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Asbestos Revisited: A New Autoimmune Disease? (CME/CE)
(MedPage Today) -- In the small town of Libby in northwestern Montana, prospectors in 1916 discovered an unusual mineral known as vermiculite that appeared to be resistant to fire after initial exposure to high heat. But the vermiculite was contaminated with asbestos, which killed many residents and now may be contributing to high rates of autoimmunity. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - July 29, 2014 Category: Primary Care Source Type: news

Mysterious esophagus disease is autoimmune after all
(KU Leuven) Achalasia is a rare disease -- it affects one in 100,000 people -- characterized by a loss of nerve cells in the esophageal wall. While its cause remains unknown, a new study by a team of researchers at KU Leuven in Belgium, the University of Bonn in Germany and other European institutions confirms for the first time that achalasia is autoimmune in origin. The study, published on July 6 in Nature Genetics, is an important step towards unraveling the mysterious disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 29, 2014 Category: Biology Source Type: news

Study links shift work to increased risk of diabetes
Conclusion This systematic review finds an association between shift work and diabetes, overall the pooled results found that shift work was associated with a 9% risk of diabetes. The review has strengths in that it has reviewed the global literature and identified a reasonable sample of 12 observational studies including more than 225,000 people. However, there are various important limitations that need to be taken into account before concluding that shift work directly increases the risk of diabetes. Type 1 or type 2? The main point under investigation was whether shift work could be a modifiable risk factor for th...
Source: NHS News Feed - July 25, 2014 Category: Consumer Health News Tags: Diabetes Lifestyle/exercise Source Type: news

Biomedical engineer looks at new applications for novel lupus drug
(University of Houston) Expanding on his work with a new drug that successfully treated lupus in mice, a biomedical engineer at the University of Houston has received a $250,000 grant to expand his research to a new version of the drug in an effort to treat a wider range of autoimmune diseases.The drug that Chandra Mohan and his collaborators at a biopharmaceutical firm are focused on targets B cells, key cells in the immune system that lead to the development of lupus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 24, 2014 Category: Global & Universal Source Type: news

Molecular mechanisms underlying the prevention of autoim-munity by Roquin revealed
(Helmholtz Zentrum München - German Research Center for Environmental Health) Neuherberg, 14 July 2014. Scientists at the Helmholtz Zentrum München, the Ludwig-Maximilians University of Munich and the Technische Universität München have moved an important step closer to understanding molecular mechanisms of autoimmune diseases. They solved the three-dimensional structure of the Roquin protein when bound to messenger ribonucleic acid molecules. The results revealed that there is a much wider range of functionally important Roquin binding partners than previously assumed. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 14, 2014 Category: Biology Source Type: news

Immune/Inflammatory Response and Autism
Autism Spectrum Disorder (ASD) Children and Immune/Inflammatory Response MarkersPersistent chronic inflammation/immune response and oxidative stress are hallmarks of ASD. Like autoimmune diseases, an unbalanced immune system leads to unwanted assaults on healthy tissue. In ASD Children, inflammatory/immune response proteins could cross the Blood-Brain Barrier resulting in ongoing neuro-inflammation. This throws out of balance the natural pruning and repair cycle in the brain and could drive the related behaviors and symptoms of ASD Children.We have been working with ASD children from central Europe residing in areas of hea...
Source: Neuromics - July 11, 2014 Category: Neuroscience Tags: ASD Autism Autism Bio-markers autism spectrum disorder Autistic Autoimmunity IL-2 immune response IL-6 inflammatory response TNF-alpha Source Type: news

Research reveals how key controller protein is switched on
(Biochemical Society) New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated. The discovery answers a key question about one of the most widely-researched proteins in human biology, which has been the subject of tens of thousands of research papers and millions of pounds in research funding. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 10, 2014 Category: Global & Universal Source Type: news

Periodontal Disease in Rheumatoid ArthritisPeriodontal Disease in Rheumatoid Arthritis
A study finding that periodontal disease is associated with RA considers the interesting question of whether the periodontal region, like the joints, are targeted by the autoimmune process. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - July 9, 2014 Category: Rheumatology Tags: Rheumatology Viewpoint Source Type: news

