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M&As this week: Epiva Biosciences, Ningbo Medical System Biotechnology, Martindale Pharmaceuticals
Epiva Biosciences has merged with Evelo Biosciences INC to create an immune-microbiome company for the development of therapeutics for cancer, autoimmune and inflammatory diseases. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - July 14, 2016 Category: Pharmaceuticals Source Type: news

M & As this week: Epiva Biosciences, Nichi-iko Pharma, Cell Medica
Immunobiotic therapeutics developer Epiva Biosciences has merged with immune-microbiome company Evelo Biosciences to develop new therapeutics for cancer, autoimmune and inflammatory diseases. (Source: Drug Development Technology)
Source: Drug Development Technology - July 14, 2016 Category: Pharmaceuticals Source Type: news

Zika epidemic has peaked and may run its course within 18 months, say experts
Researchers have created a model of the virus, currently circulating in more than 35 countries in the Americas, to explore how the epidemic will play out The Zika virus epidemic in Latin America is likely to run its course within the next 18 months, according to a study by researchers in the UK and US.Zika is currently circulating in more than 35 countries in the Americas and is primarily spread by mosquitoes. It is believed to cause the birth defect microcephaly, that results in babies being born with and unusually small head and possible damage to the brain, as well as the autoimmune disorder Guillain-Barré syndro...
Source: Guardian Unlimited Science - July 14, 2016 Category: Science Authors: Nicola Davis Tags: Zika virus Infectious diseases Science Medical research World news Americas Microbiology Source Type: news

Is Peace Possible?
“Out beyond ideas of wrongdoing and rightdoing, there is a field. I'll meet you there.” –Jalaluddin Rumi Violence and incidents of terrorism on the planet are escalating, making our inquiry into the question Is Peace Possible? timely and deeply compelling. Perhaps the best definition of peace we've ever heard is the one USM's Founder, John-Roger, has given: "Peace is the cessation of against-ness." Now, the way some people deal with definitions is to either agree or disagree with them. And usually if we agree, we decide that the definition is true; whereas if we disagree, it's untrue. This may s...
Source: Healthy Living - The Huffington Post - July 13, 2016 Category: Consumer Health News Source Type: news

Discovery of mechanisms triggering excess antibody production during chronic infection
Some autoimmune diseases and persistent infections are characterized by high levels of antibodies in the blood. But what are the causes of this hypergammaglobulinemia? Medical researchers have successfully identified the mechanisms triggering the phenomenon. For the first time ever, they have established a link between B-cell activation by a protein -- type 1 interferon -- and unusually high antibody levels. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 12, 2016 Category: Science Source Type: news

Nerve Zap Eased Rheumatoid Arthritis in Small Study
TUESDAY, July 12, 2016 -- Electronic stimulation of a nerve running from the brain to the gut may help ease stubborn symptoms of rheumatoid arthritis, preliminary research suggests. The study, of 17 adults with the painful autoimmune disease,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 12, 2016 Category: Journals (General) Source Type: news

Discovery of mechanisms triggering excess antibody production during chronic infection
(Institut national de la recherche scientifique - INRS) Some autoimmune diseases and persistent infections are characterized by high levels of antibodies in the blood. But what are the causes of this hypergammaglobulinemia? A team headed by INRS's Professor Simona Stäger has successfully identified the mechanisms triggering the phenomenon. For the first time ever, she has established a link between B-cell activation by a protein -- type 1 interferon -- and unusually high antibody levels. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 12, 2016 Category: Infectious Diseases Source Type: news

Woman Who Is Paralyzed Is Hiking All Of The Appalachian Trail -- Alone
Hiking 2,000 miles while paralyzed? Sounds impossible. But Stacy Kozel, who lost the function of her legs in 2014, is doing just that by hiking all 2,190 miles of the Appalachian Trail with a pair of high-tech braces.  And she’s embarking on the remarkable journey alone. Spanning thousands of miles of the eastern United States, the Appalachian Trail covers rugged terrain that’s challenging for even the most experienced hikers —only one in four people are able complete the entire trail, according to the Appalachian Trail Conservancy’s website.  Kozel is now halfway through the in...
Source: Healthy Living - The Huffington Post - July 8, 2016 Category: Consumer Health News Source Type: news

