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Histiocytosis: Symptoms and Treatment Information
Histiocytosis is also referred to as, "Langerhans Cell Histiocytosis (LCH)," or more formally as, "Histiocytosis X," and represents a group of rare disorders involving specific cells that usually have important roles as part of a person's immune system. (Source: Disabled World)
Source: Disabled World - October 7, 2014 Category: Disability Tags: Autoimmune Diseases Source Type: news

Efficacy of potential therapy for autoimmune disorder of muscle weakness
(University of Pennsylvania School of Medicine) Researchers have made a fast-acting 'vaccine' that can reverse the course of myasthenia gravis, a non-inherited autoimmune form of muscle weakness, in an animal model of the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 7, 2014 Category: Global & Universal Source Type: news

Pain receptor on T-cells discovered
T-cells -- a type of white blood cell that learns to recognize and attack microbial pathogens -- are activated by a pain receptor, scientists have discovered. The study shows that the receptor helps regulate intestinal inflammation in mice and that its activity can be manipulated, offering a potential new target for treating certain autoimmune disorders, such as Crohn's disease and possibly multiple sclerosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 5, 2014 Category: Science Source Type: news

Viral infection may trigger childhood diabetes in utero
A likely trigger for juvenile diabetes before birth has been identified by researchers who have put forth evidence that the autoimmune disease is initiated in utero. Women who contract a viral infection during pregnancy transmit viruses to their genetically susceptible fetuses, sparking the development of type 1 diabetes, they propose. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 3, 2014 Category: Science Source Type: news

Viral infection may trigger childhood diabetes in utero
(American Friends of Tel Aviv University) A new study from Tel Aviv University suggests a likely trigger for juvenile diabetes before birth. World-renowned TAU researcher professor Zvi Laron has put forth evidence that the autoimmune disease is initiated in utero. Women who contract a viral infection during pregnancy transmit viruses to their genetically susceptible fetuses, sparking the development of type 1 diabetes, he says. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 3, 2014 Category: Global & Universal Source Type: news

Infant's Early Diet Doesn't Change Celiac Disease Risk, Study Finds
Breast-feeding, waiting to introduce foods with gluten didn't prevent autoimmune disorder (Source: WebMD Health)
Source: WebMD Health - October 1, 2014 Category: Consumer Health News Source Type: news

Infant's Early Diet Doesn't Change Celiac Disease Risk, Study Finds
Breast-feeding, waiting to introduce foods with gluten didn't prevent autoimmune disorder Source: HealthDay Related MedlinePlus Pages: Breastfeeding, Celiac Disease, Infant and Newborn Nutrition (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 1, 2014 Category: Consumer Health News Source Type: news

The Dance Between The Immune System and Stem Cells
We named it the  immunoLinkTM We have been testing a growing number of Clients with our Quantibody Arrays. Many of of these clients have Autoimmune Disorder Diseases. These range from Rheumatoid Arthritis to Multiple Sclerosis.These arrays are designed to precisely measure factors or markers (proteins) that are dysregulated by these diseases. We measure the levels of these biomarkers in our Clients' Blood serum. The arrays have also been used to measure the levels of markers in plasma and cell culture supernatants.Based on results, we are finding links between immune system and stem cell health. We call this the ...
Source: Neuromics - September 30, 2014 Category: Neuroscience Tags: autoimmune disease G-CSF GM-CSF Human Mesenchymal Stem Cells immune response immunoLink Neural Progenitor Cells Neural Stem Cell Markers Source Type: news

Protecting the body from itself: How defense cells fight disease, but not themselves
A clearer relationship between two cells that serve our body's natural defense mechanisms against diseases and infections has now been gained through new research. The findings will help the medical community better understand autoimmunity and could pave the way for treatment of autoimmune diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 26, 2014 Category: Science Source Type: news

Discovery may lead to better treatments for autoimmune diseases, bone loss
Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 25, 2014 Category: Science Source Type: news

Autoimmune diseases, chronic inflammations: Advancing research
Multiple sclerosis, type 1 diabetes and lupus are autoimmune diseases in which the immune cells can no longer differentiate between friend and foe and thus attack the body's own tissue. Here, the immunoproteasome, which supplies the immune system with information on processes within the cell, plays a central role. Chemists have now discovered a way to inhibit its functionality, thereby laying the foundation for possible optimizations of existing medications. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 25, 2014 Category: Science Source Type: news

