the elderly Hmong community. (Source: the Mail online | Health)
Source: the Mail online | Health - November 8, 2017 Category: Consumer Health News Source Type: news

Self-Administered Therapy a Viable Option for Latent TB Self-Administered Therapy a Viable Option for Latent TB
Self-administered, once-weekly therapy found to be noninferior to directly observed therapy for patients with latent tuberculosis infection.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 7, 2017 Category: Consumer Health News Tags: Internal Medicine News Source Type: news

Health Highlights: Nov. 7, 2017
Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: Chopin Died from Complications of TB: Researchers Composer Frederic Chopin died from complications of tuberculosis, say researchers who examined... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 7, 2017 Category: General Medicine Source Type: news

Treatment for Latent Tuberculosis Can Be Self-Administered, Study Suggests (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Self-administered weekly treatment for latent tuberculosis " may be an acceptable strategy " in the U.S., according to the authors of a noninferiority trial published in the Annals of Internal Medicine.Some 1000 adults with … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 7, 2017 Category: Primary Care Source Type: news

Chopin ’ s Heart, Pickled in a Jar, Offers Clues to his Death
The heart of the Polish composer, preserved for nearly 170 years, was examined by scientists who say he most likely died of tuberculosis. (Source: NYT Health)
Source: NYT Health - November 6, 2017 Category: Consumer Health News Authors: ANNALISA QUINN Tags: Classical Music Chopin, Frederic American Journal of Medicine Research Tuberculosis Poland Source Type: news

Trial shows most people will complete treatment for latent TB without direct observation
(American College of Physicians) A phase 4 randomized clinical trial found that self-administered treatment for latent tuberculosis infection (LTBI) had a high rate of treatment completion in the United States, Spain, and Hong Kong among a diverse patient population. This is significant because transition from latent TB to active disease accounts for an estimated 86 percent of active TB cases in the United States. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 6, 2017 Category: Infectious Diseases Source Type: news

What Causes White Nails?
Discussion The nail matrix covers the area of the nail plate, and extends proximally in a crescent moon shape with the edges of the crescent extending proximally and inferiorly toward the underlying bone. The nail matrix is a multilayered epithelium that physiologically produces keratinization and gives rise to the nail plate. The distal matrix forms the lower 2/3s of the nail plate and the proximal matrix forms the upper 1/3 of the nail plate. the thickness of the nail plate is proportion to the matrix’s thickness. The nail plate’s free edge contour follows the shape of the nail’s lunula. Melanocytes occ...
Source: PediatricEducation.org - November 6, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Lesotho:Lesotho Registers Gains in TB Fight
[Lesotho Times] LESOTHO has registered modest gains in its war against the highly infectious and deadly tuberculosis (TB) disease amid World Health Organisation (WHO) revelations that the country has achieved a seven percent decline in TB incidence rates since 2010. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - November 4, 2017 Category: Infectious Diseases Source Type: news

Global Tuberculosis Report 2017
World Health Organization. 10/30/2017 This 262-page annual report provides a comprehensive and up-to-date assessment of the tuberculosis (TB) epidemic, and of progress in prevention, diagnosis, and treatment of the disease at global, regional, and country levels. It discusses how TB is the main cause of deaths related to antimicrobial resistance. Multidrug-resistant TB (MDR-TB) remains a public health crisis and a health security threat. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - November 1, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Tuberculosis The End TB Strategy Areas of work TB publications TB data News, events and features About us Global tuberculosis report 2017
The main aim of the report is to provide a comprehensive and up-to-date assessment of the TB epidemic, and of progress in prevention, diagnosis and treatment of the disease at global, regional and country levels. (Source: PHPartners.org)
Source: PHPartners.org - November 1, 2017 Category: International Medicine & Public Health Source Type: news

Nigeria:TB Deaths Drop, but Not Fast Enough to Reach Goal
[Daily Trust] Deaths from tuberculosis fell last year over previous years, but progress against the disease is not fast enough to reach global goals, a new report by the World Health Organisation says. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - November 1, 2017 Category: Infectious Diseases Source Type: news

