Fight Aging! Newsletter, May 8th 2017
This report captures the state of the research community in a nutshell: progress in the sense that ever more scientists are willing to make the treatment of aging the explicit goal of their research, but, unfortunately, there is still a long way to go in improving the nature of that research. It is still near entirely made up of projects that cannot possibly produce a robust and large impact on human life span. The only course of action likely to extend life by decades in the near future is implementation of the SENS vision for rejuvenation therapies - to repair the molecular damage that causes aging. Everything else on the table is some form of tinkering with the operation of metabolism in order to slightly slow down the accumulation of that damage, such as via capturing some of the calorie restriction response or boosting autophagy. In any machinery, repair is a vastly better strategy for improving function and extending working life span, and our biology is no exception. In March 2017, the Second Interventions in Aging Conference was held in Cancun, Mexico. The meeting, similar to the earlier event in 2015, was focused on interventional strategies. One notable difference was that this year's meeting was much more directed toward potential interventions to target human aging. The field has been very successful over the last decade in identifying interventions that extend lifespan and healthspan in animal models such as yeast, flies, worms, mice and, to some extent,...
"I almost died because I didn't call it chest pain," one woman tweeted after surviving a heart attack
Conclusion: The results show the possibility of reverse causality between consumption of sweetened soft drinks and zBMI in the overweight adolescents group. For eutrophic male adolescents, soft drink consumption can potentially increase the chances of having higher zBMI, which reinforces the need for measures to significantly r educe the consumption of this beverage.
Conclusion: There are differences according to gender, and, in general, women accumulate more protective factors and men, more risk factors.
Conclusion: Our findings contributed to the identification of the most vulnerable population groups to unhealthy dietary patterns and to the understanding of the coexistence of different food habit determinants among adolescents.
Conclusion: Overweight is more frequent among adolescents from low-income strata. Besides being an indicator of nutritional status, overweight may indicate social inequality in Brazil.
Conclusion: These findings are important to support policies that aim to achieve the World Health Organization ’ s goal of reducing hypertension by 25% over the next decade.
Men with clinically detected prostate cancer who had a long life expectancy lived for an additional 2.9 years following radical prostatectomy compared with patients who underwent watchful waiting.Medscape Medical News
Conclusion: the social representations of health professionals about terminally ill children and adolescents are associated with the situations being experienced, the strategies developed to deal with these moments in the exercise of the profession, and the consequences that this experience causes in the health professionals.RESUMO Objetivo: compreender as representa ções sociais dos profissionais de saúde sobre a terminalidade infantojuvenil. Métodos: trata-se de um estudo de abordagem qualitativa, do tipo exploratório descritivo, realizado com 10 profissionais de saúde, seleciona...
Thus,'patients with type 2 diabetes who are trying to lose weight should be encouraged to limit alcohol consumption,'says the lead author of a new study.Medscape Medical News
This study aimed to explore the role of VPL in the development of OIH and the effect of EA treatment on OIH in rats. RF was administered to rats via the tail vein for OIH induction. Paw withdrawal threshold (PWT) in response to mechanical stimuli and paw withdrawal latency (PWL) to thermal stimulation were tested in rats for the assessment of mechanical allodynia and thermal hyperalgesia, respectively. Spontaneous neuronal activity and local field potential (LFP) in VPL were recorded in freely moving rats using the in vivo multichannel recording technique. EA at 2 Hz frequency (pulse width 0.6 ms, 1-3 ...
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