Immune system component found that resists sepsis in mice
Mice lacking a specific component of the immune system are completely resistant to sepsis, a potentially fatal complication of infection, molecular microbiologists report. The discovery suggests that blocking this immune system component may help reduce inflammation in human autoimmune and hyper-inflammatory diseases such as rheumatoid arthritis and Type 2 diabetes. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 9, 2014 Category: Science Source Type: news

Glenmark begins human trials of GBR 830 to treat autoimmune diseases
Glenmark Pharmaceuticals' Swiss subsidiary has announced that its new monoclonal antibody GBR 830 is entering human trials for the treatment of autoimmune diseases. (Source: Drug Development Technology)
Source: Drug Development Technology - July 3, 2014 Category: Pharmaceuticals Source Type: news

Genetics Home Reference: autoimmune Addison disease
http://ghr.nlm.nih.gov/condition/autoimmune-addison-disease (Source: NLM General Announcements)
Source: NLM General Announcements - July 1, 2014 Category: Databases & Libraries Source Type: news

Soothing cells, peaceful protein could hold promise for treating autoimmune uveitis
Researchers at the National Eye Institute (NEI) have found a unique cell type that, in tests on mice, can protect against uveitis—a group of inflammatory diseases that affect the eye and can cause vision loss. (Source: News from NEI)
Source: News from NEI - June 30, 2014 Category: Opthalmology Source Type: news

Xtalks Announces Its July 2014 Webinars
Join Xtalks for this month’s calendar of free webinars, which features insightful discussions about risk-based monitoring (RBM), inflammatory bowel disease, sepsis, autoimmune diseases, biopharma,...(PRWeb June 27, 2014)Read the full story at http://www.prweb.com/releases/2014/06/prweb11966854.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - June 27, 2014 Category: Pharmaceuticals Source Type: news

Depressed? It May Be Celiac Disease
Melanie had been feeling out of sorts for years. No matter how well she slept, she was often fatigued. She had frequent headaches. She had diarrhea so often, she figured it was just how her body worked. She wryly said that she knew where every bathroom in town was located. Although an upbeat person by nature, it was hard for her to be happy when she felt bad so often. Nonetheless, some days were better than others. She was determined not to let how she felt physically get her down. Mel had been going to doctors for years to try to get an answer. Diagnoses included irritable bowel syndrome (IBS), migraine, lactose intoleran...
Source: Psych Central - June 21, 2014 Category: Psychiatry Authors: Marie Hartwell-Walker, Ed.D. Tags: Depression Disorders General Healthy Living Celiac Disease Gluten Gluten-free diet Irritable bowel syndrome National Foundation for Celiac Awareness Source Type: news

T1D Gene May Play Role in Other Diseases (CME/CE)
(MedPage Today) -- New insights into the function of a type 1 diabetes susceptibility gene could lead to novel strategies for treating a host of autoimmune diseases, according to researchers. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - June 20, 2014 Category: Cardiology Source Type: news

Pig whipworm genome may aid to treat autoimmune diseases
The whole-genome sequence of Trichuris suis, a parasitic worm in pig, has been presented by an international team composed of 11 institutions from six countries. Understanding the genetics mechanisms underlying the pig parasite may aid to modify the human immune response that could result in better treatments for autoimmune diseases, including inflammatory bowel disease and multiple sclerosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 20, 2014 Category: Science Source Type: news

The pig whipworm genome may aid to treat autoimmune diseases
(BGI Shenzhen) An international team, composed of 11 institutions from six countries, including BGI, presented the whole-genome sequence of Trichuris suis, a parasitic worm in pig. Understanding the genetics mechanisms underlying the pig parasite may aid to modify the human immune response that could result in better treatments for autoimmune diseases, including inflammatory bowel disease and multiple sclerosis. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 20, 2014 Category: Biology Source Type: news

Teen's struggle with 'old person's' disease: 'I had rheumatoid arthritis at 16'
DISTRESSED Heather Edwards was struggling to walk, kneel down or extend her elbows when she was diagnosed with the autoimmune disease - aged just 16 (Source: Daily Express - Health)
Source: Daily Express - Health - June 19, 2014 Category: Consumer Health News Source Type: news

