Janssen Announces U.S. FDA Approval of CABENUVA (rilpivirine and cabotegravir), the First Long-Acting Regimen for the Treatment of HIV
TITUSVILLE, N.J., January 21, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the U.S. Food and Drug Administration (FDA) has approved CABENUVA (consisting of Janssen’s rilpivirine and ViiV Healthcare’s cabotegravir), the first and only once-monthly, long-acting regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults. The novel regimen was co-developed as part of a collaboration with ViiV Healthcare and builds on Janssen’s 25-year commitment to make HIV history. In the U.S., ViiV Healthcare is the marketing authorization holde...
Source: Johnson and Johnson - January 22, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Study Reveals New Insights into the Link Between Sunlight Exposure and Kidney Damage in Lupus
A new collaborative study from researchers at the Geisel School of Medicine at Dartmouth and the University of Washington and published in the Proceedings of the National Academy of Sciences (PNAS), reveals unexpected insights into how skin exposure to ultraviolet light can worsen clinical symptoms in autoimmune diseases such as lupus. (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - January 21, 2021 Category: Hospital Management Authors: Timothy Dean Tags: News Research kidney lupus ultraviolet light Source Type: news

More Than 200,000 Americans Have Lupus
THURSDAY, Jan. 21, 2021 -- Just over 200,000 Americans have the autoimmune disorder lupus, and minority women are at highest risk, according to a new study. It's the first estimate of how widespread the disease is in the United States. The number... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 21, 2021 Category: General Medicine Source Type: news

Study finds especially high rates of lupus in certain racial/ethnic groups
(Wiley) The US prevalence of the autoimmune disease lupus is 72.8 cases per 100,000 individuals, according to an analysis of population-based registries. The analysis, which is published in Arthritis& Rheumatology, found that the rate is 9 times higher for females than males (128.7 vs. 14.6 per 100,000), and it's highest among American Indians/Alaska Natives and Black females. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 21, 2021 Category: International Medicine & Public Health Source Type: news

Study reveals new insights into the link between sunlight exposure and kidney damage
(The Geisel School of Medicine at Dartmouth) A new collaborative study from researchers at the Geisel School of Medicine at Dartmouth and the University of Washington and published in the Proceedings of the National Academy of Sciences (PNAS), reveals unexpected insights into how skin exposure to ultraviolet light can worsen clinical symptoms in autoimmune diseases such as lupus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 21, 2021 Category: International Medicine & Public Health Source Type: news

Fatty acid may help combat multiple sclerosis
(Yale University) The abnormal immune system response that causes multiple sclerosis (MS) by attacking and damaging the central nervous system can be triggered by the lack of a specific fatty acid in fat tissue, according to a new Yale study. The finding suggests that dietary change might help treat some people with the autoimmune disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 19, 2021 Category: International Medicine & Public Health Source Type: news

In lab study, nanoparticle shows promising results for treating severe allergies
For about 1 in 13 children in the U.S., usually harmless foodstuffs such as milk, eggs and peanuts can send the body ’s natural defenses into overdrive.Symptoms of food allergies can vary widely, but at worst, a systemwide allergic response can lead to anaphylaxis, a life-threatening condition characterized by a sudden drop in blood pressure and difficulty breathing.Although there are now some preventive measures for food-induced anaphylaxis, there are not yet any long-lasting solutions — treatments capable of locking the immune system into a state of tolerance, so that it doesn’t respond to allergens.Now...
Source: UCLA Newsroom: Health Sciences - January 14, 2021 Category: Universities & Medical Training Source Type: news

Aberrant type 1 immunity drives susceptibility to mucosal fungal infections
Human monogenic disorders have revealed the critical contribution of type 17 responses in mucosal fungal surveillance. We unexpectedly found that in certain settings, enhanced type 1 immunity rather than defective type 17 responses can promote mucosal fungal infection susceptibility. Notably, in mice and humans with AIRE deficiency, an autoimmune disease characterized by selective susceptibility to mucosal but not systemic fungal infection, mucosal type 17 responses are intact while type 1 responses are exacerbated. These responses promote aberrant interferon- (IFN-)– and signal transducer and activator of transcript...
Source: ScienceNOW - January 14, 2021 Category: Science Authors: Break, T. J., Oikonomou, V., Dutzan, N., Desai, J. V., Swidergall, M., Freiwald, T., Chauss, D., Harrison, O. J., Alejo, J., Williams, D. W., Pittaluga, S., Lee, C.-C. R., Bouladoux, N., Swamydas, M., Hoffman, K. W., Greenwell-Wild, T., Bruno, V. M., Rose Tags: Immunology, Medicine, Diseases, Online Only r-articles Source Type: news