Solving of a decade long mystery could help in fight against TB
(University of Sussex) Research carried out by the University of Sussex and the Polish Academy of Sciences has identified two key proteins that allow mycobacterium tuberculosis, the causative agent of tuberculosis (TB), to 'lay low' within cells designed to destroy them. It is hoped this discovery will aid in the designing of new antibiotics that could help target mycobacteria, particularly during their latent phase. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 1, 2017 Category: International Medicine & Public Health Source Type: news

Solving of a decade-long mystery could help in fight against TB
(University of Sussex) Research carried out by the University of Sussex and the Polish Academy of Sciences has identified two key proteins that allow mycobacterium tuberculosis, the causative agent of tuberculosis (TB), to 'lay low' within cells designed to destroy them. It is hoped this discovery will aid in the designing of new antibiotics that could help target mycobacteria, particularly during their latent phase. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 1, 2017 Category: Infectious Diseases Source Type: news

Nigeria:Despite Global Efforts, TB Mortality Still High in Nigeria, Others - WHO
[Premium Times] Despite global efforts to reduce the mortality rate of tuberculosis, TB, Nigeria still ranks high among the seven countries which account majorly for the disease globally. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 31, 2017 Category: African Health Source Type: news

GHIT Fund accelerates promising efforts to find new treatments, vaccines and diagnostics
(Burness) The Global Health Innovative Technology (GHIT) Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced US$16.7 million to support development of new compounds for fighting malaria and tuberculosis, a leishmaniasis vaccine and drug, and a treatment for a long-ignored flesh-eating infection. The new investments also will allow scientists to pursue a critically needed diagnostic tool for detecting a relapsing form of malaria when it is hiding in the liver during its dormant phase. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 31, 2017 Category: Infectious Diseases Source Type: news

Diagnostic revolution targets tuberculosis, other deadly diseases
(Arizona State University) In a series of new studies, Tony Hu, a researcher at Arizona State University's Biodesign Institute, describes the development of several new methods for TB diagnosis that improve the speed, accuracy, and cost of TB detection. They should also dramatically improve TB treatment. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 31, 2017 Category: Infectious Diseases Source Type: news

WHO report signals urgent need for greater political commitment to end tuberculosis
WHO report signals urgent need for greater political commitment to end TB (Source: WHO news)
Source: WHO news - October 30, 2017 Category: International Medicine & Public Health Tags: tuberculosis [subject], tb, tuberculosis [subject], tb, Press release [doctype] Source Type: news

A Lot Of People Think This Disease Is Extinct, But It's A Top 10 Killer Globally
Tuberculosis -- a treatable, curable disease -- kills approximately three people a minute. (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - October 30, 2017 Category: Consumer Health News Source Type: news

Tuberculosis world & #39s top infectious killer; UN health agency calls for political action to stop spread
Progress has not been fast enough over the past year to reach global and regional targets on stopping the spread of tuberculosis (TB), or to make real headway in closing persistent gaps in TB care and prevention, the World Health Organization warned Monday. (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - October 30, 2017 Category: International Medicine & Public Health Source Type: news

Tuberculosis world's top infectious killer; UN health agency calls for political action to stop spread
Progress has not been fast enough over the past year to reach global and regional targets on stopping the spread of tuberculosis (TB), or to make real headway in closing persistent gaps in TB care and prevention, the World Health Organization warned Monday. (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - October 30, 2017 Category: International Medicine & Public Health Source Type: news

Who is Really Responsible for Collapse of Zimbabwe ’s Health Services?
Many children under 15 in Zimbabwe discover their HIV status only when they fall critically ill later in life. Credit: Jeffrey Moyo/ IPSBy Frederic MousseauOAKLAND, CALIFORNIA, Oct 27 2017 (IPS)On October 22, 2017, the World Health Organization (WHO) announced that it had removed Zimbabwean president Robert Mugabe as a goodwill ambassador following outrage and concerns raised by his appointment just two days before. A Guardian article cited WHO member states and activists “who noted that Zimbabwe’s health care system, like many of its public services, has collapsed under Mugabe’s regime.” Another ar...
Source: IPS Inter Press Service - Health - October 27, 2017 Category: International Medicine & Public Health Authors: Frederic Mousseau Tags: Africa Featured Headlines Health Indigenous Rights Poverty & SDGs TerraViva United Nations Source Type: news