New method to reduce disease-causing inflammation discovered
An enzyme known as Tumor Progression Locus 2, or Tpl2, plays a key role in directing and regulating several important components of the body's immune system, researchers report. Their discovery may one day lead to new treatments for many common autoimmune diseases. "This is an emerging field," one researcher said. "We have a lot of work to do, but many of our preliminary results are promising." (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 16, 2014 Category: Science Source Type: news

UGA researchers discover new method to reduce disease-causing inflammation
(University of Georgia) Researchers at the University of Georgia report in the Journal of Biological Chemistry that an enzyme known as Tumor Progression Locus 2, or Tpl2, plays a key role in directing and regulating several important components of the body's immune system. Their discovery may one day lead to new treatments for many common autoimmune diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 16, 2014 Category: Global & Universal Source Type: news

Neuromics-Vitro Biopharma in Posrche Cup
Racing to Health and Peak Performance.Neuromics and Vitro Biopharma are proud sponsors of the European Porsche Cup Car driven by our partner, friend and race car driver extraordinaire, Dr. Joe Smarda.Dr. Smarda, an applied immunologist, is our partner in Europe for testing and treating sufferers of autoimmune diseases, sports injuries and autism with Stem Cell Activators. We are also testing these activating agents for the ability to improve the mental acuity and physical performance of healthy individuals.He recently won a race at the Nurbring Ring in Germany. Hmmm, I wonder if the Stem Cell Activators he is taking, ...
Source: Neuromics - June 15, 2014 Category: Neuroscience Tags: Neuromics Porsche Cup Racing regenerative medicine sports medicine stem cell activation stem cell activators Stem Cell Based Therapies Vitro Biopharma Source Type: news

Parasitic worms of pigs could provide new treatments of human diseases
(University of Melbourne) Lead researcher, Dr. Aaron Jex, Faculty of Veterinary Science, said, 'We know that humans infected with the harmless, 'pig whipworm' can have significantly reduced symptoms linked to autoimmune diseases. And now we have the genetic sequence of the worm, it opens the door to future human drug designs and treatment.' (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 15, 2014 Category: Infectious Diseases Source Type: news

Invisible Illness: It’s not easy to combat what you can’t see!
There is a surprising common factor which is shared by a vast range of physical and mental health conditions. Fibromyalgia, anxiety, endometriosis, lupus, endometriosis, pelvic pain and depression may vary in causes and symptoms, but all of them have a deadly weapon in common – invisibility. They are often classed as an invisible illness. These conditions fight their invisible war on two fronts. Firstly, they leave no trace. The majority of these diseases attack the body internally, leaving no external signs which might allow the patient’s suffering to be easily recognised. As well as causing physical pain, inv...
Source: The Hysterectomy Association - June 13, 2014 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health Conditions anxiety autoimmune disease depression endometriosis fibromyalgia invisible illness lupus pelvic pain Source Type: news

Evaluation of the Adverse Effect of Low Concentration of Cadmium on Interleukin-4 Induced Class Switch Recombination in Burkett’s Lymphoma Raji Cell Line
Affinity maturation of B lymphocytes, a process that includes somatic hypermutation and class switch recombination, initiates global DNA rearrangements. The interruption of this process has an adverse effect on human health and results in immunodeficiency and autoimmune disease. Class switch recombination is a fundamental factor of the human adaptive immunity. Evaluation of the class switch recombination efficiency is an important component of laboratory diagnostic of immunotoxic components. Here, we describe a method for testing the efficiency of the class switch recombination. Cultivation of Raji Burkett’s lymphoma...
Source: Springer protocols feed by Immunology - June 10, 2014 Category: Allergy & Immunology Source Type: news

Chemotactic Responses by Macrophages to a Directional Source of a Cytokine Delivered by a Micropipette
Macrophages, which are organized throughout every tissue, represent a key component of the immune system and the recruitment of macrophages to specific sites is important in normal host defense. However, when inappropriately recruited macrophages may damage or destroy healthy tissue; this is seen in several autoimmune diseases such as arthritis. Many cytokines, including CSF-1 and chemokines, are often upregulated in inflamed tissues and can induce the directional migration of macrophages towards the highest concentration of the cytokine in a process called chemotaxis. Chemokines were first described as chemoattractant cyt...
Source: Springer protocols feed by Immunology - June 10, 2014 Category: Allergy & Immunology Source Type: news