Spot on against autoimmune diseases and chronic inflammations
(Technische Universitaet Muenchen) Multiple sclerosis, type 1 diabetes and lupus are autoimmune diseases in which the immune cells can no longer differentiate between friend and foe and thus attack the body's own tissue. Here, the immunoproteasome, which supplies the immune system with information on processes within the cell, plays a central role. Chemists at Technische Universität München have now discovered a way to inhibit its functionality, thereby laying the foundation for possible optimizations of existing medications. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 25, 2014 Category: Biology Source Type: news

Protecting the body from itself
(Biomedical Sciences Institutes (BMSI)) Scientists from A*STAR's Bioprocessing Technology Institute have established a clearer relationship between two cells which serve our body's natural defense mechanisms against diseases and infections. Their findings, published in the prestigious journal Cell Reports, will help the medical community better understand autoimmunity and could pave the way for treatment of autoimmune diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 25, 2014 Category: Global & Universal Source Type: news

Findings give hope to plant extract as possible lupus treatment
(University of Houston) Lupus is a chronic autoimmune disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. New findings by a biomedical engineer and his team at the University of Houston raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks and side effects often associated with current treatments for this disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 24, 2014 Category: Global & Universal Source Type: news

Math model designed to replace invasive kidney biopsy for lupus patients
Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus. The model could also be used to monitor the effectiveness of experimental treatments for inflammation and fibrosis, researchers say. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 17, 2014 Category: Science Source Type: news

Math model designed to replace invasive kidney biopsy for lupus patients
(Ohio State University) Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 17, 2014 Category: Global & Universal Source Type: news

Autoimmune Diseases Tied to Eating Disorders
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 16, 2014 Category: Journals (General) Source Type: news

Autoimmune Diseases Tied to Eating Disorders
Several autoimmune diseases have been linked to, and may even play a role in the development of, eating disorders, new research suggests. (Source: WebMD Health)
Source: WebMD Health - September 12, 2014 Category: Consumer Health News Source Type: news

Brain inflammation dramatically disrupts memory retrieval networks, study finds
Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to scientists. The study specifically identifies how immune system signaling molecules, called cytokines, impair communication among neurons in the hippocampus, an area of the brain critical for discrimination memory. The findings offer insight into why cognitive deficits occurs in people undergoing chemotherapy and those with autoimmune or neurodegenerative diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 12, 2014 Category: Science Source Type: news

Cytokines and Neuropathic Pain
I have been frequently posting results of testing blood serum of our clients suffering from Autoimmune (including Neuroimmuno) Diseases and Autistic Children. Our testing includes both standard medical testing (serum levels of toxins, metals, pathogen loads and markers like Cortisol, CRP, CDs, ALPS, NSE, S100b). In addition, we also doing testing using our Quantibody® Antibody.Many of the clients report chronic mild to severe neuropathic pain.By definition, this pain encompasses a series of heterogeneous conditions with some similar clinical manifestations. Peripheral examples include traumatic nerve injury, diabetic p...
Source: Neuromics - September 10, 2014 Category: Neuroscience Tags: chronic pain Cytokine Antibody Arrays Diabetic Neuropathy Inflammatory pain inflammatory response Interleukins neuroinflammatory cytokines Neuropathic Pain Source Type: news

How skin falls apart: Pathology of autoimmune skin disease revealed at the nanoscale
Researchers studying a rare, blistering disease have discovered new details of how autoantibodies destroy healthy cells in skin. The research has the potential to help clinicians identify who may be at risk for developing Pemphigus vulgaris (PV), an autoimmune skin disorder, by distinguishing pathogenic (disease-causing) autoimmune antibodies from other nonpathogenic autoimmune antibodies. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 10, 2014 Category: Science Source Type: news

Jim Sullivan on Improving the Lives of Patients
At AbbVie, research and innovation are the cornerstones of our business as a global biopharmaceutical company. We focus on developing medicines that deliver strong clinical performance, provide more patient benefit and deliver economic value, particularly where there is significant need around the world in certain disease areas.  Arthritis is an example of a disease where we have the opportunity to continue to make headway to improve the lives of patients. According to the U.S. Centers for Disease Control and Prevention (CDC) prevalence of musculoskeletal diseases could increase from 52 million people in the U.S. to 6...
Source: PHRMA - September 9, 2014 Category: Pharmaceuticals Authors: Emily Source Type: news