Personal Stories from TB Survivors - My Journey fighting TB
(Source: WHO Feature Stories)
Source: WHO Feature Stories - October 26, 2017 Category: International Medicine & Public Health Tags: tuberculosis [subject], tb, tuberculosis [subject], tb, Feature [doctype] Source Type: news

Zimbabwe:Influx of Migrants Threatens Country Efforts to End TB
[263Chat] Zimbabwe's aggressive efforts and investment towards eradicating tuberculosis (TB) could all be in vain if nothing is done to ensure screening and continuous treatment of Mozambique nationals fleeing from civil unrest into Zimbabwe. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - October 24, 2017 Category: Infectious Diseases Source Type: news

UMass Amherst microbiologists contribute to possible new anti-TB treatment path
(University of Massachusetts at Amherst) As part of the long effort to improve treatment of tuberculosis (TB), microbiologists led by Yasu Morita at the University of Massachusetts Amherst report that they have for the first time characterized a protein involved in making a glycolipid compound found in the TB cell wall, which is critical for the disease-causing Mycobacterium to become infectious. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 23, 2017 Category: Infectious Diseases Source Type: news

Diabetes Mellitus Overview Video Diabetes Mellitus Overview Video
This video covers the pathophysiology of tuberculosis infection, as well as important complications, signs and symptoms, tests and procedures, and treatment.Osmosis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 20, 2017 Category: Consumer Health News Tags: Med Students Commentary Source Type: news

Testing and Treating Latent TB Cost-effective for Some Groups Testing and Treating Latent TB Cost-effective for Some Groups
Testing and treatment for latent tuberculosis infection (LTBI) in U.S. residents born outside the country is cost-effective, according to simulation modeling.Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 19, 2017 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

South Africa:TB Hospital a Pillar of Hope to Besieged Matatiele
[CAJ News] Matatiele -MATATIELE in the Eastern Cape is synonymous with demarcation deadlocks of the past decade and recent service delivery protests but will soon be mentioned in the same breath with a multimillion Rand, world-class facility to treat rampant tuberculosis. Valued at more than R436 million, the Khotsong TB Hospital has become a pillar of hope for communities residing in and around the municipality with a population of over 12 million. Furthermore, the project has set aside over R94 million in construction work fo (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 17, 2017 Category: African Health Source Type: news

'Mystery clients' reveal weaknesses of tuberculosis care in rural China
(PLOS) Many health care providers in China -- especially those at village clinics and township health centers -- fail to correctly manage tuberculosis (TB) cases, according to a study involving standardized patients published this week in PLOS Medicine by Sean Sylvia of the University of North Carolina at Chapel Hill, USA, Chengchao Zhou of Shangdong University, China, and colleagues at the World Bank, McGill University, Stanford University and other institutions in China. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 17, 2017 Category: Infectious Diseases Source Type: news

Namibia:Multi-Drug Resistant TB Drugs' Side Effects Can Be Controlled
[New Era] Windhoek -A recent study titled 'Optimizing the safety of multidrug-resistant (MDR) tuberculosis therapy in Namibia', by Evans Sagwa, showed that side effects occur frequently in patients treated with current second-line anti-TB drugs. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - October 16, 2017 Category: Infectious Diseases Source Type: news

South Africa:New Tuberculosis Drugs Are More Effective and May Be Less Toxic. Why Are They Still Unavailable?
[Daily Maverick] The start of 2017 saw concern over a sharp increase in the rise of drug- resistant TB in South Africa. TB is killing millions each year. Last week, M édecins Sans Frontières published promising early data on the use of two new TB drugs, delamanid and bedaquiline, among patients living with drug-resistant TB in Khayelitsha, Cape Town. But availability remains the biggest concern. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 16, 2017 Category: African Health Source Type: news