Faster, higher, stronger: A protein that enables powerful initial immune response
(The Wistar Institute) A team of Wistar scientists offer evidence that a protein, called Foxp1, is a key controller of our immune system's ability to generate an antibody response. Manipulating this protein's activity, they say, could provide a useful pathway to boosting antibody responses to treat infectious diseases, for example, or suppressing them to treat autoimmune disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 9, 2014 Category: Global & Universal Source Type: news

Stem Cell Therapies without Transplants
Neuromics is partnering with Vitro Biopharma to develop stem cell activating/boosting therapies. Stem cell based therapies represent a shining light of hope for sufferers of chronic or life threatening diseases.  Though, for most, realization of this hope is light years into the future.Dr. Jim Musick, CEO of Vitrobiopharma, recently blogged on the obstacles to approved therapies : "Transplantation of hematopoietic stem cells has been widely used as an approved treatment of leukemia, lymphoma and certain autoimmune conditions for the past fifty years. Other adult stem cells have demonstrated safety and e...
Source: Neuromics - June 7, 2014 Category: Neuroscience Tags: hMCS Human Mesenchymal Stem Cells regenerative medicine stem cell activation stem cell activators stem cell boosters stem cell therapies Source Type: news

Autoimmune Disease & Risk of Gastric Neuroendocrine NeoplasmAutoimmune Disease & Risk of Gastric Neuroendocrine Neoplasm
Are patients with thyroid disease at risk for gastric neuroendocrine neoplasms? Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 5, 2014 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Arena begins Phase Ib trial of APD334 to treat autoimmune diseases
US-based Arena Pharmaceuticals has started dosing patients in an investigational Phase Ib clinical trial of APD334, an oral drug candidate that targets the sphingosine 1-phosphate subtype 1 (S1P1) receptor, to treat a number of autoimmune diseases. (Source: Drug Development Technology)
Source: Drug Development Technology - June 4, 2014 Category: Pharmaceuticals Source Type: news

Marijuana shows potential in treating autoimmune disease
Researchers have discovered a novel pathway through which marijuana's main active constituent, THC, can suppress the body's immune functions. The recent findings show that THC can change critical molecules of epigenome called histones, leading to suppression of inflammation. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 2, 2014 Category: Science Source Type: news

Marijuana shows potential in treating autoimmune disease
(University of South Carolina) A team of University of South Carolina researchers have discovered a novel pathway through which marijuana can suppress the body's immune functions. The recent findings show that marijuana THC can change critical molecules of epigenome called histones, leading to suppression of inflammation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 2, 2014 Category: Global & Universal Source Type: news

A Product For Gaucher Disease And A Plant-Cell For Protein Production – Protalix Biotherapeutics Is On The Rise
Protalix has a unique plant-cell platform for therapeutic protein production and an approved product, Elelyso/Uplyso (taliglucerase alfa), for Gaucher disease. In the company’s pipeline is a chemically modified version of the recombinant alpha-Galactosidase-A protein for Fabry disease (Phase 1/2), an oral glucocerebrosidase (GCD) enzyme replacement therapy for Gaucher disease (Phase 1), an oral anti-TNF (tumor necrosis factor) fusion protein for autoimmune/inflammatory conditions (preclinical), and a human deoxyribonuclease I (DNase I) for cystic fibrosis (preclinical), and other enzyme replacement therapies in early...
Source: Pharmaceutical Online News - May 30, 2014 Category: Pharmaceuticals Source Type: news

FDA allows marketing of first non-invasive test to help in identifying cause of certain kidney disease
Today, the U.S. Food and Drug Administration allowed marketing of the first test that can help determine if a specific type of kidney disease, called membranous glomerulonephritis (MGN), is due to the body’s rejection of its own kidney tissue (autoimmune) or if it is due to another cause (such an infection). (Source: Food and Drug Administration)
Source: Food and Drug Administration - May 29, 2014 Category: American Health Source Type: news