[Report] Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
Ideally, therapy for autoimmune diseases should eliminate pathogenic autoimmune cells while sparing protective immunity, but feasible strategies for such an approach have been elusive. Here, we show that in the antibody-mediated autoimmune disease pemphigus vulgaris (PV), autoantigen-based chimeric immunoreceptors can direct T cells to kill autoreactive B lymphocytes through the specificity of the B cell receptor (BCR). We engineered human T cells to express a chimeric autoantibody receptor (CAAR), consisting of the PV autoantigen, desmoglein (Dsg) 3, fused to CD137-CD3ζ signaling domains. Dsg3 CAAR-T cells exhibit sp...
Source: ScienceNOW - July 7, 2016 Category: Science Authors: Christoph T. Ellebrecht Source Type: news

Side Effects May Include: HLH
It was June 2015, and the whole thing had started as hot flashes and a headache at a friend's summer kick-off party. He must've put in some funky ingredients in the punch, I thought to myself after. Or maybe I just drank too much of it? As the days went on the flashes turned into out-of-this-world, 104-105 degree fevers, followed by bed-drenching sweats, then full-on teeth-chattering shivers. I felt like a lobster reaching full boil, only to be transferred to a cryogenic chamber. This went on for almost two weeks. I dreaded the nights the most, when the fevers were at their worst. I couldn't sleep. I went to the emergency...
Source: Healthy Living - The Huffington Post - July 6, 2016 Category: Consumer Health News Source Type: news

Could the gut microbiome be a new therapeutic target for multiple sclerosis?
(Mary Ann Liebert, Inc./Genetic Engineering News) An increasing number of clinical studies are pointing to a link between the autoimmune disease multiple sclerosis (MS) and the composition of microbes in the human gut, sparking new research on the gut microbiome as a potential target for MS treatment and prevention. A comprehensive review article examining the proposed role of gut bacteria and the viruses that infect them in the development and progression of MS is published in Journal of Interferon & Cytokine Research (JICR). (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 6, 2016 Category: Biology Source Type: news

'Civil war' in immune system can fight disease
The immune system can be trained to attack itself to reverse a devastating autoimmune disease, in animals. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - June 30, 2016 Category: Consumer Health News Source Type: news

Biosimilar drugs are priced too high and do little to improve accessibility: Doctors
Biosimilar drugs are follow-on biologics that have nearly the same efficacy as the original drug and used to treat cancer or autoimmune diseases like rheumatoid arthritis. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - June 30, 2016 Category: Pharmaceuticals Source Type: news

[In Depth] Fighting autoimmunity with immune cells
Autoimmune diseases share a grim similarity with cancer: People's own cells become their enemies. But a study published online in Science reveals a happier parallel, suggesting that a therapy designed to harness the immune system to attack cancer cells may also cull the turncoat immune cells behind certain autoimmune diseases. The approach relies on chimeric antigen receptor T cells, or CAR T cells: immune cells genetically modified to home in on a desired target on cancer cells or—in this case—on rogue B cells, another immune cell type. The new study only gauged the CAR T cells' capabilities in the lab dish an...
Source: ScienceNOW - June 30, 2016 Category: Science Authors: Mitch Leslie Tags: Immunology Source Type: news

Natural metabolite can suppress inflammation
An international research team has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages -- specific immune cells. The substance known as itaconate is released in large quantities by macrophages themselves and according to the scientists, acts as an antioxidant and anti-inflammatory agent. These properties make itaconate promising for the treatment of such pathologies as cardiac ischemia, metabolic disorders and autoimmune diseases which may be associated with excessive inflammation or oxidative stress. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 30, 2016 Category: Science Source Type: news