VTE Risk High in Autoimmune Muscle Disease
(MedPage Today) -- Patients with the inflammatory myopathies polymyositis and dermatomyositis had markedly elevated risks for venous thromboembolic events, a population-based study in Canada found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 9, 2014 Category: Cardiology Source Type: news

Autoimmune Diseases Implicated in Eating DisordersAutoimmune Diseases Implicated in Eating Disorders
Autoimmune diseases are associated with, and may even play a role in the development of, eating disorders. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - September 8, 2014 Category: Psychiatry Tags: Dermatology News Source Type: news

How immunotherapy may treat multiple sclerosis
Conclusion This mouse study using a mouse model of MS has found that the dose-escalation protocol is extremely important for inducing tolerance, in this case a small fragment of myelin basic protein. Escalation dose immunotherapy minimised immune system activation and proliferation during the early stages, and caused changes in gene expression that caused the attacking immune cells to express regulatory genes and to become suppressive. The researchers hope that some of the changes in immune cells and in gene expression that they have identified can be used in clinical studies of tolerance-inducing treatments for autoimmun...
Source: NHS News Feed - September 4, 2014 Category: Consumer Health News Tags: Genetics/stem cells Medical practice Source Type: news

Breakthrough hope for MS treatment
Scientists say they have discovered how to “switch off” autoimmune diseases such as multiple sclerosis. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - September 4, 2014 Category: Nursing Source Type: news

Multiple sclerosis could be 'switched off' by retraining immune system
Scientists believe they are close to developing a drug which could 'switch off' autoimmune diseases like Multiple sclerosis by training the body to stop attacking itself (Source: Telegraph Health)
Source: Telegraph Health - September 3, 2014 Category: Consumer Health News Source Type: news

Multiple Sclerosis could be 'switched off' by retraining immune system
Scientists believe they are close to developing a drug which could 'switch off' autoimmune diseases like Multiple Sclerosis by training the body to stop attacking itself (Source: Telegraph Health)
Source: Telegraph Health - September 3, 2014 Category: Consumer Health News Source Type: news

Breakthrough hope for MS treatment as scientists discover how to 'switch off' autoimmune diseases 
Researchers at the University of Bristol have found a way of stopping cells from attacking healthy body tissue, and it is hoped the insight will pave the way for new treatments. (Source: the Mail online | Health)
Source: the Mail online | Health - September 3, 2014 Category: Consumer Health News Source Type: news

Scientists discover how to 'switch off' autoimmune diseases
Scientists have made an important breakthrough in the fight against debilitating autoimmune diseases such as multiple sclerosis by revealing how to stop cells attacking healthy body tissue. Rather than the body's immune system destroying its own tissue by mistake, researchers have discovered how cells convert from being aggressive to actually protecting against disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 3, 2014 Category: Science Source Type: news

Scientists discover how to ‘switch off’ autoimmune diseases
Scientists have made an important breakthrough in the fight against debilitating autoimmune diseases such as multiple sclerosis by revealing how to stop cells attacking healthy body tissue. (Source: University of Bristol news)
Source: University of Bristol news - September 3, 2014 Category: Universities & Medical Training Tags: Research; Faculty of Medical and Veterinary Sciences, Faculty of Medical and Veterinary Sciences, School of Cellular and Molecular Medicine, Faculty of Engineering, Faculty of Engineering, Merchant Venturers' School of Engineering, Computer Science, Facul Source Type: news

Systemic effects of intratympanic steroids
Intratympanic glucocorticoids are effective in the treatment of sudden sensorineural hearing loss, the stabilization of Ménière's disease, and in autoimmune ear disorders. Intratympanic administration should minimise systemic side effects. Novoa and colleagues carried out a prospective cohort study, finding that intratympanic dexamethason did not interfere with endogenous cortisol secretion or bone metabolism. Read the full article at Novoa et al. (2014) Endocrine Connections 3 127–131; DOI:10.1530/EC-14-0076 (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 29, 2014 Category: Endocrinology Source Type: news

