A specialist ’ s journey in health care advocacy
As an allergy, immunology, and autoimmune disease specialist, I frequently see patients whose stories are a harsh indictment of our medical system. They’ve been dismissed, misdiagnosed, and forced to navigate a maze designed for quick fixes, not the complexities they endure. These unseen patients fight multi-system illnesses that defy textbooks. Their journeys highlight just how
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A specialist’s journey in health care advocacy originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 9, 2024 Category: General Medicine Authors: Kara Wada, MD Tags: Physician Allergies & Immunology Source Type: blogs
Dump Punts
Apparently realizing that they were caught on the horns, as it were, the dumpsters handlers wrote a statement for him in which he tried to split the baby by saying that abortion policy should be left entirely up to the states. Presumably he agreed to this although his dementia is too far advanced for him to have written the statement.The whole issue has never been anything but opportunism for him. He proclaimed himself to be a strong supporter of abortion rights until he decided to run for president as a Republican, and then he had a very difficult time articulating exactly what he thought about the entire question until t...
Source: Stayin' Alive - April 8, 2024 Category: American Health Source Type: blogs
An Urgent Call to Raise Awareness of Heart Disease in Women
By KELLY CARROLL
There is a dire need to raise awareness about heart disease in women. It is the number one killer of American women, and key data points reveal a lack of cognizance among doctors and women.
An assessment of primary care physicians published in 2019 revealed that only 22% felt extremely well prepared to evaluate cardiovascular disease risks in female patients. A 2019 survey of American women showed that just 44% recognized heart disease as the number one cause of death in women. Ten years earlier, in 2009, the same survey found that 65% of American women recognized heart disease as the leading cause o...
Source: The Health Care Blog - April 5, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice heart disease Kelly Carroll Life Essential 8 prevention Womens health Source Type: blogs
Autoimmune disease flares: stress, grief, and management tips
Autoimmune diseases occur when the immune system mistakenly attacks healthy cells and tissues in the body. More than 80 recognized autoimmune diseases exist, including alopecia areata, rheumatoid arthritis, psoriasis, lupus, multiple sclerosis, celiac disease, scleroderma, and Raynaud’s. These conditions can cause a wide range of symptoms, making management crucial for maintaining a good quality of
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Autoimmune disease flares: stress, grief, and management tips originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 4, 2024 Category: General Medicine Authors: Nancie Wiseman Attwater Tags: Conditions Rheumatology Source Type: blogs
Interview with Stefany Shaheen: Revolutionizing diabetes care through cell therapies
I had the extraordinary opportunity to chat with Stefany Shaheen, the Chief Strategy Officer of Advanced Regenerative Manufacturing Institute (ARMI) and BioFab USA, about the transformative potential of cell therapies for individuals living with diabetes. Stefany shared her remarkable journey, insights on cell therapies’ current status, approval challenges, and how the diabetes community can contribute to advancing research in this field.
A few months before this discussion with Stefany, I had the opportunity to hear Dean Kamen speak at the recent ...
Source: Scott's Diabetes Blog - April 1, 2024 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs
Fight Aging! Newsletter, April 1st 2024
This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression can promote increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes.
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A Skeptical View of the Role of Nuclear DNA Damage in Aging
https://www.fightaging.org/archives/2024/03/a-skeptical-view-of-the-role-of-nuclear-dna-damage-in-aging/
It is evident and settled that stochastic nuclear DNA damag...
Source: Fight Aging! - March 31, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Predicting the Order of Arrival of the First Rejuvenation Therapies
It has been going on eight years since I last speculated on the order of arrival of the first rejuvenation therapies. Tempus fugit, and time for an updated version! Eight years is a long enough span of time for the first of those rejuvenation therapies to now exist, albeit in a prototypical form, arguably proven in principle but not concretely. The world progresses but my biases remain much the same: the first rejuvenation therapies to work well enough to merit the name will be based on the SENS vision, that aging is at root caused by a few classes of accumulated cell and tissue damage, and biotechnologies that either repa...
Source: Fight Aging! - March 25, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, March 25th 2024
This study also reports the expansion of satellite cells in human muscle with CR. This finding is critical to suggest translational relevance to the rodent data observed for more than a decade. Moreover, the increased expression of the plasminogen receptor Plg-RKT observed on human satellite cells during CR provided additional support for the theory that our rodent model is relevant to human biology.
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Interesting Insight into the Relationship Between TP53, Telomerase, and Telomere Length
https://www.fightaging.org/archives/2024/03/interesting-insight-into-the-relationship-between-t...