Treating autoimmune disease without harming normal immunity
With potentially major implications for the future treatment of autoimmunity and related conditions, scientists have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system. They studied an autoimmune disease called pemphigus vulgaris, a condition in which a patient's own immune cells attack a protein called desmoglein-3 that normally adheres skin cells. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 30, 2016 Category: Science Source Type: news

Natural metabolite can suppress inflammation
(ITMO University) An international research team has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages -- specific immune cells. The substance known as itaconate is released in large quantities by macrophages themselves and according to the scientists, acts as an antioxidant and anti-inflammatory agent. These properties make itaconate promising for the treatment of such pathologies as cardiac ischemia, metabolic disorders and autoimmune diseases which may be associated with excessive inflammation or oxidative stress. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 30, 2016 Category: Global & Universal Source Type: news

Treating diseases at their origin
(Hokkaido University) Hokkaido University scientists are getting closer to understanding the function of a protein involved in vital cellular processes. This may lead to the discovery of drugs that can treat some cancers and autoimmune disorders. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 30, 2016 Category: Cancer & Oncology Source Type: news

Researchers discover potential genetic trigger of autoimmune disease
Researchers have uncovered a potential genetic trigger of systemic autoimmune disease. The study discovered virus-like elements within the human genome linked to the development of two autoimmune diseases: lupus and Sjogren's syndrome. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 27, 2016 Category: Science Source Type: news

New cancer immunotherapy drugs linked to arthritis in some patients
Case reports on 13 cancer patients suggest that a small number of cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at some higher-than-normal risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a preliminary study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 24, 2016 Category: Science Source Type: news

New cancer immunotherapy drugs linked to arthritis in some patients
(Johns Hopkins Medicine) Case reports on 13 cancer patients suggest that a small number of cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at some higher-than-normal risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a preliminary study by Johns Hopkins Medicine researchers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 23, 2016 Category: Cancer & Oncology Source Type: news

Diabetes 'more frequent in children with juvenile inflammatory arthritis'
This study backs up recent findings that diabetes is more common in people with rheumatoid arthritis than the general population; however, the reasons for this are not yet well understood. There is a growing appreciation of the links between different autoimmune diseases, and further research will be important to fully understand the relationship between juvenile inflammatory arthritis and diabetes - an approach that may lead to new treatments for both conditions." (Source: Arthritis Research UK)
Source: Arthritis Research UK - June 16, 2016 Category: Rheumatology Source Type: news

Seattle biotech Alpine Immune Sciences lands $48M in Series A funding
Seattle's Alpine Immune Sciences has landed $48 million in Series A funding, an amount that the preclinical company expects to get it through clinical trials of its cancer and autoimmune disease drugs. OrbiMed Advisors, a medical and health care investment firm with offices in San Francisco and New York, led the round. Also taking part were Frazier Healthcare Partners and Alpine BioVentures, the investment company that created Alpine Immune Sciences, or AIS. Mitch Gold, a managing partner at Alpine… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - June 13, 2016 Category: Pharmaceuticals Authors: Rachel Nielsen Source Type: news

Seattle biotech Alpine Immune Sciences lands $48M in Series A funding
Seattle's Alpine Immune Sciences has landed $48 million in Series A funding, an amount that the preclinical company expects to get it through clinical trials of its cancer and autoimmune disease drugs. OrbiMed Advisors, a medical and health care investment firm with offices in San Francisco and New York, led the round. Also taking part were Frazier Healthcare Partners and Alpine BioVentures, the investment company that created Alpine Immune Sciences, or AIS. Mitch Gold, a managing partner at Alpine… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - June 13, 2016 Category: Biotechnology Authors: Rachel Nielsen Source Type: news

Medical News Today: Novel blood test could diagnose diseases with no known antigens
Researchers have created a blood test that could one day lead to the detection of cancer, autoimmune diseases, and other conditions with no known antigens. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 13, 2016 Category: Consumer Health News Tags: Medical Devices / Diagnostics Source Type: news