Hyperthyroidism, Hypothyroidism, and Screening in PregnancyHyperthyroidism, Hypothyroidism, and Screening in Pregnancy
Should pregnant women with autoimmune thyroid disease receive levothyroxoine? What are the risks and benefits? Endocrine Practice (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 29, 2014 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news

CU scientists' discovery could lead to new cancer treatment
(The Bawmann Group) A team of scientists from the University of Colorado School of Medicine has reported the breakthrough discovery of a process to expand production of stem cells used to treat cancer patients. These findings could have implications that extend beyond cancer, including treatments for inborn immunodeficiency and metabolic conditions and autoimmune diseases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 29, 2014 Category: Cancer & Oncology Source Type: news

Video Game Can Help MS Patients Reduce Falls
Falls are a serious concern for patients with multiple sclerosis (MS), an autoimmune disease of the central nervous system, in which the body's immune system attacks the protective covering or sheath surrounding nerve fibers.  The risk for serious head and extremity injuries can increase with the duration of the disease. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 26, 2014 Category: Pharmaceuticals Authors: Robert Glatter, MD Source Type: news

Patients with eating disorders have an increased risk of autoimmune diseases
(University of Helsinki) Finnish researchers have observed an association between eating disorders and several autoimmune diseases with different genetic backgrounds. Their findings support the link between immune-mediated mechanisms and development of eating disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 26, 2014 Category: Global & Universal Source Type: news

Drug Restores Hair in Alopecia Patients: FAQ
A drug used to treat a rare bone marrow cancer caused hair to grow back in some people with alopecia areata, an autoimmune disease that attacks the hair follicles, scientists have found. (Source: WebMD Health)
Source: WebMD Health - August 19, 2014 Category: Consumer Health News Source Type: news

Stem-Kine and Stem Cell Activation
For Health and FitnessI have referenced our studies of commercially available Stem Cell Activators or Boosters. Many commercially available supplements make claims of boosting the body's ability increase the production of stem cells.The catalyst for our researching the active ingredients in these boosters was the desire to find a cost effective way to treat clients with certain autoimmune diseases versus the expensive stem cell transplant options.  We also believed that these supplements could also improve athletic performance.We have an active internal program to test these in culture using our human stem cell based ...
Source: Neuromics - August 18, 2014 Category: Neuroscience Tags: stem cell activation stem cell boosters stem cell boosting stem-kine StemKine Source Type: news

FDA-approved drug restores hair in patients with alopecia areata
Researchers have identified the immune cells responsible for destroying hair follicles in people with alopecia areata, a common autoimmune disease that causes hair loss, and have tested an FDA-approved drug that eliminated these immune cells and restored hair growth in a small number of patients. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 18, 2014 Category: Science Source Type: news

Bone marrow drug could treat alopecia
Conclusion This is valuable laboratory research that identifies the specific type of immune cell (CD8+NKG2D+ T cells) that is involved in the disease process of alopecia. It further identifies several signalling molecules that are drivers of this T cell activity. The researchers then demonstrate that giving two molecular treatments to block the signalling molecules – ruxolitinib (currently licensed in the UK to treat certain bone marrow disorders) and tofacitinib (not currently licensed for any condition in the UK) – were effective in preventing and reversing the disease process in mice with alopecia. These fi...
Source: NHS News Feed - August 18, 2014 Category: Consumer Health News Tags: Medication Source Type: news

New Drug Helps Some Bald Patients Regrow Hair
The drug, which suppresses immune system activity, showed significant results for several sufferers of the autoimmune disease alopecia areata. (Source: NYT Health)
Source: NYT Health - August 17, 2014 Category: Consumer Health News Authors: By PAM BELLUCK Tags: Hair Arthritis Research Nature Medicine (Journal) Columbia University Medical Center Raphael Clynes Bristol Myers Squibb Company BMY NYSE Alopecia Areata Christiano, Angela Immune System Source Type: news

FDA-approved drug restores hair in patients with Alopecia Areata
(Columbia University Medical Center) Researchers at Columbia University Medical Center have identified the immune cells responsible for destroying hair follicles in people with alopecia areata, a common autoimmune disease that causes hair loss, and have tested an FDA-approved drug that eliminated these immune cells and restored hair growth in a small number of patients.The results appear in today's online issue of Nature Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2014 Category: Global & Universal Source Type: news