Scientists discover key enzyme responsible for skin blistering in the elderly
(University of British Columbia) The Granzyme B (GzmB) enzyme, which accumulates in certain tissues as we age, has been identified as a driver of itchy and sometimes life-threatening autoimmune conditions known as pemphigoid diseases (PDs), which cause blistering and skin erosion below the skin's surface. New research led by University of British Columbia (UBC) and Vancouver Coastal Health Research Institute (VCHRI) scientists has found that a gel containing a specific and potent inhibitor of GzmB activity, VTI-1002, resulted in significant improvements on skin affected by PDs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 12, 2021 Category: International Medicine & Public Health Source Type: news

Study reveals new details about how bacterial toxins cause life-threatening colitis
FINDINGSResearch led by scientists from UCLA and Harvard University has uncovered details about how the bacterium Clostridioides difficile causes excessive inflammation in the gut that can lead to potentially deadly colitis. Studying C. difficile toxin A, one of two toxins released by the bacterium, the researchers produced two key findings.They pinpointed which part of the toxic protein can permeate cell membranes to gain entry to cellular structures called endosomes, demonstrating that even fragments of the protein that contain that key segment are capable of accessing endosomes.In addition, they revealed how the toxin m...
Source: UCLA Newsroom: Health Sciences - January 8, 2021 Category: Universities & Medical Training Source Type: news

COVID-19 outcomes for patients on immunosuppressive drugs on par with non- immunosuppressed patients
(Johns Hopkins University Bloomberg School of Public Health) People taking immunosuppressive drugs to prevent organ transplant rejection or to treat inflammatory or autoimmune diseases do not fare worse than others on average when they are hospitalized with COVID-19. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 7, 2021 Category: International Medicine & Public Health Source Type: news

A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
The ability to control autoreactive T cells without inducing systemic immune suppression is the major goal for treatment of autoimmune diseases. The key challenge is the safe and efficient delivery of pharmaceutically well-defined antigens in a noninflammatory context. Here, we show that systemic delivery of nanoparticle-formulated 1 methylpseudouridine-modified messenger RNA (m1 mRNA) coding for disease-related autoantigens results in antigen presentation on splenic CD11c+ antigen-presenting cells in the absence of costimulatory signals. In several mouse models of multiple sclerosis, the disease is suppressed by treatment...
Source: ScienceNOW - January 7, 2021 Category: Science Authors: Krienke, C., Kolb, L., Diken, E., Streuber, M., Kirchhoff, S., Bukur, T., Akilli-Öztürk, O., Kranz, L. M., Berger, H., Petschenka, J., Diken, M., Kreiter, S., Yogev, N., Waisman, A., Kariko, K., Türeci, O., Sahin, U. Tags: Immunology, Medicine, Diseases r-articles Source Type: news

Virginia Beach (VA) EMS Helps to Administer COVID-19 Vaccines
Alissa Skelton The Virginian-Pilot (MCT) Masked drivers pulled into a Virginia Beach ambulance bay and rolled down their windows to receive the Moderna vaccine in their left arms on Tuesday. Hannah McConnell, 26, who works for Virginia Beach Neurology, was one of the health care workers given the opportunity to get the vaccine. Erol Aydar, a senior paramedic, prepped the vaccine at a table next to her car and approached her window to explain the procedure and administer the shot. “Finally,” McConnell said after Aydar put the vaccine in her arm. “It was easy. I don&rsq...
Source: JEMS Patient Care - January 6, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed EMS Medicine Virginia Source Type: news