Cancer drugs may be useful for autoimmune diseases, study says
Stephen FellerLONDON, June 10 (UPI) -- A cancer drug reduced the impact of an incurable autoimmune condition, which researchers think may be applicable to other immune system disorders as well. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 11, 2016 Category: Consumer Health News Source Type: news

The non-hospital: Putting patients at the center of care
For Melissa Hicks, it’s not the constant pain, the fatigue and the host of other symptoms that come with her autoimmune disease that make her sick. “What makes me feel really sick is all the work I have to do because I’m a patient,” she said. “Being sick became another full-time job. … When you’re sick, you can’t do two full-time jobs.” Burdens of the current health care environment       Melissa Hicks shares her perspective as a patient with a chronic disease. Hicks, who suffers from Sjogr...
Source: AMA Wire - June 10, 2016 Category: Journals (General) Authors: Troy Parks Source Type: news

Risky stem cell treatment 'halts progress of multiple sclerosis'
Conclusion This early-stage trial aimed to look at a new treatment approach for MS, involving aggressive chemotherapy followed by haematopoietic stem cell transplant (HSCT). Researchers then assessed whether this had an impact on clinical relapse and disability. The study suggests that eliminating an individual's existing "faulty" immune system, and rebuilding it using stem cells, may slow down or completely halt the progression of MS, resulting in an improvement in disability status. Although the study's findings suggest this could be a potential treatment in the future, the researchers say caution is necessar...
Source: NHS News Feed - June 10, 2016 Category: Consumer Health News Tags: Genetics/stem cells Neurology Source Type: news

Cancer drugs could target autoimmune diseases
Drugs currently being trialled in cancer patients have been used to successfully target an autoimmune condition in mice , report researchers. Their study involved giving cancer drugs to mice and inducing uveitis, an incurable autoimmune eye condition responsible for 1 in every 10 cases of visual impairment. The condition was significantly less severe in mice given the cancer drugs. Current treatment options are limited and can cause further visual problems including cataracts. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 9, 2016 Category: Science Source Type: news

Cancer drugs could target autoimmune diseases
(University College London) Drugs currently being trialled in cancer patients have been used to successfully target an autoimmune condition in mice at UCL and King's College London.The study, published in Cell Reports, involved giving cancer drugs to mice and inducing uveitis, an incurable autoimmune eye condition responsible for 1 in every 10 cases of visual impairment. The condition was significantly less severe in mice given the cancer drugs. Current treatment options are limited and can cause further visual problems including cataracts. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 9, 2016 Category: Cancer & Oncology Source Type: news

PRP Therapy: Play Hard, Heal Fast
There’s a way to heal sports injuries that doesn’t involve surgery, months of physical therapy or a dependence on prescription medication. It’s called platelet-rich plasma (PRP) therapy. What Is PRP Therapy? It’s a form of stem cell treatment that uses platelets — colorless blood cells that help your blood clot — to rebuild a damaged tendon or cartilage. It not only relieves the pain, it also jumpstarts the healing process.   That’s because platelets contain hundreds of proteins called “growth factors.” The natural growth factors in PRP can actually regenerate inj...
Source: Al Sears, MD Natural Remedies - June 8, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Intarcia launches Medici drug delivery platform
Intarcia Therapeutics said today it launched its subcutaneous Medici drug delivery system designed for the continuous delivery of medication. The Medici system is comprised of a matchstick-sized osmotic minipump placed just under the skin to deliver medication, a placement system for implantation and stabilization technology designed for proteins, peptides, antibody fragments and other high-potency small molecules. The company said its system will be on display at the American Diabetes Association’s 76th scientific sessions in New Orleans later this month. “Delivering drugs via our new technology has the potent...
Source: Mass Device - June 7, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Business/Financial News Drug Pumps Drug-Device Combinations Intarcia Therapeutics Source Type: news