Genetic signal prevents immune cells from turning against the body
(Salk Institute) Salk scientists find a control signal for the immune system that could help treat autoimmune diseases and cancer. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 14, 2014 Category: Biology Source Type: news

National Psoriasis Foundation on Improving the Lives of Patients
Millions of Americans with psoriatic arthritis—a serious disease that causes pain, swelling and stiffness of the joints and tendons, and can result in joint damage if left untreated—struggle to get the health care and treatments they need to manage their condition. National Psoriasis Foundation plans to change with the largest realignment and expansion of its psoriatic arthritis program. For nearly two decades, the Psoriasis Foundation has provided disease-management services and information to people with psoriatic arthritis (PsA), which affects as many as one in three people with psoriasis, the most common au...
Source: PHRMA - August 13, 2014 Category: Pharmaceuticals Authors: Emily Source Type: news

Npf
PartnerThe National Psoriasis Foundation (NPF) is a non-profit, voluntary health agency dedicated to finding a cure for psoriasis and psoriatic arthritis and eliminating their devastating effects through research, advocacy and education.  Founded in 1968, the Psoriasis Foundation has evolved to become the leading patient advocacy group for the 7.5 million Americans living with psoriasis and psoriatic arthritis.  As emerging research continues to demonstrate the serious, systemic effects of these chronic autoimmune diseases, our highest priority is to find a cure. NPFNational.Psoriasis.FoundationCompany: Arth...
Source: PHRMA - August 13, 2014 Category: Pharmaceuticals Authors: Emily Source Type: news

Gene that controls nerve conduction velocity linked to multiple sclerosis
A novel gene that controls nerve conduction velocity has been identified in a new study. Investigators report that even minor reductions in conduction velocity may aggravate disease in multiple sclerosis (MS) patients and in mice bred for the MS-like condition experimental autoimmune encephalomyelitis (EAE). (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 13, 2014 Category: Science Source Type: news

Gene that controls nerve conduction velocity linked to multiple sclerosis
(Elsevier Health Sciences) A new study published in The American Journal of Pathology identifies a novel gene that controls nerve conduction velocity. Investigators report that even minor reductions in conduction velocity may aggravate disease in multiple sclerosis patients and in mice bred for the multiple sclerosis-like condition experimental autoimmune encephalomyelitis. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 13, 2014 Category: Biology Source Type: news

'Worm pill' could ease autoimmune disease symptoms
Experts believe a molecule in parasitic worms could help explain why worm infections can effectively treat a range of autoimmune diseases, including multiple sclerosis, psoriasis, rheumatoid arthritis and lupus. The study successfully identified peptides from parasitic worms that suppress the body's immune response. Researchers believe this could pave the way for a new drug containing the peptide to provide relief from the symptoms of autoimmune diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 11, 2014 Category: Science Source Type: news

Is the gut microbiome a potential cause and therapeutic target for autoimmune diseases like multiple sclerosis?
(Mary Ann Liebert, Inc./Genetic Engineering News) Numerous risk factors are believed to contribute to the development of autoimmune disorders such as multiple sclerosis, and new research is focusing on the role that bacteria in the gastrointestinal tract as well as other cell stress-related chemical signals could have in stimulating inflammation in the central nervous system and activating immunostimulatory cytokines. Two comprehensive Review articles are part of a focus on 'Cytokines in Neuroinflammation and Immunity' in a special issue of Journal of Interferon & Cytokine Research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 7, 2014 Category: Global & Universal Source Type: news

Gabriela Lavezzari on Improving the Lives of Patients with Arthritis
Many people are unaware of the impact of arthritis and related musculoskeletal diseases in the United States. They affect approximately 52.5 million Americans of all ages, races and genders. The biopharmaceutical industry is making great strides towards new treatments with 92 medicines in the pipeline which have the potential to help patients live more active and productive lives. Work on these treatments is more imperative than ever as 67 million people could be diagnosed with some form of musculoskeletal disease by 2030, according to the U.S. Centers for Disease Control and Prevention. Earlier this year, PhRMA joined 10...
Source: PHRMA - August 4, 2014 Category: Pharmaceuticals Authors: Emily Source Type: news