Source: Fight Aging! - March 24, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Puzzling Lack of Autoimmunity in Centenarians
Today's open access paper presents an interesting discussion of the apparent lack of age-related autoimmunity in centenarians. The immune system becomes ever more dysfunctional with age, and some of that dysfunction can take the form of maladaptive changes that either (a) allow the immune system to direct attack tissues or (b) disrupt important relationships between immune cells and the rest of a tissue. Far from all of these issues are well understood or even well identified as discrete problems distinct from the rest of degenerative aging. A potential type 4 diabetes was only comparatively recently discovered, for exampl...
Source: Fight Aging! - March 20, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, March 4th 2024
In conclusion, HSV (but not CMV) infection may be indicative of doubled dementia risk.
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Increased Dietary Leucine Activates mTOR Signaling in Macrophages, Accelerating Atherosclerosis
https://www.fightaging.org/archives/2024/02/increased-dietary-leucine-activates-mtor-signaling-in-macrophages-accelerating-atherosclerosis/
Leucine is an essential amino acid, only obtained from the diet rather than synthesized by our cells. Leucine supplementation has been proposed as a way to slow the loss of muscle mass with age, as leucine processing becomes dysregulated with aging in a way...
Source: Fight Aging! - March 3, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Repeated Cycles of a Fasting-Mimicking Diet Reduce Measures of Biological Age
We report on the secondary outcome measures of the FMD-trial (NCT02158897) which are biomarkers associated with aging or age-related diseases, and metabolic syndrome, including visceral and hepatic fat, lymphoid/myeloid ratios, and blood markers, which were not investigated in the original report.
We show that 3 FMD cycles in adult study participants are associated with reduced insulin resistance and other pre-diabetes markers, lower hepatic fat (as determined by magnetic resonance imaging), and increased lymphoid to myeloid ratio, an indicator of immune system age. Based on the Klemera-Doubal measure of biological a...
Source: Fight Aging! - February 27, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
What Does an Immunologist Do?
This post is part of a miniseries on the immune system. Be sure to check out the other posts in this series that you may have missed.
Immunology is the study of the immune system, including all the cells, tissues, and organs that work together to protect you from germs. A person who studies immunology is called an immunologist, and there are three types:
Researchers, who study the immune system in the laboratory to understand how it works or how it can go awry and find new treatments for immune system-related diseases
Doctors, who diagnose and care for patients with diseases related to the immune system, such as ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - February 12, 2024 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Injury and Illness Immunology Miniseries Infectious Diseases Medicines Microbes Research Roundup Source Type: blogs
Fight Aging! Newsletter, February 5th 2024
In conclusion, the Immunity and Redox Clocks allow BA quantification in mice and both the ImmunolAge and RedoxAge in mice relate to lifespan.
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Senolytic CAR T Cell Therapy Improves Health in Aged Mice
https://www.fightaging.org/archives/2024/01/senolytic-car-t-cell-therapy-improves-health-in-aged-mice/
To the degree that senescent cells in a tissue exhibit distinctive surface features, one can deploy technologies such as chimeric antigen receptor T cells to selectively destroy them. T cells will destroy whatever cell binds to the chimeric antigen receptor they are equipped w...
Source: Fight Aging! - February 4, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Biomarkers for Immunosenescence
The aging immune system exhibits a declining ability to destroy pathogens and dysfunctional, harmful cells. This is known as immunosenescence. There are ways to assess immune cell populations and their characteristics to measure the degree of immunosenescence, but this is comparatively costly and cannot be used on banked samples. Researchers here ask whether combinations of circulating proteins can instead be used to assess the degree of immunosenescence from a blood sample, and propose a few such biomarkers based on their analysis.
Inflammaging, the characteristics of immunosenescence, is characterized by continu...
Source: Fight Aging! - February 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Bonus Features – January 28, 2024 – 49% of orgs likely to invest in RCM tech in the next 18 months, v2 drafts of TEFCA Common Agreement and QHIN Technical Framework out, plus 27 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News and Studies
The Sequoia Project released a bundle of TEFCA draft documents, including v2 drafts of the Common Agreement and QHIN Technical Framework. Interested stakeholders have until February 5 to provide feedback.
About...
Source: EMR and HIPAA - January 28, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Interoperability Revenue Cycle Management 1upHealth AdhereHealth Aidéo Technologies Anatomy IT Andrea Kowalski Authenticx Clearsense Don Brown eClinicalWorks Emory Healthcare Epic Research Fathom First Health A Source Type: blogs