Child of Narcissists Goes from 'Death-Dealer' to Healer
Charlotte was seven years old when she became in her words the "death dealer" on her family's makeshift farm. At her mother's insistence, the family moved from D.C. to acreage in rural Virginia and embarked on a grand experiment as DIY farmers. Having no experience to guide them, they began collecting animals, from cows and horses and pigs, to sheep and goats, to cats and dogs, and all manner of poultry.    Charlotte's first time watching chicks hatch lurched from delighted wonder to a harsh lesson in the dirty work of farming and a prescribed part in the family script that would shape her life. After o...
Source: Healthy Living - The Huffington Post - June 6, 2016 Category: Consumer Health News Source Type: news

Vedanta Biosciences Closes $50 Million Financing to Advance Microbiome Therapeutics
The funding will accelerate infectious and autoimmune disease programs to the clinic and support scale up of the company’s technology platform CAMBRIDGE, Mass.--(Healthcare Sales & Marketing Network)--Vedanta Biosciences, pioneering the development of a... Biopharmaceuticals, Venture CapitalVedanta Biosciences, microbiome (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 6, 2016 Category: Pharmaceuticals Source Type: news

Arrien Pharmaceuticals begins Phase I trial of ARN-6039 to treat multiple sclerosis
US-based drug-development company Arrien Pharmaceuticals has begun its Phase I clinical trial of ARN-6039 to treat relapse, remitting, and progressive multiple sclerosis (MS), an autoimmune neuroinflammatory demyelinating disease of the central nervo… (Source: Drug Development Technology)
Source: Drug Development Technology - June 5, 2016 Category: Pharmaceuticals Source Type: news

Report: Quarter of lung cancer patients ineligible for immunotherapy
Marilyn MalaraDALLAS, June 4 (UPI) -- Lung cancer patients with autoimmune diseases are not eligible for the latest immunotherapy treatments, University of Texas Southwestern Medical Center found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 4, 2016 Category: Consumer Health News Source Type: news

Up to one-quarter of lung cancer patients ineligible for immunotherapy
A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers has found. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 4, 2016 Category: Science Source Type: news

Cancer treatment untested in many patients with immune problems
(Reuters Health) - - The safety and effectiveness of a new cancer treatment known as immunotherapy is largely unknown in patients with autoimmune diseases, researchers say - and that might account for up to a quarter of individuals with lung cancer. (Source: Reuters: Health)
Source: Reuters: Health - June 4, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

UTSW team find up to one-quarter of lung cancer patients ineligible for immunotherapy
(UT Southwestern Medical Center) A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers at UT Southwestern Medical Center's Harold C. Simmons Comprehensive Cancer Center has found. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 4, 2016 Category: Cancer & Oncology Source Type: news

Human Astroglia and Schwann Cells-BBB Model
Broadening our CapabilitiesAt the core of our solutions are many options for primary human cells. We are especially pleased that we have growing capabilities to provide new cells to researchers studying autoimmune neuro-degenerative diseases like ALS and MS with the addition of:Schwann CellsHuman Schwann Cells (HSwC) are isolated from human spinal nerve. HSwC are cryopreserved at passage one and delivered frozen. Each vial contains>5 x 10^5 cells in 1 ml volume. HSwC are characterized by immunofluorescence with antibodies specific to S100, GFAP, and CD90. HSwC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeas...
Source: Neuromics - June 3, 2016 Category: Neuroscience Tags: ALS Alzheimer ' s Disease astrocyte cultures Blood Brain Barrier Models human Astrocytes human satellite cells MS Multiple Sclerosis Parkinson Source Type: news

The Nicaraguan Diet: Simple, Low-cost, Delicious and Nutritious
The mention of Nicaragua usually conjures thoughts of political instability and poverty but with the growth of tourism this perception is slowly changing. Nicaragua is fast becoming known as a beautiful land of lakes, volcanoes and beaches, however, it does not have a reputation as a culinary destination. Visitors to this Central American country do not expect to consume tasty food; to the contrary, concerns over what to eat may be high on their list. The reality is that the Nicaraguan diet is influenced by Spanish, Creole, and Indigenous cuisine, and although the dishes are simple, they are delicious, and for those wantin...
Source: Healthy Living - The Huffington Post - June 3, 2016 Category: Consumer Health News Source Type: news