Neutrons observe vitamin B6-dependent enzyme activity useful for drug development
(DOE/Oak Ridge National Laboratory) Scientists at the Department of Energy's Oak Ridge National Laboratory have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs to battle diseases such as drug-resistant tuberculosis, malaria and diabetes. Specifically, the team used neutron crystallography to study the location of hydrogen atoms in aspartate aminotransferase, or AAT, an enzyme vital to the metabolism of certain amino acids. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 16, 2017 Category: International Medicine & Public Health Source Type: news

Global Health: In Early Results, Shorter Treatment for Tuberculosis Proves Effective
A nine-month course of treatment seems to work as well as a longer regimen to cure drug-resistant tuberculosis, a growing threat to global health. (Source: NYT Health)
Source: NYT Health - October 13, 2017 Category: Consumer Health News Authors: DONALD G. McNEIL Jr. Tags: Tuberculosis Antibiotics Clinical Trials World Health Organization Drugs (Pharmaceuticals) Source Type: news

Governments Must Step Up Fight Against Drug-Resistant TB
People with multidrug-resistant tuberculosis need access to newer drugs that could be a lifeline.  Language English (Source: MSF News)
Source: MSF News - October 13, 2017 Category: International Medicine & Public Health Authors: Jess Brown Source Type: news

Governments Must Step Up the Use of Newer Drugs to Fight Multidrug-Resistant TB
Press releaseGovernments Must Step Up the Use of Newer Drugs to Fight Multidrug-Resistant TBOctober 13, 2017Guadalajara, Mexico,  October 13, 2017—People with drug-resistant tuberculosis (DR-TB) are still not receiving two newer tuberculosis  (TB) drugs, bedaquiline and delamanid, which have shown improved cure rates for the disease, said the international medical humanitarian organization Doctors Without Borders/Médecins Sans Frontières (MSF) at the48th Union World Conference on  Lung Health in Guadalajara, Mexico, where the  global TB community is meeting. (Source: MSF News)
Source: MSF News - October 13, 2017 Category: International Medicine & Public Health Authors: Jess Brown Source Type: news

AI algorithm predicts lung disease, adverse events on CT
Recent studies have demonstrated the power of artificial intelligence (AI)...Read more on AuntMinnie.comRelated Reading: AI algorithm speeds up assessment of bone age How to develop deep-learning algorithms for radiology AI can yield patient-specific radiation dose estimates ISCT: The long road to full automation in abdominal CT Can AI accurately diagnose tuberculosis from chest x-rays? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 13, 2017 Category: Radiology Source Type: news

UN and partners launch plan to stop transmission of bovine tuberculosis to humans
Stressing the damaging impact on poor rural communities in Africa and South-East Asia of animal tuberculosis ’ (bovine TB) transmission to humans, United Nations health experts launched the first-ever roadmap to combat the so-called zoonotic TB. (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - October 12, 2017 Category: International Medicine & Public Health Source Type: news

Zimbabwe: Tackling TB Through Music, Dance
[The Herald] Despite his eloquent voice and exuberant theatrics on stage, deep down under, Progress Chipfumo is still smarting from survival scars, vestiges of an ailment onslaught and is now a man on a mission. The determined Afro pop musician, a survivor of the tuberculosis, which nearly put him off the musical scene rails nearly a decade ago is set to launch an ambitious plan whereby he will be spreading awareness of the disease through music. The lingering thoughts about 2008, the year when he was diagnosed with th (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - October 12, 2017 Category: Infectious Diseases Source Type: news

Zimbabwe:Tackling TB Through Music, Dance
[The Herald] Despite his eloquent voice and exuberant theatrics on stage, deep down under, Progress Chipfumo is still smarting from survival scars, vestiges of an ailment onslaught and is now a man on a mission. The determined Afro pop musician, a survivor of the tuberculosis, which nearly put him off the musical scene rails nearly a decade ago is set to launch an ambitious plan whereby he will be spreading awareness of the disease through music. The lingering thoughts about 2008, the year when he was diagnosed with th (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - October 12, 2017 Category: Infectious Diseases Source Type: news