IgG Stable With Rituxan in Autoimmune Disease
(MedPage Today) -- Repeated doses of rituximab in patients with vasculitis or lupus had no association with increased rates of low immunoglobulin (Ig)G, an important infection-fighting component of the immune system, a retrospective study found. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - May 28, 2014 Category: Infectious Diseases Source Type: news

Lupus Therapies Continue to Evolve
May is National Lupus Awareness Month, a time to think about lupus and the challenges it presents to patients. Learn about this chronic, autoimmune disease and the promise of future therapies. (Source: FDA Consumer Updates)
Source: FDA Consumer Updates - May 27, 2014 Category: Consumer Health News Source Type: news

Vaccines and Biologics: Questions Remain
(MedPage Today) -- Vaccinations for patients with autoimmune diseases -- specifically patients being treated with biologics -- bring with them a variety of issues, including disease-specific, medication-related, and vaccine-associated factors, researchers suggested. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - May 24, 2014 Category: Infectious Diseases Source Type: news

Cells: RaDAR guides proteins into the nucleus
A novel pathway by which proteins are actively and specifically shuttled into the nucleus of a cell has been discovered by scientists. The finding captures a precise molecular barcode that flags proteins for such import and describes the biochemical interaction that drives this critically important process. The discovery could help illuminate the molecular dysfunction that underpins a broad array of ailments, ranging from autoimmune diseases to cancers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 22, 2014 Category: Science Source Type: news

RaDAR guides proteins into the nucleus
(Ludwig Institute for Cancer Research) A Ludwig Cancer Research study has identified a novel pathway by which proteins are actively and specifically shuttled into the nucleus of a cell. Published online today in Cell, the finding captures a precise molecular barcode that flags proteins for such import and describes the biochemical interaction that drives this critically important process. The discovery could help illuminate the molecular dysfunction that underpins a broad array of ailments, ranging from autoimmune diseases to cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 22, 2014 Category: Cancer & Oncology Source Type: news

AR CAG repeat and autoimmunity in lupus
Clinical and experimental evidence support a role for gonadal steroids in modulating the expression and course of autoimmune diseases such as lupus. It is not known if inherited variation in sensitivity to circulating androgenic hormones could influence the manifestations of such a disease. Olsen and colleagues found that shorter AR CAG repeat lengths in lupus subjects correlated with a higher Systemic Lupus Erythematosus Disease Activity Index score, higher ANA levels, expression of a broader array of IgG autoantibodies, more severe clinical manifestations, and more exuberant humoral autoimmunity. These findings suggest a...
Source: Society for Endocrinology - May 21, 2014 Category: Endocrinology Source Type: news

Patient Led Research Paving the Way For Early Diagnosis of Autoimmune...
A new patient-centered research study led by the International Foundation for Autoimmune Arthritis aims to develop a new standard in early detection and diagnosis of Autoimmune Arthritis diseases. As...(PRWeb May 19, 2014)Read the full story at http://www.prweb.com/releases/2014/05/prweb11863493.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - May 19, 2014 Category: Pharmaceuticals Source Type: news

Molecules involved in rheumatoid arthritis angiogenesis identified
Two protein molecules that fit together as lock and key seem to promote the abnormal formation of blood vessels in joints affected by rheumatoid arthritis, according to researchers who found that the substances are present at higher levels in the joints of patients affected by the disease. Rheumatoid arthritis is a chronic autoimmune inflammatory disease in which the body's own defenses attack the tissues lining the joints, causing painful swelling and bone erosion that can ultimately lead to joint deformities. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 16, 2014 Category: Science Source Type: news

B cells produce antibodies 'when danger calls, but not when it whispers,' scientists report
The immune system’s B cells protect us from disease by producing antibodies, or "smart bullets," that specifically target invaders such as pathogens and viruses while leaving harmless molecules alone. But how do B cells determine whether a threat is real and whether to start producing these weapons? An international team of life scientists shows in the May 16 issue of the journal Science how and why these cells respond only to true threats. "It is critical for B cells to respond either fully or not at all. Anything in between causes disease," said the study’s senior author, Alexander Hoffma...
Source: UCLA Newsroom: Health Sciences - May 15, 2014 Category: Universities & Medical Training Source Type: news