Virginia Beach (VA) EMS Helps to Administer COVID-19 Vaccines
Alissa Skelton The Virginian-Pilot (MCT) Masked drivers pulled into a Virginia Beach ambulance bay and rolled down their windows to receive the Moderna vaccine in their left arms on Tuesday. Hannah McConnell, 26, who works for Virginia Beach Neurology, was one of the health care workers given the opportunity to get the vaccine. Erol Aydar, a senior paramedic, prepped the vaccine at a table next to her car and approached her window to explain the procedure and administer the shot. “Finally,” McConnell said after Aydar put the vaccine in her arm. “It was easy. I don&rsq...
Source: JEMS Administration and Leadership - January 6, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed EMS Medicine Virginia Source Type: news

Virginia Beach (VA) EMS Helps to Administer COVID-19 Vaccines
Alissa Skelton The Virginian-Pilot (MCT) Masked drivers pulled into a Virginia Beach ambulance bay and rolled down their windows to receive the Moderna vaccine in their left arms on Tuesday. Hannah McConnell, 26, who works for Virginia Beach Neurology, was one of the health care workers given the opportunity to get the vaccine. Erol Aydar, a senior paramedic, prepped the vaccine at a table next to her car and approached her window to explain the procedure and administer the shot. “Finally,” McConnell said after Aydar put the vaccine in her arm. “It was easy. I don&rsq...
Source: JEMS Latest News - January 6, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed EMS Medicine Virginia Source Type: news

Virginia Beach (VA) EMS Helps to Administer COVID-19 Vaccines
Alissa Skelton The Virginian-Pilot (MCT) Masked drivers pulled into a Virginia Beach ambulance bay and rolled down their windows to receive the Moderna vaccine in their left arms on Tuesday. Hannah McConnell, 26, who works for Virginia Beach Neurology, was one of the health care workers given the opportunity to get the vaccine. Erol Aydar, a senior paramedic, prepped the vaccine at a table next to her car and approached her window to explain the procedure and administer the shot. “Finally,” McConnell said after Aydar put the vaccine in her arm. “It was easy. I don&rsq...
Source: JEMS: Journal of Emergency Medical Services News - January 6, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed EMS Medicine Virginia Source Type: news

Virginia Beach (VA) EMS Helps to Administer COVID-19 Vaccines
Alissa Skelton The Virginian-Pilot (MCT) Masked drivers pulled into a Virginia Beach ambulance bay and rolled down their windows to receive the Moderna vaccine in their left arms on Tuesday. Hannah McConnell, 26, who works for Virginia Beach Neurology, was one of the health care workers given the opportunity to get the vaccine. Erol Aydar, a senior paramedic, prepped the vaccine at a table next to her car and approached her window to explain the procedure and administer the shot. “Finally,” McConnell said after Aydar put the vaccine in her arm. “It was easy. I don&rsq...
Source: JEMS Operations - January 6, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed EMS Medicine Virginia Source Type: news

Virginia Beach (VA) EMS Helps to Administer COVID-19 Vaccines
Alissa Skelton The Virginian-Pilot (MCT) Masked drivers pulled into a Virginia Beach ambulance bay and rolled down their windows to receive the Moderna vaccine in their left arms on Tuesday. Hannah McConnell, 26, who works for Virginia Beach Neurology, was one of the health care workers given the opportunity to get the vaccine. Erol Aydar, a senior paramedic, prepped the vaccine at a table next to her car and approached her window to explain the procedure and administer the shot. “Finally,” McConnell said after Aydar put the vaccine in her arm. “It was easy. I don&rsq...
Source: JEMS Special Topics - January 6, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed EMS Medicine Virginia Source Type: news

New research finds ginger counters certain autoimmune diseases in mice
(Michigan Medicine - University of Michigan) The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 6, 2021 Category: Biology Source Type: news

A new approach to study autoimmune diseases
This study, " Gene expression signatures of target tissues in type 1 diabetes, lupus erythematosus, multiple sclerosis and rheumatoid arthritis, " is featured in the Jan. 6, 2021, edition ofScience Advances. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 6, 2021 Category: International Medicine & Public Health Source Type: news

Capitol Hill briefing — autoimmune disease and environmental exposure
A congressional briefing focused on the connections between autoimmune disease and genetic and environmental factors. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - January 6, 2021 Category: Environmental Health Source Type: news