Africa: Global Fund and the Union Deepen Partnership to Fight TB
[Global Fund] Guadalajara, Mexico -The Global Fund to Fight AIDS, Tuberculosis and Malaria and the International Union against Tuberculosis and Lung Disease, also known as The Union, announced a partnership agreement to deepen their shared commitment to end tuberculosis as an epidemic. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - October 12, 2017 Category: Infectious Diseases Source Type: news

Africa:Global Fund and the Union Deepen Partnership to Fight TB
[Global Fund] Guadalajara, Mexico -The Global Fund to Fight AIDS, Tuberculosis and Malaria and the International Union against Tuberculosis and Lung Disease, also known as The Union, announced a partnership agreement to deepen their shared commitment to end tuberculosis as an epidemic. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - October 12, 2017 Category: Infectious Diseases Source Type: news

Researchers find mechanism involved in novel drug design with potential to treat tuberculosis
(Instituto de Medicina Molecular) Portuguese researchers successfully used a pioneer method to chemically modify a protein's components with potential medical applications and an impact in the fight against tuberculosis. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 12, 2017 Category: Infectious Diseases Source Type: news

Timpiyan, Kenya - Zoonotic TB survivor
My name is Timpiyan and I am a zoonotic tuberculosis (TB) survivor. I come from the Kajiado County in Kenya, and I am originally from a Maasai tribe. Since 2016 I have been a member of the World Health Organization (WHO) Civil Society Task Force on TB. In 2011, I realized that something was wrong with my health when I started losing weight while my stomach was constantly swollen. I had a whole body scan at the hospital in Nairobi and the doctors told me that they saw a big mass in my upper abdomen which had to be removed. It turned out it was pus, and when I woke up after a 7-hour surgery, the doctors told me that I had TB...
Source: WHO Feature Stories - October 12, 2017 Category: International Medicine & Public Health Tags: tuberculosis [subject], tb, tuberculosis [subject], tb, African Region [region], Feature [doctype], Kenya [country] Source Type: news

TB Alliance moves two novel tuberculosis drugs into human trials
(Burness) TBA-7371 and sutezolid entered phase 1 clinical trials, TB Alliance announced today. Both compounds have proceeded through early preclinical development and were granted 'Investigative New Drug' status by the US Food and Drug Administration. The phase 1 clinical trials are presently ongoing. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 10, 2017 Category: Infectious Diseases Source Type: news

HIV: The benefits of prophylaxis of tuberculosis are confirmed
(ANRS) Long-term follow-up in the ANRS TEMPRANO trial confirms that tuberculosis chemoprophylaxis in HIV-infected people is more than ever relevant in resource-limited countries. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - October 9, 2017 Category: International Medicine & Public Health Source Type: news

TGen sequencing test enables precise identification of drug-resistant TB
(The Translational Genomics Research Institute) Two studies led by the Translational Genomics Research Institute (TGen) and the University of California San Francisco (UCSF) document how a new advanced genetic sequencing approach can help thwart the growing worldwide threat posed by drug-resistant mutations of tuberculosis (TB). The threat of TB is increasing in some places as mutant versions of the disease become more and more resistant to current drug treatments. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 9, 2017 Category: Infectious Diseases Source Type: news

Inuit, Ottawa launch task force to fight tuberculosis in the North
The federal government and Inuit have launched a task force to examine the tuberculosis crisis across Inuit Nunangat - communities located in the four Inuit regions in northern coastal Labrador, northern Quebec, the territory of Nunavut and a region of the Northwest Territories. . Among Inuit, the tuberculosis rate in 2015 was more than 270 times higher than that of Canadian-born non-Indigenous people. (Source: CBC | Health)
Source: CBC | Health - October 8, 2017 Category: Consumer Health News Tags: News/Canada/North Source Type: news

Malawi: Uncooperative Miners Hampering TB Fight
[Malawi News Agency] Mzuzu -Health officials in Mzimba have bemoaned that uncooperative small scale miners are hindering efforts in the fight against tuberculosis (TB) as they work without protective wear. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 7, 2017 Category: African Health Source Type: news