Shingle Risk High in Lupus, RA, COPD
(MedPage Today) -- Patients with autoimmune diseases and certain other chronic conditions are at increased risk for herpes zoster, a U.K. case-control study found. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - May 14, 2014 Category: Geriatrics Source Type: news

Neil Riordan, PhD Presents at American Academy of Anti-Aging...
Neil Riordan, PhD will Present “Umbilical Cord Mesenchymal Stem Cells in the Treatment of Autoimmune Diseases” at the 22nd Annual World Congress on Anti-Aging, Regenerative and Aesthetic Medicine at...(PRWeb May 13, 2014)Read the full story at http://www.prweb.com/releases/2014/05/prweb11847056.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - May 13, 2014 Category: Pharmaceuticals Source Type: news

How immune cells use steroids
Some immune cells turn themselves off by producing a steroid, researchers have found. The findings have implications for the study of cancers, autoimmune diseases and parasitic infections. "We were really surprised to see that these immune cells are producing a steroid. In cell culture, we see that the steroids play a part in regulating T cell proliferation," says the study's designer. "We had already seen that T-helper cells were producing steroids, but initially we were blind -- what was going on?" (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 8, 2014 Category: Science Source Type: news

How immune cells use steroids
(European Molecular Biology Laboratory) Researchers at the European Bioinformatics Institute and the Wellcome Trust Sanger Institute have discovered that some immune cells turn themselves off by producing a steroid. The findings, published in Cell Reports, have implications for the study of cancers, autoimmune diseases and parasitic infections. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 8, 2014 Category: Biology Source Type: news

Outwitting immunity to treat disease: Start-up raises 37 millions dollars
(Ecole Polytechnique Fédérale de Lausanne) What do multiple sclerosis, type I diabetes and food allergies have in common? All these conditions are caused by an abnormal immune response. Anokion is developing an extremely promising technology to treat autoimmune conditions and other maladies. This method was able tp completely prevent disease in mice that were developing type I diabetes. The first clinical trials on humans are planned for 2017. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 5, 2014 Category: Cancer & Oncology Source Type: news

What is in the Differential Diagnosis of Purpura?
Discussion Children presenting with rashes are common but certain characteristics may be concerning such as descriptions of petechiae or purpura. Purpura are characterized by non-blanching skin lesions between 3-10 mm in size that are caused by bleeding into the skin. Usually they are reddish-purplish hence the name purpura coming from the Latin word. Non-blanching lesions that are 10 mm are ecchymosis. Henoch-Schönlein purpura (HSP) is a generalized vasculitis that commonly involves the gastrointestinal tract, kidneys, skin and joints, and is especially seen in children 2-11 years old. Classically HSP presents with p...
Source: PediatricEducation.org - May 5, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Autoimmune diseases may succumb to new drug strategy
New pharmaceuticals to fight autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis and psoriasis, may be identified more effectively by adding genome analysis to standard drug screening, according to a new study. The three potential drug candidates chosen for this study, selected from a large library of screened chemicals, each knocked down the response of Th17 cells, a type of immune cell that drives many autoimmune diseases by attacking normal cells in the body. More specifically, the drugs homed in on an essential molecule within the Th17 cells. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 2, 2014 Category: Science Source Type: news

May eFactor
Birnbaum featured at EPA Earth Day event Board of Scientific Counselors advises NTP on draft concepts and more NIEHS and the Energy Future Coalition hold workshop on ultrafine particles from vehicle emissions Presentations and virtual forum mark Autism Awareness Month at NIEHS Centers focus on emerging environmental health science and collaboration Tsunami exercise helps prepare research community for disaster response The GuLF STUDY four years after the Deepwater Horizon oil spill NIEHS grantee honored for autism research at White House ceremony SOT honors NTP and NIEHS researchers NIEHS postdocs awarded NIH K99 ...
Source: Environmental Factor - NIEHS Newsletter - May 1, 2014 Category: Environmental Health Source Type: news