Study Finds AD Significantly Associated With Autoimmune Diseases Study Finds AD Significantly Associated With Autoimmune Diseases
AD is associated with other atopic conditions and there is evidence it is associated with some some cancers, cardiovascular disease, and neuropsychiatric disorders, according to Lina U. Ivert, MD.Medscape Medical News (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - January 5, 2021 Category: Dermatology Tags: Dermatology News Source Type: news

CDC Issues COVID-19 Vaccine Guidance for Underlying Conditions CDC Issues COVID-19 Vaccine Guidance for Underlying Conditions
The guidance had specific information for people with HIV, weakened immune systems, and autoimmune conditions such as Guillain-Barre syndrome and Bell's palsy who are planning to get the vaccine.WebMD Health News (Source: Medscape Pulmonary Medicine Headlines)
Source: Medscape Pulmonary Medicine Headlines - December 28, 2020 Category: Respiratory Medicine Tags: Infectious Diseases News Source Type: news

'I just want a life': Loneliest patient spends six months alone with a deadly disease
Khaidir Abu Jalil was diagnosed with a rare, deadly, autoimmune disease at the start of the pandemic. He knows nobody and is about to be... (Source: Reuters: Health)
Source: Reuters: Health - December 23, 2020 Category: Consumer Health News Source Type: news

Atopic Dermatitis Tied to Autoimmune Diseases
MONDAY, Dec. 21, 2020 -- Autoimmune disease comorbidity among adults with atopic dermatitis is common, according to a study recently published the British Journal of Dermatology. Lina U. Ivert, from the Karolinska Institutet in Stockholm, and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 21, 2020 Category: Pharmaceuticals Source Type: news

UC: Can the Autoimmune Protocol Diet Help?
Can a diet called the autoimmune protocol, or AIP, improve your ulcerative colitis? Possibly. Some people say elimination diets, like AIP and others, put their disease in remission. (Source: WebMD Health)
Source: WebMD Health - December 21, 2020 Category: Consumer Health News Source Type: news

COVID-19 vaccines contain deadly epitopes that cause autoimmune disease
(Natural News) During a recent Pennsylvania Medical Freedom Press Conference, Dr. James Lyons-Weiler powerfully chastised Big Pharma for unleashing deadly Wuhan coronavirus (COVID-19) vaccines that contain ingredients known to cause autoimmune disease. Rather than take Dr. Lyons-Weiler’s advice urging them to remove what are known as epitopes from their jab formulas, vaccine companies instead rushed... (Source: NaturalNews.com)
Source: NaturalNews.com - December 16, 2020 Category: Consumer Health News Source Type: news

RA: What Doctors Might Not Tell You
What is life really like with rheumatoid arthritis? When you’re diagnosed with RA, your doctor may talk with you about joint pain and medications to treat it. But later, RA can cause fatigue, morning stiffness, or anxiety, and put you at risk for other autoimmune diseases too. Find out what to expect and how to cope. (Source: WebMD Health)
Source: WebMD Health - December 11, 2020 Category: Consumer Health News Source Type: news

Deaths Up During Pandemic for Those With Rare Autoimmune Disorders
THURSDAY, Dec. 10, 2020 -- Individuals with rare autoimmune rheumatic diseases (RAIRD) have a more prominently increased risk for all-cause death during COVID-19 compared with the general population, according to a study published online Dec. 4 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 10, 2020 Category: Pharmaceuticals Source Type: news

New connections: Restoring immune balance
New targets to expand regulatory T cell populations may be therapeutic for autoimmune and inflammatory diseases. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - December 8, 2020 Category: Science Authors: Ferrarelli, L. K. Tags: STKE Editors ' Choice Source Type: news

Study identifies links between atopic dermatitis and autoimmune diseases
(Wiley) In a recent study published in the British Journal of Dermatology, individuals with atopic dermatitis, or eczema, were more likely to also have various autoimmune diseases, especially those involving the skin, the gastrointestinal tract, or the connective tissue. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 7, 2020 Category: International Medicine & Public Health Source Type: news