Opinion: Educate Your Immune System
Our bodies are confused by this 21st-century world. (Source: NYT Health)
Source: NYT Health - June 3, 2016 Category: Consumer Health News Authors: MOISES VELASQUEZ-MANOFF Tags: Autoimmune Diseases Immune System Genetics and Heredity Diabetes Allergies Microbiology Viruses Source Type: news

Deals this week: BioRap Technologies, Saniona AB, Mylan N.V
BioRap Technologies and Pfizer have entered a co-development agreement to improve the research and development of novel immunomodulators, which will help in introducing new treatment options for chronic autoimmune diseases. (Source: Drug Development Technology)
Source: Drug Development Technology - June 2, 2016 Category: Pharmaceuticals Source Type: news

Young people with lupus 'feel limited by their condition'
Young people with lupus are troubled by a feeling that their condition is limiting their opportunities in life, according to a new study.The Australian research, led by the University of Sydney, formed this conclusion after examining the experiences and perspectives of adolescents and young adults diagnosed with juvenile-onset systemic lupus erythematosus (SLE). The findings could help to inform strategies for improving treatment and health outcomes.The perceived social impact of lupus It is well known that disease activity, organ damage and treatment burden can often have a significant impact on young people with lupus, c...
Source: Arthritis Research UK - June 2, 2016 Category: Rheumatology Source Type: news

MassDevice.com +5 | The top 5 medtech stories for June 2, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Intarcia, Numab log milestones for autoimmune drug-device combo Intarcia Therapeutics and pharmaceuticals maker Numab said today that they’ve logged several milestones in their joint project to develop a drug-device combi...
Source: Mass Device - June 2, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Intarcia, Numab log milestones for autoimmune drug-device combo
Intarcia Therapeutics and pharmaceuticals maker Numab said today that they’ve logged several milestones in their joint project to develop a drug-device combination for treating inflammatory and autoimmune diseases. Wädenswil, Switzerland-based Numab identified a pair of antibody-based compounds for the program, which aims to use the delivery and formulation technology developed by Cambridge, Mass.-based Intarcia. The companies said Intarcia has successfully formulated versions of both the molecule targets identified by Numab. “Achievement of this milestone for Intarcia further confirms the power ...
Source: Mass Device - June 2, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Drug-Device Combinations Intarcia Therapeutics Numab Source Type: news

New free web service for deep study of cell functions
A simple and effective web service has been developed that enables a better understanding of cell functions by identifying links between changes in metabolism and gene expression. New insights gained by means of the service can be applied to develop treatments for autoimmune diseases and cancer, since metabolic regulation plays a major role in such biological processes. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 2, 2016 Category: Science Source Type: news

New free web service for deep study of cell functions
(ITMO University) Scientists from Russia, US, Canada and Germany have developed a simple and effective web service that enables a better understanding of cell functions by identifying links between changes in metabolism and gene expression. New insights gained by means of the service can be applied to develop treatments for autoimmune diseases and cancer, since metabolic regulation plays a major role in such biological processes. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 2, 2016 Category: Biology Source Type: news

New clues found to immune system's misfiring in autoimmune diseases
(Washington University School of Medicine) A person's genetic makeup plays a role in autoimmune diseases that develop when the body is attacked by its own immune system. But little is known about how immune cells are pushed into overdrive. Now, in new research that points to potential therapeutic targets for autoimmune diseases, researchers at Washington University School of Medicine in St. Louis have identified genetic master switches that turn up -- or down -- the activity of specific types of immune cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 2, 2016 Category: Global & Universal Source Type: news

Monthly News Roundup - May 2016
FDA Approves Zinbryta for Multiple Sclerosis Multiple sclerosis, a chronic, inflammatory, autoimmune disease of the central nervous system, has been reported as the leading cause of disability in young adults 20 to 40 years of age. The US Food... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 31, 2016 Category: Pharmaceuticals Source Type: news