Autoimmune connective tissue disease following carbon monoxide poisoning: a nationwide population-based cohort study - Huang CC, Ho CH, Chen YC, Hsu CC, Lin HJ, Wang JJ, Guo HR.
BACKGROUND: In addition to hypoxia, oxidative stress and inflammation due to carbon monoxide (CO) poisoning cause adverse health effects. These mechanisms are related to the occurrence of autoimmune connective tissue disease, but studies on the associat... (Source: SafetyLit)
Source: SafetyLit - December 5, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

NIDCR's Winter 2020 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Winter 2020 E-Newsletter In this issue: NIDCR News Funding Opportunities NIH/HHS News Funding Notices Science Advances Subscribe to NICDR News Grantee News   NIDCR News NIDCR Welcomes New Director Rena D’Souza Rena N. D’Souza, DDS, MS, PhD, was sworn in as the director of NIDCR by NIH Director Francis S. Collins, MD, PhD, on October 13. Prior to joining NIH, Dr. D’Souza was the assistant vice president for academic affairs and education for health s...
Source: NIDCR Science News - December 4, 2020 Category: Dentistry Source Type: news

Genetically engineered T cells could lead to therapies for autoimmune diseases
(University of Arizona Health Sciences) University of Arizona Health Sciences immunobiologists have created a five-module chimeric antigen receptor T cell that is showing early potential to fight Type 1 diabetes. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 3, 2020 Category: Cancer & Oncology Source Type: news

The impact of Neandertal DNA on human health
(Estonian Research Council) A researcher at the University of Tartu described new associations between Neandertal DNA and autoimmune diseases, prostate cancer and type 2 diabetes. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 3, 2020 Category: Biology Source Type: news

People with rare autoimmune diseases at increased risk of dying during COVID-19 pandemic
(University of Nottingham) A new study, led by experts from the University of Nottingham, has shown that people with rare autoimmune rheumatic diseases are at a greater risk of dying at a younger age during the COVID-19 pandemic. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 3, 2020 Category: Infectious Diseases Source Type: news

FDA approves Xolair ® (omalizumab) for adults with nasal polyps
             Basel, 01 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application (sBLA) for Xolair® (omalizumab) for the add-on maintenance treatment of nasal polyps in adult patients 18 years of age and older with inadequate response to nasal corticosteroids.1 Nasal polyps can lead to a loss of smell and nasal congestion, and frequently co-occur with other respiratory conditions, such as allergies and asthma. With this ap...
Source: Roche Media News - December 1, 2020 Category: Pharmaceuticals Source Type: news

FDA approves Xolair ® (omalizumab) for adults with nasal polyps
             Basel, 01 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application (sBLA) for Xolair® (omalizumab) for the add-on maintenance treatment of nasal polyps in adult patients 18 years of age and older with inadequate response to nasal corticosteroids.1 Nasal polyps can lead to a loss of smell and nasal congestion, and frequently co-occur with other respiratory conditions, such as allergies and asthma. With this ap...
Source: Roche Investor Update - December 1, 2020 Category: Pharmaceuticals Source Type: news

Does an Autoimmune Disorder Affect My Covid-19 Risks?
Patients with conditions like lupus and rheumatoid arthritis, who may take immune suppressing drugs, do not appear to be at greatly increased risk from coronavirus. (Source: NYT Health)
Source: NYT Health - November 18, 2020 Category: Consumer Health News Authors: Mikkael A. Sekeres, M.D. Tags: Coronavirus (2019-nCoV) Autoimmune Diseases Immune System Rheumatoid Arthritis Lupus Erythematosus Hygiene and Cleanliness Content Type: Service Source Type: news

Study explores sleep apnea, autoimmune disease link
(University of Georgia) New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 17, 2020 Category: International Medicine & Public Health Source Type: news

Akers Biosciences' stock soars 29% on merger deal
The combined company will be based in Baltimore and focus on developing treatments for autoimmune and age-related diseases. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 13, 2020 Category: Biotechnology Authors: John George Source Type: news

COVID-19 Risks in Rheumatic Disease Remain Unclear COVID-19 Risks in Rheumatic Disease Remain Unclear
Among people with COVID-19, those with systemic autoimmune rheumatic diseases had an elevated 30-day risk of hospitalization, ICU admission, need for mechanical ventilation, and acute kidney injury.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - November 8, 2020 Category: Internal Medicine Tags: Rheumatology News Source Type: news

Pregnancy Can Be Safe With Interstitial Lung Disease Pregnancy Can Be Safe With Interstitial Lung Disease
Often women with ILD related to an autoimmune disease are advised to avoid conception or terminate their pregnancy. But the largest study to date on the subject draws more optimistic conclusions.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 8, 2020 Category: Consumer Health News Tags: Rheumatology News Source Type: news

COVID-19-Related HCQ Shortages Affected Rheum Patients Worldwide COVID-19-Related HCQ Shortages Affected Rheum Patients Worldwide
Supplies were diverted for COVID when hydroxychloroquine was hyped, without good evidence, as a treatment. In some parts of the world more than 1 in 4 with autoimmune diseases could not get medicines.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - November 6, 2020 Category: Drugs & Pharmacology Tags: Rheumatology News Source Type: news

Janssen Headlines American Society of Hematology Annual Meeting With More Than 35 Presentations Highlighting Deep, Diverse Oncology Pipeline and Portfolio
RARITAN, N.J., November 5, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today more than 35 company-sponsored studies, including 10 oral presentations, will be featured at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition taking place virtually December 5-8, 2020.In multiple myeloma, highlights include Phase 1b/2 results for the B-cell maturation antigen (BCMA)-targeted chimeric antigen receptor T-cell (CAR-T) therapy ciltacabtagene autoleucel (cilta-cel); new and updated data for the anti-CD38 monoclonal antibody DARZALEX® (daratumumab) and the subcutane...
Source: Johnson and Johnson - November 5, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Scientists Have Uncovered the Likely Cause of a Serious COVID-19 Symptom: Blood Clotting
One of the more surprising symptoms of COVID-19 has been the blood clots that many patients, including younger ones, have experienced with the infection. The clots have in some cases led to dangerous blockages in the lungs, caused strokes and even death, even in people without a history of circulatory conditions. In a paper published in Science earlier this week, researchers provide a glimpse into what may be driving the clots triggered by COVID-19 infection. The group found that a specific set of antibodies known as autoantibodies—which are rogue versions of cells meant to defend the body from pathogens, but instead...
Source: TIME: Health - November 5, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

NIDCR Science News - November 2020
Having trouble viewing this email? View it as a Web page. A monthly update of NIDCR-supported science advances, as reported by grantee institutions and NIH. Scientists Drill Down on Bacteria-Fighting Fillings Artificial intelligence aids design of antimicrobial dental adhesive NIDCR • October 20, 2020 New Insights into Autoimmune DiseaseUniversity of Pennsylvania • October 26, 2020 Pituitary Puzzle Gets a New Piece, Revising Evolutionary HistoryUniversity of S...
Source: NIDCR Science News - November 2, 2020 Category: Dentistry Source Type: news

Athos Therapeutics Announces Appointment of Chief Business Officer
LOS ANGELES, Nov. 2, 2020 -- (Healthcare Sales & Marketing Network) -- Athos Therapeutics Inc., a late pre-clinical stage biotechnology company pioneering the development of first-in-class precision therapeutics for patients with autoimmune diseases and c... Biopharmaceuticals, Personnel Athos Therapeutics, Ulcerative Colitis, Crohn's Disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 2, 2020 Category: Pharmaceuticals Source Type: news

UCLA researchers create millions of diverse T cells from a single blood stem cell
Researchers at the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a way to make mouse thymus organoids  that can be grown in the lab, each one about 2 millimeters in size.The advance will enable them to follow the precise path by which T cells — critical players in the immune system — are formed from blood stem cells inside the thymus, a small gland in the middle of the chest.In 2017, UCLA ’sDr. Gay Crooks and her colleaguesdevelopeda lab-grown human thymus organoid— a cluster of cells that mimics the thymus. Using the organoid, her...
Source: UCLA Newsroom: Health Sciences - October 30, 2020 Category: Universities & Medical Training Source Type: news

Coronavirus: Destructive 'autoantibodies' develop in some survivors
So-called 'autoantibodies' are similar to the autoimmune responses seen in diseases like lupus, some forms of hepatitis and rheumatoid arthritis, Emory University research suggests. (Source: the Mail online | Health)
Source: the Mail online | Health - October 29, 2020 Category: Consumer Health News Source Type: news